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Editorial

Implications of statin adverse effects in the elderly

Pages 389-397 | Published online: 10 May 2005

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (3)

Nadine E Stephenson & Simon F Crowe. (2016) Statin Use, Ageing, and Cognition: A Review. Australian Psychologist 51:3, pages 188-205.
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Ian Hamilton-Craig, David Colquhoun, Karam Kostner, Stan Woodhouse & Michael d’Emden. (2015) Lipid-modifying therapy in the elderly. Vascular Health and Risk Management 11, pages 251-263.
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Chiara Pavanello & Giuliana Mombelli. (2015) Considering gender in prescribing statins: what do physicians need to know?. Clinical Lipidology 10:6, pages 499-512.
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Articles from other publishers (23)

Fabrice Bonnet, Antoine Bénard, Pierre Poulizac, Mélanie Afonso, Aline Maillard, Francesco Salvo, Driss Berdaï, Nathalie Salles, Nicolas Rousselot, Sébastien Marchi, Nathalie Hayes & Jean-Philippe Joseph. (2020) Discontinuing statins or not in the elderly? Study protocol for a randomized controlled trial. Trials 21:1.
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Giovanni ViscogliosiChiara DonfrancescoCinzia Lo NoceDiego VanuzzoFlavia CarleSimona GiampaoliLuigi Palmieri. (2020) Prevalence and Correlates of Statin Underuse for Secondary Prevention of Cardiovascular Disease in Older Adults 65–79 Years of Age: The Italian Health Examination Survey 2008–2012. Rejuvenation Research 23:5, pages 394-400.
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Allyson M. Schweitzer, Molly A. Gingrich, Thomas J. Hawke & Irena A. Rebalka. (2020) The impact of statins on physical activity and exercise capacity: an overview of the evidence, mechanisms, and recommendations. European Journal of Applied Physiology 120:6, pages 1205-1225.
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Zhen Zhou, Loai Albarqouni, Andrea J. Curtis, Monique Breslin & Mark Nelson. (2020) The Safety and Tolerability of Statin Therapy in Primary Prevention in Older Adults: A Systematic Review and Meta-analysis. Drugs & Aging 37:3, pages 175-185.
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Xiaoming Jia, Mahmoud Al Rifai, Yochai Birnbaum, Sidney C. SmithJrJr & Salim S. Virani. (2019) The 2018 Cholesterol Management Guidelines: Topics in Secondary ASCVD Prevention Clinicians Need to Know. Current Atherosclerosis Reports 21:6.
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P. S. Nishtala, D. Gnjidic, T. Chyou & S. N. Hilmer. (2016) Discontinuation of statins in a population of older New Zealanders with limited life expectancy. Internal Medicine Journal 46:4, pages 493-496.
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Jean-Philippe Joseph, Mélanie Afonso, Driss Berdaï, Nathalie Salles, Antoine Bénard, Bernard Gay & Fabrice Bonnet. (2015) Bénéfices et risques des statines en prévention primaire chez la personne âgée. La Presse Médicale 44:12, pages 1219-1225.
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Christian Constance, Ori Ben-Yehuda, Nanette K Wenger, Franklin Zieve, Jianxin Lin, Mary E Hanson, Robert S Lowe & Andrew M Tershakovec. (2014) Atorvastatin 10 mg plus ezetimibe versus titration to atorvastatin 40 mg: attainment of European and Canadian guideline lipid targets in high-risk subjects ≥65 years. Lipids in Health and Disease 13:1.
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Cesare R. Sirtori. (2014) The pharmacology of statins. Pharmacological Research 88, pages 3-11.
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Samer Noaman, Joseph E. Ibrahim & Robert Grenfell. (2014) Prescribing Statins for Cardiovascular Disease Prevention in the Old: An Absence of Evidence and an Absence of Guidelines. Heart, Lung and Circulation 23:7, pages 619-624.
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Divey Manocha, Nidhi Bansal, Purva Gumaste & Sharon Brangman. (2013) Safety Profile of High-Dose Statin Therapy in Geriatric Patients with Stroke. Southern Medical Journal 106:12, pages 658-664.
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Helle Wallach Kildemoes, Mikkel Vass, Carsten Hendriksen & Morten Andersen. (2012) Statin utilization according to indication and age: A Danish cohort study on changing prescribing and purchasing behaviour. Health Policy 108:2-3, pages 216-227.
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Loukianos S. Rallidis, Katerina Fountoulaki & Maria Anastasiou-Nana. (2012) Managing the underestimated risk of statin-associated myopathy. International Journal of Cardiology 159:3, pages 169-176.
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Beatriz H. Caamaño, Jairo M. González Díaz, Daniel Guerrero Bracho, Harold Herrera & Manuel Castro Samur. (2012) Brote psicótico agudo y rabdomiólisis tras el uso de lovastatina. Revista Colombiana de Psiquiatría 41:3, pages 672-679.
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I. B. Zueva, K. I. Vanaeva & E. L. Sanez. (2012) The impact of simvastatin vs. atorvastatin on cognitive function in obese hypertensives. "Arterial’naya Gipertenziya" ("Arterial Hypertension") 18:3, pages 228-234.
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Matthew S. Murphy & Timothy O'Brien. 2009. Pharmacology and Therapeutics. Pharmacology and Therapeutics 303 320 .
Steven K. Baker & Imtiaz A. Samjoo. (2014) A Neuromuscular Approach to Statin-Related Myotoxicity. Canadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques 35:1, pages 8-21.
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Behzad Najafian, Donald B. Franklin & Agnes B. Fogo. (2007) Acute Renal Failure and Myalgia in a Transplant Patient. Journal of the American Society of Nephrology 18:11, pages 2870-2874.
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C. G. P. Roberts, E. Guallar & A. Rodriguez. (2007) Efficacy and Safety of Statin Monotherapy in Older Adults: A Meta-Analysis. The Journals of Gerontology Series A: Biological Sciences and Medical Sciences 62:8, pages 879-887.
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Joseph V. Agostini, Mary E. Tinetti, Ling Han, Gail McAvay, JoAnne M. Foody & John Concato. (2007) Effects of Statin Use on Muscle Strength, Cognition, and Depressive Symptoms in Older Adults. Journal of the American Geriatrics Society 55:3, pages 420-425.
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Prakash DeedwaniaPeter H. StoneC. Noel Bairey MerzJuan Cosin-AguilarNevres KoylanDon LuoPamela OuyangRyszard PiotrowiczKarin Schenck-GustafssonPhilippe SellierJames H. SteinPeter L. ThompsonDan Tzivoni. (2007) Effects of Intensive Versus Moderate Lipid-Lowering Therapy on Myocardial Ischemia in Older Patients With Coronary Heart Disease. Circulation 115:6, pages 700-707.
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Kenneth A. Antons, Craig D. Williams, Steven K. Baker & Paul S. Phillips. (2006) Clinical Perspectives of Statin-Induced Rhabdomyolysis. The American Journal of Medicine 119:5, pages 400-409.
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Harold Bays. (2006) Statin Safety: An Overview and Assessment of the Data—2005. The American Journal of Cardiology 97:8, pages S6-S26.
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