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Expert Opinion on Drug Safety Volume 13, 2014 - Issue 7
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The problem of osteoporosis in epileptic patients taking antiepileptic drugs

Barbara MiziakMedical University, Department of Pathophysiology, Jaczewskiego 8, PL 20-090 Lublin, Poland
,
Barbara BłaszczykFaculty of Health Sciences, High School of Economics, Law and Medical Sciences, Jagiellonska 109 A, PL 25-734 Kielce, Poland
,
Magdalena Chrościńska-KrawczykMedical University of Lublin, Department of Pediatrics, Endocrinology and Neurology, Chodzki 2, PL 20-093 Lublin, Poland
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Grzegorz DanilkiewiczMedical University, Department of Pathophysiology, Jaczewskiego 8, PL 20-090 Lublin, Poland
,
Ewa Jagiełło-WójtowiczMedical University of Lublin, Department of Toxicology, Chodzki 8, 20-093 Lublin, Poland
&
Stanisław J CzuczwarMedical University, Department of Pathophysiology, Jaczewskiego 8, PL 20-090 Lublin, Poland;Institute of Rural Health, Department of Physiopathology, Jaczewskiego 2, PL 20-092 Lublin, Poland+48 81 718 7365; +48 81 718 7364; [email protected]
Pages 935-946 | Published online: 12 May 2014

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Barbara Miziak, Magdalena Chrościńska-Krawczyk & Stanisław J Czuczwar. (2019) An update on the problem of osteoporosis in people with epilepsy taking antiepileptic drugs. Expert Opinion on Drug Safety 18:8, pages 679-689.
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Monika Banach, Barbara Miziak, Kinga K. Borowicz-Reutt & Stanisław J. Czuczwar. (2019) Advances with extended and controlled release formulations of antiepileptics in the elderly. Expert Opinion on Pharmacotherapy 20:3, pages 333-341.
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Monika Banach, Monika Popławska, Barbara Błaszczyk, Kinga K. Borowicz & Stanisław J. Czuczwar. (2016) Pharmacokinetic/pharmacodynamic considerations for epilepsy – depression comorbidities. Expert Opinion on Drug Metabolism & Toxicology 12:9, pages 1067-1080.
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Krzysztof Łukawski, Paweł Gryta, Jarogniew Łuszczki & Stanisław J. Czuczwar. (2016) Exploring the latest avenues for antiepileptic drug discovery and development. Expert Opinion on Drug Discovery 11:4, pages 369-382.
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Articles from other publishers (29)

Sterling J. DeShazo, Garett L. Ozmer, Kyle A. Horton & William M. Weiss. (2023) Phenytoin is associated with increased risk of osteoporosis and fragility fractures in adult epileptic patients. Journal of Bone and Mineral Metabolism.
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Jordan D. Ross & Alicia Diaz-Thomas. (2023) Perioperative Evaluation and Management of Children with Osteoporosis and Low Bone Mineral Density. Orthopedic Clinics of North America.
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Huan Wang, Ziye Liu, Dawei Niu, Haobo Li, Yaguang Han, Jinhui Peng & Qirong Qian. (2023) Carbamazepine regulates USP10 through miR-20a-5p to affect the deubiquitination of SKP2 and inhibit osteogenic differentiation. Journal of Orthopaedic Surgery and Research 18:1.
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Iva Karesova, Julius Simko, Sona Fekete, Eva Zimcikova, Jana Malakova, Helena Zivna, Ladislava Pavlikova & Vladimir Palicka. (2023) The Effect of Zonisamide on Rat Bone Mass, Structure, and Metabolism. Pharmacology 108:4, pages 359-367.
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Yang Li, Ruotian Zhang, Maoxian Ren, Hedong Liu & Min Yang. (2022) Experimental study on the effects of simvastatin in reversing the femoral metaphyseal defects induced by sodium valproate in normal and ovariectomized rats. Heliyon 8:9, pages e10480.
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Ruotian Zhang, Min Yang, Yang Li, Hedong Liu, Maoxian Ren & Zhou-Shan Tao. (2021) Effect of alendronate on the femoral metaphyseal defect under carbamazepine in ovariectomized rats. Journal of Orthopaedic Surgery and Research 16:1.
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Miguel E. Habeych, Tatiana Falcone, Anjali Dagar, Lisa Ford & Ruby Castilla-Puentes. (2021) Dementia, Subtype of Seizures, and the Risk of New Onset Seizures: A Cohort Study. Journal of Alzheimer's Disease 81:3, pages 973-980.
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Paul Boon, Susana Ferrao Santos, Anna C. Jansen, Lieven Lagae, Benjamin Legros & Sarah Weckhuysen. (2020) Recommendations for the treatment of epilepsy in adult and pediatric patients in Belgium: 2020 update. Acta Neurologica Belgica 121:1, pages 241-257.
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Nelson B. Watts. 2021. Marcus and Feldman's Osteoporosis. Marcus and Feldman's Osteoporosis 1061 1068 .
Xinyue Zhang, Rui Zhong, Qingling Chen, Mengmeng Li, Weihong Lin & Li Cui. (2020) Effect of carbamazepine on the bone health of people with epilepsy: a systematic review and meta-analysis. Journal of International Medical Research 48:3, pages 030006052090260.
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Fawzy Ali Saad. (2019) Novel insights into the complex architecture of osteoporosis molecular genetics. Annals of the New York Academy of Sciences 1462:1, pages 37-52.
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Eswar K. Aratikatla & Asish K. Bhattacharya. (2019) A Short Review of Synthetic Routes for the Antiepileptic Drug ( R )-Lacosamide . Organic Process Research & Development 24:1, pages 17-24.
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Barbara Błaszczyk, Aleksandra Walczak, Natalia Ścirka, Agnieszka Konarzewska, Barbara Miziak & Stanisław J. Czuczwar. (2020) Pharmacological and non-pharmacological approaches to life threatening conditions in epilepsy. Journal of Epileptology 28, pages 43-54.
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Mohammed Sadiq, Vikrant Kulkarni, Syed Azher Hussain, Mohammed Ismail & Mayur Nayak. (2019) Low-velocity simultaneous bilateral femoral neck fracture following long-term antiepileptic therapy: A case report. World Journal of Orthopedics 10:10, pages 371-377.
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Mohammed Sadiq, Vikrant Kulkarni, Syed Azher Hussain, Mohammed Ismail & Mayur Nayak. (2019) Low-velocity simultaneous bilateral femoral neck fracture following long-term antiepileptic therapy: A case report. World Journal of Orthopedics 10:10, pages 363-369.
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Bushra Parveen, Ambrish Kumar Tiwari, Moon Jain, Subhashis Pal, Naibedya Chattopadhyay, Manjari Tripathi & Divya Vohora. (2018) The anti-epileptic drugs valproate, carbamazepine and levetiracetam cause bone loss and modulate Wnt inhibitors in normal and ovariectomised rats. Bone 113, pages 57-67.
Crossref
Haya Fernandez, Heba Tallah Mohammed & Tejal Patel. (2018) Vitamin D supplementation for bone health in adults with epilepsy: A systematic review. Epilepsia 59:4, pages 885-896.
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Miyako Suzuki, Magali Millecamps, Lina Naso, Seiji Ohtori, Chisato Mori & Laura S. Stone. (2017) Chronic Osteoporotic Pain in Mice: Cutaneous and Deep Musculoskeletal Pain Are Partially Independent of Bone Resorption and Differentially Sensitive to Pharmacological Interventions. Journal of Osteoporosis 2017, pages 1-15.
Crossref
Hueng-Chuen Fan, Herng-Shen Lee, Kai-Ping Chang, Yi-Yen Lee, Hsin-Chuan Lai, Pi-Lien Hung, Hsiu-Fen Lee & Ching-Shiang Chi. (2016) The Impact of Anti-Epileptic Drugs on Growth and Bone Metabolism. International Journal of Molecular Sciences 17:8, pages 1242.
Crossref
Sandra J. Petty, Helen Wilding & John D. Wark. (2016) Osteoporosis Associated with Epilepsy and the Use of Anti-Epileptics—a Review. Current Osteoporosis Reports 14:2, pages 54-65.
Crossref
Duygu Aksoy, Bet?l Tekin G?veli, Pelin Do?an Ak, H?seyin Sar?, Dilek Atakl? & Baki Arpac?. (2016) Effects of Oxcarbazepine and Levetiracetam on Calcium, Ionized Calcium, and 25-OH Vitamin-D3 Levels in Patients with Epilepsy. Clinical Psychopharmacology and Neuroscience 14:1, pages 74-78.
Crossref
Hiba Arif Haider & Lawrence J. Hirsch. 2015. The Treatment of Epilepsy. The Treatment of Epilepsy 205 220 .
Eswar K. Aratikatla & Asish K. Bhattacharya. (2015) Chiral pool approach for the synthesis of functionalized amino acids: synthesis of antiepileptic drug ( R )-lacosamide. Tetrahedron Letters 56:42, pages 5802-5803.
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Alexander S. Bryson & Patrick W. Carney. (2015) Pharmacotherapy for epilepsy in the elderly. Journal of Pharmacy Practice and Research 45:3, pages 349-356.
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Sofia Markoula, Chrissa Sioka, Thomas Exarchopoulos, Dimitrios Chatzistefanidis, John Kalef-Ezra, Andreas Fotopoulos & Athanassios P. Kyritsis. (2015) Gender specific association of decreased bone mineral density in patients with epilepsy. Neurologia i Neurochirurgia Polska 49:4, pages 267-271.
Crossref
Yuvraj Garg & Satyendra Kumar Pandey. (2015) An Enantioselective Approach to Functionalized Amino Acids: Total Synthesis of Antiepileptic Drug ( R )-Lacosamide . The Journal of Organic Chemistry 80:8, pages 4201-4203.
Crossref
Jose de Leon. (2015) The effects of antiepileptic inducers in neuropsychopharmacology, a neglected issue. Part I: A summary of the current state for clinicians. Revista de Psiquiatría y Salud Mental (English Edition) 8:2, pages 97-115.
Crossref
Jose de Leon. (2015) Efectos de los inductores antiepil?pticos en la neuropsicofarmacolog?a: una cuesti?n ignorada. Parte I: Resumen para los cl?nicos de la situaci?n actual. Revista de Psiquiatr?a y Salud Mental 8:2, pages 97-115.
Crossref
Yang Li, Ruotian Zhang, Maoxian Ren & Min Yang. (2022) Experimental Study on the Effects of Simvastatin in Reversing the Femoral Metaphyseal Defects Induced by Sodium Valproate in Normal and Ovariectomized Rats. SSRN Electronic Journal.
Crossref

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