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Thymic stromal lymphopoietin: a central regulator of allergic asthma

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Sihui Wen, Shenghao Cheng, Shaobing Xie, Hua Zhang, Zhihai Xie & Weihong Jiang. (2021) Serum YKL-40 Levels Predict Endotypes and Associate with Postoperative Recurrence in Patients with Chronic Rhinosinusitis with Nasal Polyps. Journal of Asthma and Allergy 14, pages 1295-1306.
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Liuzhao Cao, Fen Liu, Yahui Liu, Tian Liu, Jinxiang Wu, Jiping Zhao, Junfei Wang, Shuo Li, Jiawei Xu & Liang Dong. (2018) TSLP promotes asthmatic airway remodeling via p38-STAT3 signaling pathway in human lung fibroblast. Experimental Lung Research 44:6, pages 288-301.
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Amelia Licari, Riccardo Castagnoli, Ilaria Brambilla, Alessia Marseglia, Maria Angela Tosca, Gian Luigi Marseglia & Giorgio Ciprandi. (2018) New approaches for identifying and testing potential new anti-asthma agents. Expert Opinion on Drug Discovery 13:1, pages 51-63.
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Articles from other publishers (45)

Jenny Resiliac, Christopher D. Brooks & Mitchell H. Grayson. (2022) Immunopathology of Differing Viral Infection in Allergic Asthma Disease. Immunology and Allergy Clinics of North America 42:4, pages 715-726.
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Alessandro Vatrella, Angelantonio Maglio, Corrado Pelaia, Luigi Ciampo, Giulia Pelaia & Carolina Vitale. (2022) Eosinophilic inflammation: An Appealing Target for Pharmacologic Treatments in Severe Asthma. Biomedicines 10:9, pages 2181.
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Tracy Augustine, Mohammad Ameen Al-Aghbar, Moza Al-Kowari, Meritxell Espino-Guarch & Nicholas van Panhuys. (2022) Asthma and the Missing Heritability Problem: Necessity for Multiomics Approaches in Determining Accurate Risk Profiles. Frontiers in Immunology 13.
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Weiwei Wang, Hongwei Yu, Yongliang Pan & Shengwen Shao. (2021) Combined Treatment With H1 and H4 Receptor Antagonists Improves Th2 Inflammatory Responses in the Nasal Mucosa of Allergic Rhinitis Rats. American Journal of Rhinology & Allergy 35:6, pages 809-816.
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Matthew A. Tyler, Kent Lam, Michael J. Marino, William C. Yao, Isaac Schmale, Martin J. Citardi & Amber U. Luong. (2021) Revisiting the controversy: The role of fungi in chronic rhinosinusitis. International Forum of Allergy & Rhinology 11:11, pages 1577-1587.
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Ai Jin, Xuemei Tang, Weiqi Zhai, Yuwen Li, Qingzhu Sun, Li Liu, Xiaojun Yang, Hui Ren & Shemin Lu. (2021) TSLP-induced collagen type-I synthesis through STAT3 and PRMT1 is sensitive to calcitriol in human lung fibroblasts. Biochimica et Biophysica Acta (BBA) - Molecular Cell Research 1868:10, pages 119083.
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Richard Haworth, Molly Boyle, Paul Edwards, Reenu Gupta, Rajni Fagg, George Karantabias & Mark Price. (2020) Preclinical Safety Assessment of 2 Inhaled Single-Domain Antibodies in the Cynomolgus Monkey. Toxicologic Pathology 49:2, pages 296-314.
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Wei Wei Wang, Hong Wei Yu, Bo Zhang, Yong Liang Pan & Sheng Wen Shao. (2020) Interleukin-17A up-regulates thymic stromal lymphopoietin production by nasal fibroblasts from patients with allergic rhinitis. European Archives of Oto-Rhino-Laryngology 278:1, pages 127-133.
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Andrew Menzies-Gow, Michael E. Wechsler & Chris E. Brightling. (2020) Unmet need in severe, uncontrolled asthma: can anti-TSLP therapy with tezepelumab provide a valuable new treatment option?. Respiratory Research 21:1.
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Patrycja Nejman-Gryz, Katarzyna Górska, Magdalena Paplińska-Goryca, Małgorzata Proboszcz & Rafał Krenke. (2020) Periostin and Thymic Stromal Lymphopoietin—Potential Crosstalk in Obstructive Airway Diseases. Journal of Clinical Medicine 9:11, pages 3667.
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Thea Magrone, Manrico Magrone & Emilio Jirillo. (2020) Eosinophils, a Jack of All Trades in Immunity: Therapeutic Approaches for Correcting Their Functional Disorders. Endocrine, Metabolic & Immune Disorders - Drug Targets 20:8, pages 1166-1181.
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Kei Sakamoto, Shunji Matsuki, Shin Irie, Naoki Uchida, Nobuya Hayashi, Masato Horiuchi & Song Ren. (2020) A Phase 1, Randomized, Placebo‐Controlled Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Immunogenicity of Subcutaneous Tezepelumab in Healthy Japanese Men. Clinical Pharmacology in Drug Development 9:7, pages 833-840.
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Hoa Le Mai, Thi Van Ha Nguyen, Grégory Bouchaud, Kelly Henrio, Marie‐Aude Cheminant, Antoine Magnan & Sophie Brouard. (2020) Targeting the interleukin‐7 receptor alpha by an anti‐CD127 monoclonal antibody improves allergic airway inflammation in mice. Clinical & Experimental Allergy 50:7, pages 824-834.
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Elissa M. Abrams, Heather E. Hoch, Allan B. Becker & Stanley J. Szefler. 2020. Severe Asthma in Children and Adolescents. Severe Asthma in Children and Adolescents 287 312 .
Su-Li Ma & Lei Zhang. (2019) Elevated serum OX40L is a biomarker for identifying corticosteroid resistance in pediatric asthmatic patients. BMC Pulmonary Medicine 19:1.
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Siji Nian, Jianguang Zhu, Hong Yu, Qi Chen, Yingchun Ye, Xinmei Cao & Qing Yuan. (2019) Development and identification of a fully human single‐chain variable fragment 29 against TSLP. Biotechnology and Applied Biochemistry 66:4, pages 510-516.
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Chenyang Dai, Jiayin Wu, Chen Chen & Xinyi Wu. (2019) Interactions of thymic stromal lymphopoietin with TLR2 and TLR4 regulate anti-fungal innate immunity in Aspergillus fumigatus-induced corneal infection. Experimental Eye Research 182, pages 19-29.
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Ivan I. Balabolkin & I. E. Smirnov. (2019) ALLERGIC BRONCHIAL ASTHMA IN CHILDREN: FEATURES OF THE DEVELOPMENT AND MODERN THERAPY. Russian Pediatric Journal 21:1, pages 38-45.
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Yu‐Chen Huang, Chih‐Ming Weng, Meng‐Jung Lee, Shu‐Min Lin, Chun‐Hua Wang & Han‐Pin Kuo. (2018) Endotypes of severe allergic asthma patients who clinically benefit from anti‐IgE therapy. Clinical & Experimental Allergy 49:1, pages 44-53.
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Jing Wang, Huajie Lv, Zhuang Luo, Shan Mou, Jing Liu, Chang Liu, Shiying Deng, Youfan Jiang, Jiachen Lin, Chengzhou Wu, Xianhong Liu, Jinzhi He & Depeng Jiang. (2018) Plasma YKL-40 and NGAL are useful in distinguishing ACO from asthma and COPD. Respiratory Research 19:1.
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Xiu-Juan Yao, Xiao-Fang Liu & Xiang-Dong Wang. (2018) Potential Role of Interleukin-25/Interleukin-33/Thymic Stromal Lymphopoietin-Fibrocyte Axis in the Pathogenesis of Allergic Airway Diseases. Chinese Medical Journal 131:16, pages 1983-1989.
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Anna E. Ferguson, Vince A. Mukkada & Patricia C. Fulkerson. (2017) Pediatric Eosinophilic Esophagitis Endotypes: Are We Closer to Predicting Treatment Response?. Clinical Reviews in Allergy & Immunology 55:1, pages 43-55.
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S.-Y. Nam, H.-Y. Kim, N.-R. Han, P.-D. Moon, J.-S. Cho, H.-M. Kim & H.-J. Jeong. (2018) Src-type tyrosine kinase p56lck is critical for thymic stromal lymphopoietin-induced allergic rhinitis. Clinical & Experimental Allergy 48:7, pages 875-889.
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Chi Liu, Lin Yuan, Yizhou Zou, Ming Yang, Yu Chen, Xiangping Qu, Huijun Liu, Jianxin Jiang, Yang Xiang & Xiaoqun Qin. (2018) ITGB4 is essential for containing HDM-induced airway inflammation and airway hyperresponsiveness . Journal of Leukocyte Biology 103:5, pages 897-908.
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Yan Li, Wei Wang, Zhe Lv, Yun Li, Yan Chen, Kewu Huang, Chris J. Corrigan & Sun Ying. (2018) Elevated Expression of IL-33 and TSLP in the Airways of Human Asthmatics In Vivo: A Potential Biomarker of Severe Refractory Disease. The Journal of Immunology 200:7, pages 2253-2262.
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Dhuha Al-Sajee, John-Paul Oliveria, Roma Sehmi & Gail M. Gauvreau. (2018) Antialarmins for treatment of asthma. Current Opinion in Pulmonary Medicine 24:1, pages 32-41.
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Cristina T Vicente, Joana A Revez & Manuel A R Ferreira. (2017) Lessons from ten years of genome-wide association studies of asthma. Clinical & Translational Immunology 6:12, pages e165.
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Iñigo Ojanguren, James G. Martin & Catherine Lemiere. (2017) Thymic Stromal Lymphopoietin: A Promising Target in the Treatment of Asthma?. Archivos de Bronconeumología 53:10, pages 545-546.
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Iñigo Ojanguren, James G. Martin & Catherine Lemiere. (2017) Thymic Stromal Lymphopoietin: A Promising Target in the Treatment of Asthma?. Archivos de Bronconeumología (English Edition) 53:10, pages 545-546.
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Joanna Wieczfinska & Rafal Pawliczak. (2017) Thymic stromal lymphopoietin and apocynin alter the expression of airway remodeling factors in human rhinovirus-infected cells. Immunobiology 222:8-9, pages 892-899.
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Amber N. Pepper, Harald Renz, Thomas B. Casale & Holger Garn. (2017) Biologic Therapy and Novel Molecular Targets of Severe Asthma. The Journal of Allergy and Clinical Immunology: In Practice 5:4, pages 909-916.
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Patrick D. Mitchell & Paul M. O’Byrne. (2017) Epithelial-Derived Cytokines in Asthma. Chest 151:6, pages 1338-1344.
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Sara C. Sebag, Olha M. Koval, John D. Paschke, Christopher J. Winters, Omar A. Jaffer, Ryszard Dworski, Fayyaz S. Sutterwala, Mark E. Anderson & Isabella M. Grumbach. (2017) Mitochondrial CaMKII inhibition in airway epithelium protects against allergic asthma. JCI Insight 2:3.
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Andreas R. Koczulla, Claus F. Vogelmeier, Holger Garn & Harald Renz. (2017) New concepts in asthma: clinical phenotypes and pathophysiological mechanisms. Drug Discovery Today 22:2, pages 388-396.
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Patrick D. Mitchell & Paul M. O'Byrne. (2017) Biologics and the lung: TSLP and other epithelial cell-derived cytokines in asthma. Pharmacology & Therapeutics 169, pages 104-112.
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Tatyana Gavrilova, Saritha Kartan, Lauren S. Sherman, Oleta A. Sandiford & Pranela Rameshwar. 2016. The Biology and Therapeutic Application of Mesenchymal Cells. The Biology and Therapeutic Application of Mesenchymal Cells 573 580 .
Rasha Genedy, Carmen Farid & Eman Saad. (2016) Serum thymic stromal lymphopoietin in pediatric atopic patients and its relation to the development of the atopic march. Journal of the Egyptian Womenʼs Dermatologic Society 13:3, pages 180-186.
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Akiko Shibui, Ayako Takamori, Mohammed E.M. Tolba, Aya Nambu, Eri Shimura, Sachiko Yamaguchi, Chizu Sanjoba, Hajime Suto, Katsuko Sudo, Ko Okumura, Sumio Sugano, Hideaki Morita, Hirohisa Saito, Kenji Matsumoto & Susumu Nakae. (2016) IL-25, IL-33 and TSLP receptor are not critical for development of experimental murine malaria. Biochemistry and Biophysics Reports 5, pages 191-195.
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Sebastian Reuter, Hendrik Beckert & Christian Taube. (2016) Take the Wnt out of the inflammatory sails: modulatory effects of Wnt in airway diseases. Laboratory Investigation 96:2, pages 177-185.
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Joanna Glück, Barbara Rymarczyk, Mirosława Kasprzak & Barbara Rogala. (2016) Increased Levels of Interleukin-33 and Thymic Stromal Lymphopoietin in Exhaled Breath Condensate in Chronic Bronchial Asthma. International Archives of Allergy and Immunology 169:1, pages 51-56.
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Katarzyna Górska, Patrycja Nejman-Gryz, Magdalena Paplińska-Goryca, Małgorzata Proboszcz & Rafał Krenke. 2017. Pathobiology of Pulmonary Disorders. Pathobiology of Pulmonary Disorders 19 27 .
PD Mitchell, AI El-Gammal & PM O'Byrne. (2016) Emerging monoclonal antibodies as targeted innovative therapeutic approaches to asthma. Clinical Pharmacology & Therapeutics 99:1, pages 38-48.
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Brittany M. Salter, John Paul Oliveria, Graeme Nusca, Steve G. Smith, Rick M. Watson, Micheal Comeau, Roma Sehmi & Gail M. Gauvreau. (2015) Thymic stromal lymphopoietin activation of basophils in patients with allergic asthma is IL-3 dependent. Journal of Allergy and Clinical Immunology 136:6, pages 1636-1644.
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A. J. Baatjes, S. G. Smith, B. Dua, R. Watson, G. M. Gauvreau & P. M. O'Byrne. (2015) Treatment with anti-OX40L or anti-TSLP does not alter the frequency of T regulatory cells in allergic asthmatics. Allergy 70:11, pages 1505-1508.
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Chang-Hung Kuo & Chih-Hsing Hung. 2015. Allergy Bioinformatics. Allergy Bioinformatics 49 65 .

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