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Review

Novel targets for myeloma bone disease

, MD PhD
Pages 1377-1387 | Published online: 14 Oct 2008

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (3)

Laëtitia Michou & Jacques P Brown. (2011) Emerging strategies and therapies for treatment of Paget’s disease of bone. Drug Design, Development and Therapy 5, pages 225-239.
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Øystein Bruserud & Håkon Reikvam. (2010) Therapeutic targeting of NF-κB in myelodysplastic syndromes and acute myeloid leukaemia – the biological heterogeneity. Expert Opinion on Therapeutic Targets 14:11, pages 1139-1142.
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Pasquale Niscola, Laura Scaramucci, Claudio Romani, Marco Giovannini, Andrea Tendas, Gregorio Brunetti, Claudio Cartoni, Roberto Palumbo, Gisella Vischini, Agostina Siniscalchi, Paolo de Fabritiis & Tommaso Caravita. (2010) Pain management in multiple myeloma. Expert Review of Anticancer Therapy 10:3, pages 415-425.
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Nikolaos Kanellias, Ioannis Ntanasis-Stathopoulos, Maria Gavriatopoulou, Vassilis Koutoulidis, Despina Fotiou, Magdalini Migkou, Evangelos Eleutherakis-Papaiakovou, Panagiotis Malandrakis, Tina Bagratuni, Stylianos Mavropoulos-Papoudas, Maria Roussou, Efstathios Kastritis, Lia A. Moulopoulos, Meletios A. Dimopoulos & Evangelos Terpos. (2022) Newly Diagnosed Multiple Myeloma Patients with Skeletal-Related Events and Abnormal MRI Pattern Have Poor Survival Outcomes: A Prospective Study on 370 Patients. Journal of Clinical Medicine 11:11, pages 3088.
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HendS El Shewaikh, DinaA El-Shahat, AtefM Taha & NagwaM B -E Abdo. (2022) Serum B-cell maturation antigen level in multiple myeloma. Tanta Medical Journal 50:4, pages 333.
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Shiva Kumar Reddy Mukkamalla & Dhatri Malipeddi. (2021) Myeloma Bone Disease: A Comprehensive Review. International Journal of Molecular Sciences 22:12, pages 6208.
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Krystal Bergin, Cameron Wellard, Elizabeth Moore, Zoe McQuilten, Hilary Blacklock, Simon J. Harrison, P. Joy Ho, Tracy King, Hang Quach, Peter Mollee, Patricia Walker, Erica Wood & Andrew Spencer. (2021) The Myeloma Landscape in Australia and New Zealand: The First 8 Years of the Myeloma and Related Diseases Registry (MRDR). Clinical Lymphoma Myeloma and Leukemia 21:6, pages e510-e520.
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Aaron M. Muscarella, Sergio Aguirre, Xiaoxin Hao, Sarah M. Waldvogel & Xiang H.-F. Zhang. (2021) Exploiting bone niches: progression of disseminated tumor cells to metastasis. Journal of Clinical Investigation 131:6.
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Léa Lemaitre, Laura Do Souto Ferreira, Marie-Véronique Joubert, Hervé Avet-Loiseau, Ludovic Martinet, Jill Corre & Bettina Couderc. (2020) Imprinting of Mesenchymal Stromal Cell Transcriptome Persists even after Treatment in Patients with Multiple Myeloma. International Journal of Molecular Sciences 21:11, pages 3854.
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Yi Qian, Debajyoti Bhowmik, Nandita Kachru, Rohini K Hernandez, Paul Cheng & Alexander Liede. (2017) Utilization of agents to prevent skeletal-related events among patients with multiple myeloma: analysis of real-world data. Supportive Care in Cancer 26:3, pages 807-812.
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Evangelos Terpos & Nikolaos Kanellias. 2018. Personalized Therapy for Multiple Myeloma. Personalized Therapy for Multiple Myeloma 131 167 .
Evangelos Terpos, Nikolaos Kanellias & Noopur Raje. 2018. Multiple Myeloma and Other Plasma Cell Neoplasms. Multiple Myeloma and Other Plasma Cell Neoplasms 111 140 .
Faryal Mirza & Ernesto Canalis. (2015) MANAGEMENT OF ENDOCRINE DISEASE: Secondary osteoporosis: pathophysiology and management. European Journal of Endocrinology 173:3, pages R131-R151.
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Katia Beider, Hanna Bitner, Merav Leiba, Odit Gutwein, Maya Koren-Michowitz, Olga Ostrovsky, Michal Abraham, Hanna Wald, Eithan Galun, Amnon Peled & Arnon Nagler. (2014) Multiple myeloma cells recruit tumor-supportive macrophages through the CXCR4/CXCL12 axis and promote their polarization toward the M2 phenotype. Oncotarget 5:22, pages 11283-11296.
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A Ray, Z Tian, D S Das, R L Coffman, P Richardson, D Chauhan & K C Anderson. (2014) A novel TLR-9 agonist C792 inhibits plasmacytoid dendritic cell-induced myeloma cell growth and enhance cytotoxicity of bortezomib. Leukemia 28:8, pages 1716-1724.
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Abdul HameedJennifer J. BradyPaul DowlingMartin ClynesPeter O'Gorman. (2014) Bone Disease in Multiple Myeloma: Pathophysiology and Management. Cancer Growth and Metastasis 7, pages CGM.S16817.
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Huiling Cao, Ke Zhu, Lugui Qiu, Shuai Li, Hanjie Niu, Mu Hao, Shengyong Yang, Zhongfang Zhao, Yumei Lai, Judith L. Anderson, Jie Fan, Hee-Jeong Im, Di Chen, G. David Roodman & Guozhi Xiao. (2013) Critical Role of AKT Protein in Myeloma-induced Osteoclast Formation and Osteolysis. Journal of Biological Chemistry 288:42, pages 30399-30410.
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Evangelos TerposGareth MorganMeletios A. DimopoulosMatthew T. DrakeSuzanne LentzschNoopur RajeOrhan SezerRamón García-SanzKazuyuki ShimizuIngemar TuressonTony ReimanArtur JurczyszynGiampaolo MerliniAndrew SpencerXavier LeleuMichele CavoNikhil MunshiS. Vincent RajkumarBrian G.M. DurieG. David Roodman. (2013) International Myeloma Working Group Recommendations for the Treatment of Multiple Myeloma–Related Bone Disease. Journal of Clinical Oncology 31:18, pages 2347-2357.
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Jin He, Zhiqiang Liu, Yuhuan Zheng, Jianfei Qian, Haiyan Li, Yong Lu, Jingda Xu, Bangxing Hong, Mingjun Zhang, Pei Lin, Zhen Cai, Robert Z. Orlowski, Larry W. Kwak, Qing Yi & Jing Yang. (2012) p38 MAPK in Myeloma Cells Regulates Osteoclast and Osteoblast Activity and Induces Bone Destruction. Cancer Research 72:24, pages 6393-6402.
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Judith M. Runnels, Alicia L. Carlson, Costas Pitsillides, Brian Thompson, Juwell Wu, Joel A. Spencer, John M. J. Kohler, AbdelKareem Azab, Anne-Sophie Moreau, Scott J. Rodig, Andrew L. Kung, Kenneth C. Anderson, Irene M. Ghobrial & Charles P. Lin. (2011) Optical techniques for tracking multiple myeloma engraftment, growth, and response to therapy. Journal of Biomedical Optics 16:1, pages 011006.
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Monica De Matteo, Anna Elisabetta Brunetti, Eugenio Maiorano, Paola Cafforio, Franco Dammacco & Franco Silvestris. (2010) Constitutive down-regulation of Osterix in osteoblasts from myeloma patients: In vitro effect of Bortezomib and Lenalidomide. Leukemia Research 34:2, pages 243-249.
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Monique A. Hartley-Brown, Daniel M. Sullivan & Rachid Baz. (2010) State-of-the-Art Management of Complications of Myeloma and Its Treatment. Advances in Hematology 2010, pages 1-8.
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Shaoying Li & Gene P. Siegal. (2010) Small Cell Tumors of Bone. Advances in Anatomic Pathology 17:1, pages 1-11.
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William C. Dougall, Michelle Chaisson-Blake, Howard Yeh & Susie Jun. 2010. Myeloma Bone Disease. Myeloma Bone Disease 169 181 .
Christian Jakob, Andrea Goerke, Evangelos Terpos, Jan Sterz, Ulrike Heider, Dagmar Kühnhardt, Susanne Ziefle, Lorenz Kleeberg, Maren Mieth, Ivana von Metzler, Christian Müller & Orhan Sezer. (2009) Serum Levels of Total-RANKL in Multiple Myeloma. Clinical Lymphoma and Myeloma 9:6, pages 430-435.
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Dharminder Chauhan, Ajita V. Singh, Mohan Brahmandam, Ruben Carrasco, Madhavi Bandi, Teru Hideshima, Giada Bianchi, Klaus Podar, Yu-Tzu Tai, Constantine Mitsiades, Noopur Raje, David L. Jaye, Shaji K. Kumar, Paul Richardson, Nikhil Munshi & Kenneth C. Anderson. (2009) Functional Interaction of Plasmacytoid Dendritic Cells with Multiple Myeloma Cells: A Therapeutic Target. Cancer Cell 16:4, pages 309-323.
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