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Expert Opinion on Drug Safety Volume 7, 2008 - Issue 2
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Review

Antiepileptic drugs as human teratogens

Mervyn J Eadie Emeritus Professor of Clinical Neurology and Neuropharmacology, University of Queensland, Honorary Consultant Neurologist Royal Brisbane and Women's Hospital, Herston, Brisbane, Australia 4029, Australia +61 7 38311704; +61 7 38325608; [email protected]
, AO MD PhD FRCP Ed FRACP
Pages 195-209 | Published online: 06 Mar 2008

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FJE Vajda. (2008) Treatment options for pregnant women with epilepsy. Expert Opinion on Pharmacotherapy 9:11, pages 1859-1868.
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Articles from other publishers (28)

Daisuke Ibi, Yu Fujiki, Nayu Koide, Genki Nakasai, Rika Takaba & Masayuki Hiramatsu. (2019) Paternal valproic acid exposure in mice triggers behavioral alterations in offspring. Neurotoxicology and Teratology 76, pages 106837.
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M. Karbhari Pawar & V. Zawar. (2019) Congenital Absence of Nails and Digital-Type Thumb due to Prenatal Phenytoin Exposure. Actas Dermo-Sifiliográficas (English Edition) 110:9, pages 778-779.
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M. Karbhari Pawar & V. Zawar. (2019) Ausencia congénita de uñas y pulgar digitalizado debida a la exposición prenatal a fenitoína. Actas Dermo-Sifiliográficas 110:9, pages 778-780.
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MJ Eadie. (2018) The management of epilepsy during pregnancy. Future Neurology 13:3, pages 123-125.
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Hyun Myung KoYeonsun JinHyun Ho ParkJong Hyuk LeeSeung Hyo JungSo Young ChoiSung Hoon LeeChan Young Shin. (2018) Dual mechanisms for the regulation of brain-derived neurotrophic factor by valproic acid in neural progenitor cells. The Korean Journal of Physiology & Pharmacology 22:6, pages 679.
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Ramesh Devkota, G. M. Khan, Kadir Alam, Amisha Regmi & Binaya Sapkota. (2016) Medication utilization pattern for management of pregnancy complications: a study in Western Nepal. BMC Pregnancy and Childbirth 16:1.
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MJ Eadie & FJE VajdaMJ Eadie & FJE Vajda. 2016. Antiepileptic Drugs and Pregnancy. Antiepileptic Drugs and Pregnancy 153 174 .
Enrico Valerio, Francesca Favot, Ilaria Mattei & Mario Cutrone. (2015) Congenital isolated Iso–Kikuchi syndrome in a newborn. Clinical Case Reports 3:10, pages 866-869.
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Dania Cheaha, Sara Bumrungsri, Surapong Chatpun & Ekkasit Kumarnsit. (2015) Characterization of in utero valproic acid mouse model of autism by local field potential in the hippocampus and the olfactory bulb. Neuroscience Research 98, pages 28-34.
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Frank J.E. Vajda. 2015. Epilepsy and the interictal state. Epilepsy and the interictal state 136 144 .
Peter G. J. Nikkels. 2015. Keeling’s Fetal and Neonatal Pathology. Keeling’s Fetal and Neonatal Pathology 413 448 .
Sarah J. White, Howard P. Hendrickson, William T. Atchley, Elizabeth M. Laurenzana, W. Brooks Gentry, D. Keith Williams & S. Michael Owens. (2014) Treatment with a Monoclonal Antibody against Methamphetamine and Amphetamine Reduces Maternal and Fetal Rat Brain Concentrations in Late Pregnancy. Drug Metabolism and Disposition 42:8, pages 1285-1291.
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Frank J.E. Vajda. (2014) Effect of anti-epileptic drug therapy on the unborn child. Journal of Clinical Neuroscience 21:5, pages 716-721.
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Frank Vajda. (2013) Effects of exposure to antiepileptic drugs during development. Nature Reviews Neurology 10:1, pages 11-12.
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Linda de Jonge, Priscilla A. Zetstra-van der Woude, H. Jens Bos, Lolkje T. W. de Jong-van den Berg & Marian K. Bakker. (2013) Identifying Associations between Maternal Medication Use and Birth Defects Using a Case-Population Approach: An Exploratory Study on Signal Detection. Drug Safety 36:11, pages 1069-1078.
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R Fujiki, A Sato, M Fujitani & T Yamashita. (2013) A proapoptotic effect of valproic acid on progenitors of embryonic stem cell-derived glutamatergic neurons. Cell Death & Disease 4:6, pages e677-e677.
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K. A. Lloyd. (2013) A scientific review: mechanisms of valproate-mediated teratogenesis. Bioscience Horizons 6:0, pages hzt003-hzt003.
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Shunsuke Kataoka, Kazuhiro Takuma, Yuta Hara, Yuko Maeda, Yukio Ago & Toshio Matsuda. (2013) Autism-like behaviours with transient histone hyperacetylation in mice treated prenatally with valproic acid. International Journal of Neuropsychopharmacology 16:1, pages 91-103.
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Sung Hak Lee, Jung Won Kang, Tao Lin, Jae Eun Lee & Dong Il Jin. (2013) Teratogenic Potential of Antiepileptic Drugs in the Zebrafish Model. BioMed Research International 2013, pages 1-6.
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Michael Levine & Ayrn D. O'Connor. (2012) Obstetric Toxicology. Emergency Medicine Clinics of North America 30:4, pages 977-990.
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E. Robert-Gnansia, H. Cissoko, E. Polard, J. Lacotte, F. Colin & A.-P. Jonville-Béra. 2012. Médicaments et Grossesse : Prescrire et évaluer le Risque. Médicaments et Grossesse : Prescrire et évaluer le Risque 169 186 .
Frank J E VajdaTerence J O'BrienCecilie M LanderMervyn J Eadie. (2011) The rationale for pregnancy registers for women with epilepsy. Medical Journal of Australia 195:1, pages 8-9.
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Ilan Matok, Anna Pupco & Gideon Koren. (2011) Drug Exposure in Pregnancy and Heart Defects. Journal of Cardiovascular Pharmacology 58:1, pages 20-24.
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Teri Pearlstein & Jami Star. 2010. de Swiet's Medical Disorders in Obstetric Practice. de Swiet's Medical Disorders in Obstetric Practice 524 552 .
D.K. Hansen. 2010. Comprehensive Toxicology. Comprehensive Toxicology 177 187 .
Bryan M. Turner. (2009) Epigenetic responses to environmental change and their evolutionary implications. Philosophical Transactions of the Royal Society B: Biological Sciences 364:1534, pages 3403-3418.
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Ha T. T. Nguyen, Verinder Sharma & Roger S. McIntyre. (2009) Teratogenesis associated with antibipolar agents. Advances in Therapy 26:3, pages 281-294.
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Dileep K Rohra, Nirmal Das, Syed I Azam, Nazir A Solangi, Zahida Memon, Abdul M Shaikh & Nusrat H Khan. (2008) Drug-prescribing patterns during pregnancy in the tertiary care hospitals of Pakistan: a cross sectional study. BMC Pregnancy and Childbirth 8:1.
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