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Emerging drug therapies in Huntington's disease

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Pages 273-297 | Published online: 20 May 2009

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Laetitia C Schwab, Shaady N Garas, Janelle Drouin-Ouellet, Sarah L Mason, Simon R Stott & Roger A Barker. (2015) Dopamine and Huntington’s disease. Expert Review of Neurotherapeutics 15:4, pages 445-458.
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Muath Suliman, Sulieman Ibraheem Shelash Al-Hawary, F. Al-dolaimy, Ahmed Hjazi, Sami G. Almalk, Adnan Taan Alkhafaji, Ahmed Hussien Alawadi, Ali Alsaalamy, Sheela Bijlwan & Yasser Fakri Mustafa. (2023) Inflammatory diseases: function of LncRNAs in their emergence and the role of mesenchymal stem cell secretome in their treatment. Pathology - Research and Practice, pages 154758.
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Bimala Malla, Xuanzong Guo, Gökçe Senger, Zoi Chasapopoulou & Ferah Yildirim. (2021) A Systematic Review of Transcriptional Dysregulation in Huntington’s Disease Studied by RNA Sequencing. Frontiers in Genetics 12.
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Horia Paunescu, Lorena Dima, Isabel Ghita, Laurenţiu Coman, Petru Iulian Ifteni, Ion Fulga & Oana Andreia Coman. (2020) A Systematic Review of Clinical Studies on the Effect of Psychoactive Cannabinoids in Psychiatric Conditions in Alzheimer Dementia. American Journal of Therapeutics 27:3, pages e249-e269.
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Sunpreet Kaur, Shamsher Singh, Anchal Arora, Parladh Ram, Sachin Kumar, Puneet Kumar & Sara Nidal Abed. 2020. Frontiers in Pharmacology of Neurotransmitters. Frontiers in Pharmacology of Neurotransmitters 241 292 .
Edina Silajdžić & Maria Björkqvist. (2018) A Critical Evaluation of Wet Biomarkers for Huntington’s Disease: Current Status and Ways Forward. Journal of Huntington's Disease 7:2, pages 109-135.
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Maurice Garret, Zhuowei Du, Marine Chazalon, Yoon H. Cho & Jérôme Baufreton. (2018) Alteration of GABA ergic neurotransmission in Huntington's disease . CNS Neuroscience & Therapeutics 24:4, pages 292-300.
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Rhia Ghosh & Sarah J. Tabrizi. 2018. Neurogenetics, Part I. Neurogenetics, Part I 255 278 .
Claudia Rangel-Barajas & George V. Rebec. (2016) Dysregulation of Corticostriatal Connectivity in Huntington’s Disease: A Role for Dopamine Modulation. Journal of Huntington's Disease 5:4, pages 303-331.
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M.L. Choi, F. Begeti, J.H. Oh, S.Y. Lee, G.C. O'Keeffe, C.D. Clelland, P. Tyers, Z.H. Cho, Y.B. Kim & R.A. Barker. (2014) Dopaminergic manipulations and its effects on neurogenesis and motor function in a transgenic mouse model of Huntington's disease. Neurobiology of Disease 66, pages 19-27.
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Robert Wyse, Gary Dunbar & Julien Rossignol. (2014) Use of Genetically Modified Mesenchymal Stem Cells to Treat Neurodegenerative Diseases. International Journal of Molecular Sciences 15:2, pages 1719-1745.
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Roger A. Barker & Sarah L. Mason. (2013) Mapping the natural history of Huntington disease. Nature Reviews Neurology 10:1, pages 12-13.
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. 2013. Metal-based Neurodegeneration. Metal-based Neurodegeneration 337 394 .
Shermali Gunawardena. (2013) Nanoparticles in the Brain: A Potential Therapeutic System Targeted to an Early Defect Observed in Many Neurodegenerative Diseases. Pharmaceutical Research 30:10, pages 2459-2474.
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A. Jahanshahi, R. Vlamings, W.M.C. van Roon-Mom, R.L.M. Faull, H.J. Waldvogel, M.L.F. Janssen, Y. Yakkioui, D.H. Zeef, E. Kocabicak, H.W.M. Steinbusch & Y. Temel. (2013) Changes in brainstem serotonergic and dopaminergic cell populations in experimental and clinical Huntington’s disease. Neuroscience 238, pages 71-81.
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R MacLeod, A Tibben, M Frontali, G Evers‐Kiebooms, A Jones, A Martinez‐Descales & RA Roos. (2013) Recommendations for the predictive genetic test in Huntington's disease. Clinical Genetics 83:3, pages 221-231.
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Rhia Ghosh & Sarah J. Tabrizi. 2015. Behavioral Neurobiology of Huntington's Disease and Parkinson's Disease. Behavioral Neurobiology of Huntington's Disease and Parkinson's Disease 3 31 .
Rinske Vlamings, Dagmar H. Zeef, Marcus L. F. Janssen, Mayke Oosterloo, Frederic Schaper, Ali Jahanshahi & Yasin Temel. (2012) Lessons Learned from the Transgenic Huntington's Disease Rats. Neural Plasticity 2012, pages 1-8.
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Puneet Kumar, Harikesh Kalonia & Anil Kumar. (2010) Novel protective mechanisms of antidepressants against 3-nitropropionic acid induced Huntington’s-like symptoms: a comparative study. Journal of Psychopharmacology 25:10, pages 1399-1411.
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Jess Nithianantharajah & Anthony J. Hannan. (2011) Mechanisms mediating brain and cognitive reserve: Experience-dependent neuroprotection and functional compensation in animal models of neurodegenerative diseases. Progress in Neuro-Psychopharmacology and Biological Psychiatry 35:2, pages 331-339.
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Christopher A Ross & Sarah J Tabrizi. (2011) Huntington's disease: from molecular pathogenesis to clinical treatment. The Lancet Neurology 10:1, pages 83-98.
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Marianne J.U. Novak & Sarah J. Tabrizi. 2011. Pathophysiology, Pharmacology, and Biochemistry of Dyskinesia. Pathophysiology, Pharmacology, and Biochemistry of Dyskinesia 297 323 .
Megan J. Dowie, Emma L. Scotter, Emanuela Molinari & Michelle Glass. (2010) The therapeutic potential of G-protein coupled receptors in Huntington's disease. Pharmacology & Therapeutics 128:2, pages 305-323.
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Ali Jahanshahi, Rinske Vlamings, Ahmet Hilmi Kaya, Lee Wei Lim, Marcus L.F. Janssen, Sonny Tan, Veerle Visser-Vandewalle, Harry W.M. Steinbusch & Yasin Temel. (2010) Hyperdopaminergic Status in Experimental Huntington Disease. Journal of Neuropathology & Experimental Neurology 69:9, pages 910-917.
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Lan Nguyen, John L. Bradshaw, Julie C. Stout, Rodney J. Croft & Nellie Georgiou-Karistianis. (2010) Electrophysiological measures as potential biomarkers in Huntington's disease: Review and future directions. Brain Research Reviews 64:1, pages 177-194.
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