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Review

Poxvirus vaccines for cancer and HIV therapy

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Pages 575-588 | Published online: 03 Mar 2005

Keep up to date with the latest research on this topic with citation updates for this article.

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Douglas G McNeel, Yu-Hui Chen, James L Gulley, Alexander J Dwyer, Ravi A Madan, Michael A Carducci & Robert S DiPaola. (2015) Randomized phase II trial of docetaxel with or without PSA-TRICOM vaccine in patients with castrate-resistant metastatic prostate cancer: A trial of the ECOG-ACRIN cancer research group (E1809). Human Vaccines & Immunotherapeutics 11:10, pages 2469-2474.
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Erica Jackson & Hatem Soliman. (2012) Realizing the promise of breast cancer vaccines. Vaccine: Development and Therapy 2, pages 35-41.
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James L Gulley, Ravi A Madan, Kwong-Yok Tsang, Philip M Arlen, Kevin Camphausen, Mahsa Mohebtash, Mitchell Kamrava, Jeffrey Schlom & Deborah Citrin. (2011) A pilot safety trial investigating a vector-based vaccine targeting carcinoembryonic antigen in combination with radiotherapy in patients with gastrointestinal malignancies metastatic to the liver. Expert Opinion on Biological Therapy 11:11, pages 1409-1418.
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Ravi A Madan, Jeanny B Aragon-Ching, James L Gulley & William L Dahut. (2011) From clinical trials to clinical practice: therapeutic cancer vaccines for the treatment of prostate cancer. Expert Review of Vaccines 10:6, pages 743-753.
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Ravi A Madan & James L Gulley. (2011) Sipuleucel-T: harbinger of a new age of therapeutics for prostate cancer. Expert Review of Vaccines 10:2, pages 141-150.
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Mudita Pincha, Bala Sai Sundarasetty & Renata Stripecke. (2010) Lentiviral vectors for immunization: an inflammatory field. Expert Review of Vaccines 9:3, pages 309-321.
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Ravi A Madan, Mahsa Mohebtash, Jeffrey Schlom & James L Gulley. (2010) Therapeutic vaccines in metastatic castration-resistant prostate cancer: principles in clinical trial design. Expert Opinion on Biological Therapy 10:1, pages 19-28.
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Ravi A Madan, Philip M Arlen, Mahsa Mohebtash, James W Hodge & James L Gulley. (2009) Prostvac-VF: a vector-based vaccine targeting PSA in prostate cancer. Expert Opinion on Investigational Drugs 18:7, pages 1001-1011.
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Ravi A Madan, Philip M Arlen & James L Gulley. (2007) PANVAC™-VF: poxviral-based vaccine therapy targeting CEA and MUC1 in carcinoma. Expert Opinion on Biological Therapy 7:4, pages 543-554.
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Miriam E Mossoba & Jeffrey A Medin. (2006) Cancer immunotherapy using virally transduced dendritic cells: animal studies and human clinical trials. Expert Review of Vaccines 5:5, pages 717-732.
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Christian A Petrulio & Howard L Kaufman. (2006) Development of the PANVAC™-VF vaccine for pancreatic cancer. Expert Review of Vaccines 5:1, pages 9-19.
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Articles from other publishers (23)

Chiara Focaccetti, Monica Benvenuto, Sara Ciuffa, Sara Fazi, Manuel Scimeca, Alessandra Nardi, Martino Tony Miele, Andrea Battisti, Elena Bonanno, Andrea Modesti, Laura Masuelli & Roberto Bei. (2020) Curcumin Enhances the Antitumoral Effect Induced by the Recombinant Vaccinia Neu Vaccine (rV-neuT) in Mice with Transplanted Salivary Gland Carcinoma Cells. Nutrients 12:5, pages 1417.
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Shivani Handa, Bandhul Hans, Shokhi Goel, Hafis O. Bashorun, Zach Dovey & Ashutosh Tewari. (2020) Immunotherapy in prostate cancer: current state and future perspectives. Therapeutic Advances in Urology 12, pages 175628722095140.
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Juan J. Rojas, Padma Sampath, Braulio Bonilla, Alexandra Ashley, Weizhou Hou, Daniel Byrd & Steve H. Thorne. (2016) Manipulating TLR Signaling Increases the Anti-tumor T Cell Response Induced by Viral Cancer Therapies. Cell Reports 15:2, pages 264-273.
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Laura Masuelli, Massimo Fantini, Monica Benvenuto, Pamela Sacchetti, Maria Gabriella Giganti, Ilaria Tresoldi, Paolo Lido, Florigio Lista, Federica Cavallo, Patrizia Nanni, Jeffrey Schlom, Andrea Modesti & Roberto Bei. (2014) Intratumoral delivery of recombinant vaccinia virus encoding for ErbB2/Neu inhibits the growth of salivary gland carcinoma cells. Journal of Translational Medicine 12:1.
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Ravi A. Madan, Theresa A. Ferrara & James L. Gulley. 2014. Handbook of Anticancer Pharmacokinetics and Pharmacodynamics. Handbook of Anticancer Pharmacokinetics and Pharmacodynamics 553 568 .
R B Kennedy, A L Oberg, I G Ovsyannikova, I H Haralambieva, D Grill & G A Poland. (2013) Transcriptomic profiles of high and low antibody responders to smallpox vaccine. Genes & Immunity 14:5, pages 277-285.
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Ravi A. Madan, James L. Gulley & Philip W. Kantoff. (2013) Demystifying Immunotherapy in Prostate Cancer. The Cancer Journal 19:1, pages 50-58.
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Felicia Roscoe, Ren-Huan Xu & Luis J. Sigal. (2012) Characterization of Ectromelia Virus Deficient in EVM036 , the Homolog of Vaccinia virus F13L , and Its Application for Rapid Generation of Recombinant Viruses . Journal of Virology 86:24, pages 13501-13507.
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Marijo Bilusic & Ravi A. Madan. (2012) Therapeutic Cancer Vaccines. American Journal of Therapeutics 19:6, pages e172-e181.
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Mahsa Mohebtash, Kwong-Yok Tsang, Ravi A. Madan, Ngar-Yee Huen, Diane J. Poole, Caroline Jochems, Jacquin Jones, Theresa Ferrara, Christopher R. Heery, Philip M. Arlen, Seth M. Steinberg, Mary Pazdur, Myrna Rauckhorst, Elizabeth C. Jones, William L. Dahut, Jeffrey Schlom & James L. Gulley. (2011) A Pilot Study of MUC-1/CEA/TRICOM Poxviral-Based Vaccine in Patients with Metastatic Breast and Ovarian Cancer. Clinical Cancer Research 17:22, pages 7164-7173.
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Ravi A. Madan & James L. Gulley. (2010) The Current and Emerging Role of Immunotherapy in Prostate Cancer. Clinical Genitourinary Cancer 8:1, pages 10-16.
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Laura Masuelli, Laura Marzocchella, Chiara Focaccetti, Florigio Lista, Alessandra Nardi, Antonio Scardino, Maurizio Mattei, Mario Turriziani, Mauro Modesti, Guido Forni, Jeffrey Schlom, Andrea Modesti & Roberto Bei. (2010) Local delivery of recombinant vaccinia virus encoding for neu counteracts growth of mammary tumors more efficiently than systemic delivery in neu transgenic mice. Cancer Immunology, Immunotherapy 59:8, pages 1247-1258.
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Ravi A. Madan, James L. Gulley, Jackie Celestin, Philip M. Arlen & Jeffrey Schlom. 2010. Drug Management of Prostate Cancer. Drug Management of Prostate Cancer 305 319 .
David H. Kirn & Steve H. Thorne. (2009) Targeted and armed oncolytic poxviruses: a novel multi-mechanistic therapeutic class for cancer. Nature Reviews Cancer 9:1, pages 64-71.
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Ravi A. Madan, James L. Gulley, Jeffrey Schlom, Seth M. Steinberg, David J. Liewehr, William L. Dahut & Philip M. Arlen. (2008) Analysis of Overall Survival in Patients with Nonmetastatic Castration-Resistant Prostate Cancer Treated with Vaccine, Nilutamide, and Combination Therapy. Clinical Cancer Research 14:14, pages 4526-4531.
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Anna Ohradanova, Daniela Vullo, Juraj Kopacek, Claudia Temperini, Tatiana Betakova, Silvia Pastorekova, Jaromir Pastorek & Claudiu T. Supuran. (2007) Reconstitution of carbonic anhydrase activity of the cell-surface-binding protein of vaccinia virus. Biochemical Journal 407:1, pages 61-67.
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S Yang, Z S Guo, M E O'Malley, X Yin, H J Zeh & D L Bartlett. (2007) A new recombinant vaccinia with targeted deletion of three viral genes: its safety and efficacy as an oncolytic virus. Gene Therapy 14:8, pages 638-647.
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Kevin P. NishimotoAmanda K. LaustKehui WangKurt I. KamrudBolyn HubbyJonathan F. SmithEdward L. Nelson. (2007) Restricted and Selective Tropism of a Venezuelan Equine Encephalitis Virus-Derived Replicon Vector for Human Dendritic Cells. Viral Immunology 20:1, pages 88-104.
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E. R. Tulman, G. Delhon, C. L. Afonso, Z. Lu, L. Zsak, N. T. Sandybaev, U. Z. Kerembekova, V. L. Zaitsev, G. F. Kutish & D. L. Rock. (2006) Genome of Horsepox Virus. Journal of Virology 80:18, pages 9244-9258.
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Z. Sheng Guo, Arpana Naik, Mark E. O'Malley, Petar Popovic, Richard Demarco, Yun Hu, Xiaoyu Yin, Shuting Yang, Herbert J. Zeh, Bernard Moss, Michael T. Lotze & David L. Bartlett. (2005) The Enhanced Tumor Selectivity of an Oncolytic Vaccinia Lacking the Host Range and Antiapoptosis Genes SPI-1 and SPI-2 . Cancer Research 65:21, pages 9991-9998.
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C. M. Britten & U. Sahin. (2005) Impfstrategien zur Prävention oder Therapie von TumorenVaccination strategies for the prevention and therapy of cancer. Der Onkologe 11:5, pages 502-513.
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Grant McFadden. (2005) Poxvirus tropism. Nature Reviews Microbiology 3:3, pages 201-213.
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J.B. Johnston, Steven H. Nazarian, Renato Natale & Grant McFadden. (2005) Myxoma virus infection of primary human fibroblasts varies with cellular age and is regulated by host interferon responses. Virology 332:1, pages 235-248.
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