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Emerging drugs and combination strategies for basal cell carcinoma

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Mohd Wahid, Arshad Jawed, Sajad Ahmad Dar, Raju K Mandal & Shafiul Haque. (2017) Differential pharmacology and clinical utility of sonidegib in advanced basal cell carcinoma. OncoTargets and Therapy 10, pages 515-520.
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Nicholas J. Collier, Faisal R. Ali & John T. Lear. (2016) The safety and efficacy of sonidegib for the treatment of locally advanced basal cell carcinoma. Expert Review of Anticancer Therapy 16:10, pages 1011-1018.
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Egle Ramelyte, Valerie C. Amann & Reinhard Dummer. (2016) Sonidegib for the treatment of advanced basal cell carcinoma. Expert Opinion on Pharmacotherapy 17:14, pages 1963-1968.
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Articles from other publishers (15)

Uffe Høgh Olesen, Gael Clergeaud, Kristoffer Kjærgaard Hendel, Kelvin Yeung, Catharina Margrethe Lerche, Thomas Lars Andresen & Merete Haedersdal. (2020) Enhanced and Sustained Cutaneous Delivery of Vismodegib by Ablative Fractional Laser and Microemulsion Formulation. Journal of Investigative Dermatology 140:10, pages 2051-2059.
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Balaram S. Takale, Ruchita R. Thakore, Fan Yi Kong & Bruce H. Lipshutz. (2019) An environmentally responsible 3-pot, 5-step synthesis of the antitumor agent sonidegib using ppm levels of Pd catalysis in water. Green Chemistry 21:23, pages 6258-6262.
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Assuntina G. Sacco & Gregory A. Daniels. (2019) Adjuvant and Neoadjuvant Treatment of Skin Cancer. Facial Plastic Surgery Clinics of North America 27:1, pages 139-150.
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Andrew C. Flick, Hong X. Ding, Carolyn A. Leverett, Robert E. KyneJr.Jr., Kevin K. -C. Liu, Sarah J. Fink & Christopher J. O’Donnell. (2017) Synthetic Approaches to the New Drugs Approved During 2015. Journal of Medicinal Chemistry 60:15, pages 6480-6515.
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Erik Montagna & Otávio Sérgio Lopes. (2017) Molecular basis of basal cell carcinoma. Anais Brasileiros de Dermatologia 92:4, pages 517-520.
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Heidi J. Einolf, Jocelyn Zhou, Christina Won, Lai Wang & Sam Rebello. (2017) A Physiologically-Based Pharmacokinetic Modeling Approach To Predict Drug–Drug Interactions of Sonidegib (LDE225) with Perpetrators of CYP3A in Cancer Patients. Drug Metabolism and Disposition 45:4, pages 361-374.
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Jocelyn Zhou, Michelle Quinlan, Eunju Hurh & Dalila Sellami. (2016) Exposure-Response Analysis of Sonidegib (LDE225), an Oral Inhibitor of the Hedgehog Signaling Pathway, for Effectiveness and Safety in Patients With Advanced Solid Tumors. The Journal of Clinical Pharmacology 56:11, pages 1406-1415.
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Reinhard Dummer, Alexander Guminski, Ralf Gutzmer, Luc Dirix, Karl D. Lewis, Patrick Combemale, Robert M. Herd, Martin Kaatz, Carmen Loquai, Alexander J. Stratigos, Hans-Joachim Schulze, Ruth Plummer, Sven Gogov, Celine Pallaud, Tingting Yi, Manisha Mone, Anne Lynn S. Chang, Frank Corn?lis, Ragini Kudchadkar, Uwe Trefzer, John T. Lear, Dalila Sellami & Michael R. Migden. (2016) The 12-month analysis from Basal Cell Carcinoma Outcomes with LDE225 Treatment (BOLT): A phase II, randomized, double-blind study of sonidegib in patients with advanced basal cell carcinoma. Journal of the American Academy of Dermatology 75:1, pages 113-125.e5.
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Emilie Lauressergues, Peter Heusler, Fabrice Lestienne, David Troulier, Isabelle Rauly‐Lestienne, Amélie Tourette, Marie‐Christine Ailhaud, Claudie Cathala, Stéphanie Tardif, Delphine Denais‐Laliève, Marie‐Thérèse Calmettes, Anne‐Dominique Degryse, Antoine Dumoulin, Luc De Vries & Didier Cussac. (2016) Pharmacological evaluation of a series of smoothened antagonists in signaling pathways and after topical application in a depilated mouse model. Pharmacology Research & Perspectives 4:2.
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Susanne Rehefeldt-Erne, Mirjam C. Nägeli, Nina Winterton, Lea Felderer, Lisa Weibel, Jürg Hafner & Reinhard Dummer. (2016) Nevoid Basal Cell Carcinoma Syndrome: Report from the Zurich Nevoid Basal Cell Carcinoma Syndrome Cohort. Dermatology 232:3, pages 285-292.
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Yuji Shimizu, Tsuyoshi Ishii, Kazumasa Ogawa, Satoshi Sasaki, Hideki Matsui & Masaharu Nakayama. (2015) Biochemical characterization of smoothened receptor antagonists by binding kinetics against drug-resistant mutant. European Journal of Pharmacology 764, pages 220-227.
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Nicole Basset-Seguin, Axel Hauschild, Jean-Jacques Grob, Rainer Kunstfeld, Brigitte Dréno, Laurent Mortier, Paolo A Ascierto, Lisa Licitra, Caroline Dutriaux, Luc Thomas, Thomas Jouary, Nicolas Meyer, Bernard Guillot, Reinhard Dummer, Kate Fife, D Scott Ernst, Sarah Williams, Alberto Fittipaldo, Ioannis Xynos & Johan Hansson. (2015) Vismodegib in patients with advanced basal cell carcinoma (STEVIE): a pre-planned interim analysis of an international, open-label trial. The Lancet Oncology 16:6, pages 729-736.
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Michael R Migden, Alexander Guminski, Ralf Gutzmer, Luc Dirix, Karl D Lewis, Patrick Combemale, Robert M Herd, Ragini Kudchadkar, Uwe Trefzer, Sven Gogov, Celine Pallaud, Tingting Yi, Manisha Mone, Martin Kaatz, Carmen Loquai, Alexander J Stratigos, Hans-Joachim Schulze, Ruth Plummer, Anne Lynn S Chang, Frank Cornélis, John T Lear, Dalila Sellami & Reinhard Dummer. (2015) Treatment with two different doses of sonidegib in patients with locally advanced or metastatic basal cell carcinoma (BOLT): a multicentre, randomised, double-blind phase 2 trial. The Lancet Oncology 16:6, pages 716-728.
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Atsushi Otsuka, Mitchell P. Levesque, Reinhard Dummer & Kenji Kabashima. (2015) Hedgehog signaling in basal cell carcinoma. Journal of Dermatological Science 78:2, pages 95-100.
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B.A. AlDabagh & S.T. Arron. (2014) Advanced basal cell carcinoma: how rare is the diagnosis?. British Journal of Dermatology 171:5, pages 932-933.
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