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Expert Opinion on Drug Delivery Volume 9, 2012 - Issue 3
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Novel formulation and drug delivery strategies for the treatment of pediatric poverty-related diseases

Alejandro SosnikUniversity of Buenos Aires, Faculty of Pharmacy and Biochemistry, Department of Pharmaceutical Technology,The Group of Biomaterials and Nanotechnology for Improved Medicines (BIONIMED), 956 Junín St., Buenos Aires CP1113, [email protected];National Science Research Council (CONICET), Buenos Aires, Argentina
, PhD,
Katia P SeremetaUniversity of Buenos Aires, Faculty of Pharmacy and Biochemistry, Department of Pharmaceutical Technology,The Group of Biomaterials and Nanotechnology for Improved Medicines (BIONIMED), 956 Junín St., Buenos Aires CP1113, [email protected];National Science Research Council (CONICET), Buenos Aires, Argentina
, PharmB,
Julieta C ImperialeUniversity of Buenos Aires, Faculty of Pharmacy and Biochemistry, Department of Pharmaceutical Technology,The Group of Biomaterials and Nanotechnology for Improved Medicines (BIONIMED), 956 Junín St., Buenos Aires CP1113, [email protected]
, PharmB &
Diego A ChiappettaUniversity of Buenos Aires, Faculty of Pharmacy and Biochemistry, Department of Pharmaceutical Technology,The Group of Biomaterials and Nanotechnology for Improved Medicines (BIONIMED), 956 Junín St., Buenos Aires CP1113, [email protected];National Science Research Council (CONICET), Buenos Aires, Argentina
, PhD
Pages 303-323 | Published online: 19 Jan 2012

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Konstantina Chachlioutaki, Christos Gioumouxouzis, Christina Karavasili & Dimitrios G. Fatouros. (2023) Small patients, big challenges: navigating pediatric drug manipulations to prevent medication errors - a comprehensive review. Expert Opinion on Drug Delivery 0:0, pages 1-21.
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Christian Höcht, Miguel A Allo, Ariel Héctor Polizio, Marcela A Morettón, Andrea Carranza, Diego A Chiappetta & Marcelo Roberto Choi. (2022) New and developing pharmacotherapies for hypertension. Expert Review of Cardiovascular Therapy 20:8, pages 647-666.
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Raphael Wiedey, Marcel Kokott & Jörg Breitkreutz. (2021) Orodispersible tablets for pediatric drug delivery: current challenges and recent advances. Expert Opinion on Drug Delivery 18:12, pages 1873-1890.
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Subham Banerjee, Subhadeep Roy, Kaushik Nath Bhaumik & Jonathan Pillai. (2020) Mechanisms of the effectiveness of lipid nanoparticle formulations loaded with anti-tubercular drugs combinations toward overcoming drug bioavailability in tuberculosis. Journal of Drug Targeting 28:1, pages 55-69.
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Felipe L Lopez, Terry B Ernest, Catherine Tuleu & Mine Orlu Gul. (2015) Formulation approaches to pediatric oral drug delivery: benefits and limitations of current platforms. Expert Opinion on Drug Delivery 12:11, pages 1727-1740.
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Julieta C. Imperiale, Gabriela Bevilacqua, Paulo de Tarso Vieira e Rosa & Alejandro Sosnik. (2014) Production of pure indinavir free base nanoparticles by a supercritical anti-solvent (SAS) method. Drug Development and Industrial Pharmacy 40:12, pages 1607-1615.
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Annemarie Rosan Kreeftmeijer-Vegter, Mariska de Meijer, Kim AM Wegman & Cees KW van Veldhuizen. (2013) Development and evaluation of age-appropriate film-coated tablets of levamisole for paediatric use (2 – 18 years) . Expert Opinion on Drug Delivery 10:3, pages 293-300.
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Articles from other publishers (29)

Doris Klingelhöfer, Markus Braun, Dörthe Brüggmann & David A. Groneberg. (2022) Does health-related poverty publication landscape reflect global needs in the light of the current poverty rebound?. Globalization and Health 18:1.
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Allan M. Ciciriello, Jessica K. Fairley, Emma Cooke, Paul M. Emerson, Pamela J. Hooper, Birgit Bolton, Genevieve LaCon & David G. Addiss. (2022) Safety of integrated preventive chemotherapy for neglected tropical diseases. PLOS Neglected Tropical Diseases 16:9, pages e0010700.
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Hemant A. DeokuleSmita S. PimpleKiran C. MahajanPraveen D. Chaudhari. (2022) Fabrication and Evaluation of Solid Self Emulsifying Drug Delivery System of Dolutegravir sodium by using Adsorption to Solid Carrier Techniques. Research Journal of Pharmacy and Technology, pages 4158-4165.
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Lehlogonolo N. F. Maphalle, Bozena B. Michniak-Kohn, Modupe O. Ogunrombi & Oluwatoyin A. Adeleke. (2022) Pediatric Tuberculosis Management: A Global Challenge or Breakthrough?. Children 9:8, pages 1120.
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Arnau Guasch-Girbau & Xavier Fernàndez-Busquets. (2021) Review of the Current Landscape of the Potential of Nanotechnology for Future Malaria Diagnosis, Treatment, and Vaccination Strategies. Pharmaceutics 13:12, pages 2189.
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Laura Carolina Luciani-Giacobbe, Augusto Matías Lorenzutti, Nicolás Javier Litterio, María Verónica Ramírez-Rigo & María Eugenia Olivera. (2020) Anti-tuberculosis site-specific oral delivery system that enhances rifampicin bioavailability in a fixed-dose combination with isoniazid. Drug Delivery and Translational Research 11:3, pages 894-908.
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Mohammed S. Alqahtani, Mohsin Kazi, Mohammad A. Alsenaidy & Muhammad Z. Ahmad. (2021) Advances in Oral Drug Delivery. Frontiers in Pharmacology 12.
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Moemen M. Salama & Ahmed O. Elzoghby. 2021. Theory and Applications of Nonparenteral Nanomedicines. Theory and Applications of Nonparenteral Nanomedicines 113 136 .
Enrica Chiesa, Luca Monti, Chiara Paganini, Rossella Dorati, Bice Conti, Tiziana Modena, Antonio Rossi & Ida Genta. (2017) Polyethylene Glycol-Poly-Lactide-co-Glycolide Block Copolymer-Based Nanoparticles as a Potential Tool for Off-Label Use of N-Acetylcysteine in the Treatment of Diastrophic Dysplasia. Journal of Pharmaceutical Sciences 106:12, pages 3631-3641.
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Gueorgui Dubrocq, Natella Rakhmanina & B. Ryan Phelps. (2017) Challenges and Opportunities in the Development of HIV Medications in Pediatric Patients. Pediatric Drugs 19:2, pages 91-98.
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Sejal R. Ranmal, Anne Cram & Catherine Tuleu. (2016) Age-appropriate and acceptable paediatric dosage forms: Insights into end-user perceptions, preferences and practices from the Children’s Acceptability of Oral Formulations (CALF) Study. International Journal of Pharmaceutics 514:1, pages 296-307.
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Marco Giardiello, Neill J. Liptrott, Tom O. McDonald, Darren Moss, Marco Siccardi, Phil Martin, Darren Smith, Rohan Gurjar, Steve P. Rannard & Andrew Owen. (2016) Accelerated oral nanomedicine discovery from miniaturized screening to clinical production exemplified by paediatric HIV nanotherapies. Nature Communications 7:1.
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Taskeen Niaz, Habib Nasir, Saima Shabbir, Asma Rehman & Muhammad Imran. (2016) Polyionic hybrid nano-engineered systems comprising alginate and chitosan for antihypertensive therapeutics. International Journal of Biological Macromolecules 91, pages 180-187.
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Jalashri Patadia, Rahul Tripathi & Amita Joshi. (2015) Melt-in-Mouth Multi-particulate System for the Treatment of ADHD: A Convenient Platform for Pediatric Use. AAPS PharmSciTech 17:4, pages 878-890.
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Adrienne F. Schlatter, Andrew R. Deathe & Rachel C. Vreeman. (2016) The Need for Pediatric Formulations to Treat Children with HIV. AIDS Research and Treatment 2016, pages 1-8.
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Thanh Huong Hoang Thi, Siham Lhafidi, Simone Pinto Carneiro & Marie-Pierre Flament. (2015) Feasability of a new process to produce fast disintegrating pellets as novel multiparticulate dosage form for pediatric use. International Journal of Pharmaceutics 496:2, pages 842-849.
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D. Nagasamy Venkatesh, Mahendran Baskaran, Veera Venkata Satyanarayana Reddy Karri, Sai Sandeep Mannemala, Kollipara Radhakrishna & Sandip Goti. (2015) Fabrication and in vivo evaluation of Nelfinavir loaded PLGA nanoparticles for enhancing oral bioavailability and therapeutic effect. Saudi Pharmaceutical Journal 23:6, pages 667-674.
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Ramona Trastullo, Luisa Stella Dolci, Nadia Passerini & Beatrice Albertini. (2015) Development of flexible and dispersible oral formulations containing praziquantel for potential schistosomiasis treatment of pre-school age children. International Journal of Pharmaceutics 495:1, pages 536-550.
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Alejandro Sosnik & Maya Menaker Raskin. (2015) Polymeric micelles in mucosal drug delivery: Challenges towards clinical translation. Biotechnology Advances 33:6, pages 1380-1392.
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Julieta C Imperiale & Alejandro D Sosnik. (2015) Cyclodextrin complexes for treatment improvement in infectious diseases. Nanomedicine 10:10, pages 1621-1641.
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Julieta C. Imperiale, Pablo Nejamkin, Maria J. del Sole, Carlos E. Lanusse & Alejandro Sosnik. (2015) Novel protease inhibitor-loaded Nanoparticle-in-Microparticle Delivery System leads to a dramatic improvement of the oral pharmacokinetics in dogs. Biomaterials 37, pages 383-394.
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Alejandro Sosnik, José das Neves & Bruno Sarmento. (2014) Mucoadhesive polymers in the design of nano-drug delivery systems for administration by non-parenteral routes: A review. Progress in Polymer Science 39:12, pages 2030-2075.
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Marcela A. Moretton, Carlos Taira, Sabrina Flor, Ezequiel Bernabeu, Silvia Lucangioli, Christian Höcht & Diego A. Chiappetta. (2014) Novel nelfinavir mesylate loaded d -α-tocopheryl polyethylene glycol 1000 succinate micelles for enhanced pediatric anti HIV therapy: In vitro characterization and in vivo evaluation. Colloids and Surfaces B: Biointerfaces 123, pages 302-310.
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Marcela A Moretton, Christian Hocht, Carlos Taira & Alejandro Sosnik. (2014) Rifampicin-loaded ‘flower-like’ polymeric micelles for enhanced oral bioavailability in an extemporaneous liquid fixed-dose combination with isoniazid. Nanomedicine 9:11, pages 1635-1650.
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Alejandro Sosnik & Angel M. Carcaboso. (2014) Nanomedicines in the future of pediatric therapy. Advanced Drug Delivery Reviews 73, pages 140-161.
Crossref
Alejandro Sosnik. (2014) Alginate Particles as Platform for Drug Delivery by the Oral Route: State-of-the-Art. ISRN Pharmaceutics 2014, pages 1-17.
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M. Fawzi Mahomoodally & D. Priyamka Sreekeesoon. (2014) A Quantitative Ethnopharmacological Documentation of Natural Pharmacological Agents Used by Pediatric Patients in Mauritius. BioMed Research International 2014, pages 1-14.
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Sejal R. Ranmal, Susan A. Barker & Catherine Tuleu. 2014. Pediatric Formulations. Pediatric Formulations 153 170 .
Anne Zajicek. 2013. Pediatric Drug Development. Pediatric Drug Development 576 582 .

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