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Proton pump inhibitors and clopidogrel: is it a significant drug interaction?

, PharmD & , PharmD FCCP FAHA
Pages 593-602 | Published online: 09 Apr 2010

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Michael C Wallace, Jamie Rankin & Geoffrey M Forbes. (2012) Acute gastrointestinal bleeding after percutaneous coronary intervention. Expert Review of Gastroenterology & Hepatology 6:2, pages 211-221.
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Pedro Amariles, Héctor Holguín, Nancy Yaneth Angulo, Piedad Maria Betancourth & Mauricio Ceballos. (2014) Efecto de la interacción clopidogrel-omeprazol en el reingreso hospitalario de pacientes por recidiva de síndrome coronario agudo: estudio de casos y controles. Atención Primaria 46:8, pages 426-432.
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Tatyana Zvyaga, Shu-Ying Chang, Cliff Chen, Zheng Yang, Ragini Vuppugalla, Jeremy Hurley, Denise Thorndike, Andrew Wagner, Anjaneya Chimalakonda & A. David Rodrigues. (2012) Evaluation of Six Proton Pump Inhibitors As Inhibitors of Various Human Cytochromes P450: Focus on Cytochrome P450 2C19. Drug Metabolism and Disposition 40:9, pages 1698-1711.
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S A Musa, S J Brecker, T M Rahman & J Y Kang. (2012) Upper gastrointestinal haemorrhage in the acute cardiac care setting: antiplatelets and endoscopy. Scottish Medical Journal 57:2, pages 88-91.
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Mitsuyo Kondo, Makiko Kawamoto, Atsushi Hasuoka, Masahiro Kajino, Nobuhiro Inatomi & Naoki Tarui. (2012) High-Throughput Screening of Potassium-Competitive Acid Blockers. SLAS Discovery 17:2, pages 177-182.
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Héctor Holguín, Mauricio Ceballos & Pedro Amariles. (2012) Relevancia clínica de la interacción clopidogrel y omeprazol: revisión sistemática. Revista Colombiana de Cardiología 19:1, pages 25-32.
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Tobias Gerhard. (2011) Clopidogrel and proton pump inhibitors: a clinically meaningful interaction?. Pharmacoepidemiology and Drug Safety 20:2, pages 214-218.
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Laurence J. Egan. (2011) Mechanisms of Drug Toxicity or Intolerance. Digestive Diseases 29:2, pages 172-176.
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J. Hankowitz & P. Bramlage. (2010) Pharmaka zur Thrombozyten- und Gerinnungshemmung in der Behandlung des akuten KoronarsyndromsPlatelet and coagulation inhibitors in the treatment of acute coronary syndrome. Der Kardiologe 4:3, pages 239-248.
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