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Expert Opinion on Emerging Drugs Volume 14, 2009 - Issue 2
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Emerging drugs for esophageal cancer

Marjolein YV Homs University Medical Center Utrecht, Department of Medical Oncology, P.O. Box 85500, 3508 GA Utrecht, The Netherlands
, MD PhD,
Emile E Voest University Medical Center Utrecht, Department of Medical Oncology, P.O. Box 85500, 3508 GA Utrecht, The Netherlands
, MD PhD &
Peter D Siersema Professor University Medical Center Utrecht, Department of Gastroenterology & Hepatology, P.O. Box 85500, 3508 GA Utrecht, The Netherlands +31 88 7559338; +31 88 7555533; [email protected]
, MD PhD
Pages 329-339 | Published online: 20 May 2009

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Liu Hong, Yu Han & Lubi Brain. (2013) Epidermal growth factor receptor: an important target in esophageal cancer. Expert Opinion on Therapeutic Targets 17:10, pages 1179-1185.
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Yerlan Bahetjan, Wenqi Liu, Muguli Muhaxi, Ni Zheng, Fatemeh Sefidkon, Kejian Pang, Guangwen Shu & Xinzhou Yang. (2023) Ferula ferulaeoides ethyl acetate extract induces apoptosis in esophageal cancer cells via mitochondrial and PI3K/Akt/Bad pathways. Arabian Journal of Chemistry 16:12, pages 105291.
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Hai-Ying Cao, Xiao-Fang Guo, Xiao-Fei Zhu, Sai-Sai Li & Yong-Su Zhen. (2017) A ligand-based and enediyne-energized bispecific fusion protein targeting epidermal growth factor receptor and insulin-like growth factor-1 receptor shows potent antitumor efficacy against esophageal cancer. Oncology Reports.
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Hongfang Zhang, Conghua Xie, Jing Yue, Zhenzhen Jiang, Rongjing Zhou, Ruifei Xie, Yan Wang & Shixiu Wu. (2017) Cancer-associated fibroblasts mediated chemoresistance by a FOXO1/TGFβ1 signaling loop in esophageal squamous cell carcinoma. Molecular Carcinogenesis 56:3, pages 1150-1163.
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GANG LIN, XIAO-JIANG SUN, QIAN-BO HAN, ZHUN WANG, YA-PING XU, JIA-LEI GU, WEI WU, GU ZHANG, JIN-LIN HU, WEN-YONG SUN & WEI-MIN MAO. (2015) Epidermal growth factor receptor protein overexpression and gene amplification are associated with aggressive biological behaviors of esophageal squamous cell carcinoma. Oncology Letters 10:2, pages 901-906.
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Lei Wang, Jianfang Feng, Xiaonan Chen, Wei Guo, Yuwen Du, Yuanyuan Wang, Wenqiao Zang, Shijie Zhang & Guoqiang Zhao. (2014) Myricetin enhance chemosensitivity of 5-fluorouracil on esophageal carcinoma in vitro and in vivo. Cancer Cell International 14:1.
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Xiao-Fang Guo, Xiao-Fei Zhu, Wan-Cai Yang, Sheng-Hua Zhang & Yong-Su Zhen. (2014) An EGFR/HER2-Bispecific and Enediyne-Energized Fusion Protein Shows High Efficacy against Esophageal Cancer. PLoS ONE 9:3, pages e92986.
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X. F. Guo, X. F. Zhu, G. S. Zhong & B. G. Deng. (2013) Lapatinib, a dual inhibitor of epidermal growth factor receptor and human epidermal growth factor receptor 2, potentiates the antitumor effects of cisplatin on esophageal carcinoma. Diseases of the Esophagus 26:5, pages 487-495.
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Jian-hua Gong, Xiu-jun Liu, Yi Li & Yong-su Zhen. (2012) Pingyangmycin downregulates the expression of EGFR and enhances the effects of cetuximab on esophageal cancer cells and the xenograft in athymic mice. Cancer Chemotherapy and Pharmacology 69:5, pages 1323-1332.
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Rupert Langer, Sandra Rauser, Marcus Feith, Jörg M Nährig, Annette Feuchtinger, Helmut Friess, Heinz Höfler & Axel Walch. (2011) Assessment of ErbB2 (Her2) in oesophageal adenocarcinomas: summary of a revised immunohistochemical evaluation system, bright field double in situ hybridisation and fluorescence in situ hybridisation. Modern Pathology 24:7, pages 908-916.
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Céline Bruyère, Caroline Lonez, Anaelle Duray, Stéphanie Cludts, Jean‐Marie Ruysschaert, Sven Saussez, Paul Yeaton, Robert Kiss & Tatjana Mijatovic. (2010) Considering temozolomide as a novel potential treatment for esophageal cancer. Cancer 117:9, pages 2004-2016.
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. (2010) Current World Literature. Current Opinion in Supportive & Palliative Care 4:2, pages 111-120.
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Danny Yakoub, Oliver Priest, Akram R. George & George B. Hanna. 2010. Key Topics in Surgical Research and Methodology. Key Topics in Surgical Research and Methodology 793 814 .

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