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Expert Opinion on Biological Therapy Volume 4, 2004 - Issue 4
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Review

Overcoming antigenic diversity and improving vaccines using DNA shuffling and screening technologies

Christopher P Locher Maxygen, Inc., Division of Infectious Diseases, Maxygen, Inc., 200 Penobscot Drive, Redwood City, CA 94063, USA. [email protected]
,
Volker Heinrichs Maxygen, Inc., Division of Infectious Diseases, Maxygen, Inc., 200 Penobscot Drive, Redwood City, CA 94063, USA
,
Doris Apt Maxygen, Inc., Division of Immunotherapeutics, Maxygen, Inc., 200 Penobscot Drive, Redwood City, CA 94063, USA
&
Robert G Whalen Maxygen, Inc., Division of Immunotherapeutics, Maxygen, Inc., 200 Penobscot Drive, Redwood City, CA 94063, USA
Pages 589-597 | Published online: 03 Mar 2005

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Martin Braddock. (2007) 11th Annual Inflammatory and Immune Diseases Drug Discovery and Development Summit. Expert Opinion on Investigational Drugs 16:6, pages 909-917.
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Articles from other publishers (5)

Sean X. Du, Rebecca J. Idiart, Ellaine B. Mariano, Helen Chen, Peifeng Jiang, Li Xu, Kristin M. Ostrow, Terri Wrin, Pham Phung, James M. Binley, Christos J. Petropoulos, John A. Ballantyne & Robert G. Whalen. (2009) Effect of trimerization motifs on quaternary structure, antigenicity, and immunogenicity of a noncleavable HIV-1 gp140 envelope glycoprotein. Virology 395:1, pages 33-44.
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Lesley C. Dupuy, Christopher P. Locher, Madan Paidhungat, Michelle J. Richards, Cathleen M. Lind, Russell Bakken, Michael D. Parker, Robert G. Whalen & Connie S. Schmaljohn. (2009) Directed molecular evolution improves the immunogenicity and protective efficacy of a Venezuelan equine encephalitis virus DNA vaccine. Vaccine 27:31, pages 4152-4160.
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Sabine C. Stebel, Annette Gaida, Katja M. Arndt & Kristian M. Müller. 2008. Molecular Biomethods Handbook. Molecular Biomethods Handbook 631 656 .
Tuck Seng Wong, Danilo Roccatano & Ulrich Schwaneberg. (2007) Steering directed protein evolution: strategies to manage combinatorial complexity of mutant libraries. Environmental Microbiology 9:11, pages 2645-2659.
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Ling Yuan, Itzhak Kurek, James English & Robert Keenan. (2005) Laboratory-Directed Protein Evolution. Microbiology and Molecular Biology Reviews 69:3, pages 373-392.
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