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Editorial

MicroRNAs in cancer therapeutics: “from the bench to the bedside

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Keep up to date with the latest research on this topic with citation updates for this article.

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Charles Asakiya, Liye Zhu, Jieyu Yuhan, Longjiao Zhu, Kunlun Huang & Wentao Xu. (2022) Current progress of miRNA-derivative nucleotide drugs: modifications, delivery systems, applications. Expert Opinion on Drug Delivery 19:4, pages 435-450.
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Lihua Dong, Jingjing Huang, Peng Zu, Jing Liu, Xue Gao, Jianwei Du & Yufu Li. (2021) Transcription factor 3 (TCF3) combined with histone deacetylase 3 (HDAC3) down-regulates microRNA-101 to promote Burkitt lymphoma cell proliferation and inhibit apoptosis. Bioengineered 12:1, pages 7995-8005.
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Jing Xue, Jiali Yang, Meihui Luo, William C. Cho & Xiaoming Liu. (2017) MicroRNA-targeted therapeutics for lung cancer treatment. Expert Opinion on Drug Discovery 12:2, pages 141-157.
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Articles from other publishers (33)

Yongan Song, Leonardo Kelava & István Kiss. (2023) MiRNAs in Lung Adenocarcinoma: Role, Diagnosis, Prognosis, and Therapy. International Journal of Molecular Sciences 24:17, pages 13302.
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Alti Dayakar, Kumar D. Shanmukha & Suresh K. Kalangi. (2022) Spectrum of microRNAs and their target genes in cancer: intervention in diagnosis and therapy. Molecular Biology Reports 49:7, pages 6827-6846.
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Yunhua Guo, Jianpu Tang, Chi Yao & Dayong Yang. (2021) Multimodules integrated functional DNA nanomaterials for intelligent drug delivery . WIREs Nanomedicine and Nanobiotechnology 14:1.
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Shadab Md, Nabil A. Alhakamy, Shahid Karim, Gamal A Gabr, Mohammad Kashif Iqubal & Samar S. A. Murshid. (2021) Signaling Pathway Inhibitors, miRNA, and Nanocarrier-Based Pharmacotherapeutics for the Treatment of Lung Cancer: A Review. Pharmaceutics 13:12, pages 2120.
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Soha Reda El Sayed, Justine Cristante, Laurent Guyon, Josiane Denis, Olivier Chabre & Nadia Cherradi. (2021) MicroRNA Therapeutics in Cancer: Current Advances and Challenges. Cancers 13:11, pages 2680.
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Sachchida Nand Pandey. 2021. Skin Cancer: Pathogenesis and Diagnosis. Skin Cancer: Pathogenesis and Diagnosis 101 130 .
Nicholas J. Monteleone & Carol S. Lutz. (2020) miR-708-5p enhances erlotinib/paclitaxel efficacy and overcomes chemoresistance in lung cancer cells. Oncotarget 11:51, pages 4699-4721.
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Qiushuang Zhang, Fei Ding, Xinlong Liu, Jian Shen, Yue Su, Jiwen Qian, Xinyuan Zhu & Chuan Zhang. (2020) Nanobody-guided targeted delivery of microRNA via nucleic acid nanogel to inhibit the tumor growth. Journal of Controlled Release 328, pages 425-434.
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Margherita Ratti, Andrea Lampis, Michele Ghidini, Massimiliano Salati, Milko B. Mirchev, Nicola Valeri & Jens C. Hahne. (2020) MicroRNAs (miRNAs) and Long Non-Coding RNAs (lncRNAs) as New Tools for Cancer Therapy: First Steps from Bench to Bedside. Targeted Oncology 15:3, pages 261-278.
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Monica Neagu, Carolina Constantin, Sanda Maria Cretoiu & Sabina Zurac. (2020) miRNAs in the Diagnosis and Prognosis of Skin Cancer. Frontiers in Cell and Developmental Biology 8.
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Qing‐feng Ni, Yan Zhang, Jia‐wei Yu, Ru‐heng Hua, Qu‐hui Wang & Jian‐wei Zhu. (2019) miR‐92b promotes gastric cancer growth by activating the DAB2IP‐mediated PI3K/AKT signalling pathway. Cell Proliferation 53:1.
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Lin Fu, Jialei Qi, Xiang Gao, Ninghan Zhang, Huihui Zhang, Rong Wang, Linyan Xu, Yao Yao, Mingshan Niu & Kailin Xu. (2019) High expression of miR‐338 is associated with poor prognosis in acute myeloid leukemia undergoing chemotherapy. Journal of Cellular Physiology 234:11, pages 20704-20712.
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Maria Angelica Cortez, Simone Anfossi, Rishab Ramapriyan, Hari Menon, Semra Cemre Atalar, Maureen Aliru, James Welsh & George A. Calin. (2019) Role of miRNAs in immune responses and immunotherapy in cancer. Genes, Chromosomes and Cancer 58:4, pages 244-253.
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Lucy Wanjiku Macharia, Caroline Muriithi Wanjiru, Marianne Wanjiru Mureithi, Claudia Maria Pereira, Valéria Pereira Ferrer & Vivaldo Moura-Neto. (2019) MicroRNAs, Hypoxia and the Stem-Like State as Contributors to Cancer Aggressiveness. Frontiers in Genetics 10.
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Jing Yu, Yifan Lv, Fengliang Wang, Xiaocen Kong, Wenjuan Di, Juan Liu, Yunlu Sheng, Shan Lv & Guoxian Ding. (2019) MiR-27b-3p Inhibition Enhances Browning of Epididymal Fat in High-Fat Diet Induced Obese Mice. Frontiers in Endocrinology 10.
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Yu Hu, Hayley Dingerdissen, Samir Gupta, Robel Kahsay, Vijay Shanker, Quan Wan, Cheng Yan & Raja Mazumder. (2018) Identification of key differentially expressed MicroRNAs in cancer patients through pan-cancer analysis. Computers in Biology and Medicine 103, pages 183-197.
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Wei Wang, Peng Lin, Haiying Yao, Xi Jia, Jirui Sun & Lin Feng. (2018) MicroRNA-4728 serves as a suppressor and antagonist of oncogenic MAPK in Burkitt lymphoma. Saudi Journal of Biological Sciences 25:5, pages 982-985.
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Dipta Sengupta, Moonmoon Deb & Samir Kumar Patra. (2018) Antagonistic activities of miR-148a and DNMT1: Ectopic expression of miR-148a impairs DNMT1 mRNA and dwindle cell proliferation and survival. Gene 660, pages 68-79.
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Jie Li, Yuanhui Lai, Jieyi Ma, Yue Liu, Jiong Bi, Longjuan Zhang, Lianzhou Chen, Chen Yao, Weiming Lv, Guangqi Chang, Shenming Wang, Mao Ouyang & Wenjian Wang. (2017) miR-17-5p suppresses cell proliferation and invasion by targeting ETV1 in triple-negative breast cancer. BMC Cancer 17:1.
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Minghao Xie, Huabo Qin, Qianxin Luo, Qunsheng Huang, Xiaosheng He, Zihuan Yang, Ping Lan & Lei Lian. (2017) MicroRNA-30a regulates cell proliferation and tumor growth of colorectal cancer by targeting CD73. BMC Cancer 17:1.
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Nilesh Kalariya, Kelly Brassil & George Calin. (2017) MicroRNAs: Clinical Trials and Potential Applications
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Jisce R Puik, Laura L Meijer, Tessa YS Le Large, Mireia Mato Prado, Adam E Frampton, Geert Kazemier & Elisa Giovannetti. (2017) miRNA profiling for diagnosis, prognosis and stratification of cancer treatment in cholangiocarcinoma. Pharmacogenomics 18:14, pages 1343-1358.
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Lauren Anton, Ann DeVine, Luz-Jeannette Sierra, Amy G. Brown & Michal A. Elovitz. (2017) miR-143 and miR-145 disrupt the cervical epithelial barrier through dysregulation of cell adhesion, apoptosis and proliferation. Scientific Reports 7:1.
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Lobna Elkhadragy, Minyi Chen, Kennon Miller, Muh-Hwa Yang & Weiwen Long. (2017) A regulatory BMI1/let-7i/ERK3 pathway controls the motility of head and neck cancer cells. Molecular Oncology 11:2, pages 194-207.
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Andrew J. Stacy, Michael P. Craig, Suraj Sakaram & Madhavi Kadakia. (2016) ΔNp63α and microRNAs: leveraging the epithelial-mesenchymal transition. Oncotarget 8:2, pages 2114-2129.
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Lu-Jia Chen, Lian Yang, Xing Cheng, Yin-Kai Xue & Li-Bo Chen. (2017) Overexpression of miR-24 Is Involved in the Formation of Hypocoagulation State after Severe Trauma by Inhibiting the Synthesis of Coagulation Factor X. Disease Markers 2017, pages 1-7.
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Edoardo Missiaglia, Chris J. Shepherd, Ewa Aladowicz, David Olmos, Joanna Selfe, Ga?lle Pierron, Olivier Delattre, Zoe Walters & Janet Shipley. (2017) MicroRNA and gene co-expression networks characterize biological and clinical behavior of rhabdomyosarcomas. Cancer Letters 385, pages 251-260.
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Bo Jiang, Yanan Huo, Yangshun Gu & Jianyong Wang. (2016) The role of microRNAs in myopia. Graefe's Archive for Clinical and Experimental Ophthalmology 255:1, pages 7-13.
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Cong-Qiu ChuCong-Qiu Chu. 2017. Targeting the IL-17 Pathway in Inflammatory Disorders. Targeting the IL-17 Pathway in Inflammatory Disorders 55 99 .
Cameron P. Bracken, Hamish S. Scott & Gregory J. Goodall. (2016) A network-biology perspective of microRNA function and dysfunction in cancer. Nature Reviews Genetics 17:12, pages 719-732.
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Tomas Barta, Lucie Peskova & Ales Hampl. (2016) miRNAsong: a web-based tool for generation and testing of miRNA sponge constructs in silico. Scientific Reports 6:1.
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Samayita Das. (2016) Identification and targeting of microRNAs modulating acquired chemotherapy resistance in Triple negative breast cancer (TNBC): A better strategy to combat chemoresistance. Medical Hypotheses 96, pages 5-8.
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Yang Li, Xianfeng Zhang, Dawei Chen & Chengyuan Ma. (2015) Let-7a suppresses glioma cell proliferation and invasion through TGF-?/Smad3 signaling pathway by targeting HMGA2. Tumor Biology 37:6, pages 8107-8119.
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