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Drug Safety Evaluation

Safety considerations with fenofibrate/simvastatin combination

& , MD FRSH FASA FISA (Professor of Medicine)

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Nicola Tarantino, Francesco Santoro, Luisa De Gennaro, Michele Correale, Francesca Guastafierro, Antonio Gaglione, Matteo Di Biase & Natale Daniele Brunetti. (2017) Fenofibrate/simvastatin fixed-dose combination in the treatment of mixed dyslipidemia: safety, efficacy, and place in therapy. Vascular Health and Risk Management 13, pages 29-41.
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Theodosios Filippatos, Eleftheria Tzavella, Christos Rizos, Moses Elisaf & George Liamis. (2017) Acid-base and electrolyte disorders associated with the use of antidiabetic drugs. Expert Opinion on Drug Safety 16:10, pages 1121-1132.
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Nicola Ferri, Alberto Corsini, Cesare Sirtori & Massimiliano Ruscica. (2017) PPAR-α agonists are still on the rise: an update on clinical and experimental findings. Expert Opinion on Investigational Drugs 26:5, pages 593-602.
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T. D. Filippatos, M. Florentin, M. Georgoula & M. S. Elisaf. (2017) Pharmacological management of diabetic dyslipidemia. Expert Review of Clinical Pharmacology 10:2, pages 187-200.
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T. D. Filippatos, E. Klouras, F. Barkas & M. Elisaf. (2016) Cholesteryl ester transfer protein inhibitors: challenges and perspectives. Expert Review of Cardiovascular Therapy 14:8, pages 953-962.
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T. D. Filippatos & M. S. Elisaf. (2016) Pitavastatin and carbohydrate metabolism: what is the evidence?. Expert Review of Clinical Pharmacology 9:7, pages 955-960.
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Anastazia A. Kei, Theodosios D. Filippatos & Moses S. Elisaf. (2016) The safety of ezetimibe and simvastatin combination for the treatment of hypercholesterolemia. Expert Opinion on Drug Safety 15:4, pages 559-569.
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Articles from other publishers (10)

Alan Chait. (2023) Multifactorial chylomicronemia syndrome. Current Opinion in Endocrinology, Diabetes & Obesity.
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Agata Górniak, Hanna Czapor-Irzabek, Adrianna Złocińska, Agnieszka Gawin-Mikołajewicz & Bożena Karolewicz. (2023) Screening of Fenofibrate-Simvastatin Solid Dispersions in the Development of Fixed-Dose Formulations for the Treatment of Lipid Disorders. Pharmaceutics 15:2, pages 603.
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Myung Soo Park, Jong-Chan Youn, Eung Ju Kim, Ki Hoon Han, Sang Hak Lee, Sung Hea Kim, Byung Jin Kim, Sung Uk Kwon & Kyu-Hyung Ryu. (2021) Efficacy and Safety of Fenofibrate-Statin Combination Therapy in Patients With Inadequately Controlled Triglyceride Levels Despite Previous Statin Monotherapy: A Multicenter, Randomized, Double-blind, Phase IV Study. Clinical Therapeutics 43:10, pages 1735-1747.
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Alan ChaitRobert H. Eckel. (2019) The Chylomicronemia Syndrome Is Most Often Multifactorial. Annals of Internal Medicine 170:9, pages 626.
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Guido Filler & Ravneet NagraGuido Filler & Ravneet Nagra. 2019. Becoming a Successful Scholar. Becoming a Successful Scholar 13 22 .
Guido Filler, Sepideh Taheri, Christopher McIntyre, Connor Smith, Lakshmimathy Subramanian, Gerhard Fusch & Christoph Fusch. (2018) Chronic kidney disease stage affects small, dense low-density lipoprotein but not glycated low-density lipoprotein in younger chronic kidney disease patients: a cross-sectional study. Clinical Kidney Journal 11:3, pages 383-388.
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Jonathan N. Johnson & Guido Filler. (2018) The importance of cardiovascular disease in pediatric transplantation and its link to the kidneys. Pediatric Transplantation 22:3, pages e13146.
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Hongliang Li, Sung Eun Shin, Mi Seon Seo, Jin Ryeol An, Won-Kyo Jung, Kwon-Soo Ha, Eun-Taek Han, Seok-Ho Hong, Hyoweon Bang, Young Min Bae, Amy L. Firth, Il-Whan Choi & Won Sun Park. (2017) The PPARα activator fenofibrate inhibits voltage-dependent K+ channels in rabbit coronary arterial smooth muscle cells. European Journal of Pharmacology 812, pages 155-162.
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Lu Han, Wen-Jun Shen, Stefanie Bittner, Fredric B Kraemer & Salman Azhar. (2017) PPARs: regulators of metabolism and as therapeutic targets in cardiovascular disease. Part I: PPAR-α. Future Cardiology 13:3, pages 259-278.
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Xin Sun, Yan Zhang & Meilin Xie. (2017) The role of peroxisome proliferator-activated receptor in the treatment of non-alcoholic fatty liver disease. Acta Pharmaceutica 67:1, pages 1-13.
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