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Targeting aneuploid cancer cells

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Pages 595-608 | Published online: 12 Feb 2011

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Natalay Kouprina, Mikhail Liskovykh, Nikolai Petrov & Vladimir Larionov. (2020) Human artificial chromosome (HAC) for measuring chromosome instability (CIN) and identification of genes required for proper chromosome transmission. Experimental Cell Research 387:2, pages 111805.
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Mikhail Liskovykh, Nikolay V. Goncharov, Nikolai Petrov, Vasilisa Aksenova, Gianluca Pegoraro, Laurent L. Ozbun, William C. Reinhold, Sudhir Varma, Mary Dasso, Vadim Kumeiko, Hiroshi Masumoto, William C. Earnshaw, Vladimir Larionov & Natalay Kouprina. (2019) A novel assay to screen siRNA libraries identifies protein kinases required for chromosome transmission. Genome Research 29:10, pages 1719-1732.
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Natalay Kouprina, Yves Pommier & Vladimir Larionov. (2018) Novel screen for anti-cancer drugs that elevate chromosome instability (CIN) using human artificial chromosome (HAC). Oncotarget 9:96, pages 36833-36835.
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Hee-Sheung Lee, Mar Carmena, Mikhail Liskovykh, Emma Peat, Jung-Hyun Kim, Mitsuo Oshimura, Hiroshi Masumoto, Marie-Paule Teulade-Fichou, Yves Pommier, William C. Earnshaw, Vladimir Larionov & Natalay Kouprina. (2018) Systematic Analysis of Compounds Specifically Targeting Telomeres and Telomerase for Clinical Implications in Cancer Therapy. Cancer Research 78:21, pages 6282-6296.
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Natalay Kouprina, Nikolai Petrov, Oscar Molina, Mikhail Liskovykh, Elisa Pesenti, Jun-ichirou Ohzeki, Hiroshi Masumoto, William C. Earnshaw & Vladimir Larionov. (2018) Human Artificial Chromosome with Regulated Centromere: A Tool for Genome and Cancer Studies. ACS Synthetic Biology 7:9, pages 1974-1989.
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Nicholas C. O. Lee, Jung-Hyun Kim, Nikolai S. Petrov, Hee-Sheung Lee, Hiroshi Masumoto, William C. Earnshaw, Vladimir Larionov & Natalay Kouprina. (2017) Method to Assemble Genomic DNA Fragments or Genes on Human Artificial Chromosome with Regulated Kinetochore Using a Multi-Integrase System. ACS Synthetic Biology 7:1, pages 63-74.
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Xiu‐Qing Li. 2017. Somatic Genome Variation in Animals, Plants, and Microorganisms. Somatic Genome Variation in Animals, Plants, and Microorganisms 377 403 .
Xiu‐Qing Li, Benoit Bizimungu, Guodong Zhang & Huaijun Si. 2017. Somatic Genome Variation in Animals, Plants, and Microorganisms. Somatic Genome Variation in Animals, Plants, and Microorganisms 309 335 .
Jung-Hyun Kim, Hee-Sheung Lee, Nicholas C. O. Lee, Nikolay V. Goncharov, Vadim Kumeiko, Hiroshi Masumoto, William C. Earnshaw, Natalay Kouprina & Vladimir Larionov. (2016) Development of a novel HAC-based “gain of signal” quantitative assay for measuring chromosome instability (CIN) in cancer cells. Oncotarget 7:12, pages 14841-14856.
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Hee-Sheung Lee, Nicholas C.O. Lee, Natalay Kouprina, Jung-Hyun Kim, Alex Kagansky, Susan Bates, Jane B. Trepel, Yves Pommier, Dan Sackett & Vladimir Larionov. (2016) Effects of Anticancer Drugs on Chromosome Instability and New Clinical Implications for Tumor-Suppressing Therapies. Cancer Research 76:4, pages 902-911.
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Hee-Sheung Lee, Nicholas CO Lee, Brenda R Grimes, Alexander Samoshkin, Artem V Kononenko, Ruchi Bansal, Hiroshi Masumoto, William C Earnshaw, Natalay Kouprina & Vladimir Larionov. (2013) A new assay for measuring chromosome instability (CIN) and identification of drugs that elevate CIN in cancer cells. BMC Cancer 13:1.
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Nataša Todorović-Raković. (2011) Genome-based versus gene-based theory of cancer: Possibleimplications for clinical practice. Journal of Biosciences 36:4, pages 719-724.
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