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Drug Evaluations

Belimumab, an anti-BLyS human monoclonal antibody for potential treatment of inflammatory autoimmune diseases

Pages 1805-1814 | Published online: 10 Oct 2008

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Hakan Parlakpinar & Mehmet Gunata. (2021) Transplantation and immunosuppression: a review of novel transplant-related immunosuppressant drugs. Immunopharmacology and Immunotoxicology 43:6, pages 651-665.
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Daniel R. Getts, Meghann T. Getts, Derrick P. McCarthy, Emily ML Chastain & Stephen D. Miller. (2010) Have we overestimated the benefit of human(ized) antibodies?. mAbs 2:6, pages 682-694.
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Ronald F Parsons, Kumar Vivek, Robert R Redfield, Thi-Sau Migone, Michael P Cancro, Ali Naji & Hooman Noorchashm. (2009) B-cell tolerance in transplantation: is repertoire remodeling the answer?. Expert Review of Clinical Immunology 5:6, pages 703-723.
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C Bracewell, JD Isaacs, P Emery & WF Ng. (2009) Atacicept, a novel B cell-targeting biological therapy for the treatment of rheumatoid arthritis. Expert Opinion on Biological Therapy 9:7, pages 909-919.
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Hamideh Raeisi, Masoumeh Azimirad, Ali Nabavi-Rad, Hamid Asadzadeh Aghdaei, Abbas Yadegar & Mohammad Reza Zali. (2022) Application of recombinant antibodies for treatment of Clostridioides difficile infection: Current status and future perspective. Frontiers in Immunology 13.
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Srikanth Mukkera, Maneesh Mannem, Karthik Chamarti, Leela Pillarisetty, Sai Swarupa Vulasala, Lakshmi Alahari, Anusha Ammu, Akshathh Mukkera & Rajeev K Vadlapatla. (2022) Systemic Lupus Erythematosus-Associated Serositis Managed With Intravenous Belimumab: A Case Report. Cureus.
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Marvin J. Fritzler & Michael Mahler. 2021. Precision Medicine and Artificial Intelligence. Precision Medicine and Artificial Intelligence 39 63 .
Ruei-Min Lu, Yu-Chyi Hwang, I-Ju Liu, Chi-Chiu Lee, Han-Zen Tsai, Hsin-Jung Li & Han-Chung Wu. (2020) Development of therapeutic antibodies for the treatment of diseases. Journal of Biomedical Science 27:1.
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Sandra A. Morais, Andreia Vilas-Boas & David A. Isenberg. (2015) B-cell survival factors in autoimmune rheumatic disorders. Therapeutic Advances in Musculoskeletal Disease 7:4, pages 122-151.
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Ignasi Rodriguez-Pintó, Gerard Espinosa & Ricard Cervera. (2015) Updating the clinical evidence on belimumab role modulating B-cell response and treatment of systemic lupus erythematosus. Clinical Investigation 5:6, pages 561-571.
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Fabienne Niederer, Almut Scherer, Diego Kyburz, Renate E. Gay, Steffen Gay, Beat A. Michel & Adrian Ciurea. (2013) Taux sériques de BAFF chez les patients atteints de spondylarthrite ankylosante et traités par anti-TNF. Revue du Rhumatisme 80:4, pages 417-419.
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Yehunda Shoenfeld, Pier Luigi Meroni & Ricard CerveraRicard CerveraGerard Espinosa. 2012. Immunotherapeutic Agents for SLE. Immunotherapeutic Agents for SLE 42 54 .
Ricard Cervera & Gerard Espinosa. (2011) Clinical evidence of the role of belimumab in the treatment of systemic lupus erythematosus. Clinical Investigation 1:11, pages 1555-1561.
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Changhai Ding, Ran Li, Jianhua Xu, Flavia Cicuttini & Graeme Jones. (2011) Belimumab therapy for systemic lupus erythematosus and potential treatment of rheumatoid arthritis. Drug Development Research 72:7, pages 623-633.
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Yunjie Liu, Lingling Zhang, Yingqi Wu, Tong Tong, Wendi Zhao, Peipei Li, Min Huang, Wenxiang Wang, Jianmin Fang & Wei Wei. (2011) Therapeutic effects of TACI-Ig on collagen-induced arthritis by regulating T and B lymphocytes function in DBA/1 mice. European Journal of Pharmacology 654:3, pages 304-314.
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Norman T. Ilowite & Ronald M. Laxer. 2011. Textbook of Pediatric Rheumatology. Textbook of Pediatric Rheumatology 71 126 .
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Ronald F. Parsons, Kumar Vivek, Robert R. RedfieldIIIIII, Thi-Sau Migone, Michael P. Cancro, Ali Naji & Hooman Noorchashm. (2010) B-lymphocyte homeostasis and BLyS-directed immunotherapy in transplantation. Transplantation Reviews 24:4, pages 207-221.
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H. L. Wright, R. J. Moots, R. C. Bucknall & S. W. Edwards. (2010) Neutrophil function in inflammation and inflammatory diseases. Rheumatology 49:9, pages 1618-1631.
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Patrizia Scapini, Yongmei Hu, Ching-Liang Chu, Thi-Sau Migone, Anthony L. DeFranco, Marco A. Cassatella & Clifford A. Lowell. (2010) Myeloid cells, BAFF, and IFN-γ establish an inflammatory loop that exacerbates autoimmunity in Lyn-deficient mice. Journal of Experimental Medicine 207:8, pages 1757-1773.
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Susan Lee & Mark Ballow. (2010) Monoclonal antibodies and fusion proteins and their complications: Targeting B cells in autoimmune diseases. Journal of Allergy and Clinical Immunology 125:4, pages 814-820.
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M. Fabris, F. Grimaldi, D. Villalta, A. Picierno, C. Fabro, M. Bolzan, S. De Vita & E. Tonutti. (2010) BLyS and April serum levels in patients with autoimmune thyroid diseases. Autoimmunity Reviews 9:3, pages 165-169.
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Diana J. Auyeung-Kim, Madhav N. Devalaraja, Thi-Sau Migone, Wendy Cai & Gary J. Chellman. (2009) Developmental and peri-postnatal study in cynomolgus monkeys with belimumab, a monoclonal antibody directed against B-lymphocyte stimulator. Reproductive Toxicology 28:4, pages 443-455.
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