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Safety of carbonic anhydrase inhibitors

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Romeo Romagnoli, Tiziano De Ventura, Stefano Manfredini, Erika Baldini, Claudiu T. Supuran, Alessio Nocentini, Andrea Brancale, Roberta Bortolozzi, Lorenzo Manfreda & Giampietro Viola. (2023) Design, synthesis, and biological investigation of selective human carbonic anhydrase II, IX, and XII inhibitors using 7-aryl/heteroaryl triazolopyrimidines bearing a sulfanilamide scaffold. Journal of Enzyme Inhibition and Medicinal Chemistry 38:1.
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Ejaife O. Agbani, Xiaojuan Zhao, Christopher M. Williams, Riyaad Aungraheeta, Ingeborg Hers, Erik R. Swenson & Alastair W. Poole. (2020) Carbonic Anhydrase Inhibitors suppress platelet procoagulant responses and in vivo thrombosis. Platelets 31:7, pages 853-859.
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Joyanta K. Modak, Alexandra Tikhomirova, Rebecca J. Gorrell, Mohammad M. Rahman, Despina Kotsanas, Tony M. Korman, Jose Garcia-Bustos, Terry Kwok, Richard L. Ferrero, Claudiu T. Supuran & Anna Roujeinikova. (2019) Anti-Helicobacter pylori activity of ethoxzolamide. Journal of Enzyme Inhibition and Medicinal Chemistry 34:1, pages 1660-1667.
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Claudiu T. Supuran. (2016) Drug interaction considerations in the therapeutic use of carbonic anhydrase inhibitors. Expert Opinion on Drug Metabolism & Toxicology 12:4, pages 423-431.
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Alexandre Le Darz, Agnès Mingot, Fodil Bouazza, Ugo Castelli, Omar Karam, Muhammet Tanc, Claudiu T. Supuran & Sébastien Thibaudeau. (2015) Fluorinated pyrrolidines and piperidines incorporating tertiary benzenesulfonamide moieties are selective carbonic anhydrase II inhibitors. Journal of Enzyme Inhibition and Medicinal Chemistry 30:5, pages 737-745.
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Claudiu T Supuran. (2015) Acetazolamide for the treatment of idiopathic intracranial hypertension. Expert Review of Neurotherapeutics 15:8, pages 851-856.
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Ahmed M. Alafeefy, Hatem A. Abdel-Aziz, F. Carta, Claudiu T. Supuran, Shilendra K. Pathak, Onkar Prasad & Leena Sinha. (2015) Exploring QSARs of some benzenesulfonamides incorporating cyanoacrylamide moieties as a carbonic anhydrase inhibitors (specifically against tumor-associated isoforms IX and XII). Journal of Enzyme Inhibition and Medicinal Chemistry 30:4, pages 519-523.
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Articles from other publishers (36)

Amanda D. Henderson, Claudia M. Prospero Ponce, Andrew G. Lee & Gregory P. Van Stavern. (2023) Should Routine Complete Blood Count and Electrolytes Be Sent as Part of the Initial Diagnostic Workup for Idiopathic Intracranial Hypertension?. Journal of Neuro-Ophthalmology 43:4, pages 569-574.
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Suleyman Akocak, Nebih Lolak, Hatice Esra Duran, Mesut Işık, Cüneyt Türkeş, Mustafa Durgun & Şükrü Beydemir. (2023) Synthesis and Characterization of Novel 1,3‐Diaryltriazene‐Substituted Sulfaguanidine Derivatives as Selective Carbonic Anhydrase Inhibitors: Biological Evaluation, in Silico ADME/T and Molecular Docking Study . Chemistry & Biodiversity 20:8.
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Sarah F. Sanghavi & Erik R. Swenson. (2023) Arterial Blood Gases and Acid-Base Regulation. Seminars in Respiratory and Critical Care Medicine.
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David HillebrandtAnil GurtooThomas KupperPaul RichardsVolker SchöfflPankaj ShahRianne van der SpekNikki WallisJim Milledge. (2023) UIAA Medical Commission Recommendations for Mountaineers, Hillwalkers, Trekkers, and Rock and Ice Climbers with Diabetes. High Altitude Medicine & Biology 24:2, pages 110-126.
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Ejaife O. Agbani, Ingeborg Hers & Alastair W. Poole. (2023) Platelet procoagulant membrane dynamics: a key distinction between thrombosis and hemostasis?. Blood Advances 7:8, pages 1615-1619.
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Rebecca Strawbridge, Nefize Yalin, Stelios Orfanos & Allan H. Young. (2023) Acetazolamide for Bipolar Disorders: A Scoping Review. Brain Sciences 13:1, pages 140.
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Giulia Culletta, Marco Tutone, Maria Zappalà & Anna Maria Almerico. (2023) Sulfonamide Moiety as “Molecular Chimera” in the Design of New Drugs. Current Medicinal Chemistry 30:2, pages 128-163.
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Cem Yamali, Hiroshi Sakagami, Keitaro Satoh, Kenjiro Bandow, Yoshihiro Uesawa, Silvia Bua, Andrea Angeli, Claudiu T. Supuran & Halise Inci Gul. (2022) Investigation of carbonic anhydrase inhibitory effects and cytotoxicities of pyrazole-based hybrids carrying hydrazone and zinc-binding benzenesulfonamide pharmacophores. Bioorganic Chemistry 127, pages 105969.
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Marko M. Popovic, Matthew B. Schlenker, Deva Thiruchelvam & Donald A. Redelmeier. (2022) Serious Adverse Events of Oral and Topical Carbonic Anhydrase Inhibitors. JAMA Ophthalmology 140:3, pages 235.
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Rachel D. Heisler, Jordan J. Kelly, Sara Abedinzadegan Abdi, Jennifer L. Hawker, Leanne G. Fong, Janet L. Quon, Josee Z. Rioux & Jennifer C. Jupp. (2021) Evaluation of an oral sodium bicarbonate protocol for high-dose methotrexate urine alkalinization. Supportive Care in Cancer 30:2, pages 1273-1281.
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Alokesh Ganguly, KomalDaljit Singh & Mainak Chakraborty. (2022) Dorzolamide-induced giant cell thrombocytopenia: A case report of a hitherto unreported condition. Indian Journal of Ophthalmology - Case Reports 2:3, pages 682.
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Ce Dong, Xiongfei Yue, Lin Zhu, Pengzhen Ge, Guozhen Zheng, Zhanying Ye & Baogen Pan. (2022) Curcumin Attenuates Hydrocephalus via Activation of E2F Transcription Factor 4. Cerebrovascular Diseases 51:5, pages 678-685.
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Megha A. Nimje, Himadri Patir, Rajeshkumar Tirpude & Bhuvnesh Kumar. (2022) Elucidating the combined effect of intermittent hypoxia training and acetazolamide on hypoxia induced hematological and physiological changes. Current Research in Physiology 5, pages 327-337.
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Sook-Ha Fan, Elisa Liberini & Friedrich Götz. (2021) Staphylococcus aureus Genomes Harbor Only MpsAB-Like Bicarbonate Transporter but Not Carbonic Anhydrase as Dissolved Inorganic Carbon Supply System. Microbiology Spectrum 9:3.
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Mikias Mered Tilahun, Betelhem Temesgen Yibekal, Habtamu Kerebih & Fisseha Ademassu Ayele. (2021) Prevalence of common mental disorders and associated factors among adults with Glaucoma attending University of Gondar comprehensive specialized hospital tertiary eye care and training center, Northwest, Ethiopia 2020. PLOS ONE 16:5, pages e0252064.
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Erik R. Swenson, Akshay Kumar, Nimisha Kumar & Bernardo V. Alvarez. 2021. The Carbonic Anhydrases: Current and Emerging Therapeutic Targets. The Carbonic Anhydrases: Current and Emerging Therapeutic Targets 37 77 .
Aidan J. Hampson, Jennifer R. Schroeder, Kayla N. Ellefsen, Luba Yammine, David H. Epstein, Kenzie L. Preston, Marilyn A. Huestis & Christopher D. Verrico. (2020) Subtherapeutic Acetazolamide Doses as a Noninvasive Method for Assessing Medication Adherence. Clinical Pharmacology & Therapeutics 108:6, pages 1203-1212.
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Muhammad Sona Khan, Wulfran Trenet, Nancy Xing, Britta Sibley, Muzaffar Abbas, Mariya al-Rashida, Khalid Rauf & Chitra D. Mandyam. (2020) A Novel Sulfonamide, 4-FS, Reduces Ethanol Drinking and Physical Withdrawal Associated With Ethanol Dependence. International Journal of Molecular Sciences 21:12, pages 4411.
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Isabel AlgazeLara PhillipsPeter InglisGabriel LathropJaclyn GadboisKatherine RizzoloN. Stuart Harris. (2020) Incidence of Mild Cognitive Impairment with Ascending Altitude. High Altitude Medicine & Biology 21:2, pages 184-191.
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Christopher N Schmickl, Robert L Owens, Jeremy E Orr, Bradley A Edwards & Atul Malhotra. (2020) Side effects of acetazolamide: a systematic review and meta-analysis assessing overall risk and dose dependence. BMJ Open Respiratory Research 7:1, pages e000557.
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Bryan Strelow & David Fleischman. (2020) Glaucoma in pregnancy: an update. Current Opinion in Ophthalmology 31:2, pages 114-122.
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Sang Jun Park, Seong Jun Byun, Jae Yoon Park & Martha Kim. (2019) Primary Open-angle Glaucoma and Increased Risk of Chronic Kidney Disease. Journal of Glaucoma 28:12, pages 1067-1073.
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Cem Yamali, Halise Inci Gul, Abdulilah Ece, Silvia Bua, Andrea Angeli, Hiroshi Sakagami, Ertan Sahin & Claudiu T. Supuran. (2019) Synthesis, biological evaluation and in silico modelling studies of 1,3,5-trisubstituted pyrazoles carrying benzenesulfonamide as potential anticancer agents and selective cancer-associated hCA IX isoenzyme inhibitors. Bioorganic Chemistry 92, pages 103222.
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Begüm Nurpelin Sağlık, Ulviye Acar Çevik, Derya Osmaniye, Serkan Levent, Betul Kaya Çavuşoğlu, Yeliz Demir, Sinem Ilgın, Yusuf Özkay, Ali Savaş Koparal, Şükrü Beydemir & Zafer Asım Kaplancıklı. (2019) Synthesis, molecular docking analysis and carbonic anhydrase I-II inhibitory evaluation of new sulfonamide derivatives. Bioorganic Chemistry 91, pages 103153.
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Lina Baranauskienė & Daumantas Matulis. 2019. Carbonic Anhydrase as Drug Target. Carbonic Anhydrase as Drug Target 3 14 .
Fredric Cohen. (2019) Open-Label, Dose-Escalation, Phase 1 Study of Safety and Single and Multiple-Dose Pharmacokinetics of Dichlorphenamide in Healthy Volunteers. Clinical Pharmacology in Drug Development 8:1, pages 87-94.
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Erik R. Swenson. (2018) Does Aerobic Respiration Produce Carbon Dioxide or Hydrogen Ion and Bicarbonate?. Anesthesiology 128:5, pages 873-879.
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Iva Hoffmanová & Daniel Sánchez. (2018) Metabolic acidosis and anaemia associated with dorzolamide in a patient with impaired renal function. British Journal of Clinical Pharmacology 84:4, pages 796-799.
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Lara PhillipsBuddha BasnyatYuchiao ChangErik R. SwensonN. Stuart Harris. (2017) Findings of Cognitive Impairment at High Altitude: Relationships to Acetazolamide Use and Acute Mountain Sickness. High Altitude Medicine & Biology 18:2, pages 121-127.
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Lina Baranauskiene & Daumantas Matulis. (2017) Herbicide oryzalin inhibits human carbonic anhydrases in vitro . Journal of Biochemical and Molecular Toxicology 31:6, pages e21894.
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Enrico DoneganiPeter PaalThomas KüpperUrs HeftiBuddha BasnyatAnna CarcellerPierre BouzatRianne van der SpekDavid Hillebrandt. (2016) Drug Use and Misuse in the Mountains: A UIAA MedCom Consensus Guide for Medical Professionals. High Altitude Medicine & Biology 17:3, pages 157-184.
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Aidan J. HampsonShanna BabalonisMichelle R. LofwallPaul A. NuzzoPhillip KrieterSharon L. Walsh. (2016) A Pharmacokinetic Study Examining Acetazolamide as a Novel Adherence Marker for Clinical Trials. Journal of Clinical Psychopharmacology 36:4, pages 324-332.
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Danish Idrees, Sudhir Kumar, Syed Abdul Arif Rehman, Samudrala Gourinath, Asimul Islam, Faizan Ahmad & Md. Imtaiyaz Hassan. (2016) Cloning, expression, purification and characterization of human mitochondrial carbonic anhydrase VA. 3 Biotech 6:1.
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Per M. Nielsen & Angela Fago. (2015) Inhibitory effects of nitrite on the reactions of bovine carbonic anhydrase II with CO2 and bicarbonate consistent with zinc-bound nitrite. Journal of Inorganic Biochemistry 149, pages 6-11.
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Virginija Dudutienė, Jurgita Matulienė, Alexey Smirnov, David D. Timm, Asta Zubrienė, Lina Baranauskienė, Vaida Morku̅naitė, Joana Smirnovienė, Vilma Michailovienė, Vaida Juozapaitienė, Aurelija Mickevičiu̅tė, Justina Kazokaitė, Sandra Bakšytė, Aistė Kasiliauskaitė, Jelena Jachno, Jurgita Revuckienė, Miglė Kišonaitė, Vilma Pilipuitytė, Eglė Ivanauskaitė, Goda Milinavičiu̅tė, Vytautas Smirnovas, Vilma Petrikaitė, Visvaldas Kairys, Vytautas Petrauskas, Povilas Norvaišas, Darius Lingė, Paulius Gibieža, Edita Čapkauskaitė, Audrius Zakšauskas, Egidijus Kazlauskas, Elena Manakova, Saulius Gražulis, John E. Ladbury & Daumantas Matulis. (2014) Discovery and Characterization of Novel Selective Inhibitors of Carbonic Anhydrase IX. Journal of Medicinal Chemistry 57:22, pages 9435-9446.
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Erik R. Swenson. (2014) New Insights into Carbonic Anhydrase Inhibition, Vasodilation, and Treatment of Hypertensive-Related Diseases. Current Hypertension Reports 16:9.
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