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Expert Opinion on Drug Safety Volume 11, 2012 - Issue 2
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Diabetes and fracture healing: the skeletal effects of diabetic drugs

Christopher M Simpsona University of Leeds, Leeds Teaching Hospitals NHS Trust, School of Medicine, Academic Dept. of Trauma and Orthopaedics, Leeds, UK
, MBChB, BSc,
Giorgio M Calorib University of Milan, Department of Trauma and Orthopaedics, Milan, Italy
, MD &
Peter V Giannoudisa University of Leeds, Leeds Teaching Hospitals NHS Trust, School of Medicine, Academic Dept. of Trauma and Orthopaedics, Leeds, UK;c University of Leeds, School of Medicine, Academic Department of Trauma and Orthopaedics, Leeds General Infirmary, Clarendon wing Level A, Great George Street, LS1 3EX, Leeds, UK+44 0 113 392 2750; +44 0 113 392 3290; [email protected]
, BSc MD FRCS
Pages 215-220 | Published online: 06 Dec 2011

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Eric J Campbell, Graeme M Campbell & David A Hanley. (2015) The effect of parathyroid hormone and teriparatide on fracture healing. Expert Opinion on Biological Therapy 15:1, pages 119-129.
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Idoia Páramo-CastillejoRaquel Fernández-PenasIsmael Romero-CastilloAlicia Domínguez-Martín, Elena López-Ruiz, Jorge Fernando Fernández Sánchez, Duane Choquesillo LazarteJuan Antonio Marchal & Jaime Gómez-Morales. (2022) Type I Collagen-Apatite Fibrillar Nanocomposites: Mineralization, Crosslinking and Anti-Inflammatory Cocrystal Impregnation for Bone Tissue Engineering. Solid State Phenomena 339, pages 95-100.
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Jana Blahova, Monika Martiniakova, Martina Babikova, Veronika Kovacova, Vladimira Mondockova & Radoslav Omelka. (2021) Pharmaceutical Drugs and Natural Therapeutic Products for the Treatment of Type 2 Diabetes Mellitus. Pharmaceuticals 14:8, pages 806.
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Wojciech Glinkowski & Alexander N. Chelnokov. (2021) The orthopaedic surgeon's clinical and experimental experience affect methods used for the fracture healing assessment (FHA) – An International Survey. Injury 52:8, pages 2205-2214.
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W. Blake Martin, Renaud Sicard, Shabnam M. Namin & Timothy Ganey. (2019) Methods of Cryoprotectant Preservation: Allogeneic Cellular Bone Grafts and Potential Effects. BioMed Research International 2019, pages 1-7.
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Simon Lau & Melissa Lee. (2019) Hyperglycaemia is an under-appreciated but modifiable risk factor in managing people with type 1 diabetes and fragility fractures. The Foot 40, pages 43-45.
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Julie Manon, Christine Detrembleur, Simon Van de Veyver, Karim Tribak, Olivier Cornu & Dan Putineanu. (2019) Quels sont les facteurs prédictifs d’une complication mécanique après enclouage centromédullaire d’une fracture diaphysaire du tibia ?. Revue de Chirurgie Orthopédique et Traumatologique 105:3, pages 353-357.
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Julie Manon, Christine Detrembleur, Simon Van de Veyver, Karim Tribak, Olivier Cornu & Dan Putineanu. (2019) Predictors of mechanical complications after intramedullary nailing of tibial fractures. Orthopaedics & Traumatology: Surgery & Research 105:3, pages 523-527.
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Yurie Taguchi, Yuta Inoue, Taichi Kido & Nobuhiro Arai. (2018) Treatment costs and cost drivers among osteoporotic fracture patients in Japan: a retrospective database analysis. Archives of Osteoporosis 13:1.
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Yuchen Wang, Maureen R. Newman & Danielle S.W. Benoit. (2018) Development of controlled drug delivery systems for bone fracture-targeted therapeutic delivery: A review. European Journal of Pharmaceutics and Biopharmaceutics 127, pages 223-236.
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Chrisitan Kasperk. 2018. Diabetes-Therapie – informiert entscheiden. Diabetes-Therapie – informiert entscheiden 41 43 .
Takao Aikawa, Hidenori Matsubara, Shuhei Ugaji, Junichi Shirakawa, Ryoji Nagai, Seiichi Munesue, Ai Harashima, Yasuhiko Yamamoto & Hiroyuki Tsuchiya. (2017) Contribution of methylglyoxal to delayed healing of bone injury in diabetes. Molecular Medicine Reports 16:1, pages 403-409.
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M. Miska, G. Schmidmaier & M.-A. Weber. 2017. Kompendium Orthopädische Bildgebung. Kompendium Orthopädische Bildgebung 411 426 .
Markus Neumaier & Peter Biberthaler. 2017. Knochendefekte und Pseudarthrosen. Knochendefekte und Pseudarthrosen 77 100 .
Matthias Miska, Arash Moghaddam-Alvandi & Gerhard Schmidmaier. 2017. Knochendefekte und Pseudarthrosen. Knochendefekte und Pseudarthrosen 167 190 .
Matthew P. Gilbert, Michel. Marre, Jens Juul. Holst, Alan. Garber, Florian M.M. Baeres, Henrik. Thomsen & Richard E. Pratley. (2016) Comparison Of The Long-Term Effects Of Liraglutide And Glimepiride Monotherapy On Bone Mineral Density In Patients With Type 2 Diabetes. Endocrine Practice 22:4, pages 406-411.
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Peter V. Giannoudis, David Hak, David Sanders, Erin Donohoe, Theodoros Tosounidis & Chelsea Bahney. (2015) Inflammation, Bone Healing, and Anti-Inflammatory Drugs. Journal of Orthopaedic Trauma 29:Supplement 12, pages S6-S9.
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C. Simpson, D. Jayaramaraju, D. Agraharam, S. Gudipati, R. Shanmuganathan & P. V. Giannoudis. (2015) The effects of diabetes medications on post-operative long bone fracture healing. European Journal of Orthopaedic Surgery & Traumatology 25:8, pages 1239-1243.
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Jane E. Corrarino. (2015) Fracture Repair: Mechanisms and Management. The Journal for Nurse Practitioners 11:10, pages 960-967.
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Theodoros H. Tosounidis, Hassaan Sheikh, Martin H. Stone & Peter V. Giannoudis. (2015) Pain relief management following proximal femoral fractures: Options, issues and controversies. Injury 46, pages S52-S58.
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Hsin-Hung Chen, Ming-Hwarng Horng, Su-Yin Yeh, I-Ching Lin, Chih-Jung Yeh, Chih-Hsin Muo, Fung-Chang Sung & Chia-Hung Kao. (2015) Glycemic Control with Thiazolidinedione Is Associated with Fracture of T2DM Patients. PLOS ONE 10:8, pages e0135530.
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A. Capone, G. Marongiu & R. Sirianni. (2015) L’osteogenesi riparativaReparative osteogenesis. LO SCALPELLO-OTODI Educational 29:1, pages 2-9.
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Yukinori TAMURA, Osamu MATSUO & Hiroshi KAJI. (2015) Role of plasmionogen activator inhibitor-1 in the pathogenesis of bone metabolism abnormalities. Japanese Journal of Thrombosis and Hemostasis 26:6, pages 619-625.
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G.M. Calori, M. Colombo, E.L. Mazza, S. Mazzola, E. Malagoli, N. Marelli & A. Corradi. (2014) Validation of the Non-Union Scoring System in 300 long bone non-unions. Injury 45, pages S93-S97.
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M. Amling, R. Oheim & F. Barvencik. (2014) A holistic hip fracture approach: individualized diagnosis and treatment after surgery. European Journal of Trauma and Emergency Surgery 40:3, pages 265-271.
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Li Mao, Yukinori Tamura, Naoyuki Kawao, Kiyotaka Okada, Masato Yano, Katsumi Okumoto & Hiroshi Kaji. (2014) Influence of diabetic state and vitamin D deficiency on bone repair in female mice. Bone 61, pages 102-108.
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Li Mao, Naoyuki Kawao, Yukinori Tamura, Katsumi Okumoto, Kiyotaka Okada, Masato Yano, Osamu Matsuo & Hiroshi Kaji. (2014) Plasminogen Activator Inhibitor-1 Is Involved in Impaired Bone Repair Associated with Diabetes in Female Mice. PLoS ONE 9:3, pages e92686.
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Cem Copuroglu, Giorgio M. Calori & Peter V. Giannoudis. (2013) Fracture non-union: Who is at risk?. Injury 44:11, pages 1379-1382.
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G.M. Calori, M. Colombo, E. Mazza, C. Ripamonti, S. Mazzola, N. Marelli & G.V. Mineo. (2013) Monotherapy vs. polytherapy in the treatment of forearm non-unions and bone defects. Injury 44, pages S63-S69.
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