779
Views
36
CrossRef citations to date
0
Altmetric
Reviews

In vitro and in vivo testing methods for respiratory drug delivery

&
Pages 57-69 | Published online: 22 Dec 2010

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (3)

Ah Young Lee, Myung-Haing Cho & Sanghwa Kim. (2019) Recent advances in aerosol gene delivery systems using non-viral vectors for lung cancer therapy. Expert Opinion on Drug Delivery 16:7, pages 757-772.
Read now
A. Kourmatzis, S. Cheng & H.-K. Chan. (2018) Airway geometry, airway flow, and particle measurement methods: implications on pulmonary drug delivery. Expert Opinion on Drug Delivery 15:3, pages 271-282.
Read now
Hui Xin Ong, Daniela Traini & Paul M Young. (2013) Pharmaceutical applications of the Calu-3 lung epithelia cell line. Expert Opinion on Drug Delivery 10:9, pages 1287-1302.
Read now

Articles from other publishers (33)

Sabrina Magramane, Kristina Vlahović, Péter Gordon, Nikolett Kállai-Szabó, Romána Zelkó, István Antal & Dóra Farkas. (2023) Inhalation Dosage Forms: A Focus on Dry Powder Inhalers and Their Advancements. Pharmaceuticals 16:12, pages 1658.
Crossref
Natalia Menshutina, Andrey Abramov & Elizaveta Mokhova. (2023) Mathematical and Computer Modeling as a Novel Approach for the Accelerated Development of New Inhalation and Intranasal Drug Delivery Systems. Computation 11:7, pages 136.
Crossref
Sahar Awwad, Nkiruka Ibeanu, Tianyang Liu, Angeliki Velentza-Almpani, Nerisha Chouhan, Stavros Vlatakis, Peng Tee Khaw, Steve Brocchini & Yann Bouremel. (2023) Real-Time Monitoring Platform for Ocular Drug Delivery. Pharmaceutics 15:5, pages 1444.
Crossref
Xiaoge Duan, Hai-lan Chen & Chunxian Guo. (2022) Polymeric Nanofibers for Drug Delivery Applications: A Recent Review. Journal of Materials Science: Materials in Medicine 33:12.
Crossref
Daljeet Singh Dhanjal, Parvarish Sharma, Meenu Mehta, Murtaza M Tambuwala, Parteek Prasher, Keshav R Paudel, Gang Liu, Shakti D Shukla, Philip M Hansbro, Dinesh Kumar Chellappan, Kamal Dua & Saurabh Satija. (2022) Concepts of advanced therapeutic delivery systems for the management of remodeling and inflammation in airway diseases. Future Medicinal Chemistry 14:4, pages 271-288.
Crossref
Huimin Beng, Junhua Hu, Rui Zhang, Yapeng Huang, Xi Chen & Wen Tan. (2021) Quantitative DESI mass spectrometry imaging of lung distribution of inhaled drug. Journal of Drug Delivery Science and Technology 66, pages 102794.
Crossref
Maria Helena Macedo, Ana Baião, Soraia Pinto, Andreia S. Barros, Helena Almeida, Andreia Almeida, José das Neves & Bruno Sarmento. (2021) Mucus-producing 3D cell culture models. Advanced Drug Delivery Reviews 178, pages 113993.
Crossref
Jan Papies, Jackson Emanuel, Nicolas Heinemann, Žarko Kulić, Simon Schroeder, Beate Tenner, Martin D. Lehner, Georg Seifert & Marcel A. Müller. (2021) Antiviral and Immunomodulatory Effects of Pelargonium sidoides DC. Root Extract EPs® 7630 in SARS-CoV-2-Infected Human Lung Cells. Frontiers in Pharmacology 12.
Crossref
Chang Xu, Xin Zheng & Shifei Shen. (2021) A numerical study of the effects of ambient temperature and humidity on the particle growth and deposition in the human airway. Environmental Research 200, pages 111751.
Crossref
Andreia Sofia Barros, Ana Costa & Bruno Sarmento. (2021) Building three-dimensional lung models for studying pharmacokinetics of inhaled drugs. Advanced Drug Delivery Reviews 170, pages 386-395.
Crossref
Fen Huang, Qixuan Zhu, Xudong Zhou, Dazhao Gou, Jiaqi Yu, Renjie Li, Zhenbo Tong & Runyu Yang. (2021) Role of CFD based in silico modelling in establishing an in vitro-in vivo correlation of aerosol deposition in the respiratory tract. Advanced Drug Delivery Reviews 170, pages 369-385.
Crossref
Bingzhi Li, Peng Zhang, Bin Zhou, Siying Xie, Anqi Xia, Tiying Suo, Shuang Feng & Xing Zhang. (2021) Fluorometric detection of cancer marker FEN1 based on double-flapped dumbbell DNA nanoprobe functionalized with silver nanoclusters. Analytica Chimica Acta 1148, pages 238194.
Crossref
Michael Y.T. Chow, Yingshan Qiu & Jenny K.W. Lam. (2020) Inhaled RNA Therapy: From Promise to Reality. Trends in Pharmacological Sciences 41:10, pages 715-729.
Crossref
Sahar Awwad, Christin Henein, Nkiruka Ibeanu, Peng T. Khaw & Steve Brocchini. (2020) Preclinical challenges for developing long acting intravitreal medicines. European Journal of Pharmaceutics and Biopharmaceutics 153, pages 130-149.
Crossref
Tao-Tao Fu, Yun Zhao, Fei-Fei Yang, Han Wen, Chun-Yu Liu & Yong-Hong Liao. (2018) Ciclesonide and budesonide suspensions for nebulization delivery: An in vivo inhalation biopharmaceutics investigation. International Journal of Pharmaceutics 549:1-2, pages 21-30.
Crossref
Dania Movia, Despina Bazou, Yuri Volkov & Adriele Prina-Mello. (2018) Multilayered Cultures of NSCLC cells grown at the Air-Liquid Interface allow the efficacy testing of inhaled anti-cancer drugs. Scientific Reports 8:1.
Crossref
Aysu Yurdasiper, Mesut Arıcı & Mine Ozyazici. 2018. Emerging Nanotechnologies in Immunology. Emerging Nanotechnologies in Immunology 165 201 .
Rodrigo S. Heyder, Qian Zhong, Reinaldo C. Bazito & Sandro R.P. da Rocha. (2017) Cellular internalization and transport of biodegradable polyester dendrimers on a model of the pulmonary epithelium and their formulation in pressurized metered-dose inhalers. International Journal of Pharmaceutics 520:1-2, pages 181-194.
Crossref
Brian F. Thomas & Mahmoud A. ElSohly. 2016. The Analytical Chemistry of Cannabis. The Analytical Chemistry of Cannabis 83 99 .
Sahar Awwad, Alastair Lockwood, Steve Brocchini & Peng T. Khaw. (2015) The PK-Eye: A Novel In Vitro Ocular Flow Model for Use in Preclinical Drug Development. Journal of Pharmaceutical Sciences 104:10, pages 3330-3342.
Crossref
Jens Markus Borghardt, Benjamin Weber, Alexander Staab & Charlotte Kloft. (2015) Pharmacometric Models for Characterizing the Pharmacokinetics of Orally Inhaled Drugs. The AAPS Journal 17:4, pages 853-870.
Crossref
Balaji Bharatwaj, Abdul Khader Mohammad, Radovan Dimovski, Fernando L. Cassio, Reinaldo C. Bazito, Denise Conti, Qiang Fu, Joshua Reineke & Sandro R. P. da Rocha. (2015) Dendrimer Nanocarriers for Transport Modulation Across Models of the Pulmonary Epithelium. Molecular Pharmaceutics 12:3, pages 826-838.
Crossref
John N Pritchard & Rachael D Giles. (2014) Opportunities in respiratory drug delivery. Therapeutic Delivery 5:12, pages 1261-1273.
Crossref
Mehra Haghi, Daniela Traini & Paul Young. (2014) In Vitro Cell Integrated Impactor Deposition Methodology for the Study of Aerodynamically Relevant Size Fractions from Commercial Pressurised Metered Dose Inhalers. Pharmaceutical Research 31:7, pages 1779-1787.
Crossref
Kathryn A. Whitehead, J. Robert Dorkin, Arturo J. Vegas, Philip H. Chang, Omid Veiseh, Jonathan Matthews, Owen S. Fenton, Yunlong Zhang, Karsten T. Olejnik, Volkan Yesilyurt, Delai Chen, Scott Barros, Boris Klebanov, Tatiana Novobrantseva, Robert Langer & Daniel G. Anderson. (2014) Degradable lipid nanoparticles with predictable in vivo siRNA delivery activity. Nature Communications 5:1.
Crossref
Jessica M. Oakes, Alison L. Marsden, Celine Grandmont, Shawn C. Shadden, Chantal Darquenne & Irene E. Vignon-Clementel. (2013) Airflow and Particle Deposition Simulations in Health and Emphysema: From In Vivo to In Silico Animal Experiments. Annals of Biomedical Engineering 42:4, pages 899-914.
Crossref
Moritz Beck-Broichsitter, Alexandra C. Dalla-Bona, Thomas Kissel, Werner Seeger & Thomas Schmehl. 2014. Drug Delivery System. Drug Delivery System 133 145 .
Ciara Kelly, Awadh B. Yadav, Paul J. McKiernan, Catherine M. Greene & Sally-Ann Cryan. 2013. Advanced Delivery and Therapeutic Applications of RNAi. Advanced Delivery and Therapeutic Applications of RNAi 391 416 .
Moritz Beck-Broichsitter, Monika Rieger, Regina Reul, Tobias Gessler, Werner Seeger & Thomas Schmehl. (2013) Correlation of drug release with pulmonary drug absorption profiles for nebulizable liposomal formulations. European Journal of Pharmaceutics and Biopharmaceutics 84:1, pages 106-114.
Crossref
Paola Russo, Mariateresa Stigliani, Lucia Prota, Giulia Auriemma, Carlo Crescenzi, Amalia Porta & Rita P. Aquino. (2013) Gentamicin and leucine inhalable powder: What about antipseudomonal activity and permeation through cystic fibrosis mucus?. International Journal of Pharmaceutics 440:2, pages 250-255.
Crossref
Moritz Beck-Broichsitter, Olivia M. Merkel & Thomas Kissel. (2012) Controlled pulmonary drug and gene delivery using polymeric nano-carriers. Journal of Controlled Release 161:2, pages 214-224.
Crossref
Moritz Beck-Broichsitter, Christoph Schweiger, Thomas Schmehl, Tobias Gessler, Werner Seeger & Thomas Kissel. (2012) Characterization of novel spray-dried polymeric particles for controlled pulmonary drug delivery. Journal of Controlled Release 158:2, pages 329-335.
Crossref
Sebastian G. Klein, Jenny Hennen, Tommaso Serchi, Brunhilde Blömeke & Arno C. Gutleb. (2011) Potential of coculture in vitro models to study inflammatory and sensitizing effects of particles on the lung. Toxicology in Vitro 25:8, pages 1516-1534.
Crossref

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.