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Impact of ATP-binding cassette, subfamily B, member 1 pharmacogenetics on tacrolimus-associated nephrotoxicity and dosage requirements in paediatric patients with liver transplant

, BSc PhD & , BSc PhD FPSNI FRPharmS FCPP
Pages 9-22 | Published online: 15 Jul 2010

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Dongdong Wang, Xiao Chen, Meng Fu, Hong Xu & Zhiping Li. (2020) Pharmacogenomics analysis in Chinese pediatric liver transplantation patients with renal toxicity induced by tacrolimus. Xenobiotica 50:4, pages 488-493.
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Articles from other publishers (11)

Fei Teng, Weiyue Zhang, Wei Wang, Jiani Chen, Shiyi Liu, Mingming Li, Lujin Li, Wenyuan Guo & Hua Wei. (2022) Population pharmacokinetics of tacrolimus in Chinese adult liver transplant patients. Biopharmaceutics & Drug Disposition 43:2, pages 76-85.
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Yanxia Lu, Li Xu, Jianrong Cui, Su Shen & Xingang Li. (2021) Effects of Postoperative Day and NR1I2 on Tacrolimus Clearance in Chinese Liver Transplant Recipients—A Population Model Approach . Clinical Pharmacology in Drug Development 10:11, pages 1385-1394.
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Camille Tron, Jean-Baptiste Woillard, Pauline Houssel-Debry, Véronique David, Caroline Jezequel, Michel Rayar, David Balakirouchenane, Benoit Blanchet, Jean Debord, Antoine Petitcollin, Mickaël Roussel, Marie-Clémence Verdier, Eric Bellissant & Florian Lemaitre. (2020) Pharmacogenetic—Whole blood and intracellular pharmacokinetic—Pharmacodynamic (PG-PK2-PD) relationship of tacrolimus in liver transplant recipients. PLOS ONE 15:3, pages e0230195.
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T.-H. Yang, Y.-K. Chen, F. Xue, L.-Z. Han, C.-H. Shen, T. Zhou, Y. Luo, J.-J. Zhang & Q. Xia. (2015) Influence of CYP3A5 genotypes on tacrolimus dose requirement: age and its pharmacological interaction with ABCB1 genetics in the Chinese paediatric liver transplantation . International Journal of Clinical Practice 69, pages 53-62.
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Yi-kuan Chen, Long-zhi Han, Feng Xue, Cong-huan Shen, Jun Lu, Tai-hua Yang, Jian-jun Zhang & Qiang Xia. (2014) Personalized Tacrolimus Dose Requirement by CYP3A5 but Not ABCB1 or ACE Genotyping in Both Recipient and Donor after Pediatric Liver Transplantation. PLoS ONE 9:10, pages e109464.
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Mariam H. Abdel Jalil, Ahmed F. Hawwa, Patrick J. McKiernan, Michael D. Shields & James C. McElnay. (2014) Population pharmacokinetic and pharmacogenetic analysis of tacrolimus in paediatric liver transplant patients. British Journal of Clinical Pharmacology 77:1, pages 130-140.
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Barkur S. Shastry. 2014. Pharmacogenomics in Drug Discovery and Development. Pharmacogenomics in Drug Discovery and Development 671 685 .
Yuan-Yuan Liu, Changping Li, Zhuang Cui, Xiaomeng Fu, Shu Zhang, Lin-Lin Fan, Jun Ma & Guang Li. (2013) The effect of ABCB1 C3435T polymorphism on pharmacokinetics of tacrolimus in liver transplantation: A meta-analysis. Gene 531:2, pages 476-488.
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Miguel Angel Gómez-Bravo, Magdalena Salcedo, Constantino Fondevila, Francisco Suarez, José Castellote, Sebastián Rufian, José Antonio Pons, José María Alamo, Olga Millán & Mercè Brunet. (2013) Impact of donor and recipient CYP3A5 and ABCB1 genetic polymorphisms on tacrolimus dosage requirements and rejection in Caucasian Spanish liver transplant patients. The Journal of Clinical Pharmacology, pages n/a-n/a.
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Violette Gijsen, Seema Mital, Ron H. van Schaik, Offie P. Soldin, Steven J. Soldin, Ilse P. van der Heiden, Irena Nulman, Gideon Koren & Saskia N. de Wildt. (2011) Age and CYP3A5 genotype affect tacrolimus dosing requirements after transplant in pediatric heart recipients. The Journal of Heart and Lung Transplantation 30:12, pages 1352-1359.
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Saskia N. de Wildt, Ron H. N. van Schaik, Offie P. Soldin, Steve J. Soldin, Parvaneh Yazdani Brojeni, Ilse P. van der Heiden, Chris Parshuram, Irena Nulman & Gideon Koren. (2011) The interactions of age, genetics, and disease severity on tacrolimus dosing requirements after pediatric kidney and liver transplantation. European Journal of Clinical Pharmacology 67:12, pages 1231-1241.
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