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Expert Opinion on Drug Safety Volume 11, 2012 - Issue 4
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Drug Safety Evaluations

Safety and efficacy of aliskiren in the treatment of hypertension: a systematic overview

Fabio AngeliHospital Media Valle del Tevere – Pantalla, AUSL 2 Umbria, Department of Cardiology, Section of Cardiology, Perugia, Italy+39 075 8880611; [email protected]
, MD,
Gianpaolo ReboldiUniversity of Perugia, Department of Internal Medicine, Perugia, Italy
, MD PhD MSc,
Giovanni MazzottaHospital of Assisi, Department of Internal Medicine, Assisi, Italy
, MD,
Cristina PoltronieriHospital Media Valle del Tevere – Pantalla, AUSL 2 Umbria, Department of Cardiology, Section of Cardiology, Perugia, Italy+39 075 8880611; [email protected]
, MD &
Paolo VerdecchiaHospital of Assisi, Department of Internal Medicine, Assisi, Italy
, MD FAHA FESC
Pages 659-670 | Published online: 23 Jun 2012

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Gérard Vergoten & Christian Bailly. (2022) Interaction of the renin inhibitor aliskiren with the SARS-CoV-2 main protease: a molecular docking study. Journal of Biomolecular Structure and Dynamics 40:23, pages 12714-12722.
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Articles from other publishers (15)

Annabella Braschi. (2019) Potential Protective Role of Blood Pressure-Lowering Drugs on the Balance between Hemostasis and Fibrinolysis in Hypertensive Patients at Rest and During Exercise. American Journal of Cardiovascular Drugs 19:2, pages 133-171.
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Marco Allinovi, Letizia De Chiara, Maria Lucia Angelotti, Francesca Becherucci & Paola Romagnani. (2018) Anti-fibrotic treatments: A review of clinical evidence. Matrix Biology 68-69, pages 333-354.
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Raymond G. Schlienger, Jonathan R. Korn, Elizabeth Wehler, Sandra Lopez Leon & Jason Yeaw. (2017) Angioedema Among Hypertensive Patients Treated with Aliskiren or Other Antihypertensive Medications in the United States. American Journal of Cardiovascular Drugs 17:6, pages 465-474.
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Takashi Uzu, Shin-ichi Araki, Atsunori Kashiwagi, Masakazu Haneda, Daisuke Koya, Hiroki Yokoyama, Yasuo Kida, Motoyoshi Ikebuchi, Takaaki Nakamura, Masataka Nishimura, Noriko Takahara, Toshiyuki Obata, Nobuyuki Omichi, Katsuhiko Sakamoto, Ryosuke Shingu, Hideki Taki, Yoshio Nagai, Hiroaki Tokuda, Munehiro Kitada, Miwa Misawa, Akira Nishiyama, Hiroyuki Kobori & Hiroshi Maegawa. (2016) Comparative Effects of Direct Renin Inhibitor and Angiotensin Receptor Blocker on Albuminuria in Hypertensive Patients with Type 2 Diabetes. A Randomized Controlled Trial. PLOS ONE 11:12, pages e0164936.
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. 2016. Meyler's Side Effects of Drugs. Meyler's Side Effects of Drugs 147 149 .
Lawrence R. Krakoff. (2015) Blood Pressure Out of the Office: Its Time Has Finally Come. American Journal of Hypertension, pages hpv179.
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Alice P.S. Kong & Juliana C.N. Chan. 2015. International Textbook of Diabetes Mellitus. International Textbook of Diabetes Mellitus 564 573 .
Dionne Mayhew Hines, Catherine Balderston McGuiness, Raymond Gilles Schlienger & Charles Makin. (2015) Incidence of Ischemic Colitis in Treated, Commercially Insured Hypertensive Adults: A Cohort Study of US Health Claims Data. American Journal of Cardiovascular Drugs 15:2, pages 135-149.
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Sai-Wang Seto, Smriti M. Krishna, Corey S. Moran, David Liu & Jonathan Golledge. (2014) Aliskiren limits abdominal aortic aneurysm, ventricular hypertrophy and atherosclerosis in an apolipoprotein-E-deficient mouse model. Clinical Science 127:2, pages 123-134.
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N. Voigt, J. Heijman & D. Dobrev. (2014) Kardiovaskuläre PharmakotherapieCardiovascular pharmacotherapy. Herz 39:2, pages 227-240.
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Graziano Riccioni. (2013) The role of direct renin inhibitors in the treatment of the hypertensive diabetic patient. Therapeutic Advances in Endocrinology and Metabolism 4:5, pages 139-145.
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Cheuk-Chun Szeto, Bonnie Ching-Ha Kwan, Kai-Ming Chow, Chi-Bon Leung & Philip Kam-Tao Li. (2013) The Safety and Short-Term Efficacy of Aliskiren in the Treatment of Immunoglobulin A Nephropathy – A Randomized Cross-Over Study. PLoS ONE 8:5, pages e62736.
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Rhian M. Touyz. (2013) Combination Antihypertensive Treatment With Aliskiren and Blockers of the Renin-Angiotensin System—Reassurance but With a Note of Caution. Canadian Journal of Cardiology 29:5, pages 521-523.
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Asadur Rahman, Koji Ohmori, Masakazu Kohno & Akira Nishiyama. (2013) Effects of angiotensin-converting enzyme inhibitors and angiotensin II receptor blockers on accumulation of aliskiren in the kidney. Journal of Hypertension 31:4, pages 659-660.
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Kazushi Tsuda. (2012) Renin-Angiotensin System and Sympathetic Neurotransmitter Release in the Central Nervous System of Hypertension. International Journal of Hypertension 2012, pages 1-11.
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