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Review

Drug delivery strategies for cathepsin inhibitors in joint diseases

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Pages 1015-1028 | Published online: 04 Nov 2005

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Nishkantha Arulkumaran, Robert J Unwin & Frederick WK Tam. (2011) A potential therapeutic role for P2X7 receptor (P2X7R) antagonists in the treatment of inflammatory diseases. Expert Opinion on Investigational Drugs 20:7, pages 897-915.
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Dieter Brömme & Fabien Lecaille. (2009) Cathepsin K inhibitors for osteoporosis and potential off-target effects. Expert Opinion on Investigational Drugs 18:5, pages 585-600.
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Ingo H Tarner & Ulf Müller-Ladner. (2008) Drug delivery systems for the treatment of rheumatoid arthritis. Expert Opinion on Drug Delivery 5:9, pages 1027-1037.
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Articles from other publishers (15)

Surinder M. Soond, Maria V. Kozhevnikova, Anastasia S. Frolova, Lyudmila V. Savvateeva, Egor Y. Plotnikov, Paul A. Townsend, Yuan-Ping Han & Andrey A. ZamyatninJr.Jr.. (2019) Lost or Forgotten: The nuclear cathepsin protein isoforms in cancer. Cancer Letters 462, pages 43-50.
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Fan Cao, Li-Qin Hu, Shu-Ran Yao, Yan Hu, De-Guang Wang, Yin-Guang Fan, Gui-Xia Pan, Sha-Sha Tao, Qin Zhang, Hai-Feng Pan & Guo-Cui Wu. (2019) P2X7 receptor: A potential therapeutic target for autoimmune diseases. Autoimmunity Reviews 18:8, pages 767-777.
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Vijay A. Pawar, Arehalli S. Manjappa, Prashant R. Murumkar, Tejal K. Gajaria, Ranjisinh V. Devkar, Anil K. Mishra & Mange Ram Yadav. (2018) Drug-fortified liposomes as carriers for sustained release of NSAIDs: The concept and its validation in the animal model for the treatment of arthritis. European Journal of Pharmaceutical Sciences 125, pages 11-22.
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M. A. Fomina & A. A. Terent'ev. (2018) Сhanges in subcellular distribution of lysosomal cysteine proteinases activity in parenchymatous organs of rats under the action of nitric oxide synthesis modulators. Research'n Practical Medicine Journal 5:3, pages 28-39.
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Shengfu Piao & Ravi K. Amaravadi. (2016) Targeting the lysosome in cancer. Annals of the New York Academy of Sciences 1371:1, pages 45-54.
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B. Sterner, M. Harms, M. Weigandt, M. Windbergs & C.M. Lehr. (2014) Crystal suspensions of poorly soluble peptides for intra-articular application: A novel approach for biorelevant assessment of their in vitro release. International Journal of Pharmaceutics 461:1-2, pages 46-53.
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Stefanie Grimm, Melanie Horlacher, Betül Catalgol, Annika Hoehn, Thomas Reinheckel & Tilman Grune. (2012) Cathepsins D and L reduce the toxicity of advanced glycation end products. Free Radical Biology and Medicine 52:6, pages 1011-1023.
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Alberto Baroja-Mazo & Pablo Pelegrín. (2012) Modulating P2X7 Receptor Signaling during Rheumatoid Arthritis: New Therapeutic Approaches for Bisphosphonates. Journal of Osteoporosis 2012, pages 1-7.
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Vito Turk, Veronika Stoka, Olga Vasiljeva, Miha Renko, Tao Sun, Boris Turk & Dušan Turk. (2012) Cysteine cathepsins: From structure, function and regulation to new frontiers. Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics 1824:1, pages 68-88.
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Gloria Lopez-Castejon, Jill Theaker, Pablo Pelegrin, Andrew D. Clifton, Martin Braddock & Annmarie Surprenant. (2010) P2X7 Receptor-Mediated Release of Cathepsins from Macrophages Is a Cytokine-Independent Mechanism Potentially Involved in Joint Diseases. The Journal of Immunology 185:4, pages 2611-2619.
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Julia Dennemärker, Tobias Lohmüller, Sebastian Müller, Stephanie Vargas Aguilar, Desmond J. Tobin, Christoph Peters & Thomas Reinheckel. (2010) Impaired turnover of autophagolysosomes in cathepsin L deficiency. Biological Chemistry 391:8.
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Sarah Cartmell. (2009) Controlled Release Scaffolds for Bone Tissue Engineering. Journal of Pharmaceutical Sciences 98:2, pages 430-441.
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H. Soto, P. Hevezi, R. B. Roth, A. Pahuja, D. Alleva, H. M. Acosta, C. Martinez, A. Ortega, A. Lopez, R. Araiza-Casillas & A. Zlotnik. (2008) Gene Array Analysis Comparison between Rat Collagen-induced Arthritis and Human Rheumatoid Arthritis. Scandinavian Journal of Immunology 68:1, pages 43-57.
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William C. Horne, Le T. Duong, Archana Sanjay & Roland Baron. 2008. Principles of Bone Biology. Principles of Bone Biology 221 236 .
Arnab K. Chatterjee, Hong Liu, David C. Tully, Jianhua Guo, Robert Epple, Ross Russo, Jennifer Williams, Michael Roberts, Tove Tuntland, Jonathan Chang, Perry Gordon, Thomas Hollenbeck, Christine Tumanut, Jun Li & Jennifer L. Harris. (2007) Synthesis and SAR of succinamide peptidomimetic inhibitors of cathepsin S. Bioorganic & Medicinal Chemistry Letters 17:10, pages 2899-2903.
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