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Drug Safety Evaluations

Axitinib safety in metastatic renal cell carcinoma: suggestions for daily clinical practice based on case studies

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Vivek Narayan & Naomi Balzer Haas. (2016) Axitinib in the treatment of renal cell carcinoma: patient selection and perspectives. International Journal of Nephrology and Renovascular Disease 9, pages 65-72.
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Kashif Haider, Shivani Sharma, Yuba Raj Pokharel, Subham Das, Alex Joseph, Abul Kalam Najmi, Faiz Ahmad & Mohammad Shahar Yar. (2022) Synthesis, biological evaluation, and in silico studies of indole‐tethered pyrazoline derivatives as anticancer agents targeting topoisomerase IIα. Drug Development Research 83:7, pages 1555-1577.
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Bieke Van der Veken, Guido R.Y. De Meyer & Wim Martinet. (2018) Axitinib attenuates intraplaque angiogenesis, haemorrhages and plaque destabilization in mice. Vascular Pharmacology 100, pages 34-40.
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Senji Hoshi, Kenji Numahata, Hidenori Kanno, Masahiko Sato, Akihito Kuromoto, Kunihisa Nezu, Takanari Sakai, Chihito Konno, Yuichi Ishizuka, Hideaki Izumi, Katsuyuki Taguchi, Kunio Ono, Kiyotsugu Hoshi, Satoshi Kanto, Rika Takahashi, Bilim Vladimir, Naoe Akimoto, Isoji Sasagawa & Shoichiro Ohta. (2017) Updated recommendation on molecular-targeted therapy for metastatic renal cell cancer. Molecular and Clinical Oncology 7:4, pages 591-594.
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Giuseppe Tridente. 2017. Adverse Events and Oncotargeted Kinase Inhibitors. Adverse Events and Oncotargeted Kinase Inhibitors 395 414 .
M S Zabriskie, C A Eide, D Yan, N A Vellore, A D Pomicter, S L Savage, B J Druker, M W Deininger & T O'Hare. (2015) Extreme mutational selectivity of axitinib limits its potential use as a targeted therapeutic for BCR-ABL1-positive leukemia. Leukemia 30:6, pages 1418-1421.
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Chiara Ciccarese, Alessandra Modena, Giampaolo Tortora & Francesco Massari. (2015) Kidney cancer and 2014: is innovation really over?. Future Oncology 11:9, pages 1437-1449.
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Tea Pemovska, Eric Johnson, Mika Kontro, Gretchen A. Repasky, Jeffrey Chen, Peter Wells, Ciarán N. Cronin, Michele McTigue, Olli Kallioniemi, Kimmo Porkka, Brion W. Murray & Krister Wennerberg. (2015) Axitinib effectively inhibits BCR-ABL1(T315I) with a distinct binding conformation. Nature 519:7541, pages 102-105.
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Gilda G. Hillman, Fulvio Lonardo, David J. Hoogstra, Joseph Rakowski, Christopher K. Yunker, Michael C. Joiner, Gregory Dyson, Shirish Gadgeel & Vinita Singh-Gupta. (2014) Axitinib Improves Radiotherapy in Murine Xenograft Lung Tumors. Translational Oncology 7:3, pages 400-409.
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