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Review

The side effects of the prostaglandin analogues

Pages 45-52 | Published online: 20 Dec 2006

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (28)

Doha Jbara, Maya Eiger-Moscovich, Elena Didkovsky, Yariv Keshet & Inbal Avisar. (2023) In Vivo Effects of Prostaglandin Analogues Application by Topical Drops or Retrobulbar Injections on the Orbital Fat of a Rat Model. Ocular Immunology and Inflammation 31:2, pages 298-303.
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Adam P. Deveau, Flávia Nagel da Silva, Thai Yen Ly & Ahsen Hussain. (2023) Periocular invasive melanoma manifestation in a patient using bimatoprost: case report and literature review. Orbit 42:1, pages 73-80.
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Andreas Katsanos, Ivano Riva, Banu Bozkurt, Gábor Holló, Luciano Quaranta, Francesco Oddone, Murat Irkec, Gordon N. Dutton & Anastasios G. Konstas. (2022) A new look at the safety and tolerability of prostaglandin analogue eyedrops in glaucoma and ocular hypertension. Expert Opinion on Drug Safety 21:4, pages 525-539.
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Anastasios G. Konstas, Antoine Labbé, Andreas Katsanos, Frances Meier-Gibbons, Murat Irkec, Konstadinos G. Boboridis, Gábor Holló, Julián García-Feijoo, Gordon N. Dutton & Christophe Baudouin. (2021) The treatment of glaucoma using topical preservative-free agents: an evaluation of safety and tolerability. Expert Opinion on Drug Safety 20:4, pages 453-466.
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Sarah MacIver, Nicole Stout & Olivia Ricci. (2021) New considerations for the clinical efficacy of old and new topical glaucoma medications. Clinical and Experimental Optometry 104:3, pages 350-366.
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Viran Jayanetti, Sartaj Sandhu & Jed A Lusthaus. (2020) The Latest Drugs in Development That Reduce Intraocular Pressure in Ocular Hypertension and Glaucoma. Journal of Experimental Pharmacology 12, pages 539-548.
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Anastasios G. Konstas, Leopold Schmetterer, Vital P. Costa, Gábor Holló, Andreas Katsanos, Philippe Denis, Luciano Quaranta, Murat Irkec, Miguel A. Castejón, Miguel A. Teus & Alan L. Robin. (2020) Current and emerging fixed combination therapies in glaucoma: a safety and tolerability review. Expert Opinion on Drug Safety 19:11, pages 1445-1460.
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Khulood Muhammad Sayed, Engy Mohammed Mostafa, Amr Mounir, Nesreen G Abd Elhaliem & Alahmady Hamad Alsmman. (2019) Analysis of Bimatoprost-Induced changes on Rabbits eyelash Follicle: Clinical and Electron microscopic study. Clinical Ophthalmology 13, pages 2421-2426.
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Andrea Angeli & Claudiu T Supuran. (2019) Prostaglandin receptor agonists as antiglaucoma agents (a patent review 2013 – 2018). Expert Opinion on Therapeutic Patents 29:10, pages 793-803.
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Sapir Karli, Juan Alfredo Ayala-Haedo, William J Feuer, Maria Fernandez, Sander Dubovy & Sara T Wester. (2018) Effect of prostaglandin analogs on matrix metalloproteinases and tissue inhibitor of metalloproteinases in eyelid muscle specimens. Clinical Ophthalmology 12, pages 2039-2046.
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Anastasios G. P. Konstas & Gabor Holló. (2016) Preservative-free tafluprost/timolol fixed combination: a new opportunity in the treatment of glaucoma. Expert Opinion on Pharmacotherapy 17:9, pages 1271-1283.
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Yuan Fang, Zhihong Ling & Xinghuai Sun. (2015) Fixed-combination treatments for intraocular hypertension in Chinese patients – focus on bimatoprost-timolol. Drug Design, Development and Therapy 9, pages 2617-2625.
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Katsuhiko Maruyama, Asako Tsuchisaka, Jumpei Sakamoto, Shiroaki Shirato & Hiroshi Goto. (2013) Incidence of deepening of upper eyelid sulcus after topical use of tafluprost ophthalmic solution in Japanese patients. Clinical Ophthalmology 7, pages 1441-1446.
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Nathan V Harms & Carol B Toris. (2013) Current status of unoprostone for the management of glaucoma and the future of its use in the treatment of retinal disease. Expert Opinion on Pharmacotherapy 14:1, pages 105-113.
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Donald R Nixon, Susan Simonyi, Meetu Bhogal, Christopher S Sigouin, Andrew C Crichton, Marino Discepola, Cindy ML Hutnik & David B Yan. (2012) An observational study of bimatoprost 0.01% in treatment-naïve patients with primary open angle glaucoma or ocular hypertension: the CLEAR trial. Clinical Ophthalmology 6, pages 2097-2103.
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Maurizio Digiuni, Paolo Fogagnolo & Luca Rossetti. (2012) A review of the use of latanoprost for glaucoma since its launch. Expert Opinion on Pharmacotherapy 13:5, pages 723-745.
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David Wirta, Amanda M VanDenburgh, Emily Weng, Scott M Whitcup, Sef Kurstjens & Frederick C Beddingfield$suffix/text()$suffix/text(). (2011) Long-term safety evaluation of bimatoprost ophthalmic solution 0.03%: a pooled analysis of six double-masked, randomized, active-controlled clinical trials. Clinical Ophthalmology 5, pages 759-765.
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Marina Papadia, Alessandro Bagnis, Riccardo Scotto & Carlo E Traverso. (2011) Tafluprost for glaucoma. Expert Opinion on Pharmacotherapy 12:15, pages 2393-2401.
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Steven Fagien. (2010) Management of hypotrichosis of the eyelashes: Focus on bimatoprost. Clinical, Cosmetic and Investigational Dermatology 3, pages 39-48.
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E Randy Craven, Ching-Chi Liu, Amy Batoosingh, Rhett M Schiffman & Scott M Whitcup. (2010) A randomized, controlled comparison of macroscopic conjunctival hyperemia in patients treated with bimatoprost 0.01% or vehicle who were previously controlled on latanoprost. Clinical Ophthalmology 4, pages 1433-1440.
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Dietmar Schnober, Günter Hofmann, Hubert Maier, Maria-Luise Scherzer, Abayomi B Ogundele & Mark C Jasek. (2010) Diurnal IOP-lowering efficacy and safety of travoprost 0.004% compared with tafluprost 0.0015% in patients with primary open-angle glaucoma or ocular hypertension. Clinical Ophthalmology 4, pages 1459-1463.
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Anuradha Jayaprakasam & Seyed Ghazi-Nouri. (2010) Periorbital Fat Atrophy — An Unfamiliar Side Effect of Prostaglandin Analogues. Orbit 29:6, pages 357-359.
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Sayime Aydin, Işıl Işıklıgil, Yasemin Aktan Tekşen & Erkin Kir. (2010) Recovery of orbital fat pad prolapsus and deepening of the lid sulcus from topical bimatoprost therapy: 2 case reports and review of the literature. Cutaneous and Ocular Toxicology 29:3, pages 212-216.
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Oghenowede Eyawo, Jean Nachega, Pierre Lefebvre, David Meyer, Beth Rachlis, Chia-Wen Lee, Steven Kelly & Edward Mills. (2009) Efficacy and safety of prostaglandin analogues in patients with predominantly primary open-angle glaucoma or ocular hypertension: a meta-analysis. Clinical Ophthalmology 3, pages 447-456.
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Ciro Costagliola, Roberto dell’Omo, Mario R Romano, Michele Rinaldi, Lucia Zeppa & Francesco Parmeggiani. (2009) Pharmacotherapy of intraocular pressure – part II. Carbonic anhydrase inhibitors, prostaglandin analogues and prostamides. Expert Opinion on Pharmacotherapy 10:17, pages 2859-2870.
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Philippe Denis, David Covert & Anthony Realini. (2007) Travoprost in the management of open-angle glaucoma and ocular hypertension. Clinical Ophthalmology 1:1, pages 11-24.
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M Figus, M Nardi, P Piaggi, M Sartini, G Guidi, L Martini & S Lazzeri. (2014) Bimatoprost 0.01% vs bimatoprost 0.03%: a 12-month prospective trial of clinical and in vivo confocal microscopy in glaucoma patients. Eye 28:4, pages 422-429.
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Douglas G Day, Thomas R Walters, Gail F Schwartz, Thomas K Mundorf, Charlie Liu, Rhett M Schiffman & Marina Bejanian. (2013) Bimatoprost 0.03% preservative-free ophthalmic solution versus bimatoprost 0.03% ophthalmic solution (Lumigan) for glaucoma or ocular hypertension: a 12-week, randomised, double-masked trial. British Journal of Ophthalmology 97:8, pages 989-993.
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Iwona Dams, Jaromir Wasyluk, Marek Prost & Andrzej Kutner. (2013) Therapeutic uses of prostaglandin F2α analogues in ocular disease and novel synthetic strategies. Prostaglandins & Other Lipid Mediators 104-105, pages 109-121.
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Andrew C. S. Crichton, Steven Vold, Julia M. Williams & David A. Hollander. (2013) Ocular Surface Tolerability of Prostaglandin Analogs and Prostamides in Patients with Glaucoma or Ocular Hypertension. Advances in Therapy 30:3, pages 260-270.
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Martina Tomić, Snježana Kaštelan, Kata Metež Soldo & Jasminka Salopek-Rabatić. (2013) Influence of BAK-Preserved Prostaglandin Analog Treatment on the Ocular Surface Health in Patients with Newly Diagnosed Primary Open-Angle Glaucoma. BioMed Research International 2013, pages 1-7.
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Suping Cai, Xiaomin Zhou, Naihong Yan, Xuyang Liu & Xiaohong Li. (2013) Possible mechanism for the gastro-intestinal adverse effects upon topical application of Prostaglandin F2α analogs. Medical Hypotheses 80:1, pages 32-35.
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