364
Views
39
CrossRef citations to date
0
Altmetric
Reviews

Targeting α-amino-3-hydroxyl-5-methyl-4-isoxazole-propionate receptors in epilepsy

, , , , MD &

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (5)

Marco Greco, Gaia Varriale, Giangennaro Coppola, Francesca Operto, Alberto Verrotti & Maria Laura Iezzi. (2018) Investigational small molecules in phase II clinical trials for the treatment of epilepsy. Expert Opinion on Investigational Drugs 27:12, pages 971-979.
Read now
Carlo Di Bonaventura, Angelo Labate, Marta Maschio, Stefano Meletti & Emilio Russo. (2017) AMPA receptors and perampanel behind selected epilepsies: current evidence and future perspectives. Expert Opinion on Pharmacotherapy 18:16, pages 1751-1764.
Read now
Andreas Schulze-Bonhage & Mandy Hintz. (2015) Perampanel in the management of partial-onset seizures: a review of safety, efficacy, and patient acceptability. Patient Preference and Adherence 9, pages 1143-1151.
Read now
Caterina Palleria, Antonietta Coppola, Rita Citraro, Luigi Del Gaudio, Salvatore Striano, Giovambattista De Sarro & Emilio Russo. (2015) Perspectives on treatment options for mesial temporal lobe epilepsy with hippocampal sclerosis. Expert Opinion on Pharmacotherapy 16:15, pages 2355-2371.
Read now
Andreas Schulze-Bonhage. (2015) Perampanel for epilepsy with partial-onset seizures: a pharmacokinetic and pharmacodynamic evaluation. Expert Opinion on Drug Metabolism & Toxicology 11:8, pages 1329-1337.
Read now

Articles from other publishers (34)

Alyaa Nasr, Israa Yosuf, Zaki Turki & Ann Abozeid. (2023) LC-MS metabolomics profiling of Salvia aegyptiaca L. and S. lanigera Poir. with the antimicrobial properties of their extracts. BMC Plant Biology 23:1.
Crossref
Laura Bellingacci, Martina Tallarico, Andrea Mancini, Alfredo Megaro, Carmen De Caro, Rita Citraro, Giovambattista De Sarro, Alessandro Tozzi, Massimiliano Di Filippo, Miriam Sciaccaluga, Emilio Russo, Antonio Leo & Cinzia Costa. (2023) Non-competitive AMPA glutamate receptors antagonism by perampanel as a strategy to counteract hippocampal hyper-excitability and cognitive deficits in cerebral amyloidosis. Neuropharmacology 225, pages 109373.
Crossref
Tzu-Hsin Huang, Ming-Chi Lai, Yu-Shiue Chen & Chin-Wei Huang. (2023) The Roles of Glutamate Receptors and Their Antagonists in Status Epilepticus, Refractory Status Epilepticus, and Super-Refractory Status Epilepticus. Biomedicines 11:3, pages 686.
Crossref
Jing Zhao, Cong Wang, Wanbing Sun & Cong Li. (2022) Tailoring Materials for Epilepsy Imaging: From Biomarkers to Imaging Probes. Advanced Materials 34:44.
Crossref
Suresh Kumar Suthar, Narendra Singh Chundawat, Girdhar Pal Singh, José M. Padrón & Yuvraj Kunwar Jhala. (2022) Quinoxaline: A comprehension of current pharmacological advancement in medicinal chemistry. European Journal of Medicinal Chemistry Reports 5, pages 100040.
Crossref
Aman B. Upaganlawar, Nitu L. Wankhede, Mayur B. Kale, Mohit D. Umare, Aayush Sehgal, Sukhbir Singh, Saurabh Bhatia, Ahmed Al-Harrasi, Agnieszka Najda, Renata Nurzyńska-Wierdak, Simona Bungau & Tapan Behl. (2021) Interweaving epilepsy and neurodegeneration: Vitamin E as a treatment approach. Biomedicine & Pharmacotherapy 143, pages 112146.
Crossref
Jia-Hui Sun, Jiang Chen, Fernando Eduardo Ayala Valenzuela, Carolyn Brown, Diane Masser-Frye, Marilyn Jones, Leslie Patron Romero, Berardo Rinaldi, Wenhui Laura Li, Qing-Qing Li, Dan Wu, Benedicte Gerard, Erin Thorpe, Allan Bayat & Yun Stone Shi. (2021) X-linked neonatal-onset epileptic encephalopathy associated with a gain-of-function variant p.R660T in GRIA3. PLOS Genetics 17:6, pages e1009608.
Crossref
Emilio Russo & Rita Citraro. 2021.
Tomoyuki Miyazaki, Waki Nakajima, Mai Hatano, Yusuke Shibata, Yoko Kuroki, Tetsu Arisawa, Asami Serizawa, Akane Sano, Sayaka Kogami, Tomomi Yamanoue, Kimito Kimura, Yushi Hirata, Yuuki Takada, Yoshinobu Ishiwata, Masaki Sonoda, Masaki Tokunaga, Chie Seki, Yuji Nagai, Takafumi Minamimoto, Kazunori Kawamura, Ming-Rong Zhang, Naoki Ikegaya, Masaki Iwasaki, Naoto Kunii, Yuichi Kimura, Fumio Yamashita, Masataka Taguri, Hideaki Tani, Nobuhiro Nagai, Teruki Koizumi, Shinichiro Nakajima, Masaru Mimura, Michisuke Yuzaki, Hiroki Kato, Makoto Higuchi, Hiroyuki Uchida & Takuya Takahashi. (2020) Visualization of AMPA receptors in living human brain with positron emission tomography. Nature Medicine 26:2, pages 281-288.
Crossref
Johannes Mayer, Timo Kirschstein, Tobias Resch, Katrin Porath, Bernd Joachim Krause, Rüdiger Köhling & Falko Lange. (2020) Perampanel attenuates epileptiform phenotype in C6 glioma. Neuroscience Letters 715, pages 134629.
Crossref
Charlotte Stenum-Berg, Maria Musgaard, Sergei Chavez-Abiega, Christine L. Thisted, Lorenzo Barrella, Philip C. Biggin & Anders S. Kristensen. (2019) Mutational Analysis and Modeling of Negative Allosteric Modulator Binding Sites in AMPA Receptors. Molecular Pharmacology 96:6, pages 835-850.
Crossref
Patrizia Ambrogini, Pierangelo Torquato, Desirée Bartolini, Maria Cristina Albertini, Davide Lattanzi, Michael Di Palma, Rita Marinelli, Michele Betti, Andrea Minelli, Riccardo Cuppini & Francesco Galli. (2019) Excitotoxicity, neuroinflammation and oxidant stress as molecular bases of epileptogenesis and epilepsy-derived neurodegeneration: The role of vitamin E. Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease 1865:6, pages 1098-1112.
Crossref
Abdel-Ghany A. El-Helby, Rezk R. A. Ayyad, Khaled El-Adl & Hazem Elkady. (2018) Phthalazine-1,4-dione derivatives as non-competitive AMPA receptor antagonists: design, synthesis, anticonvulsant evaluation, ADMET profile and molecular docking. Molecular Diversity 23:2, pages 283-298.
Crossref
Zhi-Xuan Xia, Zu-Cheng Shen, Shao-Qi Zhang, Ji Wang, Tai-Lei Nie, Qiao Deng, Jian-Guo Chen, Fang Wang & Peng-Fei Wu. (2019) De-palmitoylation by N-(tert-Butyl) hydroxylamine inhibits AMPAR-mediated synaptic transmission via affecting receptor distribution in postsynaptic densities. CNS Neuroscience & Therapeutics 25:2, pages 187-199.
Crossref
Emilio Russo & Rita Citraro. (2018) Pharmacology of epileptogenesis and related comorbidities in the WAG/Rij rat model of genetic absence epilepsy. Journal of Neuroscience Methods 310, pages 54-62.
Crossref
Rita Citraro, Caterina De Sarro, Antonio Leo, Eugenio Donato di Paola, Ernesto Palma, Emilio Russo & Giovambattista De Sarro. (2018) Perampanel chronic treatment does not induce tolerance and decreases tolerance to clobazam in genetically epilepsy prone rats. Epilepsy Research 146, pages 94-102.
Crossref
O. E. Zubareva, A. A. Kovalenko, V. B. Karyakin, S. V. Kalemenev, V. V. Lavrent’eva, L. G. Magazanik & A. V. Zaitsev. (2018) Changes in the Expression of Genes of the Glutamate Transporter and Subunits of the NMDA and AMPA Receptors in the Rat Amygdala in the Lithium–Pilocarpine Model of Epilepsy. Neurochemical Journal 12:3, pages 222-227.
Crossref
Alessandra Morano, Jinane Fattouch, Mariarita Albini, Sara Casciato, Martina Fanella, Luca Manfredi Basili, Alessandro Viganò, Mario Manfredi, Anna Teresa Giallonardo & Carlo Di Bonaventura. (2018) Perampanel as adjunctive therapy in highly refractory epilepsies: Real-world data from an Italian tertiary care epilepsy centre. Journal of the Neurological Sciences 390, pages 67-74.
Crossref
Antonio Leo, Giada Giovannini, Emilio Russo & Stefano Meletti. (2018) The role of AMPA receptors and their antagonists in status epilepticus. Epilepsia 59:6, pages 1098-1108.
Crossref
Xinyuan Yu, Tao Xu, Shu Ou, Jinxian Yuan, Jing Deng, Rong Li, Juan Yang, Xi Liu, Qi Li & Yangmei Chen. (2018) Endophilin A1 mediates seizure activity via regulation of AMPARs in a PTZ-kindled epileptic mouse model. Experimental Neurology 304, pages 41-57.
Crossref
Jinghui Zhang, Nana Qiao, Xiufang Ding & Jiwen Wang. (2018) Disruption of the GluA2/GAPDH complex using TAT-GluA2NT1-3-2 peptide protects against AMPAR-mediated excitotoxicity after epilepsy. NeuroReport 29:5, pages 432-439.
Crossref
Paola De Liso, Romina Moavero, Giangennaro Coppola, Paolo Curatolo, Raffaella Cusmai, Giovambattista De Sarro, Emilio Franzoni, Federico Vigevano & Alberto Verrotti. (2017) Current role of perampanel in pediatric epilepsy. Italian Journal of Pediatrics 43:1.
Crossref
Ewa Szymańska, Paulina Chałupnik, Tommy N. Johansen, Birgitte Nielsen, Ana Maria Cuñado Moral, Darryl S. Pickering, Anna Więckowska & Katarzyna Kieć-Kononowicz. (2017) Aryl- and heteroaryl-substituted phenylalanines as AMPA receptor ligands. Chemical Biology & Drug Design 90:6, pages 1271-1281.
Crossref
Ewa Szymańska, Birgitte Nielsen, Tommy N. Johansen, Ana Maria Cuñado Moral, Darryl S. Pickering, Katarzyna Szczepańska, Anna Mickowska & Katarzyna Kieć-Kononowicz. (2017) Pharmacological characterization and binding modes of novel racemic and optically active phenylalanine-based antagonists of AMPA receptors. European Journal of Medicinal Chemistry 138, pages 874-883.
Crossref
Dmitry V. Amakhin, Sergey L. Malkin, Julia L. Ergina, Kirill A. Kryukov, Ekaterina A. Veniaminova, Olga E. Zubareva & Aleksey V. Zaitsev. (2017) Alterations in Properties of Glutamatergic Transmission in the Temporal Cortex and Hippocampus Following Pilocarpine-Induced Acute Seizures in Wistar Rats. Frontiers in Cellular Neuroscience 11.
Crossref
Milad Espahbodinia, Roberta Ettari, Wei Wen, Andrew Wu, Yu-Chuan Shen, Li Niu, Silvana Grasso & Maria Zappalà. (2017) Development of novel N -3-bromoisoxazolin-5-yl substituted 2,3-benzodiazepines as noncompetitive AMPAR antagonists. Bioorganic & Medicinal Chemistry 25:14, pages 3631-3637.
Crossref
Rita Citraro, Antonio Leo, Valentina Franco, Roberto Marchiselli, Emilio Perucca, Giovambattista De Sarro & Emilio Russo. (2017) Perampanel effects in the WAG/Rij rat model of epileptogenesis, absence epilepsy, and comorbid depressive-like behavior. Epilepsia 58:2, pages 231-238.
Crossref
Song Cai, Chuwen Ling, Jun Lu, Songwei Duan, Yingzhao Wang, Huining Zhu, Ruibang Lin, Liang Chen, Xingchang Pan, Muyi Cai & Huaiyu Gu. (2016) EGAR, A Food Protein-Derived Tetrapeptide, Reduces Seizure Activity in Pentylenetetrazole-Induced Epilepsy Models Through α-Amino-3-Hydroxy-5-Methyl-4-Isoxazole Propionate Receptors. Neurotherapeutics 14:1, pages 212-226.
Crossref
Valentina Franco, Roberto Marchiselli, Cinzia FattoreElena TartaraGiovambattista De SarroEmilio RussoEmilio Perucca. (2016) Development and Validation of an HPLC-UV Assay for the Therapeutic Monitoring of the New Antiepileptic Drug Perampanel in Human Plasma. Therapeutic Drug Monitoring 38:6, pages 744-750.
Crossref
Emilio Russo, Rita Citraro, Andrew Constanti, Antonio Leo, Annika Lüttjohann, Gilles van Luijtelaar & Giovambattista De Sarro. (2016) Upholding WAG/Rij rats as a model of absence epileptogenesis: Hidden mechanisms and a new theory on seizure development. Neuroscience & Biobehavioral Reviews 71, pages 388-408.
Crossref
Sergey L. Malkin, Dmitry V. Amakhin, Ekaterina A. Veniaminova, Kira Kh. Kim, Olga E. Zubareva, Lev G. Magazanik & Aleksey V. Zaitsev. (2016) Changes of AMPA receptor properties in the neocortex and hippocampus following pilocarpine-induced status epilepticus in rats. Neuroscience 327, pages 146-155.
Crossref
Gaetano Zaccara & Dieter Schmidt. (2016) Do traditional anti-seizure drugs have a future? A review of potential anti-seizure drugs in clinical development. Pharmacological Research 104, pages 38-48.
Crossref
Kevin Lee, Lucy Goodman, Chantelle Fourie, Susan Schenk, Beulah Leitch & Johanna M. Montgomery. 2016. Ion Channels as Therapeutic Targets, Part A. Ion Channels as Therapeutic Targets, Part A 203 261 .
Oleg I. Barygin, Margarita S. Komarova, Tatiana B. Tikhonova & Denis B. Tikhonov. (2015) Non-classical mechanism of α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor channel block by fluoxetine. European Journal of Neuroscience 41:7, pages 869-877.
Crossref

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.