Advanced search
Publication Cover
Expert Opinion on Drug Delivery Volume 6, 2009 - Issue 6
Submit an article Journal homepage
442
Views
24
CrossRef citations to date
0
Altmetric
Reviews

Targeted gene delivery to the lung

Manish K Aneja Ludwig-Maximilians University, Division of Molecular Pulmonology, Department of Paediatrics, Lindwurmstrasse 2A, D-80337 Munich, Germany
, PhD,
Johannes-Peter Geiger Ludwig-Maximilians University, Division of Molecular Pulmonology, Department of Paediatrics, Lindwurmstrasse 2A, D-80337 Munich, Germany; Free University of Berlin, Department of Pharmacy, Takustrasse 3, 14166 Berlin, Germany +49 8951607711; +49 8951604421; [email protected]
,
Anne Himmel Ludwig-Maximilians University, Division of Molecular Pulmonology, Department of Paediatrics, Lindwurmstrasse 2A, D-80337 Munich, Germany; Free University of Berlin, Department of Pharmacy, Takustrasse 3, 14166 Berlin, Germany +49 8951607711; +49 8951604421; [email protected]
&
Carsten Rudolph Ludwig-Maximilians University, Division of Molecular Pulmonology, Department of Paediatrics, Lindwurmstrasse 2A, D-80337 Munich, Germany; Free University of Berlin, Department of Pharmacy, Takustrasse 3, 14166 Berlin, Germany +49 8951607711; +49 8951604421; [email protected]
, PhD
Pages 567-583 | Published online: 19 May 2009

Citations (24)

Keep up to date with the latest research on this topic with citation updates for this article.

Subscribe to citation updates

Read on this site (2)

Ah Young Lee, Myung-Haing Cho & Sanghwa Kim. (2019) Recent advances in aerosol gene delivery systems using non-viral vectors for lung cancer therapy. Expert Opinion on Drug Delivery 16:7, pages 757-772.
Read now
Helene Kettiger, Angela Schipanski, Peter Wick & Jörg Huwyler. (2013) Engineered nanomaterial uptake and tissue distribution: from cell to organism. International Journal of Nanomedicine 8, pages 3255-3269.
Read now

Articles from other publishers (22)

Arvind KonkimallaZachary ElmoreSatoshi KonishiLauren MacadloHiroaki KatsuraAleksandra TataAravind Asokan & Purushothama Rao Tata. (2023) Efficient Adeno-associated Virus–mediated Transgenesis in Alveolar Stem Cells and Associated Niches. American Journal of Respiratory Cell and Molecular Biology 69:3, pages 255-265.
Crossref
Lingling Dai & Lizhong Du. (2022) Genes in pediatric pulmonary arterial hypertension and the most promising BMPR2 gene therapy. Frontiers in Genetics 13.
Crossref
Malik Bisserier, Xiao-Qing Sun, Shahood Fazal, Irene C. Turnbull, Sébastien Bonnet & Lahouaria Hadri. (2022) Novel Insights into the Therapeutic Potential of Lung-Targeted Gene Transfer in the Most Common Respiratory Diseases. Cells 11:6, pages 984.
Crossref
Jing Liu & David A. Dean. (2022) Gene Therapy for Acute Respiratory Distress Syndrome. Frontiers in Physiology 12.
Crossref
Yuta Hagino, Ikramy A. Khalil, Seigo Kimura, Kenji Kusumoto & Hideyoshi Harashima. (2021) GALA-Modified Lipid Nanoparticles for the Targeted Delivery of Plasmid DNA to the Lungs. Molecular Pharmaceutics 18:3, pages 878-888.
Crossref
Martin H. Kang, Laura P. van Lieshout, Liqun Xu, Jakob M. Domm, Arul Vadivel, Laurent Renesme, Christian Mühlfeld, Maria Hurskainen, Ivana Mižíková, Yanlong Pei, Jacob P. van Vloten, Sylvia P. Thomas, Claudia Milazzo, Chanèle Cyr-Depauw, Jeffrey A. Whitsett, Lawrence M. Nogee, Sarah K. Wootton & Bernard Thébaud. (2020) A lung tropic AAV vector improves survival in a mouse model of surfactant B deficiency. Nature Communications 11:1.
Crossref
Stephen P. Newman. (2018) Delivering drugs to the lungs: The history of repurposing in the treatment of respiratory diseases. Advanced Drug Delivery Reviews 133, pages 5-18.
Crossref
Dolan SondhiKatie M. StilesBishnu P. DeRonald G. Crystal. (2017) Genetic Modification of the Lung Directed Toward Treatment of Human Disease. Human Gene Therapy 28:1, pages 3-84.
Crossref
Vivek Badwaik, Linjia Liu, Dinara Gunasekera, Aditya Kulkarni & David H. Thompson. (2016) Mechanistic Insight into Receptor-Mediated Delivery of Cationic-β-Cyclodextrin:Hyaluronic Acid-Adamantamethamidyl Host:Guest pDNA Nanoparticles to CD44 + Cells . Molecular Pharmaceutics 13:3, pages 1176-1184.
Crossref
Jens Lipka, Manuela Semmler-Behnke, Alexander Wenk, Jana Burkhardt, Achim Aigner & Wolfgang Kreyling. (2016) Biokinetic studies of non-complexed siRNA versus nano-sized PEI F25-LMW/siRNA polyplexes following intratracheal instillation into mice. International Journal of Pharmaceutics 500:1-2, pages 227-235.
Crossref
Jung Soo Suk. (2016) Could recent advances in DNA-loaded nanoparticles lead to effective inhaled gene therapies?. Nanomedicine 11:3, pages 193-196.
Crossref
Sante Di Gioia, Adriana Trapani, Stefano Castellani, Annalucia Carbone, Giuliana Belgiovine, Emanuela Fabiola Craparo, Giovanni Puglisi, Gennara Cavallaro, Giuseppe Trapani & Massimo Conese. (2015) Nanocomplexes for gene therapy of respiratory diseases: Targeting and overcoming the mucus barrier. Pulmonary Pharmacology & Therapeutics 34, pages 8-24.
Crossref
Sung K. Moon & David J. Lim. (2015) Intratympanic Gene Delivery of Antimicrobial Molecules in Otitis Media. Current Allergy and Asthma Reports 15:4.
Crossref
A. HibbittsA.M. O'MahonyE. FordeL. NolanJ. OgierS. DesgrangesR. DarcyR. MacLoughlinC.M. O'DriscollS.A. Cryan. (2014) Early-Stage Development of Novel Cyclodextrin-siRNA Nanocomplexes Allows for Successful Postnebulization Transfection of Bronchial Epithelial Cells. Journal of Aerosol Medicine and Pulmonary Drug Delivery 27:6, pages 466-477.
Crossref
Christian A Ruge, Julian Kirch & Claus-Michael Lehr. (2013) Pulmonary drug delivery: from generating aerosols to overcoming biological barriers—therapeutic possibilities and technological challenges. The Lancet Respiratory Medicine 1:5, pages 402-413.
Crossref
Moritz Beck-Broichsitter, Olivia M. Merkel & Thomas Kissel. (2012) Controlled pulmonary drug and gene delivery using polymeric nano-carriers. Journal of Controlled Release 161:2, pages 214-224.
Crossref
Guenther Hasenpusch, Johannes Geiger, Kai Wagner, Olga Mykhaylyk, Frank Wiekhorst, Lutz Trahms, Alexandra Heidsieck, Bernhard Gleich, Christian Bergemann, Manish K. Aneja & Carsten Rudolph. (2012) Magnetized Aerosols Comprising Superparamagnetic Iron Oxide Nanoparticles Improve Targeted Drug and Gene Delivery to the Lung. Pharmaceutical Research 29:5, pages 1308-1318.
Crossref
Olivia M. Merkel, Mengyao Zheng, Heiko Debus & Thomas Kissel. (2011) Pulmonary Gene Delivery Using Polymeric Nonviral Vectors. Bioconjugate Chemistry 23:1, pages 3-20.
Crossref
S. Al-Qadi, A. Grenha & C. Remuñán-López. (2012) Chitosan and its derivatives as nanocarriers for siRNA delivery. Journal of Drug Delivery Science and Technology 22:1, pages 29-42.
Crossref
G?nther Hasenpusch, Corinna Pfeifer, Manish Kumar Aneja, Kai Wagner, Dietrich Reinhardt, Michal Gilon, Patricia Ohana, Avraham Hochberg & Carsten Rudolph. (2011) Aerosolized BC-819 Inhibits Primary but Not Secondary Lung Cancer Growth. PLoS ONE 6:6, pages e20760.
Crossref
John Cannon. 2011. Drug Delivery Systems, Third Edition. Drug Delivery Systems, Third Edition 305 371 .
Simon Heuking & Gerrit Borchard. 2011. Controlled Pulmonary Drug Delivery. Controlled Pulmonary Drug Delivery 367 381 .

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.