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Effects of 5-alpha reductase inhibitors on erectile function, sexual desire and ejaculation

, & , MD FACS
Pages 81-90 | Published online: 22 Nov 2012

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Sandro La Vignera, Antonio Aversa, Rossella Cannarella, Rosita A. Condorelli, Ylenia Duca, Giorgio I. Russo & Aldo E. Calogero. (2021) Pharmacological treatment of lower urinary tract symptoms in benign prostatic hyperplasia: consequences on sexual function and possible endocrine effects. Expert Opinion on Pharmacotherapy 22:2, pages 179-189.
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Andrea Russo, Paolo Capogrosso, Giovanni La Croce, Eugenio Ventimiglia, Luca Boeri, Alberto Briganti, Rocco Damiano, Francesco Montorsi & Andrea Salonia. (2016) Serenoa repens, selenium and lycopene to manage lower urinary tract symptoms suggestive for benign prostatic hyperplasia. Expert Opinion on Drug Safety 15:12, pages 1661-1670.
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Articles from other publishers (58)

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Claus G. Roehrborn & Daniel B. Rukstalis. (2022) Prostatic Urethral Lift Versus Medical Therapy: Examining the Impact on Sexual Function in Men with Benign Prostatic Hyperplasia. European Urology Focus 8:1, pages 217-227.
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Vincenzo Favilla, Rossella Cannarella, Federica Trovato, Giovanni Li Volti, Alfio Distefano, Enrico Grimaldi, Giuseppa La Camera, Sandro La Vignera, Rosita A. Condorelli, Aldo E. Calogero & Sebastiano Cimino. (2021) Effects of dutasteride on sex hormones and cerebrospinal steroids in patients treated for benign prostatic hyperplasia. Endocrine 73:3, pages 712-718.
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Ahra Cho, Bilal Chughtai & Alexis E. Te. (2020) Benign Prostatic Hyperplasia and Male Lower Urinary Tract Symptoms: Epidemiology and Risk Factors. Current Bladder Dysfunction Reports 15:2, pages 60-65.
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Abdulmaged M. Traish. (2020) Post-finasteride syndrome: a surmountable challenge for clinicians. Fertility and Sterility 113:1, pages 21-50.
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R.S. Haber, A.K. Gupta, E. Epstein, J.L. Carviel & K.A. Foley. (2019) Finasteride for androgenetic alopecia is not associated with sexual dysfunction: a survey‐based, single‐centre, controlled study. Journal of the European Academy of Dermatology and Venereology 33:7, pages 1393-1397.
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Robert S. Haber, Aditya K. Gupta, Edwin S. Epstein, J.L. Carviel & K.A. Foley. (2019) Finasteride for Androgenetic Alopecia Is Not Associated with Sexual Dysfunction: A Survey-Based, Single-Centre, Controlled Study. International Society of Hair Restoration Surgery 29:3, pages 89-96.
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Jae Heon Kim, Min Jung Baek, Hwa Yeon Sun, Bora Lee, Shufeng Li, Yash Khandwala, Francesco Del Giudice & Benjamin I. Chung. (2018) Efficacy and safety of 5 alpha-reductase inhibitor monotherapy in patients with benign prostatic hyperplasia: A meta-analysis. PLOS ONE 13:10, pages e0203479.
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J.S. Mervis, L.J. Borda & M. Miteva. (2018) ‘Post-finasteride syndrome’: what to tell our female patients?. British Journal of Dermatology 179:3, pages 785-786.
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Abdulmaged M. Traish. (2018) The Post-finasteride Syndrome: Clinical Manifestation of Drug-Induced Epigenetics Due to Endocrine Disruption. Current Sexual Health Reports 10:3, pages 88-103.
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Silvia Giatti, Silvia Diviccaro, Giancarlo Panzica & Roberto Cosimo Melcangi. (2018) Post-finasteride syndrome and post-SSRI sexual dysfunction: two sides of the same coin?. Endocrine 61:2, pages 180-193.
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Mary K. Samplaski & Ajay K. Nangia. 2018. Encyclopedia of Reproduction. Encyclopedia of Reproduction 207 216 .
Norhayati Mohamed Noor, Khalid Sheikh, Satyanarayana Somavarapu & Kevin M.G. Taylor. (2017) Preparation and characterization of dutasteride-loaded nanostructured lipid carriers coated with stearic acid-chitosan oligomer for topical delivery. European Journal of Pharmaceutics and Biopharmaceutics 117, pages 372-384.
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G. Corona, G. Tirabassi, D. Santi, E. Maseroli, M. Gacci, M. Dicuio, A. Sforza, E. Mannucci & M. Maggi. (2017) Sexual dysfunction in subjects treated with inhibitors of 5α-reductase for benign prostatic hyperplasia: a comprehensive review and meta-analysis. Andrology 5:4, pages 671-678.
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Abdulmaged Traish, Karim Sultan Haider, Gheorghe Doros & Ahmad Haider. (2017) Long-term dutasteride therapy in men with benign prostatic hyperplasia alters glucose and lipid profiles and increases severity of erectile dysfunction. Hormone Molecular Biology and Clinical Investigation 30:3.
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N. Enatsu, K. Chiba, K. Sumii, T. Fukuda, K. Okada, K. Matsushita & M. Fujisawa. (2017) Dutasteride-mediated morphological changes in the genitourinary tract associated with altered expression patterns of the androgen and estrogen receptors in male rats. Andrology 5:2, pages 347-353.
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Francisco J. Garcia, Eric Chung & Gerald Brock. 2017. Male Sexual Dysfunction. Male Sexual Dysfunction 172 193 .
Abdulmaged M. Traish. 2017. Sex and Gender Factors Affecting Metabolic Homeostasis, Diabetes and Obesity. Sex and Gender Factors Affecting Metabolic Homeostasis, Diabetes and Obesity 473 526 .
Charles Welliver & Ahmed Essa. (2016) Sexual Side Effects of Medical and Surgical Benign Prostatic Hyperplasia Treatments. Urologic Clinics of North America 43:3, pages 393-404.
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Steven A. Kaplan, Jeannette Y. Lee, Alan G. Meehan & John W. Kusek. (2016) Time Course of Incident Adverse Experiences Associated with Doxazosin, Finasteride and Combination Therapy in Men with Benign Prostatic Hyperplasia: The MTOPS Trial. The Journal of Urology 195:6, pages 1825-1829.
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Giovanni Corona. (2016) Editorial Comment on “Erectile and Ejaculatory Function Preserved With Convective Water Vapor Energy Treatment of Lower Urinary Tract Symptoms Secondary to Benign Prostatic Hyperplasia: Randomized Controlled Study”. The Journal of Sexual Medicine 13:6, pages 934-935.
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Abdulmaged M. Traish, Karim Sultan Haider, Gheorghe Doros & Ahmad Haider. (2015) Finasteride, not tamsulosin, increases severity of erectile dysfunction and decreases testosterone levels in men with benign prostatic hyperplasia. Hormone Molecular Biology and Clinical Investigation 23:3, pages 85-96.
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Thiagarajan Madheswaran, Rengarajan Baskaran, Pasupathi Sundaramoorthy & Bong Kyu Yoo. (2014) Enhanced skin permeation of 5α-reductase inhibitors entrapped into surface-modified liquid crystalline nanoparticles. Archives of Pharmacal Research 38:4, pages 534-542.
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Abdulmaged M. TraishAshwini MulgaonkarNicholas Giordano. (2014) The Dark Side of 5α-Reductase Inhibitors' Therapy: Sexual Dysfunction, High Gleason Grade Prostate Cancer and Depression. Korean Journal of Urology 55:6, pages 367.
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