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Expert Opinion on Biological Therapy Volume 8, 2008 - Issue 10
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TGF-β3: A promising growth factor in engineered organogenesis

Jinghua Hao Nanyang Technological University, School of Chemical and Biomedical Engineering, Division of Bioengineering, 70 Nanyang Drive, N1.3-B2-13, Singapore 637457, Republic of Singapore +65 6316 8890; +65 67911761; [email protected]; Shandong Provincial Hospital, Department of Gastroenterology and Hepatology, Ji'nan City, Shandong 250021, People's Republic of China
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Rohan R Varshney Nanyang Technological University, School of Chemical and Biomedical Engineering, Division of Bioengineering, 70 Nanyang Drive, N1.3-B2-13, Singapore 637457, Republic of Singapore +65 6316 8890; +65 67911761; [email protected]
&
Dong-An Wang Nanyang Technological University, School of Chemical and Biomedical Engineering, Division of Bioengineering, 70 Nanyang Drive, N1.3-B2-13, Singapore 637457, Republic of Singapore +65 6316 8890; +65 67911761; [email protected]
, PhD
Pages 1485-1493 | Published online: 07 Sep 2008

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Quen Oak Tang, Kaveh Shakib, Manolis Heliotis, Evgenios Tsiridis, Athanasios Mantalaris, Ugo Ripamonti & Eleftherios Tsiridis. (2009) TGF-β3: A potential biological therapy for enhancing chondrogenesis. Expert Opinion on Biological Therapy 9:6, pages 689-701.
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Articles from other publishers (20)

Wei Wang, Liang Chen, Yuxin Zhang, Heng Wang, Dong Dong, Jingjing Zhu, Wei Fu & Tianyi Liu. (2023) Adipose‐derived stem cells enriched with therapeutic mRNA TGF‐β3 and IL‐10 synergistically promote scar‐less wound healing in preclinical models. Bioengineering & Translational Medicine.
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Ying-Ting Zhu, Fu Li, Yuan Zhang, Szu-Yu Chen, Sean Tighe, Shin-Ying Lin & Scheffer C. G. Tseng. (2020) HC-HA/PTX3 Purified From Human Amniotic Membrane Reverts Human Corneal Fibroblasts and Myofibroblasts to Keratocytes by Activating BMP Signaling. Investigative Opthalmology & Visual Science 61:5, pages 62.
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Ana I. Gonçalves, Dominika Berdecka, Márcia T. Rodrigues, Aysegul Dede Eren, Jan Boer, Rui L. Reis & Manuela E. Gomes. (2019) Evaluation of tenogenic differentiation potential of selected subpopulations of human adipose‐derived stem cells. Journal of Tissue Engineering and Regenerative Medicine 13:12, pages 2204-2217.
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Rodrigo A. Somoza, Cristian A. Acevedo, Fernando Albornoz, Patricia Luz-Crawford, Flavio Carrión, Manuel E. Young & Caroline Weinstein-Oppenheimer. (2017) TGF β 3 secretion by three-dimensional cultures of human dental apical papilla mesenchymal stem cells . Journal of Tissue Engineering and Regenerative Medicine 11:4, pages 1045-1056.
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Bo Wei, Yang Guo, Yan Xu, Fengyong Mao, Qingqiang Yao, Chengzhe Jin, Qiangrong Gu & Liming Wang. (2015) Composite scaffolds composed of bone marrow mesenchymal stem cell-derived extracellular matrix and marrow clots promote marrow cell retention and proliferation. Journal of Biomedical Materials Research Part A 103:7, pages 2374-2382.
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Kuei-Chang Li & Yu-Chen Hu. (2015) Cartilage Tissue Engineering: Recent Advances and Perspectives from Gene Regulation/Therapy. Advanced Healthcare Materials 4:7, pages 948-968.
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Henning MadryAna Rey-RicoJagadeesh K. VenkatesanBrian JohnstoneMagali Cucchiarini. (2014) Transforming Growth Factor Beta-Releasing Scaffolds for Cartilage Tissue Engineering. Tissue Engineering Part B: Reviews 20:2, pages 106-125.
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Mingrui TangYuxin WangSiyuan HanShu GuoDi Wang. (2013) Transforming Growth Factor-Beta3 Gene Polymorphisms and Nonsyndromic Cleft Lip and Palate Risk: A Meta-Analysis. Genetic Testing and Molecular Biomarkers 17:12, pages 881-889.
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Bradford E. Hall, Umesh D. Wankhade, Joanne E. Konkel, Karthik Cherukuri, Chandrasekharam N. Nagineni, Kathleen C. Flanders, Praveen R. Arany, Wanjun Chen, Sushil G. Rane & Ashok B. Kulkarni. (2013) Transforming Growth Factor-β3 (TGF-β3) Knock-in Ameliorates Inflammation Due to TGF-β1 Deficiency While Promoting Glucose Tolerance. Journal of Biological Chemistry 288:44, pages 32074-32092.
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Matthew J. Finley, Katherine A. Clark, Ivan S. Alferiev, Robert J. Levy & Stanley J. Stachelek. (2013) Intracellular signaling mechanisms associated with CD47 modified surfaces. Biomaterials 34:34, pages 8640-8649.
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Cristian A. Acevedo, Rodrigo A. Somoza, Caroline Weinstein-Oppenheimer, Samy Silva, Macarena Moreno, Elizabeth Sánchez, Fernando Albornoz, Manuel E. Young, William MacNaughtan & Javier Enrione. (2012) Improvement of human skin cell growth by radiation-induced modifications of a Ge/Ch/Ha scaffold. Bioprocess and Biosystems Engineering 36:3, pages 317-324.
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Meenu Wadhwa, Paula Dilger, Michelle Hamill, David Bending, Sarah Gibbs, Guoping Wu, Jo Read, Tony Wyss-Coray, Hui Zhang, John Little, Katherine M. Getliffe, Gao Kai, Weihong Wang, David Bender, Chris Bird, Alan B. Heath, Anne Cooke & Robin Thorpe. (2012) The 1st International standard for transforming growth factor-β3 (TGF-β3). Journal of Immunological Methods 380:1-2, pages 1-9.
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Feng Zhang, Yongchang Yao, Kai Su, Patricia Xiaotian Pang, Ruijie Zhou, Yingjun Wang & Dong-An Wang. (2011) Redifferentiation of Dedifferentiated Chondrocytes by Adenoviral Vector-Mediated TGF-β3 and Collagen-1 Silencing shRNA in 3D Culture. Annals of Biomedical Engineering 39:12, pages 3042-3054.
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D. Karamichos, A. E. K. Hutcheon & J. D. Zieske. (2011) Transforming growth factor-β3 regulates assembly of a non-fibrotic matrix in a 3D corneal model. Journal of Tissue Engineering and Regenerative Medicine 5:8, pages e228-e238.
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Yongchang Yao, Feng Zhang, Ruijie Zhou, Meng Li & Dong-An Wang. (2010) Continuous supply of TGFβ3 via adenoviral vector promotes type I collagen and viability of fibroblasts in alginate hydrogel. Journal of Tissue Engineering and Regenerative Medicine 4:7, pages 497-504.
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Matthias Zscharnack, Pierre Hepp, Robert Richter, Thomas Aigner, Ronny Schulz, Jeremy Somerson, Christoph Josten, Augustinus Bader & Bastian Marquass. (2010) Repair of Chronic Osteochondral Defects Using Predifferentiated Mesenchymal Stem Cells in an Ovine Model. The American Journal of Sports Medicine 38:9, pages 1857-1869.
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Rohan R. Varshney, Ruijie Zhou, Jinghua Hao, Suan Siong Yeo, Wai Hon Chooi, Jiabing Fan & Dong-An Wang. (2010) Chondrogenesis of synovium-derived mesenchymal stem cells in gene-transferred co-culture system. Biomaterials 31:26, pages 6876-6891.
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Yongchang Yao, Feng Zhang, Ruijie Zhou, Kai Su, Jiabing Fan & Dong-An Wang. (2010) Effects of combinational adenoviral vector-mediated TGFβ3 transgene and shRNA silencing type I collagen on articular chondrogenesis of synovium-derived mesenchymal stem cells. Biotechnology and Bioengineering 106:5, pages 818-828.
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Hae-Yong Lee, Ryun-Hwa Kang, Sang-In Chung, Soo-Hyun Cho & Yoo-Sik Yoon. (2010) Effects of Baicalin on Gene Expression Profiles during Adipogenesis of 3T3-L1 Cells. Journal of the Korean Society of Food Science and Nutrition 39:1, pages 54-63.
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Jan O Gordeladze, Farida Djouad, Jean-Marc Brondello, Daniele Noël, Isabelle Duroux-Richard, Florence Apparailly & Christian Jorgensen. (2009) Concerted stimuli regulating osteo-chondral differentiation from stem cells: phenotype acquisition regulated by microRNAs. Acta Pharmacologica Sinica 30:10, pages 1369-1384.
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