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Dickkopf-1 as a potential therapeutic target in Paget's disease of bone

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Pages 221-230 | Published online: 08 Jan 2010

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Laëtitia Michou & Jacques P Brown. (2011) Emerging strategies and therapies for treatment of Paget’s disease of bone. Drug Design, Development and Therapy 5, pages 225-239.
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Articles from other publishers (13)

Zheng Zhao, Gang Wang, Yanyan Wang, Jinshui Yang, Yiwen Wang, Jian Zhu & Feng Huang. (2018) Correlation between magnetic resonance imaging (MRI) findings and the new bone formation factor Dkk-1 in patients with spondyloarthritis. Clinical Rheumatology 38:2, pages 465-475.
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Harshika Awasthi, Dayanandan Mani, Divya Singh & Atul Gupta. (2018) The underlying pathophysiology and therapeutic approaches for osteoporosis. Medicinal Research Reviews 38:6, pages 2024-2057.
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Xiaoqing Zhu, Yinghua Zhao, Yuxue Jiang, Tianxue Qin, Jintong Chen, Xiao Chu, Qing Yi, Sujun Gao & Siqing Wang. (2017) Dectin-1 signaling inhibits osteoclastogenesis via IL-33-induced inhibition of NFATc1. Oncotarget 8:32, pages 53366-53374.
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Seth D. Goldstein, Matteo Trucco, Wendy Bautista Guzman, Masanori Hayashi & David M. Loeb. (2016) A monoclonal antibody against the Wnt signaling inhibitor dickkopf-1 inhibits osteosarcoma metastasis in a preclinical model. Oncotarget 7:16, pages 21114-21123.
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Xingjing Wu, Yongtao Zhang, Xiong Guo, Hongguang Xu, Zhujun Xu, Dapeng Duan & Kunzheng Wang. (2015) Identification of differentially expressed microRNAs involved in non-traumatic osteonecrosis through microRNA expression profiling. Gene 565:1, pages 22-29.
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Mariejka Beauregard, Edith Gagnon, Sabrina Guay-Bélanger, Ethel S. Siris, Jean Morissette, Jacques P. Brown & Laëtitia Michou. (2013) Genetic Association Study of Dickkopf-1 and Sclerostin Genes with Paget Disease of Bone. Calcified Tissue International 93:5, pages 405-412.
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Cheng-gui Miao, Ying-ying Yang, Xu He, Xiao-feng Li, Cheng Huang, Yan Huang, Lei Zhang, Xiong-Wen Lv, Yong Jin & Jun Li. (2013) Wnt signaling pathway in rheumatoid arthritis, with special emphasis on the different roles in synovial inflammation and bone remodeling. Cellular Signalling 25:10, pages 2069-2078.
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Stuart H. Ralston & Rob Layfield. (2012) Pathogenesis of Paget Disease of Bone. Calcified Tissue International 91:2, pages 97-113.
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Gayathri Subramanian, Harold V. Cohen & Samuel Y.P. Quek. (2011) A model for the pathogenesis of bisphosphonate-associated osteonecrosis of the jaw and teriparatide's potential role in its resolution. Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontology 112:6, pages 744-753.
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Mitsuru Haniu, Tom Horan, Chris Spahr, John Hui, Wei Fan, Ching Chen, William G. Richards & Hsieng S. Lu. (2011) Human Dickkopf-1 (huDKK1) protein: Characterization of glycosylation and determination of disulfide linkages in the two cysteine-rich domains. Protein Science 20:11, pages 1802-1813.
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Helmut Glantschnig, Kevin Scott, Richard Hampton, Nan Wei, Paul McCracken, Pascale Nantermet, Jing Z. Zhao, Salvatore Vitelli, Lingyi Huang, Peter Haytko, Ping Lu, John E. Fisher, Punam Sandhu, Jacquelynn Cook, Donald Williams, William Strohl, Osvaldo Flores, Donald Kimmel, Fubao Wang & Zhiqiang An. (2011) A Rate-Limiting Role for Dickkopf-1 in Bone Formation and the Remediation of Bone Loss in Mouse and Primate Models of Postmenopausal Osteoporosis by an Experimental Therapeutic Antibody. Journal of Pharmacology and Experimental Therapeutics 338:2, pages 568-578.
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Alexandra Filipovich, Iris Gehrke, Simon J. Poll-Wolbeck & Karl-Anton Kreuzer. (2011) Physiological inhibitors of Wnt signaling. European Journal of Haematology 86:6, pages 453-465.
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Helmut Glantschnig, Richard A. Hampton, Ping Lu, Jing Z. Zhao, Salvatore Vitelli, Lingyi Huang, Peter Haytko, Tara Cusick, Cheryl Ireland, Stephen W. Jarantow, Robin Ernst, Nan Wei, Pascale Nantermet, Kevin R. Scott, John E. Fisher, Fabio Talamo, Laura Orsatti, Alfred A. Reszka, Punam Sandhu, Donald Kimmel, Osvaldo Flores, William Strohl, Zhiqiang An & Fubao Wang. (2010) Generation and Selection of Novel Fully Human Monoclonal Antibodies That Neutralize Dickkopf-1 (DKK1) Inhibitory Function in Vitro and Increase Bone Mass in Vivo. Journal of Biological Chemistry 285:51, pages 40135-40147.
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