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Expert Opinion on Therapeutic Targets Volume 13, 2009 - Issue 7
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Reviews

Effects of pharmaceuticals and other active chemicals at biological targets: mechanisms, interactions, and integration into PB-PK/PD models

Jaime Kapitulnik Hebrew University of Jerusalem, Department of Pharmacology P.O.Box 12065, Jerusalem, 91120, Israel +972 2 675 8738; +972 2 675 8741; [email protected]; David R. Bloom Center for Pharmacy and the Dr. Adolph and Klara Brettler Center for Research in Molecular Pharmacology and Therapeutics, at the School of Pharmacy, Hebrew University of Jerusalem, Israel
, PhD,
Olavi Pelkonen University of Oulu, Department of Pharmacology and Toxicology, Oulu, Finland
,
Ursula Gundert-Remy Bundesinstitut fuer Risikobewertung, Safety of Substances and Products, Berlin, Germany
,
Svein G Dahl University of Tromso, Department of Pharmacology, Tromso, Norway
&
Alan R Boobis Imperial College London, Experimental Medicine and Toxicology, London, UK
Pages 867-887 | Published online: 17 Jun 2009

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Ursula Gundert-Remy, Ulrike Bernauer, Brunhilde Blömeke, Barbara Döring, Eric Fabian, Carsten Goebel, Stefanie Hessel, Christine Jäckh, Alfonso Lampen, Franz Oesch, Ernst Petzinger, Wolfgang Völkel & Peter H. Roos. (2014) Extrahepatic metabolism at the body's internal–external interfaces. Drug Metabolism Reviews 46:3, pages 291-324.
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Charlotte Kloft & Italo Poggesi. (2010) Current and future directions of pharmacokinetic and pharmacokinetic–pharmacodynamic modelling and simulation: Population Approach Group in Europe 19th annual meeting. Expert Opinion on Drug Metabolism & Toxicology 6:12, pages 1599-1604.
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Articles from other publishers (4)

Olavi Pelkonen. (2015) Drug Metabolism - From In Vitro to In Vivo , From Simple to Complex . Basic & Clinical Pharmacology & Toxicology 117:3, pages 147-155.
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Sarah Adler, David Basketter, Stuart Creton, Olavi Pelkonen, Jan van Benthem, Valérie Zuang, Klaus Ejner Andersen, Alexandre Angers-Loustau, Aynur Aptula, Anna Bal-Price, Emilio Benfenati, Ulrike Bernauer, Jos Bessems, Frederic Y. Bois, Alan Boobis, Esther Brandon, Susanne Bremer, Thomas Broschard, Silvia Casati, Sandra Coecke, Raffaella Corvi, Mark Cronin, George Daston, Wolfgang Dekant, Susan Felter, Elise Grignard, Ursula Gundert-Remy, Tuula Heinonen, Ian Kimber, Jos Kleinjans, Hannu Komulainen, Reinhard Kreiling, Joachim Kreysa, Sofia Batista Leite, George Loizou, Gavin Maxwell, Paolo Mazzatorta, Sharon Munn, Stefan Pfuhler, Pascal Phrakonkham, Aldert Piersma, Albrecht Poth, Pilar Prieto, Guillermo Repetto, Vera Rogiers, Greet Schoeters, Michael Schwarz, Rositsa Serafimova, Hanna Tähti, Emanuela Testai, Joost van Delft, Henk van Loveren, Mathieu Vinken, Andrew Worth & José-Manuel Zaldivar. (2011) Alternative (non-animal) methods for cosmetics testing: current status and future prospects—2010. Archives of Toxicology 85:5, pages 367-485.
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Kaisa A. Salminen, Achim Meyer, Lenka Jerabkova, Laura E. Korhonen, Minna Rahnasto, Risto O. Juvonen, Peter Imming & Hannu Raunio. (2011) Inhibition of human drug metabolizing cytochrome P450 enzymes by plant isoquinoline alkaloids. Phytomedicine 18:6, pages 533-538.
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Luke A. Wittenburg & Daniel L. Gustafson. (2011) Optimizing preclinical study design in oncology research. Chemico-Biological Interactions 190:2-3, pages 73-78.
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