Citations (101)
Keep up to date with the latest research on this topic with citation updates for this article.
Read on this site (5)
Zulmarie Perez Horta, Swetha Saseedhar, Alexander L. Rakhmilevich, Lakeesha Carmichael, Jacquelyn A. Hank, Margaret Boyden, Stephen D. Gillies & Paul M. Sondel. (2019) Human and murine IL2 receptors differentially respond to the human-IL2 component of immunocytokines. OncoImmunology 8:6.
Read now
Read now
Christian Klein, Inja Waldhauer, Valeria G. Nicolini, Anne Freimoser-Grundschober, Tapan Nayak, Danielle J. Vugts, Claire Dunn, Marije Bolijn, Jörg Benz, Martine Stihle, Sabine Lang, Michaele Roemmele, Thomas Hofer, Erwin van Puijenbroek, David Wittig, Samuel Moser, Oliver Ast, Peter Brünker, Ingo H. Gorr, Sebastian Neumann, Maria Cristina de Vera Mudry, Heather Hinton, Flavio Crameri, Jose Saro, Stefan Evers, Christian Gerdes, Marina Bacac, Guus van Dongen, Ekkehard Moessner & Pablo Umaña. (2017) Cergutuzumab amunaleukin (CEA-IL2v), a CEA-targeted IL-2 variant-based immunocytokine for combination cancer immunotherapy: Overcoming limitations of aldesleukin and conventional IL-2-based immunocytokines. OncoImmunology 6:3.
Read now
Read now
Gertrudis Rojas, Yanelys Cabrera Infante, Amaury Pupo & Tania Carmenate. (2014) Fine epitope specificity of antibodies against interleukin-2 explains their paradoxical immunomodulatory effects. mAbs 6:1, pages 273-285.
Read now
Read now
Samantha O Arnett, Jean-Luc Teillaud, Thierry Wurch, Janice M Reichert, Cameron Dunlop & Michael Huber. (2011) IBC's 21st Annual Antibody Engineering and 8th Annual Antibody Therapeutics International Conferences and 2010 Annual Meeting of The Antibody Society. mAbs 3:2, pages 133-152.
Read now
Read now
Patrycja J Lech & Stephen J Russell. (2010) Use of attenuated paramyxoviruses for cancer therapy. Expert Review of Vaccines 9:11, pages 1275-1302.
Read now
Read now
Articles from other publishers (96)
Luke M. Tomasovic, Kathy Liu, Derek VanDyke, Charina S. Fabilane & Jamie B. Spangler. (2023) Molecular Engineering of Interleukin-2 for Enhanced Therapeutic Activity in Autoimmune Diseases. BioDrugs.
Crossref
Crossref
Takashi Kei Kishimoto, Max Fournier, Alicia Michaud, Gina Rizzo, Christopher Roy, Teresa Capela, Natasha Nukolova, Ning Li, Liam Doyle, Fen-ni Fu, Derek VanDyke, Peter G. Traber, Jamie B. Spangler, Sheldon S. Leung & Petr O. Ilyinskii. (2023) Rapamycin nanoparticles increase the therapeutic window of engineered interleukin-2 and drive expansion of antigen-specific regulatory T cells for protection against autoimmune disease. Journal of Autoimmunity 140, pages 103125.
Crossref
Crossref
Nengqi Lin, Wei Yin, Heather Miller, Maria G. Byazrova, Andrés A. Herrada, Kamel Benlagha, Pamela Lee, Fei Guan, Jiahui Lei, Quan Gong, Youqing Yan, Alexander Filatov & Chaohong Liu. (2023) The role of regulatory T cells and follicular T helper cells in HBV infection. Frontiers in Immunology 14.
Crossref
Crossref
Sarah R. Tritsch, Abigail J. Porzucek, Arnold M. Schwartz, Abigale M. Proctor, Richard L. Amdur, Patricia S. Latham, Gary L. Simon, Christopher N. Mores & Aileen Y. Chang. (2023) Effects of rIL2/anti-IL2 antibody complex on chikungunya virus-induced chronic arthritis in a mouse model. Scientific Reports 13:1.
Crossref
Crossref
Alison McFarlane, Elizabeth Pohler & Ignacio Moraga. (2022) Molecular and cellular factors determining the functional pleiotropy of cytokines. The FEBS Journal 290:10, pages 2525-2552.
Crossref
Crossref
Sun-Wei Guo. (2023) Various types of adenomyosis and endometriosis: in search of optimal management. Fertility and Sterility 119:5, pages 711-726.
Crossref
Crossref
Yujia Peng, Yiran Tao, Ya Zhang, Jiaxing Wang, Jinliang Yang & Yuxi Wang. (2022)
CD25
: A potential tumor therapeutic target
. International Journal of Cancer 152:7, pages 1290-1303.
Crossref
Crossref
Xiaoxia Chi, Shahang Luo, Peng Ye, Wei-Lun Hwang, Jong-Ho Cha, Xiuwen Yan & Wen-Hao Yang. (2023) T-cell exhaustion and stemness in antitumor immunity: Characteristics, mechanisms, and implications. Frontiers in Immunology 14.
Crossref
Crossref
Albert J. Czaja. (2022) Advancing Biologic Therapy for Refractory Autoimmune Hepatitis. Digestive Diseases and Sciences 67:11, pages 4979-5005.
Crossref
Crossref
Merve Uslu, Esra Albayrak & Fatih Kocabaş. (2022) Competitive inhibition of IL-2/IL-2R has a dual effect on HSC ex vivo expansion and IL-2R (CD25) content. International Immunopharmacology 110, pages 109035.
Crossref
Crossref
Dasom Kim, Jin-Ho Park, Tae-Yoon Kim, Dong-Gun Kim, June-Ho Byun & Hak-Sung Kim. (2022) Enhanced half-life and antitumor activity of interleukin-15 through genetic fusion of a serum albumin-specific protein binder. International Journal of Pharmaceutics 625, pages 122059.
Crossref
Crossref
Andrea C. Pichler, Jennifer L. Cannons & Pamela L. Schwartzberg. (2022) The Road Less Taken: Less Appreciated Pathways for Manipulating CD8+ T Cell Exhaustion. Frontiers in Immunology 13.
Crossref
Crossref
Martin Klein, Barbara Misme‐Aucouturier, Marie‐Aude Cheminant, Marion De Carvalho, Marie Wauters, Olivier Tranquet, Antoine Magnan & Grégory Bouchaud. (2021) Engineering a safe monoclonal anti‐human IL‐2 that is effective in a murine model of food allergy and asthma. Allergy 77:3, pages 933-945.
Crossref
Crossref
Erin A. Holcomb & Weiping Zou. (2022) A forced marriage of IL-2 and PD-1 antibody nurtures tumor-infiltrating T cells. Journal of Clinical Investigation 132:3.
Crossref
Crossref
Ying Tang, Anne X.J. Zhang, Guangyu Chen, Yanheng Wu & Wenyi Gu. (2021) Prognostic and therapeutic TILs of cervical cancer—Current advances and future perspectives. Molecular Therapy - Oncolytics 22, pages 410-430.
Crossref
Crossref
Mohammad Raghibul Hasan, Bader Saud Alotaibi, Sultan F. Alnomasy & Khalid Umar Fakhri. 2021. Handbook of Research on Advancements in Cancer Therapeutics. Handbook of Research on Advancements in Cancer Therapeutics
1
41
.
Barbara Carreira, Rita C. Acúrcio, Ana I. Matos, Carina Peres, Sabina Pozzi, Daniella Vaskovich‐Koubi, Ron Kleiner, Mariana Bento, Ronit Satchi‐Fainaro & Helena F. Florindo. (2020) Nanomedicines as Multifunctional Modulators of Melanoma Immune Microenvironment. Advanced Therapeutics 4:1, pages 2000147.
Crossref
Crossref
Maite Alvarez, Cordelia Dunai, Lam T. Khuat, Ethan G. Aguilar, Isabel Barao & William J. Murphy. (2020) IL-2 and Anti-TGF-β Promote NK Cell Reconstitution and Anti-tumor Effects after Syngeneic Hematopoietic Stem Cell Transplantation. Cancers 12:11, pages 3189.
Crossref
Crossref
Ruihe Wu, Na Li, Xiangcong Zhao, Tingting Ding, Hongwei Xue, Chong Gao, Xiaofeng Li & Caihong Wang. (2020) Low-dose Interleukin-2: Biology and therapeutic prospects in rheumatoid arthritis. Autoimmunity Reviews 19:10, pages 102645.
Crossref
Crossref
Jian Qiao & Yang-Xin Fu. (2020) Cytokines that target immune killer cells against tumors. Cellular & Molecular Immunology 17:7, pages 722-727.
Crossref
Crossref
Jared E Lopes, Jan L Fisher, Heather L Flick, Chunhua Wang, Lei Sun, Marc S Ernstoff, Juan C Alvarez & Heather C Losey. (2020) ALKS 4230: a novel engineered IL-2 fusion protein with an improved cellular selectivity profile for cancer immunotherapy. Journal for ImmunoTherapy of Cancer 8:1, pages e000673.
Crossref
Crossref
Zhichen Sun, Zhenhua Ren, Kaiting Yang, Zhida Liu, Shuaishuai Cao, Sisi Deng, Lily Xu, Yong Liang, Jingya Guo, Yingjie Bian, Hairong Xu, Jiyun Shi, Fan Wang, Yang-Xin Fu & Hua Peng. (2019) A next-generation tumor-targeting IL-2 preferentially promotes tumor-infiltrating CD8+ T-cell response and effective tumor control. Nature Communications 10:1.
Crossref
Crossref
Le Xu, Xiaolei Song, Lili Su, Yong Zheng, Ru Li & Jian Sun. (2019) New therapeutic strategies based on IL-2 to modulate Treg cells for autoimmune diseases. International Immunopharmacology 72, pages 322-329.
Crossref
Crossref
Laura M. McLane, Mohamed S. Abdel-Hakeem & E. John Wherry. (2019) CD8 T Cell Exhaustion During Chronic Viral Infection and Cancer. Annual Review of Immunology 37:1, pages 457-495.
Crossref
Crossref
Lorenzo Mortara, Enrica Balza, Antonino Bruno, Alessandro Poggi, Paola Orecchia & Barbara Carnemolla. (2018) Anti-cancer Therapies Employing IL-2 Cytokine Tumor Targeting: Contribution of Innate, Adaptive and Immunosuppressive Cells in the Anti-tumor Efficacy. Frontiers in Immunology 9.
Crossref
Crossref
Zuqiang Liu, Yan Ge, Haiyan Wang, Congrong Ma, Mathilde Feist, Songguang Ju, Z. Sheng Guo & David L. Bartlett. (2018) Modifying the cancer-immune set point using vaccinia virus expressing re-designed interleukin-2. Nature Communications 9:1.
Crossref
Crossref
Jamie B. Spangler, Eleonora Trotta, Jakub Tomala, Ariana Peck, Tracy A. Young, Christina S. Savvides, Stephanie Silveria, Petra Votavova, Joshua Salafsky, Vijay S. Pande, Marek Kovar, Jeffrey A. Bluestone & K. Christopher Garcia. (2018) Engineering a Single-Agent Cytokine/Antibody Fusion That Selectively Expands Regulatory T Cells for Autoimmune Disease Therapy. The Journal of Immunology 201:7, pages 2094-2106.
Crossref
Crossref
Claire Gorby, Jonathan Martinez-Fabregas, Stephan Wilmes & Ignacio Moraga. (2018) Mapping Determinants of Cytokine Signaling via Protein Engineering. Frontiers in Immunology 9.
Crossref
Crossref
Stefan Heiler, Jonas Lötscher, Matthias Kreuzaler, Johanna Rolink & Antonius Rolink. (2018) Prophylactic and Therapeutic Effects of Interleukin-2 (IL-2)/Anti-IL-2 Complexes in Systemic Lupus Erythematosus-Like Chronic Graft-Versus-Host Disease. Frontiers in Immunology 9.
Crossref
Crossref
Suman Mitra & Warren J Leonard. (2018) Biology of IL-2 and its therapeutic modulation: Mechanisms and strategies. Journal of Leukocyte Biology 103:4, pages 643-655.
Crossref
Crossref
Hilde Cheroutre. (2018) Charles D. Surh, PhD: 1961–2017. Mucosal Immunology 11:2, pages 291-293.
Crossref
Crossref
Rakeeb Kureshi, Michelle Bahri & Jamie B Spangler. (2018) Reprogramming immune proteins as therapeutics using molecular engineering. Current Opinion in Chemical Engineering 19, pages 27-34.
Crossref
Crossref
Daniela Langenhorst, Paula Tabares, Tobias Gulde, Bryan R. Becklund, Susanne Berr, Charles D. Surh, Niklas Beyersdorf & Thomas Hünig. (2018) Self-Recognition Sensitizes Mouse and Human Regulatory T Cells to Low-Dose CD28 Superagonist Stimulation. Frontiers in Immunology 8.
Crossref
Crossref
Michael J. Flynn & John A. Hartley. (2017) The emerging role of anti-CD25 directed therapies as both immune modulators and targeted agents in cancer. British Journal of Haematology 179:1, pages 20-35.
Crossref
Crossref
Heather Freer, Julia M. Hillegas, Christine Wimer, Cynthia Baldwin, Joanna LaBresh & Bettina Wagner. (2017) A monoclonal antibody for detection of intracellular and secreted interleukin-2 in horses. Veterinary Immunology and Immunopathology 191, pages 30-35.
Crossref
Crossref
B. Bonnet, P.A. Vinot & B. Bellier. (2017) Cibles et immunoth?rapies innovantes dans le traitement de l?allergie alimentaire. Revue Fran?aise d'Allergologie 57:4, pages 327-336.
Crossref
Crossref
Alon Oyler-Yaniv, Jennifer Oyler-Yaniv, Benjamin M. Whitlock, Zhiduo Liu, Ronald N. Germain, Morgan Huse, Grégoire Altan-Bonnet & Oleg Krichevsky. (2017) A Tunable Diffusion-Consumption Mechanism of Cytokine Propagation Enables Plasticity in Cell-to-Cell Communication in the Immune System. Immunity 46:4, pages 609-620.
Crossref
Crossref
Pooja Dhupkar & Nancy Gordon. 2017. Immunotherapy. Immunotherapy
33
51
.
Xi Chen, Jin Xu, Qingcheng Guo, Lingfei Wang, Yun Yang, Huaizu Guo, Nana Gu, Dapeng Zhang, Weizhu Qian, Sheng Hou, Jing Li, Jianxin Dai, Yajun Guo & Hao Wang. (2016) Therapeutic efficacy of an anti-PD-L1 antibody based immunocytokine in a metastatic mouse model of colorectal cancer. Biochemical and Biophysical Research Communications 480:2, pages 160-165.
Crossref
Crossref
Kaitlin A. Read, Michael D. Powell, Paul W. McDonald & Kenneth J. Oestreich. (2016) IL-2, IL-7, and IL-15: Multistage regulators of CD4+ T helper cell differentiation. Experimental Hematology 44:9, pages 799-808.
Crossref
Crossref
Shirin Z. Birjandi, Vyacheslav Palchevskiy, Ying Ying Xue, Stefanie Nunez, Rita Kern, S. Sam Weigt, Joseph P. LynchIIIIII, Talal A. Chatila & John A. Belperio. (2016) CD4+CD25hiFoxp3+ Cells Exacerbate Bleomycin-Induced Pulmonary Fibrosis. The American Journal of Pathology 186:8, pages 2008-2020.
Crossref
Crossref
Sourabh Shukla & Nicole F Steinmetz. (2016) Emerging nanotechnologies for cancer immunotherapy. Experimental Biology and Medicine 241:10, pages 1116-1126.
Crossref
Crossref
Holly Bolton & Barbara Groth. (2016) Reconstitution of Lymphopaenic Mice with Regulatory and Conventional T cell Subsets. BIO-PROTOCOL 6:10.
Crossref
Crossref
Natalia Arenas-Ramirez & Onur Boyman. 2016. Compendium of Inflammatory Diseases. Compendium of Inflammatory Diseases
670
677
.
Natalia Arenas-Ramirez, Janine Woytschak & Onur Boyman. (2015) Interleukin-2: Biology, Design and Application. Trends in Immunology 36:12, pages 763-777.
Crossref
Crossref
Jamie B. Spangler, Jakub Tomala, Vincent C. Luca, Kevin M. Jude, Shen Dong, Aaron M. Ring, Petra Votavova, Marion Pepper, Marek Kovar & K. Christopher Garcia. (2015) Antibodies to Interleukin-2 Elicit Selective T Cell Subset Potentiation through Distinct Conformational Mechanisms. Immunity 42:5, pages 815-825.
Crossref
Crossref
Jamie B. SpanglerIgnacio MoragaJuan L. MendozaK. Christopher Garcia. (2015) Insights into Cytokine–Receptor Interactions from Cytokine Engineering. Annual Review of Immunology 33:1, pages 139-167.
Crossref
Crossref
Rodney A Rosalia, Natalia Arenas-Ramirez, Grégory Bouchaud, Miro E Raeber & Onur Boyman. (2014) Use of enhanced interleukin-2 formulations for improved immunotherapy against cancer. Current Opinion in Chemical Biology 23, pages 39-46.
Crossref
Crossref
Jason W.-L. Eng, Kathleen M. Kokolus, Chelsey B. Reed, Bonnie L. Hylander, Wen W. Ma & Elizabeth A. Repasky. (2014) A nervous tumor microenvironment: the impact of adrenergic stress on cancer cells, immunosuppression, and immunotherapeutic response. Cancer Immunology, Immunotherapy 63:11, pages 1115-1128.
Crossref
Crossref
Penelope A. Morel, James R. Faeder, William F. Hawse & Natasa Miskov-Zivanov. (2014) Modeling the T cell immune response: a fascinating challenge. Journal of Pharmacokinetics and Pharmacodynamics 41:5, pages 401-413.
Crossref
Crossref
Andrew L. Croxford, Paulina Kulig & Burkhard Becher. (2014) IL-12-and IL-23 in health and disease. Cytokine & Growth Factor Reviews 25:4, pages 415-421.
Crossref
Crossref
C.L. Liu, P. Ye, J. Lin, D. Djukovic & C.H. Miao. (2014) Long‐term tolerance to factor VIII is achieved by administration of interleukin‐2/interleukin‐2 monoclonal antibody complexes and low dosages of factor VIII. Journal of Thrombosis and Haemostasis 12:6, pages 921-931.
Crossref
Crossref
Dafne M?ller. (2013) Antibody?Cytokine Fusion Proteins for Cancer Immunotherapy: An Update on Recent Developments. BioDrugs 28:2, pages 123-131.
Crossref
Crossref
Natalia Arenas-Ramirez & Onur Boyman. 2015. Encyclopedia of Inflammatory Diseases. Encyclopedia of Inflammatory Diseases
1
9
.
Caspar Kühnöl, Monique Herbarth, Jürgen Föll, Martin S. Staege & Christof Kramm. (2013) CD137 stimulation and p38 MAPK inhibition improve reactivity in an in vitro model of glioblastoma immunotherapy. Cancer Immunology, Immunotherapy 62:12, pages 1797-1809.
Crossref
Crossref
Kevin R. Mott, Mandana Zandian, Sariah J. Allen & Homayon Ghiasi. (2013) Role of Interleukin-2 and Herpes Simplex Virus 1 in Central Nervous System Demyelination in Mice. Journal of Virology 87:22, pages 12102-12109.
Crossref
Crossref
Yaiza Diaz-de-Durana, Janet Lau, Deborah Knee, Christophe Filippi, Marco Londei, Peter McNamara, Marc Nasoff, Michael DiDonato, Richard Glynne & Ann E. Herman. (2013) IL-2 Immunotherapy Reveals Potential for Innate Beta Cell Regeneration in the Non-Obese Diabetic Mouse Model of Autoimmune Diabetes. PLoS ONE 8:10, pages e78483.
Crossref
Crossref
Myung-Gyu Kim, Tai Yeon Koo, Ji-Jing Yan, Eunwon Lee, Kyu Hyun Han, Jong Cheol Jeong, Han Ro, Beom Seok Kim, Sang-Kyung Jo, Kook Hwan Oh, Charles D. Surh, Curie Ahn & Jaeseok Yang. (2013) IL-2/Anti-IL-2 Complex Attenuates Renal Ischemia-Reperfusion Injury through Expansion of Regulatory T Cells. Journal of the American Society of Nephrology 24:10, pages 1529-1536.
Crossref
Crossref
Tamara Veiga-Parga, Sharvan Sehrawat & Barry T. Rouse. (2013) Role of regulatory T cells during virus infection. Immunological Reviews 255:1, pages 182-196.
Crossref
Crossref
S. Wang, H. T. Li, Y. H. Liu, Y. Z. Zhu, W. H. Wang, Y. X. An & L. G. Miao. (2013) Expression, Identification and Characterize of CD25-Binding Epitope Modified Human IL-2 in Pichia pastoris. Indian Journal of Microbiology 53:3, pages 283-287.
Crossref
Crossref
Rodrigo Vazquez-Lombardi, Brendan Roome & Daniel Christ. (2013) Molecular Engineering of Therapeutic Cytokines. Antibodies 2:4, pages 426-451.
Crossref
Crossref
Tamara Veiga-Parga, Amol Suryawanshi, Sachin Mulik, Fernanda Giménez, Shalini Sharma, Tim Sparwasser & Barry T. Rouse. (2012) On the Role of Regulatory T Cells during Viral-Induced Inflammatory Lesions. The Journal of Immunology 189:12, pages 5924-5933.
Crossref
Crossref
Seon‐Yeong Lee, Mi‐La Cho, Hye‐Jwa Oh, Jun‐Geol Ryu, Min‐Jung Park, Joo‐Yeon Jhun, Mi‐Kyung Park, John C. Stone, Ji‐Hyun Ju, Sue‐Yun Hwang, Sung‐Hwan Park, Charles D. Surh & Ho‐Youn Kim. (2012)
Interleukin‐2/anti‐interleukin‐2 monoclonal antibody immune complex suppresses collagen‐induced arthritis in mice by fortifying interleukin‐2/
STAT
5 signalling pathways
. Immunology 137:4, pages 305-316.
Crossref
Crossref
Ethan M. Shevach. (2012) Application of IL-2 therapy to target T regulatory cell function. Trends in Immunology 33:12, pages 626-632.
Crossref
Crossref
Sansana Sawasdikosol, Renyuan Zha, Boyu Yang & Steven Burakoff. (2012) HPK1 as a novel target for cancer immunotherapy. Immunologic Research 54:1-3, pages 262-265.
Crossref
Crossref
Tania Polhill, Geoff Yu Zhang, Min Hu, Andrew Sawyer, Jimmy Jianheng Zhou, Mitsuru Saito, Kylie E. Webster, Ya Wang, Yiping Wang, Shane T. Grey, Jonathan Sprent, David C.H. Harris, Stephen I. Alexander & Yuan Min Wang. (2012) IL-2/IL-2Ab Complexes Induce Regulatory T Cell Expansion and Protect against Proteinuric CKD. Journal of the American Society of Nephrology 23:8, pages 1303-1308.
Crossref
Crossref
Karina García-Martínez & Kalet León. (2012) Modeling the role of IL2 in the interplay between CD4+ helper and regulatory T cells: studying the impact of IL2 modulation therapies. International Immunology 24:7, pages 427-446.
Crossref
Crossref
Onur Boyman, Carsten Krieg, Dirk Homann & Jonathan Sprent. (2012) Homeostatic maintenance of T cells and natural killer cells. Cellular and Molecular Life Sciences 69:10, pages 1597-1608.
Crossref
Crossref
Michael D. RosenblumIris K. GratzJonathan S. PawAbul K. Abbas. (2012) Treating Human Autoimmunity: Current Practice and Future Prospects. Science Translational Medicine 4:125.
Crossref
Crossref
Onur Boyman & Jonathan Sprent. (2012) The role of interleukin-2 during homeostasis and activation of the immune system. Nature Reviews Immunology 12:3, pages 180-190.
Crossref
Crossref
Jessica Ann Chacon, Patrick Hwu & Laszlo G. Radvanyi. 2012. Targeted Therapeutics in Melanoma. Targeted Therapeutics in Melanoma
233
272
.
Alfredo Ulloa-Aguirre, Pascale Crépieux, Anne Poupon, Marie-Christine Maurel & Eric Reiter. (2011) Novel pathways in gonadotropin receptor signaling and biased agonism. Reviews in Endocrine and Metabolic Disorders 12:4, pages 259-274.
Crossref
Crossref
Monika C. Wolkers, Steven J. Bensinger, Douglas R. Green, Stephen P. Schoenberger & Edith M. Janssen. (2011) Interleukin-2 rescues helpless effector CD8+ T cells by diminishing the susceptibility to TRAIL mediated death. Immunology Letters 139:1-2, pages 25-32.
Crossref
Crossref
Chao-Lien Liu, Peiqing Ye, Benjamin C Yen & Carol H Miao. (2011) In Vivo Expansion of Regulatory T cells With IL-2/IL-2 mAb Complexes Prevents Anti-factor VIII Immune Responses in Hemophilia A Mice Treated With Factor VIII Plasmid-mediated Gene Therapy. Molecular Therapy 19:8, pages 1511-1520.
Crossref
Crossref
Joyce Varughese, Emiliano Cocco, Stefania Bellone, Marta Bellone, Paola Todeschini, Luisa Carrara, Peter E. Schwartz, Thomas J. Rutherford, Sergio Pecorelli & Alessandro D. Santin. (2011) High-grade, chemotherapy-resistant primary ovarian carcinoma cell lines overexpress human trophoblast cell-surface marker (Trop-2) and are highly sensitive to immunotherapy with hRS7, a humanized monoclonal anti-Trop-2 antibody. Gynecologic Oncology 122:1, pages 171-177.
Crossref
Crossref
Corey Smith, Michelle Martinez, Jesse Peet & Rajiv Khanna. (2011) Differential Outcome of IL-2/Anti–IL-2 Complex Therapy on Effector and Memory CD8+ T Cells following Vaccination with an Adenoviral Vector Encoding EBV Epitopes. The Journal of Immunology 186:10, pages 5784-5790.
Crossref
Crossref
Jason K. Whitmire. (2011) Induction and function of virus-specific CD4+ T cell responses. Virology 411:2, pages 216-228.
Crossref
Crossref
Mandana Zandian, Kevin R. Mott, Sariah J. Allen, Shuang Chen, Moshe Arditi & Homayon Ghiasi. (2011) IL-2 Suppression of IL-12p70 by a Recombinant HSV-1 Expressing IL-2 Induces T-Cell Auto-Reactivity and CNS Demyelination. PLoS ONE 6:2, pages e16820.
Crossref
Crossref
Kalet León & Karina García-Martínez. 2011. Mathematical Models and Immune Cell Biology. Mathematical Models and Immune Cell Biology
305
337
.
Eva d'Hennezel, Mara Kornete & Ciriaco A Piccirillo. (2010) IL-2 as a therapeutic target for the restoration of Foxp3+ regulatory T cell function in organ-specific autoimmunity: implications in pathophysiology and translation to human disease. Journal of Translational Medicine 8:1.
Crossref
Crossref
Christine E. Richter, Emiliano Cocco, Stefania Bellone, Dan-Arin Silasi, Dominik Rüttinger, Masoud Azodi, Peter E. Schwartz, Thomas J. Rutherford, Sergio Pecorelli & Alessandro D. Santin. (2010) High-grade, chemotherapy-resistant ovarian carcinomas overexpress epithelial cell adhesion molecule (EpCAM) and are highly sensitive to immunotherapy with MT201, a fully human monoclonal anti-EpCAM antibody. American Journal of Obstetrics and Gynecology 203:6, pages 582.e1-582.e7.
Crossref
Crossref
Carsten Krieg, Sven Létourneau, Giuseppe Pantaleo & Onur Boyman. (2010) Improved IL-2 immunotherapy by selective stimulation of IL-2 receptors on lymphocytes and endothelial cells. Proceedings of the National Academy of Sciences 107:26, pages 11906-11911.
Crossref
Crossref
Vanessa Wehbi, Jérémy Decourtye, Vincent Piketty, Guillaume Durand, Eric Reiter & Marie-Christine Maurel. (2010) Selective Modulation of Follicle-Stimulating Hormone Signaling Pathways with Enhancing Equine Chorionic Gonadotropin/Antibody Immune Complexes. Endocrinology 151:6, pages 2788-2799.
Crossref
Crossref
Ruolan Liu, Qinghua Zhou, Antonio La Cava, Denise I. Campagnolo, Luc Van Kaer & Fu‐Dong Shi. (2010)
Expansion of regulatory T cells
via
IL‐2/anti‐IL‐2 mAb complexes suppresses experimental myasthenia
. European Journal of Immunology 40:6, pages 1577-1589.
Crossref
Crossref
Dorothea Busse, Maurus de la Rosa, Kirstin Hobiger, Kevin Thurley, Michael FlossdorfAlexander Scheffold & Thomas Höfer. (2010) Competing feedback loops shape IL-2 signaling between helper and regulatory T lymphocytes in cellular microenvironments. Proceedings of the National Academy of Sciences 107:7, pages 3058-3063.
Crossref
Crossref
Sven LétourneauEster M. M. van LeeuwenCarsten KriegChris MartinGiuseppe PantaleoJonathan Sprent, Charles D. Surh & Onur Boyman. (2010) IL-2/anti-IL-2 antibody complexes show strong biological activity by avoiding interaction with IL-2 receptor α subunit CD25. Proceedings of the National Academy of Sciences 107:5, pages 2171-2176.
Crossref
Crossref
Guillaume Oldenhove, Nicolas Bouladoux, Elizabeth A. Wohlfert, Jason A. Hall, David Chou, Liliane Dos santos, Shaun O'Brien, Rebecca Blank, Erika Lamb, Sundar Natarajan, Robin Kastenmayer, Christopher Hunter, Michael E. Grigg & Yasmine Belkaid. (2009) Decrease of Foxp3+ Treg Cell Number and Acquisition of Effector Cell Phenotype during Lethal Infection. Immunity 31:5, pages 772-786.
Crossref
Crossref
Willem W. Overwijk & Kimberly S. Schluns. (2009) Functions of ?C cytokines in immune homeostasis: Current and potential clinical applications. Clinical Immunology 132:2, pages 153-165.
Crossref
Crossref
Creg J. Workman, Andrea L. Szymczak-Workman, Lauren W. Collison, Meenu R. Pillai & Dario A. A. Vignali. (2009) The development and function of regulatory T cells. Cellular and Molecular Life Sciences 66:16, pages 2603-2622.
Crossref
Crossref
Carsten Krieg & Onur Boyman. (2009) The role of chemokines in cancer immune surveillance by the adaptive immune system. Seminars in Cancer Biology 19:2, pages 76-83.
Crossref
Crossref
Sven L?tourneau, Carsten Krieg, Giuseppe Pantaleo & Onur Boyman. (2009) IL-2? and CD25-dependent immunoregulatory mechanisms in the homeostasis of T-cell subsets. Journal of Allergy and Clinical Immunology 123:4, pages 758-762.
Crossref
Crossref
Tea Gogishvili, Daniela Langenhorst, Fred Lühder, Fernando Elias, Karin Elflein, Kevin M. Dennehy, Ralf Gold & Thomas Hünig. (2009) Rapid Regulatory T-Cell Response Prevents Cytokine Storm in CD28 Superagonist Treated Mice. PLoS ONE 4:2, pages e4643.
Crossref
Crossref
Marek Kovar, Jakub Tomala, Helena Chmelova, Lubomir Kovar, Tomas Mrkvan, Radka Joskova, Zuzana Zakostelska, Tomas Etrych, Jiri Strohalm, Karel Ulbrich, Milada Sirova & Blanka Rihova. (2008) Overcoming Immunoescape Mechanisms of BCL1 Leukemia and Induction of CD8+ T-Cell–Mediated BCL1-Specific Resistance in Mice Cured by Targeted Polymer-Bound Doxorubicin. Cancer Research 68:23, pages 9875-9883.
Crossref
Crossref
Mark S. Wilson, John T. Pesce, Thirumalai R. Ramalingam, Robert W. Thompson, Allen Cheever & Thomas A. Wynn. (2008) Suppression of Murine Allergic Airway Disease by IL-2:Anti-IL-2 Monoclonal Antibody-Induced Regulatory T Cells. The Journal of Immunology 181:10, pages 6942-6954.
Crossref
Crossref
Thomas Hünig. 2007.
111
148
.
Merve Uslu, Esra Albayrak & Fatih Kocabas. (2022) Competitive Inhibition of IL-2/IL-2R Has a Dual Effect on HSC Ex Vivo Expansion and IL-2R (CD25) Content. SSRN Electronic Journal.
Crossref
Crossref