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Expert Opinion on Therapeutic Targets Volume 18, 2014 - Issue 10
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Atypical PKC: a target for treating insulin-resistant disorders of obesity, the metabolic syndrome and type 2 diabetes mellitus

Robert V FareseMedical and Research Services, James A. Haley Veterans Medical Center, 13000 Bruce B. Downs Blvd, Tampa, FL 33612, USA+1 813 972 2000 Ext. 4414; +1 813 972 7623; [email protected];University of South Florida College of Medicine, Division of Endocrinology and Metabolism, Department of Internal Medicine, Tampa, FL, USA
, MD,
Mackenzie C LeeMedical and Research Services, James A. Haley Veterans Medical Center, 13000 Bruce B. Downs Blvd, Tampa, FL 33612, USA+1 813 972 2000 Ext. 4414; +1 813 972 7623; [email protected];University of South Florida College of Medicine, Division of Endocrinology and Metabolism, Department of Internal Medicine, Tampa, FL, USA
&
Mini P SajanMedical and Research Services, James A. Haley Veterans Medical Center, 13000 Bruce B. Downs Blvd, Tampa, FL 33612, USA+1 813 972 2000 Ext. 4414; +1 813 972 7623; [email protected];University of South Florida College of Medicine, Division of Endocrinology and Metabolism, Department of Internal Medicine, Tampa, FL, USA
Pages 1163-1175 | Published online: 12 Sep 2014

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Jacques Gilloteaux, Kritika Subramanian, Nadia Solomon & Charles Nicaise. (2018) The leptin receptor mutation of the obese Zucker rat causes sciatic nerve demyelination with a centripetal pattern defect. Ultrastructural Pathology 42:5, pages 377-408.
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Lara Bellini, Mélanie Campana, Rana Mahfouz, Aurélie Carlier, Julien Véret, Christophe Magnan, Eric Hajduch & Hervé Le Stunff. (2015) Targeting sphingolipid metabolism in the treatment of obesity/type 2 diabetes. Expert Opinion on Therapeutic Targets 19:8, pages 1037-1050.
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Articles from other publishers (15)

Qian Xiao, Dan Wang, Danyang Li, Jing Huang, Feifei Ma, Haocheng Zhang, Yingda Sheng, Caimei Zhang & Xiaoqin Ha. (2023) Protein kinase C: A potential therapeutic target for endothelial dysfunction in diabetes. Journal of Diabetes and its Complications 37:9, pages 108565.
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Jingya Liao, Ziwei Yang, Yanhong Yao, Xinzhou Yang, Jinhua Shen & Ping Zhao. (2022) Andrographolide Promotes Uptake of Glucose and GLUT4 Transport through the PKC Pathway in L6 Cells. Pharmaceuticals 15:11, pages 1346.
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Thiago M. Batista, Ashok Kumar Jayavelu, Nicolai J. Wewer Albrechtsen, Salvatore Iovino, Jasmin Lebastchi, Hui Pan, Jonathan M. Dreyfuss, Anna Krook, Juleen R. Zierath, Matthias Mann & C. Ronald Kahn. (2020) A Cell-Autonomous Signature of Dysregulated Protein Phosphorylation Underlies Muscle Insulin Resistance in Type 2 Diabetes. Cell Metabolism 32:5, pages 844-859.e5.
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Finbarr P.M. O'Harte, Vadivel Parthsarathy & Peter R. Flatt. (2020) Chronic apelin analogue administration is more effective than established incretin therapies for alleviating metabolic dysfunction in diabetic db/db mice. Molecular and Cellular Endocrinology 504, pages 110695.
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Ioannis AkoumianakisCharalambos Antoniades. (2019) Impaired Vascular Redox Signaling in the Vascular Complications of Obesity and Diabetes Mellitus. Antioxidants & Redox Signaling 30:3, pages 333-353.
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Ana Blázquez, Ángela Vázquez-Calvo, Miguel Martín-Acebes & Juan-Carlos Saiz. (2018) Pharmacological Inhibition of Protein Kinase C Reduces West Nile Virus Replication. Viruses 10:2, pages 91.
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Ashok K. Srivastava, Preeti Bajpai & Ashish Jain. 2018. Encyclopedia of Endocrine Diseases. Encyclopedia of Endocrine Diseases 100 104 .
Louise Mannerås-Holm, Milena Schönke, Joseph T. Brozinick, Laurène Vetterli, Hai-Hoang Bui, Philip Sanders, Emmani B.M. Nascimento, Marie Björnholm, Alexander V. Chibalin & Juleen R. Zierath. (2017) Diacylglycerol kinase ε deficiency preserves glucose tolerance and modulates lipid metabolism in obese mice. Journal of Lipid Research 58:5, pages 907-915.
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Mauricio D. Dorfman, Jordan E. Krull, Jarrad M. Scarlett, Stephan J. Guyenet, Mini P. Sajan, Vincent Damian, Hong T. Nguyen, Michael Leitges, Gregory J. Morton, Robert V. Farese, Michael W. Schwartz & Joshua P. Thaler. (2017) Deletion of Protein Kinase C λ in POMC Neurons Predisposes to Diet-Induced Obesity. Diabetes 66:4, pages 920-934.
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Theodore P. Ciaraldi. 2017. Principles of Diabetes Mellitus. Principles of Diabetes Mellitus 71 86 .
In Kyoung Mah, Rachel Soloff, Audrey K. Izuhara, Daniel L. Lakeland, Charles Wang & Francesca V. Mariani. (2016) Prkci is required for a non-autonomous signal that coordinates cell polarity during cavitation. Developmental Biology 416:1, pages 82-97.
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Qinwen BaoXiaozhu ShenLi QianChen GongMaoxiao NieYan Dong. (2016) Anti-diabetic activities of catalpol in db/db mice. The Korean Journal of Physiology & Pharmacology 20:2, pages 153.
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Haiyan Yu, Nobuharu L. Fujii, Taro Toyoda, Ding An, Robert V. Farese, Michael Leitges, Michael F. Hirshman, Joram D. Mul & Laurie J. Goodyear. (2015) Contraction stimulates muscle glucose uptake independent of atypical PKC. Physiological Reports 3:11, pages e12565.
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Matthew J. Bailey & Kenneth E. Prehoda. (2015) Establishment of Par-Polarized Cortical Domains via Phosphoregulated Membrane Motifs. Developmental Cell 35:2, pages 199-210.
Crossref
Theodore P. Ciaraldi. 2016. Principles of Diabetes Mellitus. Principles of Diabetes Mellitus 1 17 .

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