Citations (36)
Keep up to date with the latest research on this topic with citation updates for this article.
Read on this site (5)
Massimiliano Sarra, Eleonora Franzè, Francesco Pallone & Giovanni Monteleone. (2011) Targeting interleukin-21 in inflammatory diseases. Expert Opinion on Therapeutic Targets 15:6, pages 695-702.
Read now
Read now
Francesco Pallone, Daniele Fina, Roberta Caruso & Giovanni Monteleone. (2010) Role of IL-21 in inflammatory bowel disease. Expert Review of Clinical Immunology 6:4, pages 537-541.
Read now
Read now
Mehmood H Hashmi & Peter J Van Veldhuizen. (2010) Interleukin-21: updated review of Phase I and II clinical trials in metastatic renal cell carcinoma, metastatic melanoma and relapsed/refractory indolent non-Hodgkin's lymphoma. Expert Opinion on Biological Therapy 10:5, pages 807-817.
Read now
Read now
Christian M Capitini, Crystal L Mackall & Alan S Wayne. (2010) Immune-based therapeutics for pediatric cancer. Expert Opinion on Biological Therapy 10:2, pages 163-178.
Read now
Read now
Javier Briones. (2009) Emerging therapies for B-cell non-Hodgkin lymphoma. Expert Review of Anticancer Therapy 9:9, pages 1305-1316.
Read now
Read now
Articles from other publishers (31)
Ting Wang, Zhenfa Chen, Cui Li, Wei Zhang, Wenbin Huang, Jun Xue, Jundong Wang & Shufeng Li. (2023)
PAX5
and circ1857 affected
DLBCL
progression and B‐cell proliferation through regulating
GINS1
. Cancer Science 114:8, pages 3203-3215.
Crossref
Crossref
Aleksandra Mielczarek-Palacz, Celina Kruszniewska-Rajs, Marta Smycz-Kubańska, Jarosław Strzelczyk, Wojciech Szanecki, Andrzej Witek & Joanna Magdalena Gola. (2021) The Assessment of IL-21 and IL-22 at the mRNA Level in Tumor Tissue and Protein Concentration in Serum and Peritoneal Fluid in Patients with Ovarian Cancer. Journal of Clinical Medicine 10:14, pages 3058.
Crossref
Crossref
Zheng-Wei Cui, Xiang-Yang Zhang, Xiao-Hua Chen, Xu-Jie Zhang & Yong-An Zhang. (2020) Splicing variants of grass carp (Ctenopharyngodon idellus) IL-21: Functions in IgM+ B cell proliferation and IgM secretion. Developmental & Comparative Immunology 110, pages 103728.
Crossref
Crossref
Xiaowei Chi, Peiwei Yang, Erhao Zhang, Jieyi Gu, Hui Xu, Mengwei Li, Xinmei Gao, Xin Li, Yinan Zhang, Hanmei Xu & Jialiang Hu. (2019) Significantly increased anti‐tumor activity of carcinoembryonic antigen‐specific chimeric antigen receptor T cells in combination with recombinant human IL‐12. Cancer Medicine 8:10, pages 4753-4765.
Crossref
Crossref
Liannv Qiu, Qinhua Yu, Yonglie Zhou, Sujie Zheng, Jiaojiao Tao, Qian Jiang & Guorong Yuan. (2018)
Functionally impaired follicular helper T cells induce regulatory B cells and
CD
14
+
human leukocyte antigen‐
DR
−
cell differentiation in non‐small cell lung cancer
. Cancer Science 109:12, pages 3751-3761.
Crossref
Crossref
Liannv Qiu, Yonglie Zhou, Qinhua Yu, Sujie Zheng, Zhenni Wang & Qiang Huang. (2018) RETRACTED: Elevated levels of follicular T helper cells and their association with therapeutic effects in patients with chronic lymphocytic leukaemia. Immunology Letters 197, pages 15-28.
Crossref
Crossref
Stephen M. Ansell. (2017) Anti-CD20-IL-21 fusokine: the tail wags the dog. Blood 129:16, pages 2209-2210.
Crossref
Crossref
Russell Pachynski & Holbrook Kohrt. 2016. Novel Immunotherapeutic Approaches to the Treatment of Cancer. Novel Immunotherapeutic Approaches to the Treatment of Cancer
79
108
.
Tao WangAlexis CunninghamAyotunde O. DokunSurovi HazarikaKevin HoustonLingdan ChenR. John LyeRosanne SpolskiWarren J. LeonardBrian H. Annex. (2015) Loss of Interleukin-21 Receptor Activation in Hypoxic Endothelial Cells Impairs Perfusion Recovery After Hindlimb Ischemia. Arteriosclerosis, Thrombosis, and Vascular Biology 35:5, pages 1218-1225.
Crossref
Crossref
Chansavath Phetsouphanh, Yin Xu & John Zaunders. (2015) CD4 T Cells Mediate Both Positive and Negative Regulation of the Immune Response to HIV Infection: Complex Role of T Follicular Helper Cells and Regulatory T Cells in Pathogenesis. Frontiers in Immunology 5.
Crossref
Crossref
Suhendan Ekmekcioglu, Razelle Kurzrock & Elizabeth A. Grimm. 2015. The Molecular Basis of Cancer. The Molecular Basis of Cancer
789
808.e4
.
. 2015. Interleukins in Cancer Biology. Interleukins in Cancer Biology
327
329
.
Hui WangMingjun WangZhenjun FengLei ChenLei GaoQiang LiLi ZhangJunjie Ma. (2014) Functional Interleukin-21 Polymorphism Is a Protective Factor of Diffuse Large B-Cell Lymphoma. DNA and Cell Biology 33:11, pages 775-780.
Crossref
Crossref
Magdalena Hagn, Sue E. Blackwell, Thamara Beyer, Verena Ebel, Dorit Fabricius, Stefanie Lindner, Stefan Stilgenbauer, Thomas Simmet, Constantine Tam, Paul Neeson, Joseph A. Trapani, Hubert Schrezenmeier, George J. Weiner & Bernd Jahrsdörfer. (2014) B-CLL cells acquire APC- and CTL-like phenotypic characteristics after stimulation with CpG ODN and IL-21. International Immunology 26:7, pages 383-395.
Crossref
Crossref
Valentina Rigo, Maria Valeria Corrias, Anna Maria Orengo, Antonella Brizzolara, Laura Emionite, Daniela Fenoglio, Gilberto Filaci, Michela Croce & Silvano Ferrini. (2014) Recombinant IL-21 and anti-CD4 antibodies cooperate in syngeneic neuroblastoma immunotherapy and mediate long-lasting immunity. Cancer Immunology, Immunotherapy 63:5, pages 501-511.
Crossref
Crossref
Liang Wu, Barbro Ehlin‐Henriksson, Hong Zhu, Ingemar Ernberg & George Klein. (2013) EBV counteracts IL‐21‐induced apoptosis in an EBV‐positive diffuse large B‐cell lymphoma cell line. International Journal of Cancer 133:3, pages 766-770.
Crossref
Crossref
John M. Timmerman, John C. Byrd, David J. Andorsky, Reiko E. Yamada, Janet Kramer, Natarajan Muthusamy, Naomi Hunder & John M. Pagel. (2012) A Phase I Dose-Finding Trial of Recombinant Interleukin-21 and Rituximab in Relapsed and Refractory Low Grade B-cell Lymphoproliferative Disorders. Clinical Cancer Research 18:20, pages 5752-5760.
Crossref
Crossref
Jan Emmerich, John B. Mumm, Ivan H. Chan, Drake LaFace, Hoa Truong, Terrill McClanahan, Daniel M. Gorman & Martin Oft. (2012)
IL-10 Directly Activates and Expands Tumor-Resident CD8+ T Cells without
De Novo
Infiltration from Secondary Lymphoid Organs
. Cancer Research 72:14, pages 3570-3581.
Crossref
Crossref
Magdalena Hagn, Kai Sontheimer, Karen Dahlke, Sabine Brueggemann, Christof Kaltenmeier, Thamara Beyer, Stefanie Hofmann, Oleg Lunov, Thomas FE Barth, Dorit Fabricius, Kyrylo Tron, Gerd Ulrich Nienhaus, Thomas Simmet, Hubert Schrezenmeier & Bernd Jahrsdörfer. (2011) Human B cells differentiate into granzyme B‐secreting cytotoxic B lymphocytes upon incomplete T‐cell help. Immunology & Cell Biology 90:4, pages 457-467.
Crossref
Crossref
Claire Galand, Sabrina Donnou, Lucile Crozet, S?verine Brunet, Val?rie Touitou, Hanane Ouakrim, Wolf Herman Fridman, Catherine Saut?s-Fridman & Sylvain Fisson. (2011) Th17 Cells Are Involved in the Local Control of Tumor Progression in Primary Intraocular Lymphoma. PLoS ONE 6:9, pages e24622.
Crossref
Crossref
Courtney Nicholas & Gregory B Lesinski. (2011) Immunomodulatory cytokines as therapeutic agents for melanoma. Immunotherapy 3:5, pages 673-690.
Crossref
Crossref
Feng-Lai Yuan, Wei Hu, Wei-Guo Lu, Xia Li, Jian-Ping Li, Rui-Sheng Xu, Cheng-Wan Li, Fei-Hu Chen & Cheng Jin. (2010) Targeting interleukin-21 in rheumatoid arthritis. Molecular Biology Reports 38:3, pages 1717-1721.
Crossref
Crossref
Roch Houot, Holbrook Kohrt, Matthew J. Goldstein & Ronald Levy. (2011) Immunomodulating antibodies and drugs for the treatment of hematological malignancies. Cancer and Metastasis Reviews 30:1, pages 97-109.
Crossref
Crossref
Tiehui Wang, Patricia Diaz-Rosales, Maria M. Costa, Scott Campbell, Michael Snow, Bertrand Collet, Samuel A. M. Martin & Christopher J. Secombes. (2011)
Functional Characterization of a Nonmammalian IL-21: Rainbow Trout
Oncorhynchus mykiss
IL-21 Upregulates the Expression of the Th Cell Signature Cytokines IFN-γ, IL-10, and IL-22
. The Journal of Immunology 186:2, pages 708-721.
Crossref
Crossref
Raffaella Meazza, Bruno Azzarone, Anna Maria Orengo & Silvano Ferrini. (2011) Role of Common-Gamma Chain Cytokines in NK Cell Development and Function: Perspectives for Immunotherapy. Journal of Biomedicine and Biotechnology 2011, pages 1-16.
Crossref
Crossref
Björn Engelbrekt Wahlin, Mohit Aggarwal, Santiago Montes-Moreno, Luis Francisco Gonzalez, Giovanna Roncador, Lidia Sanchez-Verde, Birger Christensson, Birgitta Sander & Eva Kimby. (2010) A Unifying Microenvironment Model in Follicular Lymphoma: Outcome Is Predicted by Programmed Death-1–Positive, Regulatory, Cytotoxic, and Helper T Cells and Macrophages. Clinical Cancer Research 16:2, pages 637-650.
Crossref
Crossref
Alexandre Iannello, Mohamed-Rachid Boulassel, Suzanne Samarani, Olfa Debbeche, Cécile Tremblay, Emil Toma, Jean-Pierre Routy & Ali Ahmad. (2010) Dynamics and Consequences of IL-21 Production in HIV-Infected Individuals: A Longitudinal and Cross-Sectional Study. The Journal of Immunology 184:1, pages 114-126.
Crossref
Crossref
Massimiliano Sarra & Giovanni Monteleone. (2010) Interleukin-21: A New Mediator of Inflammation in Systemic Lupus Erythematosus. Journal of Biomedicine and Biotechnology 2010, pages 1-6.
Crossref
Crossref
Gianpietro DottiBarbara SavoldoMalcolm Brenner. (2009) Fifteen Years of Gene Therapy Based on Chimeric Antigen Receptors: “Are We Nearly There Yet?”. Human Gene Therapy 20:11, pages 1229-1239.
Crossref
Crossref
Yrina Rochman, Rosanne Spolski & Warren J. Leonard. (2009) New insights into the regulation of T cells by γc family cytokines. Nature Reviews Immunology 9:7, pages 480-490.
Crossref
Crossref
Alexandre Iannello & Ali Ahmad. (2009) L’interleukine-21, un nouvel adjuvant contre le cancer ?. médecine/sciences 25:4, pages 341-343.
Crossref
Crossref