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Emerging drugs which target the renin–angiotensin–aldosterone system

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Pages 619-630 | Published online: 12 Sep 2011

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Ludovit Paulis, Heinrich Franke & Fedor Simko. (2017) Gene therapy for hypertension. Expert Opinion on Biological Therapy 17:11, pages 1345-1361.
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Leon A Danyel, Patrick Schmerler, Ludovit Paulis, Thomas Unger & U Muscha Steckelings. (2013) Impact of AT2-receptor stimulation on vascular biology, kidney function, and blood pressure. Integrated Blood Pressure Control 6, pages 153-161.
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Thomas Mavromoustakos, George Agelis & Serdar Durdagi. (2013) AT1 antagonists: a patent review (2008 – 2012). Expert Opinion on Therapeutic Patents 23:11, pages 1483-1494.
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Anderson J Ferreira, Michael Bader & Robson AS Santos. (2012) Therapeutic targeting of the angiotensin-converting enzyme 2/Angiotensin-(1-7)/Mas cascade in the renin–angiotensin system: a patent review. Expert Opinion on Therapeutic Patents 22:5, pages 567-574.
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Koen Verdonk, A H Jan Danser & Joep H M van Esch. (2012) Angiotensin II type 2 receptor agonists: where should they be applied?. Expert Opinion on Investigational Drugs 21:4, pages 501-513.
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Articles from other publishers (19)

Ravit Cohen-Segev, Omri Nativ, Safa Kinaneh, Doron Aronson, Aviva Kabala, Shadi Hamoud, Tony Karram & Zaid Abassi. (2023) Effects of Angiotensin 1-7 and Mas Receptor Agonist on Renal System in a Rat Model of Heart Failure. International Journal of Molecular Sciences 24:14, pages 11470.
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Trupti Ghatage, Srashti Gopal Goyal, Arti Dhar & Audesh Bhat. (2021) Novel therapeutics for the treatment of hypertension and its associated complications: peptide- and nonpeptide-based strategies. Hypertension Research 44:7, pages 740-755.
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Arina Ranjit, Sana Khajehpour & Ali Aghazadeh-Habashi. (2021) Update on Angiotensin II Subtype 2 Receptor: Focus on Peptide and Nonpeptide Agonists. Molecular Pharmacology 99:6, pages 469-487.
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Omar Azzam, Marcio G. Kiuchi, Jan K. Ho, Vance B. Matthews, Leslie Marisol Lugo Gavidia, Janis M. Nolde, Revathy Carnagarin & Markus P. Schlaich. (2019) New Molecules for Treating Resistant Hypertension: a Clinical Perspective. Current Hypertension Reports 21:10.
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Paulina Pidikova, Pavel Svitok & Iveta Herichova. (2019) Sex and salt intake dependent renin-angiotensin plasticity in the liver of the rat. Endocrine Regulations 53:3, pages 178-186.
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Natalia Alenina & Michael Bader. 2019. Angiotensin-(1-7). Angiotensin-(1-7) 35 51 .
Sadashiva S. Karnik, Hamiyet Unal, Jacqueline R. Kemp, Kalyan C. Tirupula, Satoru Eguchi, Patrick M. L. Vanderheyden & Walter G. Thomas. (2015) International Union of Basic and Clinical Pharmacology. XCIX. Angiotensin Receptors: Interpreters of Pathophysiological Angiotensinergic Stimuli. Pharmacological Reviews 67:4, pages 754-819.
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Ludovit Paulis, Romana Rajkovicova & Fedor Simko. (2015) New Developments in the Pharmacological Treatment of Hypertension: Dead-End or a Glimmer at the Horizon?. Current Hypertension Reports 17:6.
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D. de Alencar Franco Costa, M. Todiras, L. A. Campos, J. Cipolla‐Neto, M. Bader & O. C. Baltatu. (2015) Sex‐dependent differences in renal angiotensinogen as an early marker of diabetic nephropathy. Acta Physiologica 213:3, pages 740-746.
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Mohamad Nasser, Nicolas Clere, Laurent Botelle, James Javellaud, Nicole Oudart, Sébastien Faure & Jean-Michel Achard. (2014) Opposite effects of angiotensins receptors type 2 and type 4 on streptozotocin induced diabetes vascular alterations in mice. Cardiovascular Diabetology 13:1.
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Michael Bader, Natalia Alenina, Miguel A. Andrade-Navarro & Robson A. Santos. (2014) Mas and Its Related G Protein–Coupled Receptors, Mrgprs. Pharmacological Reviews 66:4, pages 1080-1105.
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Robson Augusto Santos. (2014) Angiotensin-(1–7). Hypertension 63:6, pages 1138-1147.
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Enrico Vizzardi, Valentina Regazzoni, Giorgio Caretta, Mara Gavazzoni, Edoardo Sciatti, Ivano Bonadei, Eleftheria Trichaki, Riccardo Raddino & Marco Metra. (2014) Mineralocorticoid receptor antagonist in heart failure: Past, present and future perspectives. IJC Heart & Vessels 3, pages 6-14.
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Sonaz Malekzadeh, Rodrigo A. Fraga-Silva, Bram Trachet, Fabrizio Montecucco, François Mach & Nikolaos Stergiopulos. (2013) Role of the renin-angiotensin system on abdominal aortic aneurysms. European Journal of Clinical Investigation 43:12, pages 1328-1338.
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Carolyn Clarke, Monica Flores-Muñoz, Clare A McKinney, Graeme Milligan & Stuart A Nicklin. (2013) Regulation of cardiovascular remodeling by the counter-regulatory axis of the renin–angiotensin system. Future Cardiology 9:1, pages 23-38.
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Julie R. Ingelfinger. 2013. Pediatric Hypertension. Pediatric Hypertension 121 128 .
Sébastien Foulquier, U. Muscha Steckelings & Thomas Unger. (2012) Impact of the AT2 Receptor Agonist C21 on Blood Pressure and Beyond. Current Hypertension Reports 14:5, pages 403-409.
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David W. Piotrowski. (2012) Mineralocorticoid Receptor Antagonists for the Treatment of Hypertension and Diabetic Nephropathy. Journal of Medicinal Chemistry 55:18, pages 7957-7966.
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David Fournier, Friedrich C. Luft, Michael Bader, Detlev Ganten & Miguel A. Andrade-Navarro. (2012) Emergence and evolution of the renin?angiotensin?aldosterone system. Journal of Molecular Medicine 90:5, pages 495-508.
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