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Expert Opinion on Therapeutic Targets Volume 16, 2012 - Issue 8
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Sclerostin: a possible target for the management of cancer-induced bone disease

Maria GkotzamanidouUniversity of Athens School of Medicine, Alexandra General Hospital, Department of Clinical Therapeutics, 80 Vas. Sofias Avenue, 11528, Athens, [email protected]
,
Meletios A DimopoulosUniversity of Athens School of Medicine, Alexandra General Hospital, Department of Clinical Therapeutics, 80 Vas. Sofias Avenue, 11528, Athens, [email protected]
,
Efstathios KastritisUniversity of Athens School of Medicine, Alexandra General Hospital, Department of Clinical Therapeutics, 80 Vas. Sofias Avenue, 11528, Athens, [email protected]
,
Dimitrios ChristoulasUniversity of Athens School of Medicine, Alexandra General Hospital, Department of Clinical Therapeutics, 80 Vas. Sofias Avenue, 11528, Athens, [email protected]
,
Lia A MoulopoulosUniversity of Athens School of Medicine, Alexandra General Hospital, Department of Clinical Therapeutics, 80 Vas. Sofias Avenue, 11528, Athens, [email protected]
&
Evangelos TerposUniversity of Athens School of Medicine, Alexandra General Hospital, Department of Clinical Therapeutics, 80 Vas. Sofias Avenue, 11528, Athens, [email protected]
Pages 761-769 | Published online: 05 Jul 2012

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Ayesha Sohail, Lubna Sherin, Saad I Butt, Sana Javed, Zhiwu Li, Sohail Iqbal & O Anwar Be’g. (2018) Role of key players in paradigm shifts of prostate cancer bone metastasis. Cancer Management and Research 10, pages 1619-1626.
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Maria Gavriatopoulou, Meletios A. Dimopoulos, Efstathios Kastritis & Evangelos Terpos. (2017) Emerging treatment approaches for myeloma-related bone disease. Expert Review of Hematology 10:3, pages 217-228.
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Carmel Jacobs, Demetrios Simos, Christina Addison, Mohammed Ibrahim & Mark Clemons. (2014) Pharmacotherapy of bone metastases in breast cancer patients – an update. Expert Opinion on Pharmacotherapy 15:8, pages 1109-1118.
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Articles from other publishers (26)

Kairui Zhang, Courtney Ogando, Alex Filip, Teng Zhang, Jason A Horton & Pranav Soman. (2022) In vitro model to study confined osteocyte networks exposed to flow-induced mechanical stimuli. Biomedical Materials 17:6, pages 065027.
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Jakub Litak, Wojciech Czyżewski, Michał Szymoniuk, Leon Sakwa, Barbara Pasierb, Joanna Litak, Zofia Hoffman, Piotr Kamieniak & Jacek Roliński. (2022) Biological and Clinical Aspects of Metastatic Spinal Tumors. Cancers 14:19, pages 4599.
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Edith Bonnelye. 2022. Bone Cancer. Bone Cancer 337 355 .
Yonggang Ma, Di Ran, Xueni Shi, Hongyan Zhao & Zongping Liu. (2021) Cadmium toxicity: A role in bone cell function and teeth development. Science of The Total Environment 769, pages 144646.
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Alisson Clemenceau, Laetitia Michou, Caroline Diorio & Francine Durocher. (2020) Breast Cancer and Microcalcifications: An Osteoimmunological Disorder?. International Journal of Molecular Sciences 21:22, pages 8613.
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Paola Maroni & Paola Bendinelli. (2020) Bone, a Secondary Growth Site of Breast and Prostate Carcinomas: Role of Osteocytes. Cancers 12:7, pages 1812.
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Mengying Zhang, Jinlu Dai & Evan T. Keller. 2020. Encyclopedia of Bone Biology. Encyclopedia of Bone Biology 219 224 .
Adil AkkouchSteven EliasonMason E. SweatMiguel Romero-BustillosMin ZhuFang QianBrad A. AmendtLiu Hong. (2019) Enhancement of MicroRNA-200c on Osteogenic Differentiation and Bone Regeneration by Targeting Sox2-Mediated Wnt Signaling and Klf4. Human Gene Therapy 30:11, pages 1405-1418.
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Yuan S. Zhang, Hyunju Shim & Eileen M. Crimmins. 2019. Reference Module in Biomedical Sciences. Reference Module in Biomedical Sciences.
Song Xu, Kim De Veirman, Ann De Becker, Karin Vanderkerken & Ivan Van Riet. (2018) Mesenchymal stem cells in multiple myeloma: a therapeutical tool or target?. Leukemia 32:7, pages 1500-1514.
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Rachelle W. Johnson & Larry J. Suva. (2017) Hallmarks of Bone Metastasis. Calcified Tissue International 102:2, pages 141-151.
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Else Driehuis & Hans Clevers. (2017) WNT signalling events near the cell membrane and their pharmacological targeting for the treatment of cancer. British Journal of Pharmacology 174:24, pages 4547-4563.
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Aline G. Costa, Serge Cremers & John P. Bilezikian. (2017) Sclerostin measurement in human disease: Validity and current limitations. Bone 96, pages 24-28.
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Yusuke Inagaki, Edward S Hookway, Takeshi G Kashima, Mitsuru Munemoto, Yasuhito Tanaka, Andrew Bassim Hassan, Udo Oppermann & Nick A Athanasou. (2016) Sclerostin expression in bone tumours and tumour-like lesions. Histopathology 69:3, pages 470-478.
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Fei Shen, Yun Zhang, Danielle L. Jernigan, Xin Feng, Jie Yan, Fernando U. Garcia, Olimpia Meucci, Joseph M. Salvino & Alessandro Fatatis. (2016) Novel Small-Molecule CX3CR1 Antagonist Impairs Metastatic Seeding and Colonization of Breast Cancer Cells. Molecular Cancer Research 14:6, pages 518-527.
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Isabelle Piec, Christopher Washbourne, Jonathan Tang, Emily Fisher, Julie Greeves, Sarah Jackson & William D. Fraser. (2016) How Accurate is Your Sclerostin Measurement? Comparison Between Three Commercially Available Sclerostin ELISA Kits. Calcified Tissue International 98:6, pages 546-555.
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Issam Makhoul, Corey O. Montgomery, Dana Gaddy & Larry J. Suva. (2015) The best of both worlds — managing the cancer, saving the bone. Nature Reviews Endocrinology 12:1, pages 29-42.
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Julia Dotterweich, Regina Ebert, Sabrina Kraus, Robert J Tower, Franz Jakob & Norbert Schütze. (2014) Mesenchymal stem cell contact promotes CCN1 splicing and transcription in myeloma cells. Cell Communication and Signaling 12:1.
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Jocelyn T. Compton & Francis Y. Lee. (2014) A Review of Osteocyte Function and the Emerging Importance of Sclerostin. Journal of Bone and Joint Surgery 96:19, pages 1659-1668.
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S L Webb & C M Edwards. (2014) Novel therapeutic targets in myeloma bone disease. British Journal of Pharmacology 171:16, pages 3765-3776.
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Evangelos Terpos, Nikolaos Kanellias & Krzysztof Giannopoulos. (2014) Biology and management of myeloma-related bone disease. Acta Haematologica Polonica 45:2, pages 107-121.
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Natasa Kovacic, Peter I. Croucher & Michelle M. McDonald. (2013) Signaling Between Tumor Cells and the Host Bone Marrow Microenvironment. Calcified Tissue International 94:1, pages 125-139.
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Janet E. Brown, Liang Zeng & Caroline Wilson. 2014. Bone Metastases. Bone Metastases 95 124 .
Sandy R. Larson, Xiaotun Zhang, Ruth Dumpit, Ilsa Coleman, Bryce Lakely, Martine Roudier, Celestia S. Higano, Lawrence D. True, Paul H. Lange, Bruce Montgomery, Eva Corey, Peter S. Nelson, Robert L. Vessella & Colm Morrissey. (2013) Characterization of osteoblastic and osteolytic proteins in prostate cancer bone metastases. The Prostate 73:9, pages 932-940.
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Jesús Delgado-Calle, Jana Arozamena, Javier Pérez-López, Alfonso Bolado-Carrancio, Carolina Sañudo, Gloria Agudo, Rosa de la Vega, María A. Alonso, José Carlos Rodríguez-Rey & José A. Riancho. (2013) Role of BMPs in the regulation of sclerostin as revealed by an epigenetic modifier of human bone cells. Molecular and Cellular Endocrinology 369:1-2, pages 27-34.
Crossref
Evangelos Terpos, Efstathios Kastritis & Meletios A. Dimopoulos. (2012) Prevention and Treatment of Myeloma Bone Disease. Current Hematologic Malignancy Reports 7:4, pages 249-257.
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