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Expert Opinion on Therapeutic Targets Volume 12, 2008 - Issue 4
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Review

Cysteinyl leukotriene receptor CysLT1 as a novel therapeutic target for allergic rhinitis treatment

Hideaki Shirasaki Assistant Professor Sapporo Medical University, Department of Otolaryngology, S-1 W-16, Chuo-ku, Sapporo, 060-8543, Japan +81 11 611 2111; +81 11 615 5405; [email protected]
, MD, PhD
Pages 415-423 | Published online: 18 Mar 2008

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Tomoko Hommura, Katsuaki Dan, Sho Kanzaki, Kenji Watanabe & Kaoru Ogawa. (2019) Evaluation of the therapeutic potential and underlying mechanisms of synephrine, a component of Kampo medicine, against allergic rhinitis. Cogent Biology 5:1.
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Smita Agarwal, Gorla Venkateswara Reddy & Pallu Reddanna. (2009) Eicosanoids in inflammation and cancer: the role of COX-2. Expert Review of Clinical Immunology 5:2, pages 145-165.
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Articles from other publishers (12)

Na Wang, Xinheng He, Jing Zhao, Hualiang Jiang, Xi Cheng, Yu Xia, H. Eric Xu & Yuanzheng He. (2022) Structural basis of leukotriene B4 receptor 1 activation. Nature Communications 13:1.
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Xiaojun Hu, Junjie Mao, Bin Zhou, Huitao Zhang, Bing Li, Pengfei Pang & Hong Shan. (2019) Generation and phenotype analysis of CysLTR1 L118F mutant mice. Journal of Cellular Biochemistry 121:3, pages 2372-2384.
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Hideaki Shirasaki, Etsuko Kanaizumi & Tetsuo Himi. (2017) Leukotriene D 4 induces chemotaxis in human eosinophilc cell line, EoL-1 cells via CysLT1 receptor activation. Heliyon 3:11, pages e00464.
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Hideaki Shirasaki, Etsuko Kanaizumi & Tetsuo Himi. (2017) Expression and localization of GPR99 in human nasal mucosa. Auris Nasus Larynx 44:2, pages 162-167.
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Yusuke Okuma, Yoshitaka Okamoto, Syuji Yonekura, Tomohisa Iinuma, Toshioki Sakurai, Sawako Hamasaki, Yuji Ohki, Heizaburo Yamamoto & Daiju Sakurai. (2016) Persistent nasal symptoms and mediator release after continuous pollen exposure in an environmental challenge chamber. Annals of Allergy, Asthma & Immunology 117:2, pages 150-157.
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Hideaki Shirasaki, Etsuko Kanaizumi, Nobuhiko Seki & Tetsuo Himi. (2015) Leukotriene E4 induces MUC5AC release from human airway epithelial NCI-H292 cells. Allergology International 64:2, pages 169-174.
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Hideaki Shirasaki, Etsuko Kanaizumi, Nobuhiko Seki, Manabu Fujita, Megumi Kikuchi & Tetsuo Himi. (2013) Localization and Up-Regulation of Cysteinyl Leukotriene-2 Receptor in Human Allergic Nasal Mucosa. Allergology International 62:2, pages 223-228.
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CHERYL A. GRICE, ANNE M. FOURIE & ALICE LEE-DUTRA. 2012. Anti-Inflammatory Drug Discovery. Anti-Inflammatory Drug Discovery 58 103 .
Liefeng Wang, Changsheng Du, Jie Lv, Wei Wei, Ye Cui & Xin Xie. (2011) Antiasthmatic Drugs Targeting the Cysteinyl Leukotriene Receptor 1 Alleviate Central Nervous System Inflammatory Cell Infiltration and Pathogenesis of Experimental Autoimmune Encephalomyelitis. The Journal of Immunology 187:5, pages 2336-2345.
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Ilaria Bettinelli, Davide Graziani, Cristina Marconi, Alessandro Pedretti & Giulio Vistoli. (2011) The Approach of Conformational Chimeras to Model the Role of Proline-Containing Helices on GPCR Mobility: the Fertile Case of Cys-LTR1. ChemMedChem 6:7, pages 1217-1227.
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Rui Zhao, Wen-Zhen Shi, Yong-Mei Zhang, San-Hua Fang & Er-Qing Wei. (2011) Montelukast, a cysteinyl leukotriene receptor-1 antagonist, attenuates chronic brain injury after focal cerebral ischaemia in mice and rats. Journal of Pharmacy and Pharmacology 63:4, pages 550-557.
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. (2011) . Nihon Bika Gakkai Kaishi (Japanese Journal of Rhinology) 50:1, pages 108-109.
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