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Expert Opinion on Biological Therapy Volume 5, 2005 - Issue 1
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Review

Intratumoural administration of dendritic cells: hostile environment and help by gene therapy

Eduardo Huarte University of Navarra School of Medicine, Gene Therapy Unit, Centro Investigación Médica Aplicada (CIMA), Avda/Pio XII,55, 31080 Pamplona, Spain. [email protected]
,
Iñigo Tirapu University of Navarra School of Medicine, Gene Therapy Unit, Centro Investigación Médica Aplicada (CIMA), Avda/Pio XII,55, 31080 Pamplona, Spain. [email protected]
,
Ainhoa Arina University of Navarra School of Medicine, Gene Therapy Unit, Centro Investigación Médica Aplicada (CIMA), Avda/Pio XII,55, 31080 Pamplona, Spain. [email protected]
,
María Vera University of Navarra School of Medicine, Gene Therapy Unit, Centro Investigación Médica Aplicada (CIMA), Avda/Pio XII,55, 31080 Pamplona, Spain. [email protected]
,
Carlos Alfaro University of Navarra School of Medicine, Gene Therapy Unit, Centro Investigación Médica Aplicada (CIMA), Avda/Pio XII,55, 31080 Pamplona, Spain. [email protected]
,
Oihana Murillo University of Navarra School of Medicine, Gene Therapy Unit, Centro Investigación Médica Aplicada (CIMA), Avda/Pio XII,55, 31080 Pamplona, Spain. [email protected]
,
Belén Palencia University of Navarra School of Medicine, Gene Therapy Unit, Centro Investigación Médica Aplicada (CIMA), Avda/Pio XII,55, 31080 Pamplona, Spain. [email protected]
,
Victoria Busto University of Navarra School of Medicine, Gene Therapy Unit, Centro Investigación Médica Aplicada (CIMA), Avda/Pio XII,55, 31080 Pamplona, Spain. [email protected]
,
Verónica Marín University of Navarra School of Medicine, Gene Therapy Unit, Centro Investigación Médica Aplicada (CIMA), Avda/Pio XII,55, 31080 Pamplona, Spain. [email protected]
,
Guillermo Mazzolini University of Navarra School of Medicine, Gene Therapy Unit, Centro Investigación Médica Aplicada (CIMA), Avda/Pio XII,55, 31080 Pamplona, Spain. [email protected]
&
Ignacio Melero University of Navarra School of Medicine, Gene Therapy Unit, Centro Investigación Médica Aplicada (CIMA), Avda/Pio XII,55, 31080 Pamplona, Spain. [email protected]
 show all
Pages 7-22 | Published online: 20 Apr 2005

Citations (9)

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Michael R Shurin, Melissa Gregory, John C Morris & Anatoli M Malyguine. (2010) Genetically modified dendritic cells in cancer immunotherapy: a better tomorrow?. Expert Opinion on Biological Therapy 10:11, pages 1539-1553.
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Articles from other publishers (8)

Ignacio Melero, Eduardo Castanon, Maite Alvarez, Stephane Champiat & Aurelien Marabelle. (2021) Intratumoural administration and tumour tissue targeting of cancer immunotherapies. Nature Reviews Clinical Oncology 18:9, pages 558-576.
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A.R. Sánchez-Paulete, A. Teijeira, F.J. Cueto, S. Garasa, J.L. Pérez-Gracia, A. Sánchez-Arráez, D. Sancho & I. Melero. (2017) Antigen cross-presentation and T-cell cross-priming in cancer immunology and immunotherapy. Annals of Oncology 28, pages xii44-xii55.
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Jacob Osterbur, Leslee Sprague, Maria Muccioli, Michelle Pate, Kristen Mansfield, John McGinty, Yihan Li, Yandi Li, Venktesh Shirure, Maria Cecilia Courreges & Fabian Benencia. (2013) Adhesion to substrates induces dendritic cell endothelization and decreases immunological response. Immunobiology 218:1, pages 64-75.
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Carlos Alfaro, Natalia Suárez, Ivan Martínez-Forero, Asís Palazón, Ana Rouzaut, Sarai Solano, Esperanza Feijoo, Alfonso Gúrpide, Elixabet Bolaños, Lorena Erro, Juan Dubrot, Sandra Hervás-Stubbs, Alvaro Gonzalez, Jose Luis Perez-Gracia & Ignacio Melero. (2011) Carcinoma-Derived Interleukin-8 Disorients Dendritic Cell Migration Without Impairing T-Cell Stimulation. PLoS ONE 6:3, pages e17922.
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Oihana Murillo, Juan Dubrot, Asís Palazón, Ainhoa Arina, Arantza Azpilikueta, Carlos Alfaro, Sarai Solano, María C. Ochoa, Carmen Berasain, Izaskun Gabari, José. L. Pérez‐Gracia, Pedro Berraondo, Sandra Hervás‐Stubbs & Ignacio Melero. (2009) In vivo depletion of DC impairs the anti‐tumor effect of agonistic anti‐CD137 mAb . European Journal of Immunology 39:9, pages 2424-2436.
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Alessandro Zerbini, Massimo Pilli, Francesco Fagnoni, Guido Pelosi, Maria Grazia Pizzi, Simona Schivazappa, Diletta Laccabue, Cristina Cavallo, Claudia Schianchi, Carlo Ferrari & Gabriele Missale. (2008) Increased Immunostimulatory Activity Conferred to Antigen-presenting Cells by Exposure to Antigen Extract From Hepatocellular Carcinoma After Radiofrequency Thermal Ablation. Journal of Immunotherapy 31:3, pages 271-282.
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Ainhoa Arina, Oihana Murillo, Sandra Hervás‐Stubbs, Arantza Azpilikueta, Juan Dubrot, Iñigo Tirapu, Eduardo Huarte, Carlos Alfaro, Jose L. Pérez‐Gracia, Gloria González‐Aseguinolaza, Pablo Sarobe, Juan J. Lasarte, Amanda Jamieson, Jesús Prieto, David H. Raulet & Ignacio Melero. (2007) The combined actions of NK and T lymphocytes are necessary to reject an EGFP+ mesenchymal tumor through mechanisms dependent on NKG2D and IFNγ. International Journal of Cancer 121:6, pages 1282-1295.
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Ignacio Melero, Ainhoa Arina, Oihana Murillo, Juan Dubrot, Carlos Alfaro, Jose L. Pérez-Gracia, Maurizio Bendandi & Sandra Hervás-Stubbs. (2006) Immunogenic Cell Death and Cross-Priming Are Reaching the Clinical Immunotherapy Arena. Clinical Cancer Research 12:8, pages 2385-2389.
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