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Advances with the use of bio-inspired vectors towards creation of artificial viruses

, , & , PhD
Pages 497-512 | Published online: 13 Feb 2010

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Grace Cole, Joanne McCaffrey, Ahlam A. Ali, John W. McBride, Cian M. McCrudden, Eva M. Vincente-Perez, Ryan F. Donnelly & Helen O. McCarthy. (2017) Dissolving microneedles for DNA vaccination: Improving functionality via polymer characterization and RALA complexation. Human Vaccines & Immunotherapeutics 13:1, pages 50-62.
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Articles from other publishers (24)

Ashraf S.A. El-Sayed, Nabil Z. Mohamed, Marwa A. Yassin, Mahmoud M. Amer, Reyad El-Sharkawy, Nesma El-Sayed & Mostafa G. Ali. (2022) Microbial cytosine deaminase is a programmable anticancer prodrug mediating enzyme: antibody, and gene directed enzyme prodrug therapy. Heliyon 8:9, pages e10660.
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Zinovia Tsitrouli, Maria-Anna Akritidou, Savvas Genitsaris & Gijsbert van Willigen. (2021) Treatment of Rheumatoid Arthritis with Gene Therapy Applications: Biosafety and Bioethical Considerations. BioTech 10:3, pages 11.
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Eva C. Thuenemann, Duc H. T. Le, George P. Lomonossoff & Nicole F. Steinmetz. (2021) Bluetongue Virus Particles as Nanoreactors for Enzyme Delivery and Cancer Therapy. Molecular Pharmaceutics 18:3, pages 1150-1156.
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Yi Yu, Yang Zhao, Guangming Zhou & Xiang Wang. (2020) Therapeutic Efficacy of Delta-Like Ligand 4 Gene Vaccine Overexpression on Liver Cancer in Mice. Technology in Cancer Research & Treatment 19, pages 153303382094220.
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Grace Cole, Ahlam A. Ali, Emma McErlean, Eoghan J. Mulholland, Amy Short, Cian M. McCrudden, Joanne McCaffrey, Tracy Robson, Vicky L. Kett, Jonathan A. Coulter, Nicholas J. Dunne, Ryan F. Donnelly & Helen O. McCarthy. (2019) DNA vaccination via RALA nanoparticles in a microneedle delivery system induces a potent immune response against the endogenous prostate cancer stem cell antigen. Acta Biomaterialia 96, pages 480-490.
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Grace Cole, Nicholas J. Dunne & Helen O. McCarthy. 2018. Microneedles for Drug and Vaccine Delivery and Patient Monitoring. Microneedles for Drug and Vaccine Delivery and Patient Monitoring 129 175 .
Xuguang Chen, Alireza Nomani, Niket Patel, Faranak S. Nouri & Arash Hatefi. (2018) Bioengineering a non-genotoxic vector for genetic modification of mesenchymal stem cells. Biomaterials 152, pages 1-14.
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Arash Hatefi, Zahra Karjoo & Alireza Nomani. (2017) Development of a Recombinant Multifunctional Biomacromolecule for Targeted Gene Transfer to Prostate Cancer Cells. Biomacromolecules 18:9, pages 2799-2807.
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Rachael Mooney, Asma Abdul Majid, Jennifer Batalla, Alexander J. Annala & Karen S. Aboody. (2017) Cell-mediated enzyme prodrug cancer therapies. Advanced Drug Delivery Reviews 118, pages 35-51.
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Xuguang Chen, Alireza Nomani, Niket Patel & Arash Hatefi. (2017) Production of low-expressing recombinant cationic biopolymers with high purity. Protein Expression and Purification 134, pages 11-17.
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Asia Majidi, Maryam Nikkhah, Faranak Sadeghian & Saman Hosseinkhani. (2016) Development of novel recombinant biomimetic chimeric MPG-based peptide as nanocarriers for gene delivery: Imitation of a real cargo. European Journal of Pharmaceutics and Biopharmaceutics 107, pages 191-204.
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Emma M McErlean, Cian M McCrudden & Helen O McCarthy. (2016) Delivery of nucleic acids for cancer gene therapy: overcoming extra- and intra-cellular barriers. Therapeutic Delivery 7:9, pages 619-637.
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Zahra Karjoo, Xuguang Chen & Arash Hatefi. (2016) Progress and problems with the use of suicide genes for targeted cancer therapy. Advanced Drug Delivery Reviews 99, pages 113-128.
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Joanne McCaffrey, Cian M. McCrudden, Ahlam A. Ali, Ashley S. Massey, John W. McBride, Maelíosa T.C. McCrudden, Eva M. Vicente-Perez, Jonathan A. Coulter, Tracy Robson, Ryan F. Donnelly & Helen O. McCarthy. (2016) Transcending epithelial and intracellular biological barriers; a prototype DNA delivery device. Journal of Controlled Release 226, pages 238-247.
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Grace Cole, Joanne McCaffrey, Ahlam A. Ali & Helen O. McCarthy. (2015) DNA vaccination for prostate cancer: key concepts and considerations. Cancer Nanotechnology 6:1.
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Rachel Bennett, Anita Yakkundi, Hayley D McKeen, Lana McClements, Thomas J McKeogh, Cian M McCrudden, Kenneth Arthur, Tracy Robson & Helen O McCarthy. (2015) RALA-mediated delivery of FKBPL nucleic acid therapeutics. Nanomedicine 10:19, pages 2989-3001.
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Joanne McCaffrey, Ryan F. Donnelly & Helen O. McCarthy. (2015) Microneedles: an innovative platform for gene delivery. Drug Delivery and Translational Research 5:4, pages 424-437.
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Tony Le Gall, Julie Barbeau, Sylvain Barrier, Mathieu Berchel, Loïc Lemiègre, Jelena Jeftić, Cristelle Meriadec, Franck Artzner, Deborah R. Gill, Stephen C. Hyde, Claude Férec, Pierre Lehn, Paul-Alain Jaffrès, Thierry Benvegnu & Tristan Montier. (2014) Effects of a Novel Archaeal Tetraether-Based Colipid on the In Vivo Gene Transfer Activity of Two Cationic Amphiphiles . Molecular Pharmaceutics 11:9, pages 2973-2988.
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Helen O. McCarthy, Joanne McCaffrey, Cian M. McCrudden, Aleksey Zholobenko, Ahlam A. Ali, John W. McBride, Ashley S. Massey, Sreekanth Pentlavalli, Kun-Hung Chen, Grace Cole, Stephen P. Loughran, Nicholas J. Dunne, Ryan F. Donnelly, Victoria L. Kett & Tracy Robson. (2014) Development and characterization of self-assembling nanoparticles using a bio-inspired amphipathic peptide for gene delivery. Journal of Controlled Release 189, pages 141-149.
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Tony Le Gall, Mathieu Berchel, Sophie Le Hir, Aurore Fraix, Jean Yves Salaün, Claude Férec, Pierre Lehn, Paul-Alain Jaffrès & Tristan Montier. (2013) Arsonium-Containing Lipophosphoramides, Poly-Functional Nano-Carriers for Simultaneous Antibacterial Action and Eukaryotic Cell Transfection. Advanced Healthcare Materials 2:11, pages 1513-1524.
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She-fang Ye, Miao-miao Tian, Tian-xiao Wang, Lei Ren, Dong Wang, Li-hua Shen & Ting Shang. (2012) Synergistic effects of cell-penetrating peptide Tat and fusogenic peptide HA2-enhanced cellular internalization and gene transduction of organosilica nanoparticles. Nanomedicine: Nanotechnology, Biology and Medicine 8:6, pages 833-841.
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Mathieu Berchel, Tony Le Gall, Hélène Couthon-Gourvès, Jean-Pierre Haelters, Tristan Montier, Patrick Midoux, Pierre Lehn & Paul-Alain Jaffrès. (2012) Lipophosphonate/lipophosphoramidates: A family of synthetic vectors efficient for gene delivery. Biochimie 94:1, pages 33-41.
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Yuhua Wang, Brenda F. Canine & Arash Hatefi. (2011) HSV-TK/GCV cancer suicide gene therapy by a designed recombinant multifunctional vector. Nanomedicine: Nanotechnology, Biology and Medicine 7:2, pages 193-200.
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Brenda F. Canine, Yuhua Wang, Wenyun Ouyang & Arash Hatefi. (2011) Development of targeted recombinant polymers that can deliver siRNA to the cytoplasm and plasmid DNA to the cell nucleus. Journal of Controlled Release 151:1, pages 95-101.
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