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Current approaches to stabilising and analysing proteins during microencapsulation in PLGA

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Pages 177-186 | Published online: 24 Feb 2009

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Jing Li, Rong Zhang, Huiqing Yang & Yanming Wei. (2022) Enhanced stability of foot-and-mouth disease vaccine antigens with a novel formulation. Pharmaceutical Development and Technology 27:7, pages 759-765.
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Lene Jorgensen, Susanne Hostrup, Eva Horn Moeller & Holger Grohganz. (2009) Recent trends in stabilising peptides and proteins in pharmaceutical formulation – considerations in the choice of excipients. Expert Opinion on Drug Delivery 6:11, pages 1219-1230.
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Sara Mohajeri & Brian G Amsden. (2021) In Vivo Degradation Mechanism and Biocompatibility of a Biodegradable Aliphatic Polycarbonate: Poly(Trimethylene Carbonate- co -5-Hydroxy Trimethylene Carbonate) . ACS Applied Bio Materials 4:4, pages 3686-3696.
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Karina C. Scheiner, Roel F. Maas-Bakker, Mies J. van Steenbergen, Steven P. Schwendeman, Wim E. Hennink & Robbert J. Kok. (2021) Post-loading of proangiogenic growth factors in PLGA microspheres. European Journal of Pharmaceutics and Biopharmaceutics 158, pages 1-10.
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Dimitra A. Louka, Nathan Holwell, Brandon H. Thomas, Fei Chen & Brian G. Amsden. (2017) Highly Bioactive SDF-1α Delivery from Low-Melting-Point, Biodegradable Polymer Microspheres. ACS Biomaterials Science & Engineering 4:11, pages 3747-3758.
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Brian Amsden. (2015) Novel biodegradable polymers for local growth factor delivery. European Journal of Pharmaceutics and Biopharmaceutics 97, pages 318-328.
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Ronak B. Shah & Steven P. Schwendeman. (2014) A biomimetic approach to active self-microencapsulation of proteins in PLGA. Journal of Controlled Release 196, pages 60-70.
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Tuna Yucel, Michael L. Lovett, Raffaella Giangregorio, Erin Coonahan & David L. Kaplan. (2014) Silk fibroin rods for sustained delivery of breast cancer therapeutics. Biomaterials 35:30, pages 8613-8620.
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Dario Puppi, Xuanmiao Zhang, Likai Yang, Federica Chiellini, Xun Sun & Emo Chiellini. (2014) Nano/microfibrous polymeric constructs loaded with bioactive agents and designed for tissue engineering applications: A review. Journal of Biomedical Materials Research Part B: Applied Biomaterials 102:7, pages 1562-1579.
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Tuna Yucel, Michael L. Lovett & David L. Kaplan. (2014) Silk-based biomaterials for sustained drug delivery. Journal of Controlled Release 190, pages 381-397.
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Steven P. Schwendeman, Ronak B. Shah, Brittany A. Bailey & Anna S. Schwendeman. (2014) Injectable controlled release depots for large molecules. Journal of Controlled Release 190, pages 240-253.
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Xiaoming Chen, Yuying Liu, Lianyan Wang, Yuan Liu, Weifeng Zhang, Bei Fan, Xiaowei Ma, Qipeng Yuan, Guanghui Ma & Zhiguo Su. (2014) Enhanced Humoral and Cell-Mediated Immune Responses Generated by Cationic Polymer-Coated PLA Microspheres with Adsorbed HBsAg. Molecular Pharmaceutics 11:6, pages 1772-1784.
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Chandra Nugraha, Meghali Bora & Subbu S. Venkatraman. (2014) Release Retardation of Model Protein on Polyelectrolyte-Coated PLGA Nano- and Microparticles. PLoS ONE 9:3, pages e92393.
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Catarina Oliveira Silva, Bruno Sarmento & Catarina Pinto Reis. 2014. Mucosal Delivery of Biopharmaceuticals. Mucosal Delivery of Biopharmaceuticals 125 147 .
Samuel E. Reinhold & Steven P. Schwendeman. (2013) Effect of Polymer Porosity on Aqueous Self-Healing Encapsulation of Proteins in PLGA Microspheres. Macromolecular Bioscience 13:12, pages 1700-1710.
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Hongzhuo Liu, Yanyan Zhou, Shichao Chen, Meng Bu, Jiayu Xin & Sanming Li. (2013) Current sustained delivery strategies for the design of local neurotrophic factors in treatment of neurological disorders. Asian Journal of Pharmaceutical Sciences 8:5, pages 269-277.
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G. Sharma, C.F. van der Walle & M.N.V. Ravi Kumar. (2013) Antacid co-encapsulated polyester nanoparticles for peroral delivery of insulin: Development, pharmacokinetics, biodistribution and pharmacodynamics. International Journal of Pharmaceutics 440:1, pages 99-110.
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Francesca Ungaro, Ivana d' Angelo, Agnese Miro, Maria I La Rotonda & Fabiana Quaglia. (2012) Engineered PLGA nano- and micro-carriers for pulmonary delivery: challenges and promises. Journal of Pharmacy and Pharmacology 64:9, pages 1217-1235.
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Jason C. Stanwick, M. Douglas Baumann & Molly S. Shoichet. (2012) In vitro sustained release of bioactive anti-NogoA, a molecule in clinical development for treatment of spinal cord injury. International Journal of Pharmaceutics 426:1-2, pages 284-290.
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Sandy Vrignaud, Jean-Pierre Benoit & Patrick Saulnier. (2011) Strategies for the nanoencapsulation of hydrophilic molecules in polymer-based nanoparticles. Biomaterials 32:33, pages 8593-8604.
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Wei Ji, Yan Sun, Fang Yang, Jeroen J. J. P. van den Beucken, Mingwen Fan, Zhi Chen & John A. Jansen. (2010) Bioactive Electrospun Scaffolds Delivering Growth Factors and Genes for Tissue Engineering Applications. Pharmaceutical Research 28:6, pages 1259-1272.
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Ripal Gaudana, Varun Khurana, Ashwin Parenky & Ashim K. Mitra. (2011) Encapsulation of Protein-Polysaccharide HIP Complex in Polymeric Nanoparticles. Journal of Drug Delivery 2011, pages 1-7.
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Kristin Andreas, Rolf Zehbe, Maja Kazubek, Karolina Grzeschik, Nadine Sternberg, Hans Bäumler, Helmut Schubert, Michael Sittinger & Jochen Ringe. (2011) Biodegradable insulin-loaded PLGA microspheres fabricated by three different emulsification techniques: Investigation for cartilage tissue engineering. Acta Biomaterialia 7:4, pages 1485-1495.
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