1,242
Views
141
CrossRef citations to date
0
Altmetric
Reviews

GLUT1 as a therapeutic target in hepatocellular carcinoma

&
Pages 1411-1427 | Published online: 30 Oct 2009

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (13)

Congyi Zhang, Zehui Liu, Feng Wang, Bin Zhang, Xirui Zhang, Peiwen Guo, Tianwei Li, Sheng Tai & Changmei Zhang. (2023) Nanomicelles for GLUT1-targeting hepatocellular carcinoma therapy based on NADPH depletion. Drug Delivery 30:1.
Read now
Jie Yao, Shuming Tang, Chenyan Shi, Yunzhi Lin, Lanlan Ge, Qinghua Chen, Baoru Ou, Dongyu Liu, Yuyang Miao, Qiujie Xie, Xudong Tang, Jia Fei, Guangyi Yang, Jun Tian & Xiaobin Zeng. (2023) Isoginkgetin, a potential CDK6 inhibitor, suppresses SLC2A1/GLUT1 enhancer activity to induce AMPK-ULK1-mediated cytotoxic autophagy in hepatocellular carcinoma. Autophagy 19:4, pages 1221-1238.
Read now
Qi Tan, Limin Duan, Qi Huang, Wenjuan Chen, Zimo Yang, Jiangbin Chen & Yang Jin. (2021) Interleukin -1β Promotes Lung Adenocarcinoma Growth and Invasion Through Promoting Glycolysis via p38 Pathway. Journal of Inflammation Research 14, pages 6491-6509.
Read now
Jiali Du, Jichun Gu, Junyuan Deng, Lei Kong, Yujie Guo, Chen Jin, Yun Bao, Deliang Fu & Ji Li. (2021) The Expression and Survival Significance of Glucose Transporter-1 in Pancreatic Cancer: Meta-Analysis, Bioinformatics Analysis and Retrospective Study. Cancer Investigation 39:9, pages 741-755.
Read now
Yu Zhang, Kaiqi Tang, Lizhu Chen, Meng Du & Zhi Qu. (2020) Exosomal CircGDI2 Suppresses Oral Squamous Cell Carcinoma Progression Through the Regulation of MiR-424-5p/SCAI Axis. Cancer Management and Research 12, pages 7501-7514.
Read now
Diyuan Zhou, Linhua Jiang, Lichen Jin, Yizhou Yao, Peijie Wang & Xinguo Zhu. (2020) Glucose Transporter-1 Cooperating with AKT Signaling Promote Gastric Cancer Progression. Cancer Management and Research 12, pages 4151-4160.
Read now
Changmei Zhang, Zhong Chen, Wenhua Li, Xiaoying Liu, Shukun Tang, Lei Jiang, Minghui Li, Haisheng Peng & Mingming Lian. (2020) Influences of different sugar ligands on targeted delivery of liposomes. Journal of Drug Targeting 28:7-8, pages 789-801.
Read now
Zhenhong Ni, Jintao He, Yaran Wu, Changjiang Hu, Xufang Dai, Xiaojing Yan, Bo Li, Xinzhe Li, Haojun Xiong, Yuming Li, Song Li, Liang Xu, Yongsheng Li, Jiqin Lian & Fengtian He. (2018) AKT-mediated phosphorylation of ATG4B impairs mitochondrial activity and enhances the Warburg effect in hepatocellular carcinoma cells. Autophagy 14:4, pages 685-701.
Read now
Ana Filipa Brito, Marina Ribeiro, Ana Margarida Abrantes, Ana Catarina Mamede, Mafalda Laranjo, João Eduardo Casalta-Lopes, Ana Cristina Gonçalves, Ana Bela Sarmento-Ribeiro, José Guilherme Tralhão & Maria Filomena Botelho. (2016) New Approach for Treatment of Primary Liver Tumors: The Role of Quercetin. Nutrition and Cancer 68:2, pages 250-266.
Read now
Håkon Reikvam, Michelle Hauge, Annette K Brenner, Kimberley Joanne Hatfield & Øystein Bruserud. (2015) Emerging therapeutic targets for the treatment of human acute myeloid leukemia (part 1) – gene transcription, cell cycle regulation, metabolism and intercellular communication. Expert Review of Hematology 8:3, pages 299-313.
Read now
June-Hyung Kim, Hee Young Kim, Young-Kyoung Lee, Young-Sil Yoon, Wei Guang Xu, Joon-Kee Yoon, Sung-E Choi, Young-Gyu Ko, Min-Jung Kim, Su-Jae Lee, Hee-Jung Wang & Gyesoon Yoon. (2011) Involvement of mitophagy in oncogenic K-Ras-induced transformation. Autophagy 7:10, pages 1187-1198.
Read now
Thomas Amann, Georgi Kirovski, Anja Kathrin Bosserhoff & Claus Hellerbrand. (2011) Analysis of a promoter polymorphism of the GLUT1 gene in patients with hepatocellular carcinoma. Molecular Membrane Biology 28:3, pages 182-186.
Read now

Articles from other publishers (128)

Dongping Li, Xiahui Lin, Jiale Li, Xinyi Liu, Feng Zhang, Wenqing Tang, Si Zhang, Ling Dong & Ruyi Xue. (2023) Eleven metabolism‑related genes composed of Stard5 predict prognosis and contribute to EMT phenotype in HCC. Cancer Cell International 23:1.
Crossref
Josipa Kokeza, Ante Strikic, Marin Ogorevc, Nela Kelam, Martina Vukoja, Ivo Dilber & Sandra Zekic Tomas. (2023) The Effect of GLUT1 and HIF-1α Expressions on Glucose Uptake and Patient Survival in Non-Small-Cell Lung Carcinoma. International Journal of Molecular Sciences 24:13, pages 10575.
Crossref
Qian Wang, Wei Yu, Tao Wang & Changshan Huang. (2023) Circular RNA circDLG1 contributes to HCC progression by regulating the miR-141-3p/WTAP axis. Functional & Integrative Genomics 23:2.
Crossref
Lei Meng, Fangshu Liu, Chenchen Du, Jiaying Zhu, Qian Xiong, Jing Li & Weitong Sun. (2023) Glucosamine-Modified Reduction-Responsive Polymeric Micelles for Liver Cancer Therapy. Molecules 28:9, pages 3824.
Crossref
Davide Gnocchi, Carlo Sabbà, Mara Massimi & Antonio Mazzocca. (2023) Metabolism as a New Avenue for Hepatocellular Carcinoma Therapy. International Journal of Molecular Sciences 24:4, pages 3710.
Crossref
Qing Peng, Liyuan Hao, Yinglin Guo, Zhiqin Zhang, Jingmin Ji, Yu Xue, Yiwei Liu, Caige Li, Junlan Lu & Xinli Shi. (2022) Dihydroartemisinin inhibited the Warburg effect through YAP1/SLC2A1 pathway in hepatocellular carcinoma. Journal of Natural Medicines 77:1, pages 28-40.
Crossref
Junliang Chen, Huaitao Wang, Lei Zhou, Zhihao Liu, Hui Chen & Xiaodong Tan. (2022) A necroptosis‐related gene signature for predicting prognosis, immune landscape, and drug sensitivity in hepatocellular carcinoma. Cancer Medicine 11:24, pages 5079-5096.
Crossref
Xinhua Guo, Bowen Zheng, Jiahui Wang, Tiejian Zhao & Yang Zheng. (2022) Exploring the mechanism of action of Chinese medicine in regulating liver fibrosis based on the alteration of glucose metabolic pathways. Phytotherapy Research.
Crossref
Xia CuiJiming ChenYafeng ZhengHuaji Shen. (2022) Circ_0000745 Promotes the Progression of Cervical Cancer by Regulating miR-409-3p/ATF1 Axis. Cancer Biotherapy and Radiopharmaceuticals 37:9, pages 766-778.
Crossref
Lin Zhou, Yang Zhao, Li-Chao Pan, Jing Wang, Xian-Jie Shi, Guo-Sheng Du & Qiang He. (2022) Sirolimus increases the anti-cancer effect of Huai Er by regulating hypoxia inducible factor-1α-mediated glycolysis in hepatocellular carcinoma. World Journal of Gastroenterology 28:32, pages 4600-4619.
Crossref
Natarajaseenivasan Suriya Muthukumaran, Prema Velusamy, Charles Solomon Akino Mercy, Dianne Langford, Kalimuthusamy Natarajaseenivasan & Santhanam Shanmughapriya. (2022) MicroRNAs as Regulators of Cancer Cell Energy Metabolism. Journal of Personalized Medicine 12:8, pages 1329.
Crossref
Andreia P Alves, Sandra M Rocha, Ana C Mamede, Patrícia C Braga, Marco G Alves, Pedro F Oliveira, Filomena M Botelho & Cláudio J Maia. (2022) Differential response of hepatocellular carcinoma glycolytic metabolism and oxidative stress markers after exposure to human amniotic membrane proteins. Molecular Biology Reports 49:8, pages 7731-7741.
Crossref
Negin Karamali, Samaneh Ebrahimnezhad, Reihaneh Khaleghi Moghadam, Niloofar Daneshfar & Alireza Rezaiemanesh. (2022) HRD1 in human malignant neoplasms: Molecular mechanisms and novel therapeutic strategy for cancer. Life Sciences 301, pages 120620.
Crossref
Fengjie Bie, Guijuan Zhang, Xianxin Yan, Xinyi Ma, Sha Zhan, Yebei Qiu, Jingyu Cao, Yi Ma & Min Ma. (2022) β-Boswellic Acid Suppresses Breast Precancerous Lesions via GLUT1 Targeting-Mediated Glycolysis Inhibition and AMPK Pathway Activation. Frontiers in Oncology 12.
Crossref
Nan Wang, Shuo Zhang, Yafei Yuan, Hanwen Xu, Elisabeth Defossa, Hans Matter, Melissa Besenius, Volker Derdau, Matthias Dreyer, Nis Halland, Kaihui Hu He, Stefan Petry, Michael Podeschwa, Norbert Tennagels, Xin Jiang & Nieng Yan. (2022) Molecular basis for inhibiting human glucose transporters by exofacial inhibitors. Nature Communications 13:1.
Crossref
Yan Lan, Chaonan Jin, Pavitra Kumar, Xia Yu, Cameron Lenahan & Jifang Sheng. (2022) Ketogenic Diets and Hepatocellular Carcinoma. Frontiers in Oncology 12.
Crossref
Jia Xu, Xi Li, Purong Zhang, Jie Luo, Exian Mou & Shiwei Liu. (2022) miR‑143‑5p suppresses breast cancer progression by targeting the HIF‑1α‑related GLUT1 pathway. Oncology Letters 23:5.
Crossref
Jennifer Riedel, Matias Pibuel, Ezequiel Bernabeu, Daniela Poodts, Mariangeles Díaz, Miguel Allo, Luciano Parola, Silvia Hajos, Juan Manuel Lázaro-Martínez, María Jimena Salgueiro, Yanina Santander, Silvina Lompardía, Marcela A. Moretton, Christian Höcht & Diego A. Chiappetta. (2022) Glycosylated paclitaxel mixed nanomicelles: Increasing drug brain accumulation and enhancing its in vitro antitumoral activity in glioblastoma cell lines. Journal of Drug Delivery Science and Technology 68, pages 103046.
Crossref
Xia Zheng, Yudong Gou, Ziyu Jiang, Aizhen Yang, Zhihui Yang & Shukui Qin. (2021) Icaritin-Induced FAM99A Affects GLUT1-Mediated Glycolysis via Regulating the JAK2/STAT3 Pathway in Hepatocellular Carcinoma. Frontiers in Oncology 11.
Crossref
Gayeon Kim, Seyeon Lim & Kwang Dong Kim. (2021) N-myc Downstream-Regulated Gene 2 (NDRG2) Function as a Positive Regulator of Apoptosis: A New Insight into NDRG2 as a Tumor Suppressor. Cells 10:10, pages 2649.
Crossref
Wei Jiang, Xingyu Luo, Lulu Wei, Shanmei Yuan, Jianfeng Cai, Xiqun Jiang & Yong Hu. (2021) The Sustainability of Energy Conversion Inhibition for Tumor Ferroptosis Therapy and Chemotherapy. Small 17:38, pages 2102695.
Crossref
Xu Cheng, Yingran Xu, Yong Zhang, Chaochao Jia, Bing Wei, Ting Hu, Rupei Tang & Conghu Li. (2021) Glucose-Targeted Hydroxyapatite/Indocyanine Green Hybrid Nanoparticles for Collaborative Tumor Therapy. ACS Applied Materials & Interfaces 13:31, pages 37665-37679.
Crossref
Xinlong Zang, Mingyang Cheng, Xiaoxu Zhang & Xuehong Chen. (2021) Quercetin nanoformulations: a promising strategy for tumor therapy. Food & Function 12:15, pages 6664-6681.
Crossref
Yi-Te Lee, Benjamin V. Tran, Jasmine J. Wang, Icy Y. Liang, Sungyong You, Yazhen Zhu, Vatche G. Agopian, Hsian-Rong Tseng & Ju Dong Yang. (2021) The Role of Extracellular Vesicles in Disease Progression and Detection of Hepatocellular Carcinoma. Cancers 13:12, pages 3076.
Crossref
Ai-Mei Li, Xia-Wen Lin, Jing-Tao Shen, Min Li, Qi-Huang Zheng, Zheng-Yang Zhou & Ming Shi. (2021) HRD1 attenuates the high uptake of [18F]FDG in hepatocellular carcinoma PET imaging. Nuclear Medicine and Biology 96-97, pages 27-34.
Crossref
Ning Ding, Shengjun Xu, Sheng Zheng, Qianwei Ye, Li Xu, Sunbin Ling, Shanshan Xie, Wenwen Chen, Zizhen Zhang, Meng Xue, Zhenghua Lin, Xiao Xu & Liangjing Wang. (2021) “Sweet tooth”-oriented SN38 prodrug delivery nanoplatform for targeted gastric cancer therapy. Journal of Materials Chemistry B 9:12, pages 2816-2830.
Crossref
Aliaa A. Alamoudi. (2021) Why do cancer cells break from host circadian rhythm? Insights from unicellular organisms. BioEssays 43:4, pages 2000205.
Crossref
Haoming Xia, Ziyue Huang, Shuqiang Liu, Xudong Zhao, Risheng He, Zhongrui Wang, Wenguang Shi, Wangming Chen, Zhizhou Li, Liang Yu, Peng Huang, Pengcheng Kang, Zhilei Su, Yi Xu, Judy Wai Ping Yam & Yunfu Cui. (2021) Exosomal Non-Coding RNAs: Regulatory and Therapeutic Target of Hepatocellular Carcinoma. Frontiers in Oncology 11.
Crossref
Xiaoqing Luo, Enze Zheng, Li Wei, Han Zeng, Hong Qin, Xiaoyu Zhang, Meng Liao, Lin Chen, Lei Zhao, Xiong Z. Ruan, Ping Yang & Yaxi Chen. (2021) The fatty acid receptor CD36 promotes HCC progression through activating Src/PI3K/AKT axis-dependent aerobic glycolysis. Cell Death & Disease 12:4.
Crossref
Parth Trivedi, Shuang Wang & Scott L. Friedman. (2021) The Power of Plasticity—Metabolic Regulation of Hepatic Stellate Cells. Cell Metabolism 33:2, pages 242-257.
Crossref
Feodora Roxanne Kosasih & Benjamin Bonavida. 2021. YY1 in the Control of the Pathogenesis and Drug Resistance of Cancer. YY1 in the Control of the Pathogenesis and Drug Resistance of Cancer 271 287 .
Sminu Bose, Cissy Zhang & Anne Le. 2021. The Heterogeneity of Cancer Metabolism. The Heterogeneity of Cancer Metabolism 3 15 .
Chunyue Wang, Zhong Chen, Xuefeng Tang, Xiaoying Liu, Wang Na, Wenhua Li & Ting Liu. (2020) Influences of galactose ligand on the uptake of TADF liposomes by HepG2 cells. Photodiagnosis and Photodynamic Therapy 32, pages 102014.
Crossref
Shuo Shen, Maobo Du, Qingbo Liu, Peng Gao, Jigang Wang, Shuzhi Liu & Liwei Gu. (2020) Development of GLUT1-targeting alkyl glucoside-modified dihydroartemisinin liposomes for cancer therapy. Nanoscale 12:42, pages 21901-21912.
Crossref
Kalpana Tilekar, Neha Upadhyay, Markus Schweipert, Jessica D. Hess, Lucasantiago Henze Macias, Piotr Mrowka, Franz-Josef Meyer-Almes, Renato J. Aguilera, Cristina V. Iancu, Jun-yong Choe & C.S. Ramaa. (2020) Permuted 2,4-thiazolidinedione (TZD) analogs as GLUT inhibitors and their in-vitro evaluation in leukemic cells. European Journal of Pharmaceutical Sciences 154, pages 105512.
Crossref
Miguel Sampedro-Núñez, Antonio Bouthelier, Ana Serrano-Somavilla, Rebeca Martínez-Hernández, Magdalena Adrados, Elena Martín-Pérez, José Luis Muñoz de Nova, José Manuel Cameselle-Teijeiro, Concepción Blanco-Carrera, José Manuel Cabezas-Agricola, José Ángel Díaz, Rogelio García-Centeno, Julian Aragones & Mónica Marazuela. (2020) LAT-1 and GLUT-1 Carrier Expression and Its Prognostic Value in Gastroenteropancreatic Neuroendocrine Tumors. Cancers 12:10, pages 2968.
Crossref
Yuan-Hsi Wang, Fat-Moon Suk & Yi-Jen Liao. (2020) Loss of HMGCS2 Enhances Lipogenesis and Attenuates the Protective Effect of the Ketogenic Diet in Liver Cancer. Cancers 12:7, pages 1797.
Crossref
Xin Meng, Xujing Lian, Xiao Li, Qiang Ya, Tingshen Li, Yongmin Zhang, Yang Yang & Yan Zhang. (2020) Synthesis of 2′-paclitaxel 2-deoxy-2-fluoro-glucopyranosyl carbonate for specific targeted delivery to cancer cells. Carbohydrate Research 493, pages 108034.
Crossref
Wenlei Zhao, Hongliang Wei, Fengjie Liu & Chao Ran. (2020) Glucose ligand modififed thermally activated delayed fluorescence targeted nanoprobe for malignant cells imaging diagnosis. Photodiagnosis and Photodynamic Therapy 30, pages 101744.
Crossref
Weiting Kang, Meng Zhang, Qiang Wang, Da Gu, Zhilong Huang, Hanbo Wang, Yuzhu Xiang, Qinghua Xia, Zilian Cui & Xunbo Jin. (2020) The SLC Family Are Candidate Diagnostic and Prognostic Biomarkers in Clear Cell Renal Cell Carcinoma. BioMed Research International 2020, pages 1-17.
Crossref
Kishor Pant, Seth Richard, Estanislao Peixoto & Sergio A Gradilone. (2020) Role of Glucose Metabolism Reprogramming in the Pathogenesis of Cholangiocarcinoma. Frontiers in Medicine 7.
Crossref
Wenbo Li & Jin Wang. (2020) Uncovering the Underlying Mechanisms of Cancer Metabolism through the Landscapes and Probability Flux Quantifications. iScience 23:4, pages 101002.
Crossref
Christopher S. Chambers, Jitka Viktorová, Kateřina Řehořová, David Biedermann, Lucie Turková, Tomáš Macek, Vladimír Křen & Kateřina Valentová. (2019) Defying Multidrug Resistance! Modulation of Related Transporters by Flavonoids and Flavonolignans. Journal of Agricultural and Food Chemistry 68:7, pages 1763-1779.
Crossref
Andreas Kroh, Jeanette Walter, Herdit Schüler, Jochen Nolting, Roman Eickhoff, Daniel Heise, Ulf Peter Neumann, Thorsten Cramer, Tom Florian Ulmer & Athanassios Fragoulis. (2019) A Newly Established Murine Cell Line as a Model for Hepatocellular Cancer in Non-Alcoholic Steatohepatitis. International Journal of Molecular Sciences 20:22, pages 5658.
Crossref
Juan Li, Tongxin Wang, Jun Xia, Weilei Yao & Feiruo Huang. (2019) Enzymatic and nonenzymatic protein acetylations control glycolysis process in liver diseases. The FASEB Journal 33:11, pages 11640-11654.
Crossref
Natalia Siwecka, Wioletta Rozpędek, Dariusz Pytel, Adam Wawrzynkiewicz, Adam Dziki, Łukasz Dziki, J. Alan Diehl & Ireneusz Majsterek. (2019) Dual role of Endoplasmic Reticulum Stress-Mediated Unfolded Protein Response Signaling Pathway in Carcinogenesis. International Journal of Molecular Sciences 20:18, pages 4354.
Crossref
Angara Zambrano, Matías Molt, Elena Uribe & Mónica Salas. (2019) Glut 1 in Cancer Cells and the Inhibitory Action of Resveratrol as A Potential Therapeutic Strategy. International Journal of Molecular Sciences 20:13, pages 3374.
Crossref
Lu Wan, Tian Xia, Yanqin Du, Jie Liu, Yuyu Xie, Yijie Zhang, Fei Guan, Jun Wu, Xiaochuan Wang & Chunwei Shi. (2019) Exosomes from activated hepatic stellate cells contain GLUT1 and PKM2: a role for exosomes in metabolic switch of liver nonparenchymal cells. The FASEB Journal 33:7, pages 8530-8542.
Crossref
Qin Guo, Chao Li, Wenxi Zhou, Xinli Chen, Yu Zhang, Yifei Lu, Yujie Zhang, Qinjun Chen, Donghui Liang, Tao Sun & Chen Jiang. (2019) GLUT1-mediated effective anti-miRNA21 pompon for cancer therapy. Acta Pharmaceutica Sinica B 9:4, pages 832-842.
Crossref
Fuliang Bai, Ze Yu, Xin Gao, Jiawei Gong, Lizhi Fan & Feifei Liu. (2019) Simvastatin induces breast cancer cell death through oxidative stress up-regulating miR-140-5p. Aging 11:10, pages 3198-3219.
Crossref
Anna Walczak, Kinga Gradzik, Jacek Kabzinski, Karolina Przybylowska-Sygut & Ireneusz Majsterek. (2019) The Role of the ER-Induced UPR Pathway and the Efficacy of Its Inhibitors and Inducers in the Inhibition of Tumor Progression. Oxidative Medicine and Cellular Longevity 2019, pages 1-15.
Crossref
A.P. Alves, A.C. Mamede, M.G. Alves, P.F. Oliveira, S.M. Rocha, M.F. Botelho & C.J. Maia. (2018) Glycolysis Inhibition as a Strategy for Hepatocellular Carcinoma Treatment?. Current Cancer Drug Targets 19:1, pages 26-40.
Crossref
Serena De Matteis, Andrea Ragusa, Giorgia Marisi, Stefania De Domenico, Andrea Casadei Gardini, Massimiliano Bonafè & Anna Maria Giudetti. (2018) Aberrant Metabolism in Hepatocellular Carcinoma Provides Diagnostic and Therapeutic Opportunities. Oxidative Medicine and Cellular Longevity 2018, pages 1-13.
Crossref
Dmitry Shishmarev, Clément Q. Fontenelle, Ilya Kuprov, Bruno Linclau & Philip W. Kuchel. (2018) Transmembrane Exchange of Fluorosugars: Characterization of Red Cell GLUT1 Kinetics Using 19F NMR. Biophysical Journal 115:10, pages 1906-1919.
Crossref
Qiuran Xu, Changwei Dou, Xin Liu, Liu Yang, Chao Ni, Jiahui Wang, Yang Guo, Wei Yang, Xiangmin Tong & Dongsheng Huang. (2018) Oviductus ranae protein hydrolysate (ORPH) inhibits the growth, metastasis and glycolysis of HCC by targeting miR-491-5p/PKM2 axis. Biomedicine & Pharmacotherapy 107, pages 1692-1704.
Crossref
Bo Chen, Yang-Min Zheng & Jing-Pu Zhang. (2018) Comparative Study of Different Diets-Induced NAFLD Models of Zebrafish. Frontiers in Endocrinology 9.
Crossref
Li Yin, Zhihui Cai, Baoan Zhu & Cunshuan Xu. (2018) Identification of Key Pathways and Genes in the Dynamic Progression of HCC Based on WGCNA. Genes 9:2, pages 92.
Crossref
Haojun Ma & Chen Jiang. (2018) Dehydroascorbic Acid and pGPMA Dual Modified pH-Sensitive Polymeric Micelles for Target Treatment of Liver Cancer. Journal of Pharmaceutical Sciences 107:2, pages 595-603.
Crossref
Jeong Yong Jeon, Misu Lee, Sang Hyun Whang, Jung-Whan Kim, Arthur Cho & Mijin Yun. (2018) Regulation of Acetate Utilization by Monocarboxylate Transporter 1 (MCT1) in Hepatocellular Carcinoma (HCC). Oncology Research Featuring Preclinical and Clinical Cancer Therapeutics 26:1, pages 71-81.
Crossref
Anna Choromańska, Jolanta Saczko, Sandra Łubińska, Anna Szewczyk & Julita Kulbacka. (2018) WITHDRAWN: Mechanisms of antimelanoma effect of oat β-glucan supported by electroporation. Bioelectrochemistry.
Crossref
Sminu Bose & Anne Le. 2018. The Heterogeneity of Cancer Metabolism. The Heterogeneity of Cancer Metabolism 3 12 .
Yi Zhou, Huaying Wen, Liang Gu, Jijun Fu, Jiayi Guo, Lingran Du, Xiaoqin Zhou, Xiyong Yu, Yugang Huang & He Wang. (2017) Aminoglucose-functionalized, redox-responsive polymer nanomicelles for overcoming chemoresistance in lung cancer cells. Journal of Nanobiotechnology 15:1.
Crossref
Peter Bannasch, Silvia Ribback, Qin Su & Doris Mayer. (2017) Clear cell hepatocellular carcinoma: origin, metabolic traits and fate of glycogenotic clear and ground glass cells. Hepatobiliary & Pancreatic Diseases International 16:6, pages 570-594.
Crossref
Satoshi Hyuga, Hiroshi Wada, Hidetoshi Eguchi, Toru Otsuru, Yoshifumi Iwgami, Daisaku Yamada, Takehiro Noda, Tadafumi Asaoka, Koichi Kawamoto, Kunihito Gotoh, Yutaka Takeda, Masahiro Tanemura, Koji Umeshita, Yuichiro Doki & Masaki Mori. (2017) Expression of carbonic anhydrase IX is associated with poor prognosis through regulation of the epithelial-mesenchymal transition in hepatocellular carcinoma. International Journal of Oncology 51:4, pages 1179-1190.
Crossref
Céline Pinheiro, Sara Granja, Adhemar Longatto-Filho, André M. Faria, Maria C.B.V. Fragoso, Silvana M. Lovisolo, Murilo Bonatelli, Ricardo F.A. Costa, Antonio M. Lerário, Madson Q. Almeida, Fátima Baltazar & Maria C.N. Zerbini. (2017) GLUT1 expression in pediatric adrenocortical tumors: a promising candidate to predict clinical behavior. Oncotarget 8:38, pages 63835-63845.
Crossref
Nieng Yan. (2017) A Glimpse of Membrane Transport through Structures—Advances in the Structural Biology of the GLUT Glucose Transporters. Journal of Molecular Biology 429:17, pages 2710-2725.
Crossref
C Xu, X Yang, Y Wang, N Ding, R Han, Y Sun & Y Wang. (2017) An analysis of the polymorphisms of the GLUT1 gene in urothelial cell carcinomas of the bladder and its correlation with p53, Ki67 and GLUT1 expressions. Cancer Gene Therapy 24:7, pages 297-303.
Crossref
Jihae Shin, Ki Young Paek, Maria Ivshina, Emily E. Stackpole & Joel D. Richter. (2017) Essential role for non-canonical poly(A) polymerase GLD4 in cytoplasmic polyadenylation and carbohydrate metabolism. Nucleic Acids Research 45:11, pages 6793-6804.
Crossref
Xiangfu Ding, Jingjing Liu, Tianzhou Liu, Zhiming Ma, Dacheng Wen & Jiaming Zhu. (2017) miR-148b inhibits glycolysis in gastric cancer through targeting SLC2A1. Cancer Medicine 6:6, pages 1301-1310.
Crossref
Li-Fang Shen, Xin Zhao, Shui-Hong Zhou, Zhong-Jie Lu, Kui Zhao, Jun Fan & Min-Li Zhou. (2017) In vivo evaluation of the effects of simultaneous inhibition of GLUT-1 and HIF-1α by antisense oligodeoxynucleotides on the radiosensitivity of laryngeal carcinoma using micro 18F-FDG PET/CT . Oncotarget 8:21, pages 34709-34726.
Crossref
André Medina, Marcin Banaszczak, Yang Ni, Ina Aretz & David Meierhofer. (2017) ρ0 Cells Feature De-Ubiquitination of SLC Transporters and Increased Levels and Fluxes of Amino Acids. International Journal of Molecular Sciences 18:4, pages 879.
Crossref
Xiaoyu Pei, Feifei Luo, Jun Zhang, Wulian Chen, Chen Jiang & Jie Liu. (2017) Dehydroascorbic Acids-modified Polymer Micelles Target Cancer Cells to Enhance Anti-tumor Efficacy of Paclitaxel. Scientific Reports 7:1.
Crossref
Xianfeng Zeng, Peiyao Wu, Chengbo Yao, Jiaqi Liang, Shuting Zhang & Hang Yin. (2017) Small Molecule and Peptide Recognition of Protein Transmembrane Domains. Biochemistry 56:15, pages 2076-2085.
Crossref
Yu Zhang, Qin Guo, Sai An, Yifei Lu, Jianfeng Li, Xi He, Lisha Liu, Yujie Zhang, Tao Sun & Chen Jiang. (2017) ROS-Switchable Polymeric Nanoplatform with Stimuli-Responsive Release for Active Targeted Drug Delivery to Breast Cancer. ACS Applied Materials & Interfaces 9:14, pages 12227-12240.
Crossref
Chengyuan Peng, Slávka Kaščáková, Franck Chiappini, Natalia Olaya, Christophe Sandt, Ibraheem Yousef, Didier Samuel, Paul Dumas, Catherine Guettier & François Le Naour. (2016) Discrimination of cirrhotic nodules, dysplastic lesions and hepatocellular carcinoma by their vibrational signature. Journal of Translational Medicine 14:1.
Crossref
Holger Siebeneicher, Arwed Cleve, Hartmut Rehwinkel, Roland Neuhaus, Iring Heisler, Thomas Müller, Marcus Bauser & Bernd Buchmann. (2016) Identification and Optimization of the First Highly Selective GLUT1 Inhibitor BAY-876. ChemMedChem 11:20, pages 2261-2271.
Crossref
Camille Lehuédé, Fanny Dupuy, Rebecca Rabinovitch, Russell G. Jones & Peter M. Siegel. (2016) Metabolic Plasticity as a Determinant of Tumor Growth and Metastasis. Cancer Research 76:18, pages 5201-5208.
Crossref
Jinqiang Zhang, Melody Baddoo, Chang Han, Michael J. Strong, Jennifer Cvitanovic, Krzysztof Moroz, Srikanta Dash, Erik K. Flemington & Tong Wu. (2016) Gene network analysis reveals a novel 22-gene signature of carbon metabolism in hepatocellular carcinoma. Oncotarget 7:31, pages 49232-49245.
Crossref
CHUANYI ZHENG, KUN YANG, MAOYING ZHANG, MINGMING ZOU, ENQI BAI, QUANHONG MA & RUXIANG XU. (2016) Specific protein 1 depletion attenuates glucose uptake and proliferation of human glioma cells by regulating GLUT3 expression. Oncology Letters 12:1, pages 125-131.
Crossref
A Garufi, D Trisciuoglio, M Cirone & G D'Orazi. (2016) ZnCl2 sustains the adriamycin-induced cell death inhibited by high glucose. Cell Death & Disease 7:6, pages e2280-e2280.
Crossref
Yangzom D. BhutiaEllappan BabuSabarish RamachandranShengping YangMuthusamy ThangarajuVadivel Ganapathy. (2016) SLC transporters as a novel class of tumour suppressors: identity, function and molecular mechanisms. Biochemical Journal 473:9, pages 1113-1124.
Crossref
Khyati KapoorJanet S. Finer-MooreBjørn P. PedersenLaura CaboniAndrew WaightRoman C. HilligPeter BringmannIring Heisler, Thomas Müller, Holger SiebeneicherRobert M. Stroud. (2016) Mechanism of inhibition of human glucose transporter GLUT1 is conserved between cytochalasin B and phenylalanine amides. Proceedings of the National Academy of Sciences 113:17, pages 4711-4716.
Crossref
Holger Siebeneicher, Marcus Bauser, Bernd Buchmann, Iring Heisler, Thomas Müller, Roland Neuhaus, Hartmut Rehwinkel, Joachim Telser & Ludwig Zorn. (2016) Identification of novel GLUT inhibitors. Bioorganic & Medicinal Chemistry Letters 26:7, pages 1732-1737.
Crossref
Runze Shang, Jianlin Wang, Wei Sun, Bin Dai, Bai Ruan, Zhuochao Zhang, Xisheng Yang, Yuan Gao, Shibin Qu, Xing Lv, Kaishan Tao, Lin Wang, Kefeng Dou & Desheng Wang. (2015) RRAD inhibits aerobic glycolysis, invasion, and migration and is associated with poor prognosis in hepatocellular carcinoma. Tumor Biology 37:4, pages 5097-5105.
Crossref
Dong Deng & Nieng Yan. (2016) GLUT, SGLT, and SWEET: Structural and mechanistic investigations of the glucose transporters. Protein Science 25:3, pages 546-558.
Crossref
Yuanyuan Liu, Yuyan Zhao & Lei Guo. (2016) Effects of orexin A on glucose metabolism in human hepatocellular carcinoma in vitro via PI3K/Akt/mTOR-dependent and -independent mechanism. Molecular and Cellular Endocrinology 420, pages 208-216.
Crossref
Andreas Koch, Sven Arke Lang, Peter Johannes Wild, Susanne Gantner, Abdo Mahli, Gerrit Spanier, Mark Berneburg, Martina Müller, Anja Katrin Bosserhoff & Claus Hellerbrand. (2015) Glucose transporter isoform 1 expression enhances metastasis of malignant melanoma cells. Oncotarget 6:32, pages 32748-32760.
Crossref
Dong Deng, Pengcheng Sun, Chuangye Yan, Meng Ke, Xin Jiang, Lei Xiong, Wenlin Ren, Kunio Hirata, Masaki Yamamoto, Shilong Fan & Nieng Yan. (2015) Molecular basis of ligand recognition and transport by glucose transporters. Nature 526:7573, pages 391-396.
Crossref
Ana F. Brito, Ana M. Abrantes, Marina Ribeiro, Rui Oliveira, João Casalta-Lopes, Ana C. Gonçalves, Ana B. Sarmento-Ribeiro, José G. Tralhão & Maria F. Botelho. (2015) Fluorine-18 Fluorodeoxyglucose Uptake in Hepatocellular Carcinoma: Correlation with Glucose Transporters and p53 Expression. Journal of Clinical and Experimental Hepatology 5:3, pages 183-189.
Crossref
Carmen Oi-ning Leung, Carmen Chak-lui Wong, Dorothy Ngo-yin Fan, Alan Ka-lun Kai, Edmund Kwok-kwan Tung, Iris Ming-jing Xu, Irene Oi-lin Ng & Regina Cheuk-lam Lo. (2015) PIM1 regulates glycolysis and promotes tumor progression in hepatocellular carcinoma. Oncotarget 6:13, pages 10880-10892.
Crossref
Chiao-Fang Teng, Wen-Chuan Hsieh, Han-Chieh Wu, Yih-Jyh Lin, Hung-Wen Tsai, Wenya Huang & Ih-Jen Su. (2015) Hepatitis B Virus Pre-S2 Mutant Induces Aerobic Glycolysis through Mammalian Target of Rapamycin Signal Cascade. PLOS ONE 10:4, pages e0122373.
Crossref
Yubo Guo, Yujie Zhang, Jianfeng Li, Yu Zhang, Yifei Lu, Xutao Jiang, Xi He, Haojun Ma, Sai An & Chen Jiang. (2015) Cell Microenvironment-Controlled Antitumor Drug Releasing-Nanomicelles for GLUT1-Targeting Hepatocellular Carcinoma Therapy. ACS Applied Materials & Interfaces 7:9, pages 5444-5453.
Crossref
Cuiyun Huang, Huan Qin, Jun Qian, Jingye Zhang, Shengyuan Zhao, Yinzhi Changyi, Bingbing Li, Jianping Zhang, Jianhua Zhu, Da Xing, Sihua Yang & Cong Li. (2015) Multi-parametric imaging of the invasiveness-permissive acidic microenvironment in human glioma xenografts. RSC Advances 5:69, pages 55669-55677.
Crossref
Surendra K Shukla, Teklab Gebregiworgis, Vinee Purohit, Nina V Chaika, Venugopal Gunda, Prakash Radhakrishnan, Kamiya Mehla, Iraklis I Pipinos, Robert Powers, Fang Yu & Pankaj K Singh. (2014) Metabolic reprogramming induced by ketone bodies diminishes pancreatic cancer cachexia. Cancer & Metabolism 2:1.
Crossref
Ana F. Brito, Mónica Mendes, Ana M. Abrantes, José G. Tralhão & Maria F. Botelho. (2014) Positron Emission Tomography Diagnostic Imaging in Multidrug-Resistant Hepatocellular Carcinoma: Focus on 2-Deoxy-2-(18F)Fluoro-d-Glucose. Molecular Diagnosis & Therapy 18:5, pages 495-504.
Crossref
Yuichiro Kubo, Shinichi Aishima, Yuki Tanaka, Koji Shindo, Yusuke Mizuuchi, Koichiro Abe, Ken Shirabe, Yoshihiko Maehara, Hiroshi Honda & Yoshinao Oda. (2014) Different expression of glucose transporters in the progression of intrahepatic cholangiocarcinoma. Human Pathology 45:8, pages 1610-1617.
Crossref
Dong Deng, Chao Xu, Pengcheng Sun, Jianping Wu, Chuangye Yan, Mingxu Hu & Nieng Yan. (2014) Crystal structure of the human glucose transporter GLUT1. Nature 510:7503, pages 121-125.
Crossref
Pan Sun, Jun-Wei Hu, Wu-Jun Xiong & Jun Mi. (2014) miR-186 Regulates Glycolysis through Glut1 During the Formation of Cancer-associated Fibroblasts. Asian Pacific Journal of Cancer Prevention 15:10, pages 4245-4250.
Crossref
Ola D. Alabi, Stephen M. Gunnink, Benjamin D. Kuiper, Samuel A. Kerk, Emily Braun & Larry L. Louters. (2014) Osthole activates glucose uptake but blocks full activation in L929 fibroblast cells, and inhibits uptake in HCLE cells. Life Sciences 102:2, pages 105-110.
Crossref
Ji Ma, Wenchao Liu, Hang Guo, Shaoqing Li, Wei Cao, Xilin Du, Shixiong Lei, Wugang Hou, Lize Xiong, Libo Yao, Nanlin Li & Yan Li. (2014) N-myc downstream-regulated gene 2 expression is associated with glucose transport and correlated with prognosis in breast carcinoma. Breast Cancer Research 16:2.
Crossref
Kui Song, Min Li, Xiao-Jun Xu, Li Xuan, Gui-Nian Huang, Xiao-Ling Song & Qi-Fa Liu. (2014) HIF-1α and GLUT1 Gene Expression is Associated with Chemoresistance of Acute Myeloid Leukemia. Asian Pacific Journal of Cancer Prevention 15:4, pages 1823-1829.
Crossref
J Tang, Y Li, K Lyon, J Camps, S Dalton, T Ried & S Zhao. (2013) Cancer driver–passenger distinction via sporadic human and dog cancer comparison: a proof-of-principle study with colorectal cancer. Oncogene 33:7, pages 814-822.
Crossref
Dandan Zhang, Yan Wang, Lina Dong, Yangang Huang, Jing Yuan, Wei Ben, Yang Yang, Ning Ning, Meisong Lu & Yongmei Guan. (2013) Therapeutic role of EF24 targeting glucose transporter 1-mediated metabolism and metastasis in ovarian cancer cells. Cancer Science 104:12, pages 1690-1696.
Crossref
Tiziano Tuccinardi, Carlotta Granchi, Jessica Iegre, Ilaria Paterni, Simone Bertini, Marco Macchia, Adriano Martinelli, Yanrong Qian, Xiaozhuo Chen & Filippo Minutolo. (2013) Oxime-based inhibitors of glucose transporter 1 displaying antiproliferative effects in cancer cells. Bioorganic & Medicinal Chemistry Letters 23:24, pages 6923-6927.
Crossref
J.-H. Lai, H.-J. Jan, L.-W. Liu, C.-C. Lee, S.-G. Wang, D.-Y. Hueng, Y.-Y. Cheng, H.-M. Lee & H.-I. Ma. (2013) Nodal regulates energy metabolism in glioma cells by inducing expression of hypoxia-inducible factor 1 . Neuro-Oncology 15:10, pages 1330-1341.
Crossref
Pablo Moreno-Acosta, Schyrly Carrillo, Oscar Gamboa, Yineth Acosta, Joseph Balart-Serra, Nicolas Magne, Mario Alexander Melo-Uribe & Alfredo Ernesto Romero-Rojas. (2013) Expresión de marcadores hipóxicos y glucolíticos CAIX, GLUT-1, HKII y su relación con la respuesta temprana al tratamiento en carcinoma escamocelular de cuello uterino. Progresos de Obstetricia y Ginecología 56:8, pages 404-413.
Crossref
Mathias Rask-Andersen, Surendar Masuram, Robert Fredriksson & Helgi B. Schiöth. (2013) Solute carriers as drug targets: Current use, clinical trials and prospective. Molecular Aspects of Medicine 34:2-3, pages 702-710.
Crossref
S. Costantini, G. Di Bernardo, M. Cammarota, G. Castello & G. Colonna. (2013) Gene expression signature of human HepG2 cell line. Gene 518:2, pages 335-345.
Crossref
Leszek Szablewski. (2013) Expression of glucose transporters in cancers. Biochimica et Biophysica Acta (BBA) - Reviews on Cancer 1835:2, pages 164-169.
Crossref
Nieng Yan. (2013) Structural advances for the major facilitator superfamily (MFS) transporters. Trends in Biochemical Sciences 38:3, pages 151-159.
Crossref
David P. Kuipers, Jared P. Scripture, Stephen M. Gunnink, Matthew J. Salie, Mark P. Schotanus, John L. Ubels & Larry L. Louters. (2013) Differential regulation of GLUT1 activity in human corneal limbal epithelial cells and fibroblasts. Biochimie 95:2, pages 258-263.
Crossref
Pramila Ramani, Alison Headford & Margaret T May. (2013) GLUT1 protein expression correlates with unfavourable histologic category and high risk in patients with neuroblastic tumours. Virchows Archiv 462:2, pages 203-209.
Crossref
Y-C Shen, D-L Ou, C Hsu, K-L Lin, C-Y Chang, C-Y Lin, S-H Liu & A-L Cheng. (2012) Activating oxidative phosphorylation by a pyruvate dehydrogenase kinase inhibitor overcomes sorafenib resistance of hepatocellular carcinoma. British Journal of Cancer 108:1, pages 72-81.
Crossref
Jin-Qiang Chen & Jose Russo. (2012) Dysregulation of glucose transport, glycolysis, TCA cycle and glutaminolysis by oncogenes and tumor suppressors in cancer cells. Biochimica et Biophysica Acta (BBA) - Reviews on Cancer 1826:2, pages 370-384.
Crossref
Kehinde Adekola, Steven T. Rosen & Mala Shanmugam. (2012) Glucose transporters in cancer metabolism. Current Opinion in Oncology 24:6, pages 650-654.
Crossref
Linfeng Sun, Xin Zeng, Chuangye Yan, Xiuyun Sun, Xinqi Gong, Yu Rao & Nieng Yan. (2012) Crystal structure of a bacterial homologue of glucose transporters GLUT1–4. Nature 490:7420, pages 361-366.
Crossref
Dinesh Rakheja, Shama Khokhar, Midori Mitui & Nicholas G. Cost. (2014) Immunohistochemical Expression of GLUT1 and its Correlation with Unfavorable Histology and TP53 Codon 72 Polymorphism in Wilms Tumors . Pediatric and Developmental Pathology 15:4, pages 286-292.
Crossref
Florian GrabellusKarl WormKurt Werner SchmidSien-Yi Sheu. (2012) The BRAF V600E Mutation in Papillary Thyroid Carcinoma Is Associated with Glucose Transporter 1 Overexpression . Thyroid 22:4, pages 377-382.
Crossref
Lars P. Bechmann, Rebekka A. Hannivoort, Guido Gerken, Gökhan S. Hotamisligil, Michael Trauner & Ali Canbay. (2012) The interaction of hepatic lipid and glucose metabolism in liver diseases. Journal of Hepatology 56:4, pages 952-964.
Crossref
Jim Jinn-Chyuan Sheu, Bin Guan, Fuu-Jen Tsai, Erin Yi-Ting Hsiao, Chih-Mei Chen, Raquel Seruca, Tian-Li Wang & Ie-Ming Shih. (2012) Mutant BRAF Induces DNA Strand Breaks, Activates DNA Damage Response Pathway, and Up-Regulates Glucose Transporter-1 in Nontransformed Epithelial Cells. The American Journal of Pathology 180:3, pages 1179-1188.
Crossref
Langho Lee, Kai Wang, Gang Li, Zhi Xie, Yuli Wang, Jiangchun Xu, Shaoxian Sun, David Pocalyko, Jong Bhak, Chulhong Kim, Kee-Ho Lee, Ye Jin Jang, Young Il Yeom, Hyang-Sook Yoo & Seungwoo Hwang. (2011) Liverome: a curated database of liver cancer-related gene signatures with self-contained context information. BMC Genomics 12:S3.
Crossref
Takeo Nakanishi & Ikumi Tamai. (2011) Solute Carrier Transporters as Targets for Drug Delivery and Pharmacological Intervention for Chemotherapy. Journal of Pharmaceutical Sciences 100:9, pages 3731-3750.
Crossref
Kátia C Carvalho, Isabela W Cunha, Rafael M Rocha, Fernanda R Ayala, Mariana M Cajaíba, Maria D Begnami, Rafael S Vilela, Geise R Paiva, Rodrigo G Andrade & Fernando A Soares. (2011) GLUT1 expression in malignant tumors and its use as an immunodiagnostic marker. Clinics 66:6, pages 965-972.
Crossref
Georgi Kirovski, Axel P. Stevens, Barbara Czech, Katja Dettmer, Thomas S. Weiss, Peter Wild, Arndt Hartmann, Anja K. Bosserhoff, Peter J. Oefner & Claus Hellerbrand. (2011) Down-Regulation of Methylthioadenosine Phosphorylase (MTAP) Induces Progression of Hepatocellular Carcinoma via Accumulation of 5′-Deoxy-5′-Methylthioadenosine (MTA). The American Journal of Pathology 178:3, pages 1145-1152.
Crossref
Tian-Qi Liu, Jun Fan, Lin Zhou & Shu-Sen Zheng. (2011) Effects of suppressing glucose transporter-1 by an antisense oligodeoxynucleotide on the growth of human hepatocellular carcinoma cells. Hepatobiliary & Pancreatic Diseases International 10:1, pages 72-77.
Crossref
Min Zhao, YanMing Chen, DaCheng Qu & Hong Qu. (2011) TSdb: A database of transporter substrates linking metabolic pathways and transporter systems on a genome scale via their shared substrates. Science China Life Sciences 54:1, pages 60-64.
Crossref
X-H Wu, Y-F Lu, X-D Hu, J-Y Mao, X-X Ji, H-T Yao & S-H Zhou. (2010) Expression of Hypoxia Inducible Factor-1α and Its Significance in Laryngeal Carcinoma. Journal of International Medical Research 38:6, pages 2040-2046.
Crossref
X-M Luo, S-H Zhou & J Fan. (2010) Glucose Transporter-1 as a New Therapeutic Target in Laryngeal Carcinoma. Journal of International Medical Research 38:6, pages 1885-1892.
Crossref

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.