Advanced search
Publication Cover
Expert Opinion on Drug Safety Volume 7, 2008 - Issue 6
Submit an article Journal homepage
749
Views
99
CrossRef citations to date
0
Altmetric
Review

Gemcitabine: vascular toxicity and prothrombotic potential

Constantin A Dasanu Practicing Hematologist and Medical Oncologist, University Place, 2202 70th Ave W, Suite # 5, WA 98466, USA +1 253 301 4852; [email protected]
, MD PhD
Pages 703-716 | Published online: 04 Nov 2008

Citations (99)

Keep up to date with the latest research on this topic with citation updates for this article.

Subscribe to citation updates

Read on this site (5)

Xiangming Kong, Miao Feng, Lihuang Wu, Yiyan He, Hongli Mao & Zhongwei Gu. (2022) Biodegradable gemcitabine-loaded microdevice with sustained local drug delivery and improved tumor recurrence inhibition abilities for postoperative pancreatic tumor treatment. Drug Delivery 29:1, pages 1595-1607.
Read now
Zhila Mohajeri Avval, Leila Malekpour, Farzad Raeisi, Aziz Babapoor, Seyyed Mojtaba Mousavi, Seyyed Alireza Hashemi & Marjan Salari. (2020) Introduction of magnetic and supermagnetic nanoparticles in new approach of targeting drug delivery and cancer therapy application. Drug Metabolism Reviews 52:1, pages 157-184.
Read now
Tang Li, Li Chen, Yihui Deng, Xinrong Liu, Xiaoyun Zhao, Yiwen Cui, Jia Shi, Rui Feng & Yanzhi Song. (2017) Cholesterol derivative-based liposomes for gemcitabine delivery: preparation, in vitro, and in vivo characterization. Drug Development and Industrial Pharmacy 43:12, pages 2016-2025.
Read now
Cinzia Federico, Valeria M Morittu, Domenico Britti, Elena Trapasso & Donato Cosco. (2012) Gemcitabine-loaded liposomes: rationale, potentialities and future perspectives. International Journal of Nanomedicine 7, pages 5423-5436.
Read now
Christian Celia, Donato Cosco, Donatella Paolino & Massimo Fresta. (2011) Gemcitabine-loaded innovative nanocarriers vs GEMZAR: Biodistribution, pharmacokinetic features and in vivo antitumor activity. Expert Opinion on Drug Delivery 8:12, pages 1609-1629.
Read now

Articles from other publishers (94)

Alper Türkel, Mustafa Özdemir, Aziz Kurtuluş & Mutlu Doğan. (2023) Gemcitabine-associated digital necrosis in metastatic breast cancer. Journal of Oncology Pharmacy Practice 29:7, pages 1770-1775.
Crossref
Marta Rodríguez-Martínez, María Teresa García, José Manuel Pérez-Ortiz, Lucia González, Sergio Gómez-Alonso, Irene Álvarez Lara, Ignacio Gracia, Juan Francisco Rodríguez, Javier Redondo-Calvo, Esther García-Santos & David Padilla-Valverde. (2023) Preclinical safety study of a gemcitabine-controlled release polymer for locoregional administration in pancreatic cancer. Journal of Drug Delivery Science and Technology, pages 104843.
Crossref
Yasunori OtowaShun KishimotoYu SaidaKota YamashitaKazutoshi YamamotoGadisetti V.R. ChandramouliNallathamby DevasahayamJames B. MitchellMurali C. KrishnaJeffrey R. Brender. (2023) Evofosfamide and Gemcitabine Act Synergistically in Pancreatic Cancer Xenografts by Dual Action on Tumor Vasculature and Inhibition of Homologous Recombination DNA Repair. Antioxidants & Redox Signaling.
Crossref
Ertugrul Bayram, Tugba Toyran & Semra Paydas. (2023) Gemcitabine-associated DRESS syndrome: A case report. Journal of Oncology Pharmacy Practice, pages 107815522311675.
Crossref
Bijaideep Dutta, Sandeep B. Shelar, K. C. Barick, Priyalata Shetty, Rubel Chakravarty, Sudipta Chakraborty, Swati Checker, H. D. Sarma & P. A. Hassan. (2023) Surface engineered Fe 3 O 4 nanomagnets for pH-responsive delivery of gemcitabine hydrochloride and in vivo tracking by radiolabeling . Materials Advances 4:1, pages 195-204.
Crossref
悦 万. (2023) Research Progress in Drug Resistance and Structural Modification of Gemcitabine. Pharmacy Information 12:02, pages 81-86.
Crossref
Ahmed Alafnan, Aravindram Seetharam, Talib Hussain, Maram Gupta, Syed Rizvi, Afrasim Moin, Abdulwahab Alamri, Aziz Unnisa, Amir Awadelkareem, AbdElmoneim Elkhalifa, Pradyumna Jayahanumaiah, Mohammad Khalid & Natchimuthu Balashanmugam. (2022) Development and Characterization of PEGDA Microneedles for Localized Drug Delivery of Gemcitabine to Treat Inflammatory Breast Cancer. Materials 15:21, pages 7693.
Crossref
Abdul Moiz Khan, Lubina Arjyal, Lelas Shamaileh & Michael Simon. (2022) Gemcitabine-induced digital ischaemia in a patient with metastatic breast cancer. BMJ Case Reports 15:11, pages e252083.
Crossref
Alfonso Reginelli, Angelo Sangiovanni, Giovanna Vacca, Maria Paola Belfiore, Maria Pignatiello, Giuseppe Viscardi, Alfredo Clemente, Fabrizio Urraro & Salvatore Cappabianca. (2021) Chemotherapy-induced bowel ischemia: diagnostic imaging overview. Abdominal Radiology 47:5, pages 1556-1564.
Crossref
Shatha Abd Al-jabbar, Vesen Atiroğlu, Rana M. Hameed, Gamze Guney Eskiler, Atheer Atiroğlu, Asuman Deveci Ozkan & Mahmut Özacar. (2022) Fabrication of dopamine conjugated with protein @metal organic framework for targeted drug delivery: A biocompatible pH-Responsive nanocarrier for gemcitabine release on MCF‑7 human breast cancer cells. Bioorganic Chemistry 118, pages 105467.
Crossref
Maximilien Grall, Florence Daviet, Noémie Jourde Chiche, François Provot, Claire Presne, Jean-Philippe Coindre, Claire Pouteil-Noble, Alexandre Karras, Dominique Guerrot, Arnaud François, Ygal Benhamou, Agnès Veyradier, Véronique Frémeaux-Bacchi, Paul Coppo & Steven Grangé. (2021) Eculizumab in gemcitabine-induced thrombotic microangiopathy: experience of the French thrombotic microangiopathies reference centre. BMC Nephrology 22:1.
Crossref
Anroop B. Nair, Mallikarjun Telsang & Riyaz Ali Osmani. (2021) An Engineered Specificity of Anti-Neoplastic Agent Loaded Magnetic Nanoparticles for the Treatment of Breast Cancer. Polymers 13:21, pages 3623.
Crossref
Lucrezia Raimondi, Filippo Maria Raimondi, Luigi Rossi, Rachele Lazzeroni, Marta Pietranera, Laura Di Benedetto, Elisa Gozzi & Gian Paolo Spinelli. (2021) Gemcitabine-induced dilated-cardiomyopathy in patient with platinum-refractory ovarian-cancer: A case report and literature review. Journal of Oncology Pharmacy Practice 27:6, pages 1542-1547.
Crossref
Sandra Lee, Anika Shenoy, Daniel Shi, Mootaz Husien, Pablo E. Serrano & Sameer Parpia. (2021) Prognostic Factors for Venous Thromboembolism in Patients with Solid Tumours on Systemic Therapy: A Systematic Review. TH Open 05:03, pages e461-e469.
Crossref
Jia-Ling Ruan, Richard J. Browning, Yesna O. Yildiz, Luca Bau, Sukanta Kamila, Michael D. Gray, Lisa Folkes, Alix Hampson, Anthony P. McHale, John F. Callan, Borivoj Vojnovic, Anne E. Kiltie & Eleanor Stride. (2021) Evaluation of Loading Strategies to Improve Tumor Uptake of Gemcitabine in a Murine Orthotopic Bladder Cancer Model Using Ultrasound and Microbubbles. Ultrasound in Medicine & Biology 47:6, pages 1596-1615.
Crossref
C. Caradu, E. Ducasse & X. Bérard. (2021) Occlusioni aortiche acute. EMC - Tecniche Chirurgiche Vascolare 26:2, pages 1-21.
Crossref
Pooja Manjarekar & Tabassum Khan. (2021) ANALYTICAL METHOD DEVELOPMENT AND VALIDATION STUDIES OF GEMCITABINE NIOSOMES. INDIAN DRUGS 57:11, pages 45-51.
Crossref
Chengli Dai, Zheng Tang, Xiaoling Li & Tianfeng Chen. (2021) High-pressure homogenization and tailoring of size-tunable Ganoderma lucidum spore oil nanosystem for enhanced anticancer therapy. Chemical Engineering Journal 406, pages 127125.
Crossref
Shweta Paroha, Juhi Verma, Ravindra Dhar Dubey, Rikeshwer Prasad Dewangan, Nagashekhara Molugulu, Ranjeet A. Bapat, Pravat Kumar Sahoo & Prashant Kesharwani. (2021) Recent advances and prospects in gemcitabine drug delivery systems. International Journal of Pharmaceutics 592, pages 120043.
Crossref
Florian Moik, Nick van Es, Florian Posch, Marcello Di Nisio, Thorsten Fuereder, Matthias Preusser, Ingrid Pabinger & Cihan Ay. (2020) Gemcitabine and Platinum-Based Agents for the Prediction of Cancer-Associated Venous Thromboembolism: Results from the Vienna Cancer and Thrombosis Study. Cancers 12:9, pages 2493.
Crossref
Aristotelis Bamias, Kimon Tzannis, Ioannis Dimitriadis, Georgios Tsironis, Alkistis-Maria Papatheorodidi, Anna Tsiara, Charalampos Fragkoulis, Aikaterini Xirokosta, Despoina Barbarousi, Georgios Papadopoulos, Roubini Zakopoulou, Ioannis Varkarakis, Iraklis Mitsogiannis, Ioannis Adamakis, Christos Alamanis, Konstantinos Stravodimos, Athanasios G. Papatsoris, Athanasios E. Dellis, Alexandros Drivalos, Konstantinos Ntoumas, Haris Matsouka, Panayiotis Halvatsiotis, Athanasios Raptis, Grigorios T. Gerotziafas & Meletios Athanasios Dimopoulos. (2020) Risk for Venous Thromboembolic Events in Patients With Advanced Urinary Tract Cancer Treated With First-Line Chemotherapy. Clinical Genitourinary Cancer 18:4, pages e457-e472.
Crossref
Ooi Xue Ting, Liau MeiQi May, Huang Jingxiang & Jaffar Huma. (2020) A case of exemestane induced pseudocellulitis. Dermatologic Therapy 33:4.
Crossref
C. Rodríguez-Nogales, S. Mura, P. Couvreur & M.J. Blanco-Prieto. (2020) Squalenoyl-gemcitabine/edelfosine nanoassemblies: Anticancer activity in pediatric cancer cells and pharmacokinetic profile in mice. International Journal of Pharmaceutics 582, pages 119345.
Crossref
Magdalena Zaborowska-Szmit, Maciej Krzakowski, Dariusz M. Kowalski & Sebastian Szmit. (2020) Cardiovascular Complications of Systemic Therapy in Non-Small-Cell Lung Cancer. Journal of Clinical Medicine 9:5, pages 1268.
Crossref
Hiroyasu Takemoto, Takanori Inaba, Takahiro Nomoto, Makoto Matsui, Xiaomeng Liu, Masahiro Toyoda, Yuto Honda, Kaori Taniwaki, Naoki Yamada, Junhyun Kim, Keishiro Tomoda & Nobuhiro Nishiyama. (2020) Polymeric modification of gemcitabine via cyclic acetal linkage for enhanced anticancer potency with negligible side effects. Biomaterials 235, pages 119804.
Crossref
Ezgi Guler, Daniel A. Smith, Bhanusupriya Somarouthu, Rahul Gujrathi, Nikhil H. Ramaiya & Sree Harsha Tirumani. (2019) Overview of imaging findings associated with systemic therapies in advanced epithelial ovarian cancer. Abdominal Radiology 45:3, pages 828-841.
Crossref
Charles Sutton, Yachao Zhang, DaeHee Kim, Hooman Yarmohammadi, Etay Ziv, Franz E. Boas, Constantinos T. Sofocleous, William D. Tap, Sandra P. D’Angelo & Joseph P. Erinjeri. (2020) Analysis of the Chemotherapy-Free Interval following Image-Guided Ablation in Sarcoma Patients. Sarcoma 2020, pages 1-8.
Crossref
Karam Khaddour, Veerpal Singh & Maryna Shayuk. (2019) Acral vascular necrosis associated with immune-check point inhibitors: case report with literature review. BMC Cancer 19:1.
Crossref
Edit Gara, Kristóf György Csikó, Zoltán Ruzsa, Gábor Földes & Béla Merkely. (2019) Anti-cancer drugs-induced arterial injury: risk stratification, prevention, and treatment. Medical Oncology 36:8.
Crossref
Hassan Tamam, Jinho Park, Hytham H. Gadalla, Andrea R. Masters, Jelan A. Abdel-Aleem, Sayed I. Abdelrahman, Aly A. Abdelrahman, L. Tiffany Lyle & Yoon Yeo. (2019) Development of Liposomal Gemcitabine with High Drug Loading Capacity. Molecular Pharmaceutics 16:7, pages 2858-2871.
Crossref
Bryan M. Tucker & Randy L. Luciano. 2019. Glomerulonephritis. Glomerulonephritis 735 772 .
Dalvir Gill, Josh Schrader, Matthew Kelly, Fidel Martinez, Wajihuddin Syed & Jonathan Wright. (2017) Gemcitabine associated pseudocellulitis: A missed diagnosis. Journal of Oncology Pharmacy Practice 24:7, pages 550-552.
Crossref
Tahir Emre Yalcin, Sibel Ilbasmis-Tamer & Sevgi Takka. (2018) Development and characterization of gemcitabine hydrochloride loaded lipid polymer hybrid nanoparticles (LPHNs) using central composite design. International Journal of Pharmaceutics 548:1, pages 255-262.
Crossref
Alice ShanklinAndrew CoxHamdy M.A. AhmedAlicia LiebermanAnia Busza. (2018) Clinical Reasoning: A 77-year-old man presenting with episodic expressive aphasia. Neurology 90:20.
Crossref
Joanna Rupa-Matysek, Marta Lembicz, Eliza Katarzyna Rogowska, Lidia Gil, Mieczysław Komarnicki & Halina Batura-Gabryel. (2018) Evaluation of risk factors and assessment models for predicting venous thromboembolism in lung cancer patients. Medical Oncology 35:5.
Crossref
Kou‑Gi� ShyuMarappan� Velusamy, Chih‑Wei� HsiaChih‑Hao� YangChih‑Hsuan� HsiaDuen‑Suey� ChouThanasekaran� JayakumarJoen‑Rong� SheuJiun‑Yi� Li. (2018) Novel iridium (III)‑derived organometallic compound for the inhibition of human platelet activation. International Journal of Molecular Medicine.
Crossref
Maria Monica Haydock, Saroj Sigdel & Toni Pacioles. (2018) Gemcitabine-induced skin necrosis. SAGE Open Medical Case Reports 6, pages 2050313X1880926.
Crossref
Ren-Shi Shyu, Themmila Khamrang, Joen-Rong Sheu, Chih-Wei Hsia, Marappan Velusamy, Chih-Hsuan Hsia, Duen-Suey Chou & Chao-Chien Chang. (2018) Ir-6: A Novel Iridium (III) Organometallic Derivative for Inhibition of Human Platelet Activation. Bioinorganic Chemistry and Applications 2018, pages 1-14.
Crossref
Chih-Wei Hsia, Marappan Velusamy, Jeng-Ting Tsao, Chih-Hsuan Hsia, Duen-Suey Chou, Thanasekaran Jayakumar, Lin-Wen Lee, Jiun-Yi Li & Joen-Rong Sheu. (2017) New Therapeutic Agent against Arterial Thrombosis: An Iridium(III)-Derived Organometallic Compound. International Journal of Molecular Sciences 18:12, pages 2616.
Crossref
Devendra Manik Chavan, Zhen Huang, Kun Song, Leela Rani Haricharan Parimi, Xing Sheng Yang, Xiangning Zhang, Peishu Liu, Jie Jiang, Youzhong Zhang, Beihua Kong & Li Li. (2017) Incidence of venous thromboembolism following the neoadjuvant chemotherapy regimen for epithelial type of ovarian cancer. Medicine 96:42, pages e7935.
Crossref
Susanne R. Youngren-OrtizDavid B. HillPeter R. HoffmannKenneth R. MorrisEdward G. BarrettM. Gregory ForestMahavir B. Chougule. (2017) Development of Optimized, Inhalable, Gemcitabine-Loaded Gelatin Nanocarriers for Lung Cancer. Journal of Aerosol Medicine and Pulmonary Drug Delivery 30:5, pages 299-321.
Crossref
Chander Parkash Dora, Varun Kushwah, Sameer S. Katiyar, Pradeep Kumar, Viness Pillay, Sarasija Suresh & Sanyog Jain. (2017) Improved metabolic stability and therapeutic efficacy of a novel molecular gemcitabine phospholipid complex. International Journal of Pharmaceutics 530:1-2, pages 113-127.
Crossref
Amit Mittal & Jonathan S. Leventhal. (2017) Gemcitabine-associated acute lipodermatosclerosislike eruption: An underrecognized phenomenon. JAAD Case Reports 3:3, pages 190-195.
Crossref
Themmila Khamrang, Kuo-Chen Hung, Chih-Hsuan Hsia, Cheng-Ying Hsieh, Marappan Velusamy, Thanasekaran Jayakumar & Joen-Rong Sheu. (2017) Antiplatelet Activity of a Newly Synthesized Novel Ruthenium (II): A Potential Role for Akt/JNK Signaling. International Journal of Molecular Sciences 18:5, pages 916.
Crossref
Donya Mohebali, Jason Matos & James Ducksoon Chang. (2017) Gemcitabine induced cardiomyopathy: a case of multiple hit cardiotoxicity. ESC Heart Failure 4:1, pages 71-74.
Crossref
Eiichiro SoZachary D. CreesDanielle CritesAndrea Wang-Gillam. (2017) Digital Ischemia and Necrosis: A Rarely Described Complication of Gemcitabine in Pancreatic Adenocarcinoma. Journal of Pancreatic Cancer 3:1, pages 49-52.
Crossref
Bryan M. Tucker & Randy L. Luciano. 2017. Glomerulonephritis. Glomerulonephritis 1 36 .
Ravindra Dhar Dubey, Ankit Saneja, Prasoon K. Gupta & Prem N. Gupta. (2016) Recent advances in drug delivery strategies for improved therapeutic efficacy of gemcitabine. European Journal of Pharmaceutical Sciences 93, pages 147-162.
Crossref
Koji Matsuo, Aida Moeini, Hiroko Machida, Morgan E. Fullerton, Anastasiya Shabalova, Laurie L. Brunette & Lynda D. Roman. (2016) Significance of venous thromboembolism in women with cervical cancer. Gynecologic Oncology 142:3, pages 405-412.
Crossref
Maryam Parsian, Gozde Unsoy, Pelin Mutlu, Serap Yalcin, Aysen Tezcaner & Ufuk Gunduz. (2016) Loading of Gemcitabine on chitosan magnetic nanoparticles increases the anti-cancer efficacy of the drug. European Journal of Pharmacology 784, pages 121-128.
Crossref
R. Fuente, E.M. San Norberto, C. Flota, I. Estévez & C. Vaquero. (2016) Acrocianosis secundaria a quimioterapia con gemcitabina y cisplatino. Angiología 68:3, pages 242-243.
Crossref
Jun Ho Kim, Yong Sun Jeon & Soon Gu Cho. (2016) Successful management of four unusual cases of acute aortic thrombus induced by chemotherapy. Clinical Imaging 40:2, pages 224-227.
Crossref
Christopher M. Tully, Andrea B. Apolo, Emily C. Zabor, Ashley M. Regazzi, Irina Ostrovnaya, Helena F. Furberg, Jonathan E. Rosenberg & Dean F. Bajorin. (2015) The high incidence of vascular thromboembolic events in patients with metastatic or unresectable urothelial cancer treated with platinum chemotherapy agents. Cancer 122:5, pages 712-721.
Crossref
V. H. Giang Phan, Eunhye Lee, Jin Hee Maeng, Thavasyappan Thambi, Bong Sup Kim, Donheang Lee & Doo Sung Lee. (2016) Pancreatic cancer therapy using an injectable nanobiohybrid hydrogel. RSC Advances 6:47, pages 41644-41655.
Crossref
Arushi Khurana & Constantin A Dasanu. (2014) Posterior reversible encephalopathy syndrome due to targeted agents: vemurafinib among suspects!. Journal of Oncology Pharmacy Practice 21:6, pages 443-450.
Crossref
Hyunjin Ryu, Eunjeong Kang, Seokwoo Park, Sehoon Park, Kyoungbun Lee, Kwon Wook Joo & Hajeong Lee. (2015) A case of gemcitabine-induced thrombotic microangiopathy in a urothelial tumor patient with a single kidney. Kidney Research and Clinical Practice 34:4, pages 237-240.
Crossref
Constantin A Dasanu & Bruno Bockorny. (2014) Recurrent pseudocellulitis due to gemcitabine: Underrecognized and underreported?. Journal of Oncology Pharmacy Practice 21:5, pages 377-379.
Crossref
Pierre-Benoit Pagès, Valentin Derangere, Olivier Bouchot, Guy Magnin, Céline Charon-Barra, François Lokiec, François Ghiringhelli & Alain Bernard. (2015) Acute and delayed toxicity of gemcitabine administered during isolated lung perfusion: a preclinical dose-escalation study in pigs. European Journal of Cardio-Thoracic Surgery 48:2, pages 228-235.
Crossref
Ravindra Dhar Dubey, Noor Alam, Ankit Saneja, Vaibhav Khare, Ashok Kumar, Shagun Vaidh, Girish Mahajan, Parduman R. Sharma, Shashank K. Singh, Dilip M. Mondhe & Prem N. Gupta. (2015) Development and evaluation of folate functionalized albumin nanoparticles for targeted delivery of gemcitabine. International Journal of Pharmaceutics 492:1-2, pages 80-91.
Crossref
Wei Wu, Qing Xia, Rui-Jie Luo, Zi-Qi Lin & Ping Xue. (2015) In vitro Study of the Antagonistic Effect of Low-dose Liquiritigenin on Gemcitabine-induced Capillary Leak Syndrome in Pancreatic Adenocarcinoma via Inhibiting ROS-Mediated Signalling Pathways. Asian Pacific Journal of Cancer Prevention 16:10, pages 4369-4376.
Crossref
Muhammad F Khan, Silvija Gottesman, Ravichandra Boyella & Elizabeth Juneman. (2014) Gemcitabine-induced cardiomyopathy: a case report and review of the literature. Journal of Medical Case Reports 8:1.
Crossref
S Hayashi, S Maruoka, N Takahashi & S Hashimoto. (2014) Carotidynia after anticancer chemotherapy. Singapore Medical Journal 55:09, pages e142-e144.
Crossref
Maëlle Le Besnerais, Sébastien Miranda, Nicole Cailleux, Nicolas Girszyn, Isabelle Marie, Hervé Lévesque & Ygal Benhamou. (2014) Digital Ischemia Associated With Cancer. Medicine 93:10, pages e47.
Crossref
Rahul Nahire, Manas K. Haldar, Shirshendu Paul, Avinash H. Ambre, Varsha Meghnani, Buddhadev Layek, Kalpana S. Katti, Kara N. Gange, Jagdish Singh, Kausik Sarkar & Sanku Mallik. (2014) Multifunctional polymersomes for cytosolic delivery of gemcitabine and doxorubicin to cancer cells. Biomaterials 35:24, pages 6482-6497.
Crossref
Lionel Spielmann, Laurent Messer, Paul Moreau, Elodie Etienne, Carole Meyer, Jean Sibilia, Jacques-Eric Gottenberg, Bernard Geny, Béatrice Lannes & Alain Meyer. (2014) Gemcitabine-induced myopathy. Seminars in Arthritis and Rheumatism 43:6, pages 784-791.
Crossref
Michael Starck & Clemens-Martin Wendtner. (2014) Use of eculizumab in refractory gemcitabine-induced thrombotic microangiopathy. British Journal of Haematology 164:6, pages 894-896.
Crossref
Zhanna Livshits, Rama B. Rao & Silas W. Smith. (2014) An Approach to Chemotherapy-Associated Toxicity. Emergency Medicine Clinics of North America 32:1, pages 167-203.
Crossref
Ji Li, Yang Di, Chen Jin, Deliang Fu, Feng Yang, Yongjian Jiang, Lie Yao, Sijie Hao, Xiaoyi Wang, Sabin Subedi & Quanxing Ni. (2013) Gemcitabine-loaded albumin nanospheres (GEM-ANPs) inhibit PANC-1 cells in vitro and in vivo. Nanoscale Research Letters 8:1.
Crossref
Wei-Xiang Qi, Feng Lin, Yuan-Jue Sun, Li-Na Tang, Zan Shen & Yang Yao. (2013) Risk of venous and arterial thromboembolic events in cancer patients treated with gemcitabine: a systematic review and meta-analysis. British Journal of Clinical Pharmacology 76:3, pages 338-347.
Crossref
Atsuko Hosokawa, Toshihisa Nakashima, Yoshikazu Ogawa, Kazuhiro Kozawa & Takayoshi Kiba. (2012) Coadministration of 5% glucose solution relieves vascular pain in the patients administered gemcitabine immediately. Journal of Oncology Pharmacy Practice 19:2, pages 190-192.
Crossref
O. Sedlaczek, C. Grüllich, M. Röthke, H.-P. Schlemmer & H.-U. Kauczor. (2013) Organtoxizität medikamentöser TumortherapienOrgan toxicity of medicinal tumor therapy. Der Radiologe 53:4, pages 329-335.
Crossref
Donatella Paolino, Donato Cosco, Marilena Celano, Sonia Moretti, Efisio Puxeddu, Diego Russo & Massimo Fresta. (2013) Gemcitabine-loaded biocompatible nanocapsules for the effective treatment of human cancer. Nanomedicine 8:2, pages 193-201.
Crossref
So Ryoung SeongNamju LeeMi Jin LeeHyun Ah JangMin Ju SongSe Jung ParkJeeyoon KimBaek-Yeol Ryoo. (2013) A Study on Vascular Pain Due to Gemcitabine and According to Clinical Factors. Asian Oncology Nursing 13:4, pages 210.
Crossref
Jean M. Torrisi, Tunc A. Iyriboz & Han Xiao. 2013. Atlas of Genitourinary Oncological Imaging. Atlas of Genitourinary Oncological Imaging 231 245 .
José M. Mir‐Bonafé, Concepción Román‐Curto, Ángel Santos‐Briz, Javier Cañueto, Emilia Fernández‐López & Pablo Unamuno. (2012) Gemcitabine‐associated livedoid thrombotic microangiopathy with associated sclerema neonatorum‐like microscopic changes. Journal of Cutaneous Pathology 39:7, pages 707-711.
Crossref
Kang CaoJing YangChao LinBao-ning WangYuan YangJing ZhangJun DaiLei LiChun-lai NieZhu YuanMing-yuan Li. (2012) Noxa Enhances the Cytotoxic Effect of Gemcitabine in Human Ovarian Cancer Cells . Cancer Biotherapy and Radiopharmaceuticals 27:4, pages 259-266.
Crossref
Jacques Médioni, Jean-Paul Guastalla & Ludovic Drouet. (2012) Thrombose veineuse et cancer du sein. Bulletin du Cancer 99:2, pages 199-210.
Crossref
Sara D'epiro, Monica Salvi, Carlo Mattozzi, Simona Giancristoforo, Marco Campoli, Ramona Zanniello, Cecilia Luci, Laura Macaluso, Sara Giovannoni, Roberto Iacovelli, Stefano Calvieri & Antonio Giovanni Richetta. (2012) Gemcitabine-Induced Extensive Skin Necrosis. Case Reports in Medicine 2012, pages 1-3.
Crossref
Sandro Barni, Roberto Labianca, Giancarlo Agnelli, Erminio Bonizzoni, Melina Verso, Mario Mandalà, Matteo Brighenti, Fausto Petrelli, Carlo Bianchini, Tania Perrone & Giampietro Gasparini. (2011) Chemotherapy-associated thromboembolic risk in cancer outpatients and effect of nadroparin thromboprophylaxis: results of a retrospective analysis of the PROTECHT study. Journal of Translational Medicine 9:1.
Crossref
Synnöve Staff, Erja Lagerstedt, Janne Seppänen & Johanna Mäenpää. (2011) Acute digital ischemia complicating gemcitabine and carboplatin combination chemotherapy for ovarian cancer. Acta Obstetricia et Gynecologica Scandinavica 90:11, pages 1296-1297.
Crossref
F.A.B. Schutz, Y. Je, G.R. Azzi, P.L. Nguyen & T.K. Choueiri. (2011) Bevacizumab increases the risk of arterial ischemia: a large study in cancer patients with a focus on different subgroup outcomes. Annals of Oncology 22:6, pages 1404-1412.
Crossref
Elżbieta Senkus & Jacek Jassem. (2011) Cardiovascular effects of systemic cancer treatment. Cancer Treatment Reviews 37:4, pages 300-311.
Crossref
Elif Suyanı, Gülsan Türköz Sucak, Şahika Zeynep Akı, Zeynep Arzu Yeğin, Zübeyde Nur Özkurt & Münci Yağcı. (2010) Gemcitabine and vinorelbine combination is effective in both as a salvage and mobilization regimen in relapsed or refractory Hodgkin lymphoma prior to ASCT. Annals of Hematology 90:6, pages 685-691.
Crossref
Saurabh Sanon, Daniel J Lenihan & Elie Mouhayar. (2010) Peripheral arterial ischemic events in cancer patients. Vascular Medicine 16:2, pages 119-130.
Crossref
Donato Cosco, Donatella Paolino, Jessica Maiuolo, Diego Russo & Massimo Fresta. (2010) Liposomes as multicompartmental carriers for multidrug delivery in anticancer chemotherapy. Drug Delivery and Translational Research 1:1, pages 66-75.
Crossref
Jean M. Torrisi, Lawrence H. Schwartz, Marc J. Gollub, Michelle S. Ginsberg, George J. Bosl & Hedvig Hricak. (2011) CT Findings of Chemotherapy-induced Toxicity: What Radiologists Need to Know about the Clinical and Radiologic Manifestations of Chemotherapy Toxicity. Radiology 258:1, pages 41-56.
Crossref
C. Durant, P. Debourdeau & D. Farge. 2011. Traité de médecine vasculaire.. Traité de médecine vasculaire. 493 503 .
Dominique Stephan, Corina Miréa, Caroline Berthillot, Sébastien Gaertner & Marie Welsch. (2010) Nécroses digitales induites par la gemcitabine. La Presse Médicale 39:12, pages 1336-1338.
Crossref
A. B. Johan Groeneveld. (2010) What's New in Shock, November 2010?. Shock 34:5, pages 439-441.
Crossref
Takahiro Maeda, Eiji Kikuchi, Kazuhiro Matsumoto, Satoshi Yazawa, Jun Hagiuda, Akira Miyajima, Ken Nakagawa, Hirokazu Fujiwara, Haruhiko Hoshino & Mototsugu Oya. (2010) Gemcitabine and cisplatin chemotherapy induced reversible posterior leukoencephalopathy syndrome in a bladder cancer patient. International Journal of Clinical Oncology 15:5, pages 508-511.
Crossref
Michael Panella, Janice E. Ross, Keene Garvin & Alex Martin. (2010) Cardiac Sudden Death as a Result of Acute Coronary Artery Thrombosis During Chemotherapy for Testicular Carcinoma. Journal of Forensic Sciences 55:5, pages 1384-1388.
Crossref
M. Vassilakopoulou, G. Mountzios, C. Papamechael, A.D. Protogerou, K. Aznaouridis, P. Katsichti, K. Venetsanou, M.-A. Dimopoulos, I. Ikonomidis & C.A. Papadimitriou. (2010) Paclitaxel chemotherapy and vascular toxicity as assessed by flow-mediated and nitrate-mediated vasodilatation. Vascular Pharmacology 53:3-4, pages 115-121.
Crossref
Donatella Paolino, Donato Cosco, Leda Racanicchi, Elena Trapasso, Christian Celia, Michelangelo Iannone, Efisio Puxeddu, Giuseppe Costante, Sebastiano Filetti, Diego Russo & Massimo Fresta. (2010) Gemcitabine-loaded PEGylated unilamellar liposomes vs GEMZAR®: Biodistribution, pharmacokinetic features and in vivo antitumor activity. Journal of Controlled Release 144:2, pages 144-150.
Crossref
Cvetka Kuhar, Tanja Mesti & Branko Zakotnik. (2010) Digital ischemic events related to gemcitabine: Report of two cases and a systematic review. Radiology and Oncology 44:4.
Crossref

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.