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Review

Use of CpG oligodeoxynucleotides as immunoprotective agents

Pages 937-946 | Published online: 23 Feb 2005

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Songhui Li, Wenfeng Zhao, Lei Xia, Lingyi Kong & Lei Yang. (2023) How Long Will It Take to Launch an Effective Helicobacter pylori Vaccine for Humans?. Infection and Drug Resistance 16, pages 3787-3805.
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Jinzhu Ma, Beiyan Wang, Liquan Yu, Baifen Song, Yongzhong Yu, Shuangshuang Wu, Yazun Dong, Zhanbo Zhu & Yudong Cui. (2020) The novel combinations of CTB, CpG, and aluminum hydroxide significantly enhanced the immunogenicity of clumping factor A 221-550 of Staphylococcus aureus. Bioscience, Biotechnology, and Biochemistry 84:9, pages 1846-1855.
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Heather L. Wilson, Arshud Dar, Scott K. Napper, A. Marianela Lopez, Lorne A. Babiuk & George K. Mutwiri. (2006) Immune Mechanisms and Therapeutic Potential of CpG Oligodeoxynucleotides. International Reviews of Immunology 25:3-4, pages 183-213.
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Jörg Vollmer. (2006) TLR9 in Health and Disease. International Reviews of Immunology 25:3-4, pages 155-181.
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Jörg Vollmer. (2005) Progress in drug development of immunostimulatory CpG oligodeoxynucleotide ligands for TLR9. Expert Opinion on Biological Therapy 5:5, pages 673-682.
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Nelson S Yew & Seng H Cheng. (2004) Reducing the immunostimulatory activity of CpG-containing plasmid DNA vectors for non-viral gene therapy. Expert Opinion on Drug Delivery 1:1, pages 115-125.
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Jinzhu Ma, Wei Liu, Beiyan Wang, Simiao Yu, Liquan Yu, Baifen Song, Yongzhong Yu, Zhanbo Zhu & Yudong Cui. (2021) Als3‐Th‐cell‐epitopes plus the novel combined adjuvants of CpG, MDP, and FIA synergistically enhanced the immune response of recombinant TRAP derived from Staphylococcus aureus in mice . Immunity, Inflammation and Disease 9:3, pages 971-983.
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Seth G Thacker, Ian L. McWilliams, Beatrice Bonnet, Lydia Halie, Serge Beaucage, Swaksha Rachuri, Ranadhir Dey, Robert Duncan, Farrokh Modabber, Stephen Robinson, Graeme Bilbe, Byron Arana & Daniela Verthelyi. (2020) CpG ODN D35 improves the response to abbreviated low-dose pentavalent antimonial treatment in non-human primate model of cutaneous leishmaniasis. PLOS Neglected Tropical Diseases 14:2, pages e0008050.
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Mohanraj Manangeeswaran, Aaron P. Lewkowicz, Tomer Israely, Derek D.C. Ireland & Daniela Verthelyi. (2020) CpG Oligonucleotides Protect Mice From Alphavirus Encephalitis: Role of NK Cells, Interferons, and TNF. Frontiers in Immunology 11.
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Krisztina Fehér. (2019) Single Stranded DNA Immune Modulators with Unmethylated CpG Motifs: Structure and Molecular Recognition by Toll-Like Receptor 9. Current Protein & Peptide Science 20:11, pages 1060-1068.
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Sakineh Pirahmadi, Sedigheh Zakeri, Akram A. Mehrizi, Navid D. Djadid, Abbas-Ali Raz & Jafar J. Sani. (2019) Combining Monophosphoryl Lipid A (MPL), CpG Oligodeoxynucleotide (ODN), and QS-21 Adjuvants Induces Strong and Persistent Functional Antibodies and T Cell Responses against Cell-Traversal Protein for Ookinetes and Sporozoites (CelTOS) of Plasmodium falciparum in BALB/c Mice. Infection and Immunity 87:6.
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Jinzhu Ma, Liquan Yu, Baifen Song, Yongzhong Yu, Shaoduo Zhang, Yuhua Wei, Zhijun Wu, Di Yao, Wei Yu, Zhanbo Zhu & Yudong Cui. (2018) The double adjuvants LTB and CpG significantly enhanced the immuno-protective effects of recombinant GIT derived from Staphylococcus aureus and Streptococcus in mice. Journal of Medical Microbiology 67:3, pages 432-440.
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