Advanced search
Publication Cover
Expert Opinion on Biological Therapy Volume 6, 2006 - Issue 12
Submit an article Journal homepage
74
Views
27
CrossRef citations to date
0
Altmetric
Drug Evaluation

Alfimeprase: a novel recombinant direct-acting fibrinolytic

Steven R Deitcher Vice President – Chief Medical Scientist, Nuvelo, Inc., 201 Industrial Road, Suite 310, San Carlos, CA 94070, USA. [email protected]
,
Walter D Funk Vice President – Research, Nuvelo, Inc., 201 Industrial Road, Suite 310, San Carlos, CA 94070, USA
,
James Buchanan Senior Director – Drug Safety, Nuvelo, Inc., 201 Industrial Road, Suite 310, San Carlos, CA 94070, USA
,
Shouchun Liu Senior Scientist – Research, Nuvelo, Inc., 201 Industrial Road, Suite 310, San Carlos, CA 94070, USA
,
Michael D Levy Senior Vice President – Research & Development, Nuvelo, Inc., 201 Industrial Road, Suite 310, San Carlos, CA 94070, USA
&
Christopher F Toombs Senior Director – Preclinical Pharmacology, Ikaria, Inc., 1616 Eastlake Ave E, Suite 340, Seattle, WA 98102, USA
Pages 1361-1369 | Published online: 22 Nov 2006

Citations (27)

Keep up to date with the latest research on this topic with citation updates for this article.

Subscribe to citation updates

Read on this site (3)

Adivitiya & Yogender Pal Khasa. (2017) The evolution of recombinant thrombolytics: Current status and future directions. Bioengineered 8:4, pages 331-358.
Read now
Aigang Lu, Yuko Kurosawa, Kenneth Luskey, Gail Pyne-Geithman, Danielle Caudell & Joseph Clark. (2009) Hemorrhagic profile of the fibrinolytic alfimeprase after ischemia and reperfusion. Neurological Research 31:2, pages 209-214.
Read now
Mireille A Moise & Vikram S Kashyap. (2008) Alfimeprase for the treatment of acute peripheral arterial occlusion. Expert Opinion on Biological Therapy 8:5, pages 683-689.
Read now

Articles from other publishers (24)

Amrita Patkar, Rishabh Gadhavi, Neha Kalwadia & R Sekhar. (2021) Our approach and review of current concepts of catheter directed procedures in acute limb ischemia. Indian Journal of Vascular and Endovascular Surgery 8:5, pages 18.
Crossref
Babbal, Adivitiya, Shilpa Mohanty & Yogender Pal Khasa. 2019. High Value Fermentation Products. High Value Fermentation Products 225 263 .
Swaroop S. Kumar & Abdulhameed Sabu. 2019. Therapeutic Enzymes: Function and Clinical Implications. Therapeutic Enzymes: Function and Clinical Implications 345 381 .
Omidreza Tabatabaie, Gyulnara G. Kasumova, Mariam F. Eskander, Jonathan F. Critchlow, Nicholas E. Tawa & Jennifer F. Tseng. (2017) Totally Implantable Venous Access Devices. American Journal of Clinical Oncology 40:1, pages 94-105.
Crossref
Francis S. Markland & Stephen D. Swenson. 2016. Venom Genomics and Proteomics. Venom Genomics and Proteomics 393 424 .
Volodymyr Chernyshenko, Tetyana Platonova, Yevgen Makogonenko, Andriy Rebriev, Lyuba Mikhalovska, Tamara Chernyshenko & Serhiy Komisarenko. (2014) Fibrin(ogen)olytic and platelet modulating activity of a novel protease from the Echis multisquamatis snake venom. Biochimie 105, pages 76-83.
Crossref
Peng Geng, Lan Lin, Yuan Li, Qi Fan, Naihong Wang, Lixin Song & Wenli Li. (2014) A novel fibrin(ogen)olytic trypsin-like protease from Chinese oak silkworm (Antheraea pernyi): Purification and characterization. Biochemical and Biophysical Research Communications 445:1, pages 64-70.
Crossref
Francis S. Markland & Stephen D. Swenson. 2021. Toxinology. Toxinology 1 27 .
Jullia Y. Lee, Francis S. Markland & Benedict R. Lucchesi. (2013) Hirudin and S18886 Maintain Luminal Patency After Thrombolysis With Alfimeprase. Journal of Cardiovascular Pharmacology 61:2, pages 152-159.
Crossref
Francis S. MarklandJr.Jr. & Stephen Swenson. (2013) Snake venom metalloproteinases. Toxicon 62, pages 3-18.
Crossref
Reem Smoum, Abraham Rubinstein, Valery M. Dembitsky & Morris Srebnik. (2012) Boron Containing Compounds as Protease Inhibitors. Chemical Reviews 112:7, pages 4156-4220.
Crossref
Martin Flemmig & Matthias F Melzig. (2012) Serine-proteases as plasminogen activators in terms of fibrinolysis. Journal of Pharmacy and Pharmacology 64:8, pages 1025-1039.
Crossref
Gerald Schielke & Daniel A. Lawrence. 2012. Matrix Proteases in Health and Disease. Matrix Proteases in Health and Disease 127 156 .
Jeffrey I. Weitz, John W. Eikelboom & Meyer Michel Samama. (2012) New Antithrombotic Drugs. Chest 141:2, pages e120S-e151S.
Crossref
Jeffrey I. Weitz. 2012. Braunwald's Heart Disease: A Textbook of Cardiovascular Medicine. Braunwald's Heart Disease: A Textbook of Cardiovascular Medicine 1844 1867 .
Christophe Dommke, Oliver Turschner, Jean-Marie Stassen, Frans Van de Werf, H. Roger Lijnen & Peter Verhamme. (2009) Thrombolytic efficacy of recombinant human microplasmin in a canine model of copper coil-induced coronary artery thrombosis. Journal of Thrombosis and Thrombolysis 30:1, pages 46-54.
Crossref
Johannes A. Eble. (2010) Matrix biology meets toxinology. Matrix Biology 29:4, pages 239-247.
Crossref
Francis S. Markland & Steve Swenson. (2010) Fibrolase: Trials and Tribulations. Toxins 2:4, pages 793-808.
Crossref
Francis S. Markland & Stephen Swenson. 2011. Toxins and Hemostasis. Toxins and Hemostasis 409 427 .
A. M. Perchuc & M. Wilmer. 2010. Hämostaseologie. Hämostaseologie 821 824 .
Peter Verhamme, Martine Jerome, Godelieve Goossens, Joanna Devis, Geert Maleux & Marguerite Stas. (2009) A pilot trial of microplasmin in patients with long-term venous access catheter thrombosis. Journal of Thrombosis and Thrombolysis 28:4, pages 477-481.
Crossref
Steve Pakola, Geraldine Cahillane, Jean-Marie Stassen, H. Roger Lijnen & Peter Verhamme. (2009) Neutralization of α2-antiplasmin by microplasmin: A randomized, double-blind, placebo-controlled, ascending-dose study in healthy male volunteers. Clinical Therapeutics 31:8, pages 1688-1706.
Crossref
Jeffrey I. Weitz, Jack Hirsh & Meyer M. Samama. (2008) New Antithrombotic Drugs. Chest 133:6, pages 234S-256S.
Crossref
Valery Novokhatny. (2008) Structure and activity of plasmin and other direct thrombolytic agents. Thrombosis Research 122, pages S3-S8.
Crossref

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.