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Emerging drugs for the treatment of knee osteoarthritis

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Win Min Oo, Shirley Pei-Chun Yu, Matthew Sean Daniel & David John Hunter. (2018) Disease-modifying drugs in osteoarthritis: current understanding and future therapeutics. Expert Opinion on Emerging Drugs 23:4, pages 331-347.
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Ting-ting Pan, Feng Pan, Wei Gao, Shan-shan Hu & Di Wang. (2021) Involvement of Macrophages and Spinal Microglia in Osteoarthritis Pain. Current Rheumatology Reports 23:5.
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Elena Rezuş, Alexandra Burlui, Anca Cardoneanu, Luana Andreea Macovei, Bogdan Ionel Tamba & Ciprian Rezuş. (2021) From Pathogenesis to Therapy in Knee Osteoarthritis: Bench-to-Bedside. International Journal of Molecular Sciences 22:5, pages 2697.
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Elijah L. Carlson, Vengadeshprabhu KaruppagounderWilliam J. Pinamont, Natalie K. Yoshioka, Adeel Ahmad, Eric M. Schott, Heather K. Le Bleu, Michael J. Zuscik, Reyad A. ElbarbaryFadia Kamal. (2021) Paroxetine-mediated GRK2 inhibition is a disease-modifying treatment for osteoarthritis. Science Translational Medicine 13:580.
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Murad Alahdal, Hui Zhang, Rongxiang Huang, Wei Sun, Zhiqin Deng, Li Duan, Hongwei Ouyang & Daping Wang. (2021) Potential efficacy of dendritic cell immunomodulation in the treatment of osteoarthritis. Rheumatology 60:2, pages 507-517.
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Laetitia S. Gaspar, Cátia Sousa, Ana Rita Álvaro, Cláudia Cavadas & Alexandrina Ferreira Mendes. (2021) Common risk factors and therapeutic targets in obstructive sleep apnea and osteoarthritis: An unexpectable link?. Pharmacological Research 164, pages 105369.
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Monir Uzzaman, Md. Kamrul Hasan, Shafi Mahmud, Kaniz Fatema & Mohammed Mahbubul Matin. (2021) Structure-based design of new diclofenac: Physicochemical, spectral, molecular docking, dynamics simulation and ADMET studies. Informatics in Medicine Unlocked 25, pages 100677.
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Jun Oike, Takayuki Okumo, Hideshi Ikemoto, Yusuke Kunieda, Shingo Nakai, Haruka Takemura, Hiroshi Takagi, Koji Kanzaki & Masataka Sunagawa. (2020) Preventive Effect of the Japanese Traditional Herbal Medicine Boiogito on Posttraumatic Osteoarthritis in Rats. Medicines 7:12, pages 74.
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Joseph C. Tsai, Grant Casteneda, Abby Lee, Kypros Dereschuk, Wei Tse Li, Jaideep Chakladar, Alecio F. Lombardi, Weg M. Ongkeko & Eric Y. Chang. (2020) Identification and Characterization of the Intra-Articular Microbiome in the Osteoarthritic Knee. International Journal of Molecular Sciences 21:22, pages 8618.
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Dongyeon J. Kim, Jun Ying & Jie Shen. 2020. Encyclopedia of Bone Biology. Encyclopedia of Bone Biology 658 675 .
Ahmet Cevik Tufan. (2019) Analogs of C-type natriuretic peptide as a potential new non-surgical treatment strategy in knee osteoarthritis. Journal of Orthopaedics 16:6, pages 522-525.
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Jie Shen, Cuicui Wang, Jun Ying, Taotao Xu, Audrey McAlinden & Regis J. O’Keefe. (2019) Inhibition of 4-aminobutyrate aminotransferase protects against injury-induced osteoarthritis in mice. JCI Insight 4:18.
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Miguel M. Garcia, Carlos Goicoechea, Martín Avellanal, Susana Traseira, Ma Isabel Martín & Eva Ma Sánchez-Robles. (2019) Comparison of the antinociceptive profiles of morphine and oxycodone in two models of inflammatory and osteoarthritic pain in rat. European Journal of Pharmacology 854, pages 109-118.
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Pedro Morouço, Cristiana Fernandes & Rita Santos-Rocha. (2019) Osteoarthritis, Exercise, and Tissue Engineering: A Stimulating Triad for Health Professionals. Journal of Aging Research 2019, pages 1-6.
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David J Hunter & Sita Bierma-Zeinstra. (2019) Osteoarthritis. The Lancet 393:10182, pages 1745-1759.
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Yen-Jung Chou, Jiunn-Jye Chuu, Yi-Jen Peng, Yu-Hsuan Cheng, Chin-Hsien Chang, Chieh-Min Chang & Hsia-Wei Liu. (2018) The potent anti-inflammatory effect of Guilu Erxian Glue extracts remedy joint pain and ameliorate the progression of osteoarthritis in mice. Journal of Orthopaedic Surgery and Research 13:1.
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Aline Garcia Ferrari, Denise Camilios Cossiolo, Marinez Kimura Peres Silva & Cristiane Franca da Silva. (2018) Osteoartrite physiopathology: review article. MOJ Orthopedics & Rheumatology 10:4.
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Zhengping Huang, Changhai Ding, Tianwang Li & Shirley Pei-Chun Yu. (2018) Current status and future prospects for disease modification in osteoarthritis. Rheumatology 57:suppl_4, pages iv108-iv123.
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Eric M. Schott, Christopher W. Farnsworth, Alex Grier, Jacquelyn A. Lillis, Sarah Soniwala, Gregory H. Dadourian, Richard D. Bell, Madison L. Doolittle, David A. Villani, Hani Awad, John P. Ketz, Fadia Kamal, Cheryl Ackert-Bicknell, John M. Ashton, Steven R. Gill, Robert A. Mooney & Michael J. Zuscik. (2018) Targeting the gut microbiome to treat the osteoarthritis of obesity. JCI Insight 3:8.
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Danial Zarringam, Joris E. J. Bekkers & Daniel B. F. Saris. (2017) Long-term Effect of Injection Treatment for Osteoarthritis in the Knee by Orthokin Autologous Conditioned Serum. CARTILAGE 9:2, pages 140-145.
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Tokio Matsuzaki, Yukio Akasaki, Merissa Olmer, Oscar Alvarez‐Garcia, Natalia Reixach, Joel N. Buxbaum & Martin K. Lotz. (2017) Transthyretin deposition promotes progression of osteoarthritis. Aging Cell 16:6, pages 1313-1322.
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Peter Wehling, Christopher Evans, Jana Wehling & William Maixner. (2017) Effectiveness of intra-articular therapies in osteoarthritis: a literature review. Therapeutic Advances in Musculoskeletal Disease 9:8, pages 183-196.
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Deva D. Chan, Jun Li, Wei Luo, Dan N. Predescu, Brian J. Cole & Anna Plaas. (2017) Pirfenidone reduces subchondral bone loss and fibrosis after murine knee cartilage injury. Journal of Orthopaedic Research.
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Qurratul-Ain Dar, Eric M. Schott, Sarah E. Catheline, Robert D. Maynard, Zhaoyang Liu, Fadia Kamal, Christopher W. Farnsworth, John P. Ketz, Robert A. Mooney, Matthew J. Hilton, Jennifer H. Jonason, Janne Prawitt & Michael J. Zuscik. (2017) Daily oral consumption of hydrolyzed type 1 collagen is chondroprotective and anti-inflammatory in murine posttraumatic osteoarthritis. PLOS ONE 12:4, pages e0174705.
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Heather K. Le Bleu, Fadia A. Kamal, Meghan Kelly, John P. Ketz, Michael J. Zuscik & Reyad A. Elbarbary. (2017) Extraction of high-quality RNA from human articular cartilage. Analytical Biochemistry 518, pages 134-138.
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Hye Won Lee, Byung-Seob Ko, Suna Kang, Jin Ah Ryuk, Min Joo Kim & Sunmin Park. (2017) Dangguijihwang-tang and Dangguijakyak-san Prevent Menopausal Symptoms and Dangguijihwang-tang Prevents Articular Cartilage Deterioration in Ovariectomized Obese Rats with Monoiodoacetate-Induced Osteoarthritis. Evidence-Based Complementary and Alternative Medicine 2017, pages 1-15.
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Angela Wang, Daniel Leong, Zhiyong He, Lin Xu, Lidi Liu, Sun Kim, David Hirsh, John Hardin, Neil Cobelli & Hui Sun. (2016) Procyanidins Mitigate Osteoarthritis Pathogenesis by, at Least in Part, Suppressing Vascular Endothelial Growth Factor Signaling. International Journal of Molecular Sciences 17:12, pages 2065.
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Hamish Osborne, Lynley Anderson, Peter Burt, Mark Young & David Gerrard. (2016) Australasian College of Sports Physicians—position statement: the place of mesenchymal stem/stromal cell therapies in sport and exercise medicine. British Journal of Sports Medicine 50:20, pages 1237-1244.
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Hamish Osborne, Lynley Anderson, Peter Burt, Mark Young & David Gerrard. (2016) Australasian College of Sports Physicians—Position Statement. Clinical Journal of Sport Medicine 26:2, pages 87-95.
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