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Expert Opinion on Drug Safety Volume 14, 2015 - Issue 7
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Review

Management of glucocorticoid-induced osteoporosis: clinical data in relation to disease demographics, bone mineral density and fracture risk

Eustathios KenanidisAristotle University Medical School, Academic Orthopaedic Unit, Thessaloniki, Greece
, MD PhD (Consultant Orthopaedic Surgeon) ,
Michael E PotoupnisAristotle University Medical School, Academic Orthopaedic Unit, Thessaloniki, Greece;Aristotle University Medical School, Academic Orthopaedic Unit, Thessaloniki, Greece
, MD PhD (Consultant Orthopaedic Surgeon) (Assistant Professor of Orthopaedic,) (Consultant Orthopaedic Surgeon) (Assistant Professor of Orthopaedic,) ,
Panagiotis KakoulidisAristotle University Medical School, Academic Orthopaedic Unit, Thessaloniki, Greece
, MD (Resident in Orthopaedics) ,
Andreas LeonidouAristotle University Medical School, Academic Orthopaedic Unit, Thessaloniki, Greece
, MD MSc MRCS (Senior Registrar in Orthopaedics) ,
Grigorios T SakellariouAristotle University Medical School, Academic Orthopaedic Unit, Thessaloniki, Greece
, MD (Associate Professor of Orthopaedic Surgery) ,
Fares E SayeghAristotle University Medical School, Academic Orthopaedic Unit, Thessaloniki, Greece
, MD (Consultant Rheumatologist) &
Eleftherios TsiridisAristotle University Medical School, Academic Orthopaedic Unit, Thessaloniki, [email protected]
, MD MSc PhD(Lond.) FRCS (Associate Professor of Orthopaedics, Secretary General European Hip Society) show all
Pages 1035-1053 | Published online: 08 May 2015

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Huixia Li, Danhui Li, Zhengmin Ma, Zhuang Qian, Xiaomin Kang, Xinxin Jin, Fang Li, Xinluan Wang, Qian Chen, Hongzhi Sun & Shufang Wu. (2018) Defective autophagy in osteoblasts induces endoplasmic reticulum stress and causes remarkable bone loss. Autophagy 14:10, pages 1726-1741.
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Articles from other publishers (14)

Nazarena Betella & Miriam Cellini. (2022) Terapia di prima linea dell’osteoporosi indotta da glucocorticoidi. L'Endocrinologo 23:1, pages 95-97.
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Li Lu, Yanzhen Cai, Xiaoling Luo, Zhangting Wang, Sin Hang Fung, Huanhuan Jia, Chi Lam Yu, Wai Yee Chan, Kai Kei Miu & Wende Xiao. (2021) A Core Omnigenic Non-coding Trait Governing Dex-Induced Osteoporotic Effects Identified Without DEXA. Frontiers in Pharmacology 12.
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Congshan Li, Panpan Yang, Bo Liu, Jie Bu, Hongrui Liu, Jie Guo, Tomoka Hasegawa, Haipeng Si & Minqi Li. (2021) Prednisolone induces osteocytes apoptosis by promoting Notum expression and inhibiting PI3K/AKT/GSK3β/β-catenin pathway. Journal of Molecular Histology 52:5, pages 1081-1095.
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梦馨 杨. (2021) Research Progress of Autophagy in the Mechanism of Periodontal Disease. Advances in Clinical Medicine 11:02, pages 567-574.
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Tiantian Wang, Xiaonan Liu & Chengqi He. (2020) Glucocorticoid-induced autophagy and apoptosis in bone. Apoptosis 25:3-4, pages 157-168.
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Zinan Qin, Siyu Li, Xiaojuan Zhang, Guoxiu Liu, Min Gu, Nan Zhang, Jiao Liu, Zhihong Ji, Keao Li, Yongpeng Han & Huaqiang Zhai. (2020) Combination Therapy of Wuweizi ( Schisandrae Chinensis Fructus ) and Dexamethasone Alleviated Dexamethasone-Induced Glucocorticoid Osteoporosis in Rats with Idiopathic Pulmonary Fibrosis . BioMed Research International 2020, pages 1-9.
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Jiancheng Yang, Jingbao Li, Xiaobin Cui, Wenbin Li, Yanru Xue, Peng Shang & Hao Zhang. (2020) Blocking glucocorticoid signaling in osteoblasts and osteocytes prevents mechanical unloading-induced cortical bone loss. Bone 130, pages 115108.
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Yong‑Xin Hu, Ren‑Dong Zheng, Yao‑Fu Fan, Li Sun, Xin Hu & Chao Liu. (2019) The effects of bone metabolism in different methylprednisolone pulse treatments for Graves' ophthalmopathy. Experimental and Therapeutic Medicine.
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Chenguang Wang, Xin Wan, Yun Li, Huafeng Zhang & Lei Zhang. (2018) Morin protects glucocorticoid-induced osteoporosis through regulating the mitogen-activated protein kinase signaling pathway. Journal of Natural Medicines 72:4, pages 929-936.
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Lihua Han, Xiangzhao Mao, Kai Wang, Yuanyuan Li, Meihui Zhao, Jingfeng Wang & Changhu Xue. (2018) Phosphorylated peptides from Antarctic krill (Euphausia superba) ameliorated osteoporosis by activation of osteogenesis-related MAPKs and PI3K/AKT/GSK-3β pathways in dexamethasone-treated mice. Journal of Functional Foods 47, pages 447-456.
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Wanlin Liu, Zhenqun Zhao, Yuyan Na, Chenyang Meng, Jianzhong Wang & Rui Bai. (2018) Dexamethasone-induced production of reactive oxygen species promotes apoptosis via endoplasmic reticulum stress and autophagy in MC3T3-E1 cells. International Journal of Molecular Medicine.
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Shaokun Zhang, Yongyi Liu & Qingwei Liang. (2018) Low-dose dexamethasone affects osteoblast viability by inducing autophagy via intracellular ROS. Molecular Medicine Reports.
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Jasmina MilovanovićR.R.. (2018) Prevention and treatment of glucocorticoid-induced osteoporosis. Racionalna terapija 10:2, pages 33-41.
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Laurianne Imbert & Adele Boskey. (2016) Effects of Drugs on Bone Quality. Clinical Reviews in Bone and Mineral Metabolism 14:3, pages 167-196.
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