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SIRT1: new avenues of discovery for disorders of oxidative stress

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Pages 167-178 | Published online: 10 Jan 2012

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Emad H. M. Hassanein, Fayez M. Saleh, Fares E. M. Ali, Eman K. Rashwan, Ahmed M. Atwa & Omnia A. M. Abd El-Ghafar. (2023) Neuroprotective effect of canagliflozin against cisplatin-induced cerebral cortex injury is mediated by regulation of HO-1/PPAR-γ, SIRT1/FOXO-3, JNK/AP-1, TLR4/iNOS, and Ang II/Ang 1–7 signals. Immunopharmacology and Immunotoxicology 45:3, pages 304-316.
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Pengyun Li, Xingmin Wang, Ming Zhao, Rui Song & Ke-seng Zhao. (2015) Polydatin protects hepatocytes against mitochondrial injury in acute severe hemorrhagic shock via SIRT1-SOD2 pathway. Expert Opinion on Therapeutic Targets 19:7, pages 997-1010.
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Kenneth Maiese. (2014) Taking aim at Alzheimer's disease through the mammalian target of rapamycin. Annals of Medicine 46:8, pages 587-596.
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Kenneth Maiese, Zhao Zhong Chong, Yan Chen Shang & Shaohui Wang. (2013) Novel directions for diabetes mellitus drug discovery. Expert Opinion on Drug Discovery 8:1, pages 35-48.
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Kenneth Maiese, Zhao Zhong Chong, Yan Chen Shang & Shaohui Wang. (2012) Targeting disease through novel pathways of apoptosis and autophagy. Expert Opinion on Therapeutic Targets 16:12, pages 1203-1214.
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Yuzi You & Wei Liang. (2023) SIRT1 and SIRT6: The role in aging-related diseases. Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease 1869:7, pages 166815.
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Rafighe Ghiasi, Roya Naderi, Roghayeh Sheervalilou & Mohammad Reza Alipour. (2019) Swimming training by affecting the pancreatic Sirtuin1 ( SIRT1 ) and oxidative stress, improves insulin sensitivity in diabetic male rats . Hormone Molecular Biology and Clinical Investigation 40:3.
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Xiaolei Bi, Qing Ye, Daoyuan Li, Qisheng Peng, Zhe Wang, Xiao Wu, Yun Zhang, Qunye Zhang & Fan Jiang. (2019) Inhibition of nucleolar stress response by Sirt1: A potential mechanism of acetylation‐independent regulation of p53 accumulation. Aging Cell 18:2.
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Shanshan Wang, Qian Luo & Peihong Fan. (2019) Cannabisin F from Hemp (Cannabis sativa) Seed Suppresses Lipopolysaccharide-Induced Inflammatory Responses in BV2 Microglia as SIRT1 Modulator. International Journal of Molecular Sciences 20:3, pages 507.
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Feixue Wang, Yu Cao, Lina Ma, Hui Pei, Wolf Dieter Rausch & Hao Li. (2018) Dysfunction of Cerebrovascular Endothelial Cells: Prelude to Vascular Dementia. Frontiers in Aging Neuroscience 10.
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Yasser Mostafa Hafez, Omnia Safwat El-Deeb & Marwa Mohamed Atef. (2018) The emerging role of the epigenetic enzyme Sirtuin-1 and high mobility group Box 1 in patients with diabetic foot ulceration. Diabetes & Metabolic Syndrome: Clinical Research & Reviews 12:6, pages 1065-1070.
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Yang-Ting Dong, Kun Cao, Long-Chun Tan, Xiao-Ling Wang, Xiao-Lan Qi, Yan Xiao & Zhi-Zhong Guan. (2018) Stimulation of SIRT1 Attenuates the Level of Oxidative Stress in the Brains of APP/PS1 Double Transgenic Mice and in Primary Neurons Exposed to Oligomers of the Amyloid-β Peptide. Journal of Alzheimer's Disease 63:1, pages 283-301.
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Liying Yang, Yingying Zhang, Zhongrui Yan & Feng Tian. (2017) The role of mTOR signaling pathway on cognitive functions in cerebral ischemia-reperfusion. Experimental and Therapeutic Medicine 14:4, pages 2839-2844.
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Xiao-Li Wang, Ting Li, Ji-Hong Li, Shu-Ying Miao & Xian-Zhong Xiao. (2017) The Effects of Resveratrol on Inflammation and Oxidative Stress in a Rat Model of Chronic Obstructive Pulmonary Disease. Molecules 22:9, pages 1529.
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Xun Xia, Bo Qu, Yun-Ming Li, Li-Bin Yang, Ke-Xia Fan, Hui Zheng, Hai-Dong Huang, Jian-Wen Gu, Yong-Qin Kuang & Yuan Ma. (2016) NFAT5 protects astrocytes against oxygen–glucose–serum deprivation/restoration damage via the SIRT1/Nrf2 pathway. Journal of Molecular Neuroscience 61:1, pages 96-104.
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Beata Jablonska, Marcin Gierdalski, Li-Jin Chew, Teresa Hawley, Mackenzie Catron, Arturo Lichauco, Juan Cabrera-Luque, Tracy Yuen, David Rowitch & Vittorio Gallo. (2016) Sirt1 regulates glial progenitor proliferation and regeneration in white matter after neonatal brain injury. Nature Communications 7:1.
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Kenneth Maiese. (2016) Targeting molecules to medicine with mTOR, autophagy and neurodegenerative disorders. British Journal of Clinical Pharmacology 82:5, pages 1245-1266.
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Xiang-Sheng Zhang, Qi Wu, Ling-Yun Wu, Zhen-Nan Ye, Tian-Wei Jiang, Wei Li, Zong Zhuang, Meng-Liang Zhou, Xin Zhang & Chun-Hua Hang. (2016) Sirtuin 1 activation protects against early brain injury after experimental subarachnoid hemorrhage in rats. Cell Death & Disease 7:10, pages e2416-e2416.
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A. P. Lan, J. Chen, Z. F. Chai & Y. Hu. (2016) The neurotoxicity of iron, copper and cobalt in Parkinson’s disease through ROS-mediated mechanisms. BioMetals 29:4, pages 665-678.
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Ivan Curjuric, Medea Imboden, Pierre-Olivier Bridevaux, Margaret W. Gerbase, Margot Haun, Dirk Keidel, Ashish Kumar, Marco Pons, Thierry Rochat, Tamara Schikowski, Christian Schindler, Arnold von Eckardstein, Florian Kronenberg & Nicole M. Probst-Hensch. (2016) Common SIRT1 variants modify the effect of abdominal adipose tissue on aging-related lung function decline. AGE 38:3.
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DENG-FENG YU, SU-JUAN JIANG, ZHI-PENG PAN, WEI-DONG CHENG, WEN-JUN ZHANG, XIAO-KUN YAO, YU-CHENG LI & YONG-ZHI LUN. (2016) Expression and clinical significance of Sirt1 in colorectal cancer. Oncology Letters 11:2, pages 1167-1172.
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Kenneth Maiese. (2016) Novel nervous and multi-system regenerative therapeutic strategies for diabetes mellitus with mTOR. Neural Regeneration Research 11:3, pages 372.
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Lingjing Tan, Xiang Zhang, Zhigang Mei, Jinfeng Wang, Xiaoli Li, Weifeng Huang & Songbai Yang. (2016) Fermented Chinese Formula Shuan-Tong-Ling Protects Brain Microvascular Endothelial Cells against Oxidative Stress Injury. Evidence-Based Complementary and Alternative Medicine 2016, pages 1-13.
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Solaleh Emamgholipour, Arash Hossein-nezhad, Mohammad Ali Sahraian, Fatemeh Askarisadr & Mohammad Ansari. (2016) Evidence for possible role of melatonin in reducing oxidative stress in multiple sclerosis through its effect on SIRT1 and antioxidant enzymes. Life Sciences 145, pages 34-41.
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Kenneth Maiese. 2016. Molecules to Medicine with mTOR. Molecules to Medicine with mTOR 3 22 .
Zhuangzhi Meng, Jianguo Li, Honglin Zhao, Haiying Liu, Guowei Zhang, Lingzhan Wang, He Hu, Di Li, Mingjing Liu, Fulong Bi, Xiaoping Wang, Geng Tian, Qiang Liu & Batu Buren. (2015) Resveratrol relieves ischemia‑induced oxidative stress in the hippocampus by activating SIRT1. Experimental and Therapeutic Medicine.
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Kenneth Maiese. (2015) Novel applications of trophic factors, Wnt and WISP for neuronal repair and regeneration in metabolic disease. Neural Regeneration Research 10:4, pages 518.
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Kenneth Maiese. (2015) New Insights for Oxidative Stress and Diabetes Mellitus. Oxidative Medicine and Cellular Longevity 2015, pages 1-17.
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Kenneth Maiese. (2015) FoxO Proteins in the Nervous System. Analytical Cellular Pathology 2015, pages 1-15.
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HUAN GONG, JING PANG, YIWEN HAN, YANG DAI, DAPENG DAI, JIANPING CAI & TIE-MEI ZHANG. (2014) Age-dependent tissue expression patterns of Sirt1 in senescence-accelerated mice. Molecular Medicine Reports 10:6, pages 3296-3302.
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Marilia Brito Gomes & Carlos Antonio Negrato. (2014) Alpha-lipoic acid as a pleiotropic compound with potential therapeutic use in diabetes and other chronic diseases. Diabetology & Metabolic Syndrome 6:1.
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Sonal A. PatelNikkhil S. VelingkaarRoman V. Kondratov. (2014) Transcriptional Control of Antioxidant Defense by the Circadian Clock. Antioxidants & Redox Signaling 20:18, pages 2997-3006.
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David Castaño, Eduardo Larequi, Idoia Belza, Alma M. Astudillo, Eduardo Martínez-Ansó, Jesús Balsinde, Josepmaria Argemi, Tomás Aragon, María J. Moreno-Aliaga, Jordi Muntane, Jesús Prieto & Matilde Bustos. (2014) Cardiotrophin-1 eliminates hepatic steatosis in obese mice by mechanisms involving AMPK activation. Journal of Hepatology 60:5, pages 1017-1025.
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Qinru Sun, Ning Jia, Weixi Wang, Hui Jin, Jiehua Xu & Haitao Hu. (2014) Activation of SIRT1 by curcumin blocks the neurotoxicity of amyloid-β25–35 in rat cortical neurons. Biochemical and Biophysical Research Communications 448:1, pages 89-94.
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Suowen Xu, Peter Bai, Peter J. Little & Peiqing Liu. (2014) Poly(ADP-ribose) Polymerase 1 (PARP1) in Atherosclerosis: From Molecular Mechanisms to Therapeutic Implications. Medicinal Research Reviews 34:3, pages 644-675.
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Jianguo Li, Li Feng, Yonghua Xing, Yan Wang, Liqing Du, Chang Xu, Jia Cao, Qin Wang, Saijun Fan, Qiang Liu & Feiyue Fan. (2014) Radioprotective and Antioxidant Effect of Resveratrol in Hippocampus by Activating Sirt1. International Journal of Molecular Sciences 15:4, pages 5928-5939.
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Carles Cantó, Anthony A. Sauve & Peter Bai. (2013) Crosstalk between poly(ADP-ribose) polymerase and sirtuin enzymes. Molecular Aspects of Medicine 34:6, pages 1168-1201.
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Kaipeng Huang, Juan Huang, Xi Xie, Shaogui Wang, Cheng Chen, Xiaoyan Shen, Peiqing Liu & Heqing Huang. (2013) Sirt1 resists advanced glycation end products-induced expressions of fibronectin and TGF-β1 by activating the Nrf2/ARE pathway in glomerular mesangial cells. Free Radical Biology and Medicine 65, pages 528-540.
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Zhao Zhong Chong. (2013) Implications of a novel point mutation of SIRT1 in T1DM. Nature Reviews Endocrinology 9:6, pages 323-324.
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Ahlam A. AliJonathan A. CoulterClaire H. OgleMarie M. MigaudDavid G. HirstTracy RobsonHelen O. McCarthy. (2013) The contribution of N2O3 to the cytotoxicity of the nitric oxide donor DETA/NO: an emerging role for S-nitrosylation. Bioscience Reports 33:2.
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Shiying ShaoYan YangGang YuanMuxun ZhangXuefeng Yu. (2013) Signaling Molecules Involved in Lipid-Induced Pancreatic Beta-Cell Dysfunction. DNA and Cell Biology 32:2, pages 41-49.
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Y. Ren, T.Z. Shan, L.N. Zhu, T. Wu, J. Guo & Y.Z. Wang. (2013) Effect of breed on the expression of Sirtuins (Sirt1-7) and antioxidant capacity in porcine brain. Animal 7:12, pages 1994-1998.
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Zhao Zhong Chong, Yan Chen Shang, Shaohui Wang & Kenneth Maiese. (2012) A critical kinase cascade in neurological disorders: PI3K, Akt and mTOR. Future Neurology 7:6, pages 733-748.
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Zhao Zhong Chong, Yan Chen Shang, Shaohui Wang & Kenneth Maiese. (2012) Shedding new light on neurodegenerative diseases through the mammalian target of rapamycin. Progress in Neurobiology 99:2, pages 128-148.
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Kenneth Maiese, Zhao Chong, Shaohui Wang & Yan Shang. (2012) Oxidant Stress and Signal Transduction in the Nervous System with the PI 3-K, Akt, and mTOR Cascade. International Journal of Molecular Sciences 13:12, pages 13830-13866.
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Kenneth Maiese, Zhao Zhong Chong, Yan Chen Shang & Shaohui Wang. (2012) Erythropoietin: New Directions for the Nervous System. International Journal of Molecular Sciences 13:9, pages 11102-11129.
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Dae-Won Kim, Young-Mi Kim, Sung-Don Kang, Young-Min Han & Hyun-Ock Pae. (2012) Effects of Resveratrol and trans-3,5,4'-Trimethoxystilbene on Glutamate-Induced Cytotoxicity, Heme Oxygenase-1, and Sirtuin 1 in HT22 Neuronal Cells. Biomolecules and Therapeutics 20:3, pages 306-312.
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Zhao Chong & Kenneth Maiese. (2012) Mammalian target of rapamycin signaling in diabetic cardiovascular disease. Cardiovascular Diabetology 11:1, pages 45.
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Ji Hee Lim, Eun Nim Kim, Min Young Kim, Sungjin Chung, Seok Joon Shin, Hyung Wook Kim, Chul Woo Yang, Yong-Soo Kim, Yoon Sik Chang, Cheol Whee Park & Bum Soon Choi. (2012) Age-Associated Molecular Changes in the Kidney in Aged Mice. Oxidative Medicine and Cellular Longevity 2012, pages 1-10.
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