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Review

Dry powder inhalers for optimal drug delivery

Pages 23-33 | Published online: 03 Mar 2005

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (12)

Marco Contoli, Sara Barile, Elena Nudo, Daniele Guastalla & Fulvio Braido. (2022) Exploring quality of life and satisfaction with treatment in asthmatic patients receiving dry powder inhalers: a multinational survey. Journal of Asthma 59:7, pages 1473-1483.
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Theerasuk Kawamatawong, Supattra Khiawwan & Prapaporn Pornsuriyasak. (2017) Peak inspiratory flow rate measurement by using In-Check DIAL for the different inhaler devices in elderly with obstructive airway diseases. Journal of Asthma and Allergy 10, pages 17-21.
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Vicky Chang, Emma L. Gray & Paul S. Thomas. (2016) Phamacology of fluticasone furoate and vilanterol trifenatate combination therapy for asthma. Expert Review of Respiratory Medicine 10:10, pages 1069-1078.
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Emma L. Gray, Vicky Chang & Paul S. Thomas. (2016) Fluticasone furoate and vilanterol trifenatate combination therapy for the treatment of asthma. Expert Review of Respiratory Medicine 10:8, pages 839-847.
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Basma M Ibrahim, Michael D Tsifansky, Yan Yang & Yoon Yeo. (2011) Challenges and advances in the development of inhalable drug formulations for cystic fibrosis lung disease. Expert Opinion on Drug Delivery 8:4, pages 451-466.
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Fadi Eskandar, Morgane Lejeune & Stephen Edge. (2011) Low powder mass filling of dry powder inhalation formulations. Drug Development and Industrial Pharmacy 37:1, pages 24-32.
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Zhen Xu, HeidiM. Mansour & AnthonyJ. Hickey. (2011) Particle Interactions in Dry Powder Inhaler Unit Processes: A Review. Journal of Adhesion Science and Technology 25:4-5, pages 451-482.
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Christian Friebel & Hartwig Steckel. (2010) Single-use disposable dry powder inhalers for pulmonary drug delivery. Expert Opinion on Drug Delivery 7:12, pages 1359-1372.
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Richard Pavkov, Stefan Mueller, Katrin Fiebich, Dilraj Singh, Frank Stowasser, Giovanni Pignatelli, Benoît Walter, Dominik Ziegler, Mukul Dalvi, Juergen Dederichs & Ilse Rietveld. (2010) Characteristics of a capsule based dry powder inhaler for the delivery of indacaterol. Current Medical Research and Opinion 26:11, pages 2527-2533.
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Satomi Onoue, Shingen Misaka, Yohei Kawabata & Shizuo Yamada. (2009) New treatments for chronic obstructive pulmonary disease and viable formulation/device options for inhalation therapy. Expert Opinion on Drug Delivery 6:8, pages 793-811.
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Ambikanandan Misra, Kaustubh Jinturkar, Deepa Patel, Jigar Lalani & Mahavir Chougule. (2009) Recent advances in liposomal dry powder formulations: preparation and evaluation. Expert Opinion on Drug Delivery 6:1, pages 71-89.
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Satomi Onoue, Naofumi Hashimoto & Shizuo Yamada. (2008) Dry powder inhalation systems for pulmonary delivery of therapeutic peptides and proteins. Expert Opinion on Therapeutic Patents 18:4, pages 429-442.
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Articles from other publishers (46)

Basanth Babu Eedara, Rakesh Bastola & Shyamal C. Das. (2022) Dissolution and Absorption of Inhaled Drug Particles in the Lungs. Pharmaceutics 14:12, pages 2667.
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Nashwa El-Gendy, Craig M. Bertha, Mohammed Abd El-Shafy, Dhaval K. Gaglani, Andrew Babiskin, Elizabeth Bielski, Susan Boc, Sneha Dhapare, Lanyan Fang, Katharine Feibus, Anubhav Kaviratna, Bing V. Li, Markham C. Luke, Tian Ma, Bryan Newman, Michael Spagnola, Ross L. Walenga & Liang Zhao. (2022) Scientific and regulatory activities initiated by the U.S. food and drug administration to foster approvals of generic dry powder inhalers: Quality perspective. Advanced Drug Delivery Reviews 189, pages 114519.
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Yang Geng, Lingying Zhao & S. Dee Jepsen. (2022) Designing a grain dust simulator for dusty environments in typical grain bins in the Midwestern United States. Biosystems Engineering 220, pages 203-213.
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Yuqing Ye, Ying Ma & Jesse Zhu. (2022) The future of dry powder inhaled therapy: Promising or discouraging for systemic disorders?. International Journal of Pharmaceutics 614, pages 121457.
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Krishna Sunkara, Meenu Mehta, Saurabh Satija, Daljeet Singh Dhanjal, Parvarish Sharma, Shakti D. Shukla, Madhur Shastri, Flavia C. Zacconi, Kamal Dua & Venkata Sita Rama Raju Allam. 2022. Advanced Drug Delivery Strategies for Targeting Chronic Inflammatory Lung Diseases. Advanced Drug Delivery Strategies for Targeting Chronic Inflammatory Lung Diseases 1 24 .
A. V. BadarinathS A SreenivasM. Suresh Babu. (2021) REVIEW ON DRY POWDER INHALERS: CURRENT ADVANCES AND LIMITATIONS. PARIPEX INDIAN JOURNAL OF RESEARCH, pages 63-67.
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Hana Douafer, Véronique Andrieu & Jean Michel Brunel. (2020) Scope and limitations on aerosol drug delivery for the treatment of infectious respiratory diseases. Journal of Controlled Release 325, pages 276-292.
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F. Lavorini, A. Bianco, F. Blasi, F. Braido, A.G. Corsico, F. Di Marco, A. Gentile, P.L. Paggiaro, V. Pegoraro, G. Pelaia, P. Rogliani, P. Santus, N. Scichilone, A. Soldi & G.W. Canonica. (2020) What drives inhaler prescription for asthma patients? Results from a real-life retrospective analysis. Respiratory Medicine 166, pages 105937.
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Hideyuki Sato, Aiko Tabata, Tatsuru Moritani, Tadahiko Morinaga, Takahiro Mizumoto, Yoshiki Seto & Satomi Onoue. (2020) Design and Characterizations of Inhalable Poly(lactic-co-glycolic acid) Microspheres Prepared by the Fine Droplet Drying Process for a Sustained Effect of Salmon Calcitonin. Molecules 25:6, pages 1311.
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Takashi Iwanaga, Yuji Tohda, Shuhei Nakamura & Yasunori Suga. (2019) The Respimat® Soft Mist Inhaler: Implications of Drug Delivery Characteristics for Patients. Clinical Drug Investigation 39:11, pages 1021-1030.
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M. Mohammadian & O. Pourmehran. (2018) CFPD simulation of magnetic drug delivery to a human lung using an SAW nebulizer. Biomechanics and Modeling in Mechanobiology 18:3, pages 547-562.
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Akshay Chandel, Amit K. Goyal, Goutam Ghosh & Goutam Rath. (2019) Recent advances in aerosolised drug delivery. Biomedicine & Pharmacotherapy 112, pages 108601.
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Dong-Xiao Hong, Yu-Long Yun, Yi-Xin Guan & Shan-Jing Yao. (2018) Preparation of micrometric powders of parathyroid hormone (PTH1–34)-loaded chitosan oligosaccharide by supercritical fluid assisted atomization. International Journal of Pharmaceutics 545:1-2, pages 389-394.
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Federico Lavorini, Massimo Pistolesi & Omar S. Usmani. (2017) Recent advances in capsule-based dry powder inhaler technology. Multidisciplinary Respiratory Medicine 12:1.
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A.G. Ogienko, E.G. Bogdanova, N.A. Trofimov, S.A. Myz, A.A. Ogienko, B.A. Kolesov, A.S. Yunoshev, N.V. Zubikov, A.Yu. Manakov, V.V. Boldyrev & E.V. Boldyreva. (2017) Large porous particles for respiratory drug delivery. Glycine-based formulations. European Journal of Pharmaceutical Sciences 110, pages 148-156.
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Morteza Yousefi, Oveis Pourmehran, Mofid Gorji-Bandpy, Kiao Inthavong, Leslie Yeo & Jiyuan Tu. (2017) CFD simulation of aerosol delivery to a human lung via surface acoustic wave nebulization. Biomechanics and Modeling in Mechanobiology 16:6, pages 2035-2050.
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Marta Silva, Ana Silva, Javier Fernandez-Lodeiro, Teresa Casimiro, Carlos Lodeiro & Ana Aguiar-Ricardo. (2017) Supercritical CO2-Assisted Spray Drying of Strawberry-Like Gold-Coated Magnetite Nanocomposites in Chitosan Powders for Inhalation. Materials 10:1, pages 74.
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Amit K. Goyal, Tarun Garg, Sourav Bhandari & Goutam Rath. 2017. Nanostructures for Drug Delivery. Nanostructures for Drug Delivery 669 695 .
Thaigarajan Parumasivam, Rachel Yoon Kyung Chang, Sharif Abdelghany, Tian Tian Ye, Warwick John Britton & Hak-Kim Chan. (2016) Dry powder inhalable formulations for anti-tubercular therapy. Advanced Drug Delivery Reviews 102, pages 83-101.
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Jung Yeon Lee, Kwang Ha Yoo, Deog Kyeom Kim, Sang-Ha Kim, Tae-Eun Kim, Tae-Hyung Kim, Chin Kook Rhee, Yong Bum Park, Hyoung Kyu Yoon & Ho-Kee Yum. (2016) Effects of Educational Interventions for Chronic Airway Disease on Primary Care. Journal of Korean Medical Science 31:7, pages 1069.
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Mithun Varghese Vadakkan, S.S. Binil Raj, Chandrasekharan C. Kartha & G.S. Vinod Kumar. (2015) Cationic, amphiphilic dextran nanomicellar clusters as an excipient for dry powder inhaler formulation. Acta Biomaterialia 23, pages 172-188.
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Eva Faulhammer, Marlies Fink, Marcos Llusa, Simon M. Lawrence, Stefano Biserni, Vittorio Calzolari & Johannes G. Khinast. (2014) Low-dose capsule filling of inhalation products: Critical material attributes and process parameters. International Journal of Pharmaceutics 473:1-2, pages 617-626.
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Melanie A Crane, Christine R Jenkins, Dianne P Goeman & Jo A Douglass. (2014) Inhaler device technique can be improved in older adults through tailored education: findings from a randomised controlled trial. npj Primary Care Respiratory Medicine 24:1.
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Huaidong LiYuanyuan ChenZhaorui ZhangXiaoxuan DongGuogang ZhangHui Zhang. (2014) Handling of Diskus Dry Powder Inhaler in Chinese Chronic Obstructive Pulmonary Disease Patients. Journal of Aerosol Medicine and Pulmonary Drug Delivery 27:3, pages 219-227.
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Olof Selroos. (2014) Dry-powder inhalers in acute asthma. Therapeutic Delivery 5:1, pages 69-81.
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David Young, Lee Wood, Dilraj Singh & Juergen Dederichs. 2014. Indacaterol. Indacaterol 117 128 .
Stephen P. Newman. 2013. Drug Delivery Applications of Noninvasive Imaging. Drug Delivery Applications of Noninvasive Imaging 333 366 .
Akira Tsuda, Frank S. Henry & James P. Butler. 2011. Comprehensive Physiology. Comprehensive Physiology 1437 1471 .
Joaquin Sanchis, Chris Corrigan, Mark L. Levy & Jose L. Viejo. (2013) Inhaler devices – From theory to practice. Respiratory Medicine 107:4, pages 495-502.
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Flore Depreter, Gabrielle Pilcer & Karim Amighi. (2013) Inhaled proteins: Challenges and perspectives. International Journal of Pharmaceutics 447:1-2, pages 251-280.
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S. Stegemann, S. Kopp, G. Borchard, V.P. Shah, S. Senel, R. Dubey, N. Urbanetz, M. Cittero, A. Schoubben, C. Hippchen, D. Cade, A. Fuglsang, J. Morais, L. Borgström, F. Farshi, K.-H. Seyfang, R. Hermann, A. van de Putte, I. Klebovich & A. Hincal. (2013) Developing and advancing dry powder inhalation towards enhanced therapeutics. European Journal of Pharmaceutical Sciences 48:1-2, pages 181-194.
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Leslie Y. Yeo, Hsueh-Chia Chang, Peggy P. Y. Chan & James R. Friend. (2011) Microfluidic Devices for Bioapplications. Small 7:1, pages 12-48.
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Parthiban Selvam, Doug McNair, Randall Truman & Hugh D.C. Smyth. (2010) A novel dry powder inhaler: Effect of device design on dispersion performance. International Journal of Pharmaceutics 401:1-2, pages 1-6.
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Aileen Gibbons, Noel G. McElvaney & Sally-Ann Cryan. (2010) A Dry Powder Formulation of Liposome-Encapsulated Recombinant Secretory Leukocyte Protease Inhibitor (rSLPI) for Inhalation: Preparation and Characterisation. AAPS PharmSciTech 11:3, pages 1411-1421.
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Zhen Xu, Heidi M. Mansour, Tako Mulder, Richard McLean, John Langridge & Anthony J. Hickey. (2010) Dry Powder Aerosols Generated by Standardized Entrainment Tubes From Drug Blends With Lactose Monohydrate: 1. Albuterol Sulfate and Disodium Cromoglycate. Journal of Pharmaceutical Sciences 99:8, pages 3398-3414.
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Zhen Xu, Heidi M. Mansour, Tako Mulder, Richard McLean, John Langridge & Anthony J. Hickey. (2010) Heterogeneous Particle Deaggregation and Its Implication for Therapeutic Aerosol Performance. Journal of Pharmaceutical Sciences 99:8, pages 3442-3461.
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Basma M. Ibrahim, Seoung Wook Jun, Mee Yong Lee, Soo Hyung Kang & Yoon Yeo. (2010) Development of inhalable dry powder formulation of basic fibroblast growth factor. International Journal of Pharmaceutics 385:1-2, pages 66-72.
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Marcus S. Shaker, Carrie Mohila, Joseph Schwartzman & Deborah Zuaro. (2009) MOLD OVERGROWTH ON A DRY POWDER INHALER DURING ROUTINE TREATMENT OF PERSISTENT ASTHMA. Annals of Allergy, Asthma & Immunology 102:3, pages 256.
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Chikamasa Yamashita. (2009) Development of Otsuka dry powder inhalation system using technology of freeze-drying. Drug Delivery System 24:5, pages 468-476.
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Gaurang Patel, Mahavir Chougule, Mandip Singh & Ambikanandan Misra. 2009. Liposomes, Part F. Liposomes, Part F 167 191 .
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Satomi Onoue, Shizuo Yamada & Takehiko Yajima. (2007) Bioactive analogues and drug delivery systems of vasoactive intestinal peptide (VIP) for the treatment of asthma/COPD. Peptides 28:9, pages 1640-1650.
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Robert A. Stockley, Stephen I. Rennard, Klaus Rabe & Bartolome CelliStephen P. Newman. 2007. Chronic Obstructive Pulmonary Disease. Chronic Obstructive Pulmonary Disease 481 498 .
Thomas E. Gill, Ted M. Zobeck & John E. Stout. (2006) Technologies for laboratory generation of dust from geological materials. Journal of Hazardous Materials 132:1, pages 1-13.
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Chikamasa Yamashita. (2006) The present state and future of dry powder inhalation system. Drug Delivery System 21:4, pages 417-425.
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Hiroyuki Ohbayashi. (2005) The Clinical Evaluation of the Acceptance of Fluticasone Propionate Diskus® by Older Japanese Patients with Bronchial Asthma. Allergology International 54:3, pages 411-418.
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