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Emerging Therapeutic Targets Volume 4, 2000 - Issue 2

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Structural basis for the action of drugs that affect microtubule dynamics

Kenneth H Downing Donner Laboratory, Life Sciences Division, Lawrence Berkeley National Laboratory, Berkeley, CA 94720, USA. [email protected]

Pages 219-237 | Published online: 25 Feb 2005

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https://doi.org/10.1517/14728222.4.2.219

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Mamika Minagawa, Minamo Shirato, Mika Toya & Masamitsu Sato. (2021) Dual Impact of a Benzimidazole Resistant β-Tubulin on Microtubule Behavior in Fission Yeast. Cells 10:5, pages 1042.
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C. Torres-Calzada, R. Tapia-Tussell, I. Higuera-Ciapara, R. Martin-MexA. Nexticapan-GarcezD. Perez-Brito. (2015) Sensitivity of Colletotrichum truncatum to Four Fungicides and Characterization of Thiabendazole-Resistant Isolates . Plant Disease 99:11, pages 1590-1595.
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Francesco Calogero, Stella Borrelli, Gaetano Speciale, Michael S. Christodoulou, Daniele Cartelli, Dario Ballinari, Francesco Sola, Clara Albanese, Antonella Ciavolella, Daniele Passarella, Graziella Cappelletti, Stefano Pieraccini & Maurizio Sironi. (2013) 9-Fluorenone-2-Carboxylic Acid as a Scaffold for Tubulin Interacting Compounds. ChemPlusChem 78:7, pages 663-669.
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Stefano Rendine, Stefano Pieraccini & Maurizio Sironi. (2010) Vinblastine perturbation of tubulin protofilament structure: a computational insight. Physical Chemistry Chemical Physics 12:47, pages 15530.
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Mythili Yenjerla, Corey Cox, Leslie Wilson & Mary Ann Jordan. (2009) Carbendazim Inhibits Cancer Cell Proliferation by Suppressing Microtubule Dynamics. Journal of Pharmacology and Experimental Therapeutics 328:2, pages 390-398.
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Alison N. Killilea, Kenneth H. Downing & David W. Killilea. (2007) Zinc deficiency reduces paclitaxel efficacy in LNCaP prostate cancer cells. Cancer Letters 258:1, pages 70-79.
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G.P. Brennan, I. Fairweather, A. Trudgett, E. Hoey, McCoy, M. McConville, M. Meaney, M. Robinson, N. McFerran, L. Ryan, C. Lanusse, L. Mottier, L. Alvarez, H. Solana, G. Virkel & P.M. Brophy. (2007) Understanding triclabendazole resistance. Experimental and Molecular Pathology 82:2, pages 104-109.
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Mark W. Robinson, Neil McFerran, Alan Trudgett, Liz Hoey & Ian Fairweather. (2004) A possible model of benzimidazole binding to β-tubulin disclosed by invoking an inter-domain movement. Journal of Molecular Graphics and Modelling 23:3, pages 275-284.
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Peter L Toogood. (2002) Progress toward the development of agents to modulate the cell cycle. Current Opinion in Chemical Biology 6:4, pages 472-478.
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Kenneth H. Downing. (2000) Structural Basis for the Interaction of Tubulin with Proteins and Drugs that Affect Microtubule Dynamics. Annual Review of Cell and Developmental Biology 16:1, pages 89-111.
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Structural basis for the action of drugs that affect microtubule dynamics

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