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Malaria vaccines: the case for a whole-organism approach

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Pages 441-448 | Published online: 19 Mar 2008

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Susanne H Sheehy, Alexander D Douglas & Simon J Draper. (2013) Challenges of assessing the clinical efficacy of asexual blood-stage malaria vaccines. Human Vaccines & Immunotherapeutics 9:9, pages 1831-1840.
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A. L. Goodman & S. J. Draper. (2010) Blood-stage malaria vaccines — recent progress and future challenges. Annals of Tropical Medicine & Parasitology 104:3, pages 189-211.
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Jürgen F Kun & Elisandra Grangeiro de Carvalho. (2009) Novel therapeutic targets in Plasmodium falciparum: aquaglyceroporins. Expert Opinion on Therapeutic Targets 13:4, pages 385-394.
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Articles from other publishers (17)

Sara E. White, Steven A. Harvey, Graciela Meza, Alejandro Llanos, Mitchel Guzman, Dionicia Gamboa & Joseph M. Vinetz. (2018) Acceptability of a herd immunity-focused, transmission-blocking malaria vaccine in malaria-endemic communities in the Peruvian Amazon: an exploratory study. Malaria Journal 17:1.
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Ahmad Syibli Othman, Blandine M. Franke-Fayard, Takashi Imai, Esmé T. I. van der Gracht, Anke Redeker, Ahmed M. Salman, Catherin Marin-Mogollon, Jai Ramesar, Séverine Chevalley-Maurel, Chris J. Janse, Ramon Arens & Shahid M. Khan. (2018) OX40 Stimulation Enhances Protective Immune Responses Induced After Vaccination With Attenuated Malaria Parasites. Frontiers in Cellular and Infection Microbiology 8.
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Simone Haeberlein, Séverine Chevalley-Maurel, Arifa Ozir-Fazalalikhan, Hester Koppejan, Beatrice M. F. Winkel, Jai Ramesar, Shahid M. Khan, Robert W. Sauerwein, Meta Roestenberg, Chris J. Janse, Hermelijn H. Smits & Blandine Franke-Fayard. (2017) Protective immunity differs between routes of administration of attenuated malaria parasites independent of parasite liver load. Scientific Reports 7:1.
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Dabbu Kumar Jaijyan, Himanshu Singh & Agam Prasad Singh. (2015) A Sporozoite- and Liver Stage-expressed Tryptophan-rich Protein Plays an Auxiliary Role in Plasmodium Liver Stage Development and Is a Potential Vaccine Candidate. Journal of Biological Chemistry 290:32, pages 19496-19511.
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Alberto Pinzon-Charry, Tonia Woodberry, Vivian Kienzle, Virginia McPhun, Gabriela Minigo, Daniel A. Lampah, Enny Kenangalem, Christian Engwerda, J. Alejandro López, Nicholas M. Anstey & Michael F. Good. (2013) Apoptosis and dysfunction of blood dendritic cells in patients with falciparum and vivax malaria. Journal of Experimental Medicine 210:8, pages 1635-1646.
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Megumi Inoue, Jianxia Tang, Mana Miyakoda, Osamu Kaneko, Katsuyuki Yui & Richard Culleton. (2012) The species specificity of immunity generated by live whole organism immunisation with erythrocytic and pre-erythrocytic stages of rodent malaria parasites and implications for vaccine development. International Journal for Parasitology 42:9, pages 859-870.
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Takeshi Annoura, Ivo H.J. Ploemen, Ben C.L. van Schaijk, Mohammed Sajid, Martijn W. Vos, Geert-Jan van Gemert, Severine Chevalley-Maurel, Blandine M.D. Franke-Fayard, Cornelus C. Hermsen, Audrey Gego, Jean-Francois Franetich, Dominique Mazier, Stephen L. Hoffman, Chris J. Janse, Robert W. Sauerwein & Shahid M. Khan. (2012) Assessing the adequacy of attenuation of genetically modified malaria parasite vaccine candidates. Vaccine 30:16, pages 2662-2670.
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Noel J. Gerald, Victoria Majam, Babita Mahajan, Yukiko Kozakai & Sanjai Kumar. (2011) Protection from Experimental Cerebral Malaria with a Single Dose of Radiation-Attenuated, Blood-Stage Plasmodium berghei Parasites. PLoS ONE 6:9, pages e24398.
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Rick L. Tarleton & Edward J. Pearce. 2010. The Immune Response to Infection. The Immune Response to Infection 143 153 .
Martha Sedegah, William O. Rogers, Maria Belmonte, Arnel Belmonte, Glenna Banania, Noelle B. Patterson, Denis Rusalov, Marilyn Ferrari, Thomas L. Richie & Denise L. Doolan. (2010) Vaxfectin? enhances both antibody and in vitro T cell responses to each component of a 5-gene Plasmodium falciparum plasmid DNA vaccine mixture administered at low doses. Vaccine 28:17, pages 3055-3065.
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Andrea Cavalli, Federica Lizzi, Salvatore Bongarzone, Federica Belluti, Lorna Piazzi & Maria Laura Bolognesi. (2010) Complementary medicinal chemistry-driven strategies toward new antitrypanosomal and antileishmanial lead drug candidates. FEMS Immunology & Medical Microbiology 58:1, pages 51-60.
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Anthony A. Holder. (2009) Malaria Vaccines: Where Next?. PLoS Pathogens 5:10, pages e1000638.
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Jack S Richards & James G Beeson. (2009) The future for blood‐stage vaccines against malaria. Immunology & Cell Biology 87:5, pages 377-390.
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Irwin W. Sherman. 2009. The Elusive Malaria Vaccine. The Elusive Malaria Vaccine 327 373 .
Michael F. Good. (2009) The hope but challenge for developing a vaccine that might control malaria. European Journal of Immunology 39:4, pages 939-943.
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Magdalena Plebanski, Emily Locke, James W. Kazura & Ross L. Coppel. (2008) Malaria vaccines: into a mirror, darkly?. Trends in Parasitology 24:12, pages 532-536.
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Ben C. L. van Schaijk, Chris J. Janse, Geert-Jan van Gemert, Melissa R. van Dijk, Audrey Gego, Jean-Francois Franetich, Marga van de Vegte-Bolmer, Samir Yalaoui, Olivier Silvie, Stephen L. Hoffman, Andrew P. Waters, Dominique Mazier, Robert W. Sauerwein & Shahid M. Khan. (2008) Gene Disruption of Plasmodium falciparum p52 Results in Attenuation of Malaria Liver Stage Development in Cultured Primary Human Hepatocytes. PLoS ONE 3:10, pages e3549.
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