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Drug Evaluations

Brodalumab-an IL-17RA monoclonal antibody for psoriasis and psoriatic arthritis

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Michael Roman & Melvin W Chiu. (2017) Spotlight on brodalumab in the treatment of moderate-to-severe plaque psoriasis: design, development, and potential place in therapy. Drug Design, Development and Therapy 11, pages 2065-2075.
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Anna Balato, Emanuele Scala, Nicola Balato, Giuseppina Caiazzo, Roberta Di Caprio, Giuseppe Monfrecola, Annunziata Raimondo, Serena Lembo & Fabio Ayala. (2017) Biologics that inhibit the Th17 pathway and related cytokines to treat inflammatory disorders. Expert Opinion on Biological Therapy 17:11, pages 1363-1374.
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Andrea Chiricozzi, Rosita Saraceno, Lucia Novelli, Monika Fida, Francesco Caso, Raffaele Scarpa, Luisa Costa, Roberto Perricone, Marco Romanelli, Sergio Chimenti & Maria Sole Chimenti. (2016) Small molecules and antibodies for the treatment of psoriasis: a patent review (2010–2015). Expert Opinion on Therapeutic Patents 26:7, pages 757-766.
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Daniel Wendling. (2016) An overview of investigational new drugs for treating ankylosing spondylitis. Expert Opinion on Investigational Drugs 25:1, pages 95-104.
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Menglin Zhu, Qian Ding, Zhongxiao Lin, Rong Fu, Fuyuan Zhang, Zhaoyi Li, Mei Zhang & Yizhun Zhu. (2023) New Targets and Strategies for Rheumatoid Arthritis: From Signal Transduction to Epigenetic Aspect. Biomolecules 13:5, pages 766.
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Yang Yu, Robert M. Weiss & Shun-Guang Wei. (2022) Brain Interleukin-17A contributes to neuroinflammation and cardiac dysfunction in rats with myocardial infarction. Frontiers in Neuroscience 16.
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Wei-Yu Chen, Shao-Chuan Chen, Shou-Yi Hsu, Yu-An Lin, Chun-Ming Shih, Chun-Yao Huang, Kuo-Hsien Wang & Ai-Wei Lee. (2022) Annoying Psoriasis and Atopic Dermatitis: A Narrative Review. International Journal of Molecular Sciences 23:9, pages 4898.
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Siti Farah Rahmawati, Maurice te Velde, Huib A. M. Kerstjens, Alexander S. S. Dömling, Matthew Robert Groves & Reinoud Gosens. (2021) Pharmacological Rationale for Targeting IL-17 in Asthma. Frontiers in Allergy 2.
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Arsen Arakelyan, Lilit Nersisyan, Maria Nikoghosyan, Siras Hakobyan, Arman Simonyan, Lydia Hopp, Henry Loeffler-Wirth & Hans Binder. (2019) Transcriptome-Guided Drug Repositioning. Pharmaceutics 11:12, pages 677.
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Navin Kumar Verma, Maurice Adrianus Monique van Steensel, Praseetha Prasannan, Zhi Sheng Poh, Alan D. Irvine & Hazel H. Oon. 2019. Imaging Technologies and Transdermal Delivery in Skin Disorders. Imaging Technologies and Transdermal Delivery in Skin Disorders 35 59 .
Farida Benhadou, Dillon Mintoff & Véronique del Marmol. (2019) Psoriasis: Keratinocytes or Immune Cells – Which Is the Trigger?. Dermatology 235:2, pages 91-100.
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Oana Joean, Anja Hueber, Felix Feller, Adan Chari Jirmo, Matthias Lochner, Anna-Maria Dittrich & Melanie Albrecht. (2017) Suppression of Th17-polarized airway inflammation by rapamycin. Scientific Reports 7:1.
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Mohn’d AbuHilal, Scott Walsh & Neil Shear. (2016) The Role of IL-17 in the Pathogenesis of Psoriasis and Update on IL-17 Inhibitors for the Treatment of Plaque Psoriasis. Journal of Cutaneous Medicine and Surgery 20:6, pages 509-516.
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Ibrahim Sulaiman, Jonathan Chee Woei Lim, Hon Liong Soo & Johnson Stanslas. (2016) Molecularly targeted therapies for asthma: Current development, challenges and potential clinical translation. Pulmonary Pharmacology & Therapeutics 40, pages 52-68.
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Luisa Senra, Romaine Stalder, David Alvarez Martinez, Carlo Chizzolini, Wolf-Henning Boehncke & Nicolò Costantino Brembilla. (2016) Keratinocyte-Derived IL-17E Contributes to Inflammation in Psoriasis. Journal of Investigative Dermatology 136:10, pages 1970-1980.
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Jeffrey T. Guptill, Madhu Soni & Matthew N. Meriggioli. (2015) Current Treatment, Emerging Translational Therapies, and New Therapeutic Targets for Autoimmune Myasthenia Gravis. Neurotherapeutics 13:1, pages 118-131.
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Daniel Wendling. (2015) Interleukin-17 targeted therapies in axial spondyloarthritis. Immunotherapy 7:11, pages 1125-1128.
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Beatrice Dyring-Andersen, Lone Skov & Claus Zachariae. (2015) Targeting IL-17 with ixekizumab in patients with psoriasis. Immunotherapy 7:9, pages 957-966.
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